Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration

Frontiers in Neuroscience

Volumn 12, Issue JUL, 2018, Pages

  Abdalkader, Moataz ^a   Lampinen, Riikka ^a   Kanninen, Katja M ^a   Malm, Tarja M ^a   Liddell, Jeffrey R ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Alzheimer's disease; Erastin; Huntington's disease; Keap1; Motor neuron disease; Parkinson's disease; RSL3; System xc

Indexed keywords

ADRENIC ACID; ALPHA TOCOPHEROL; APOPTOSIS INDUCING FACTOR; ARACHIDONIC ACID; CISD1 PROTEIN; CYSTEINE; DEFERIPRONE; DEFEROXAMINE; FERRITIN; FERROSTATIN 1; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE REDUCTASE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LIPID PEROXIDE; LIPROXSTATIN 1; MALATE DEHYDROGENASE (DECARBOXYLATING); MEMBRANE PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLETHANOLAMINE; PHOSPHOGLUCONATE DEHYDROGENASE; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; PROTEIN BID; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APOPTOSIS; CELL DEATH; DENSITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FERROPTOSIS; GENE KNOCKDOWN; GENE KNOCKOUT; GENE OVEREXPRESSION; GENE TRANSLOCATION; GLUTATHIONE METABOLISM; HUMAN; HUNTINGTON CHOREA; IRON CHELATION; LIPID PEROXIDATION; MEMBRANE RUPTURE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL MEMBRANE DENSITY; MITOCHONDRION; MITOCHONDRION SWELLING; MOTOR NEURON DISEASE; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NONHUMAN; NRF2 SIGNALING PATHWAY; OXIDATIVE STRESS; OXYTOSIS; PARKINSON DISEASE; SHORT SURVEY; SIGNAL TRANSDUCTION; TRANSACTIVATION; TRANSCRIPTION REGULATION;

EID: 85050006428     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2018.00466     Document Type: Short Survey

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