Neuronal Death after Hemorrhagic Stroke in Vitro and in Vivo Shares Features of Ferroptosis and Necroptosis

Stroke

Volumn 48, Issue 4, 2017, Pages 1033-1043

  Zille, Marietta ^a,b   Karuppagounder, Saravanan S ^a,b   Chen, Yingxin ^a,b   Gough, Peter J ^c   Bertin, John ^d   Finger, Joshua ^d   Milner, Teresa A ^b,e   Jonas, Elizabeth A ^f   Ratan, Rajiv R ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b FEIL FAMILY BRAIN AND MIND RESEARCH INSTITUTE   (United States)

^c Infectious Diseases Therapy Area Unit   (United States)

^d Glaxo SmithKline   (United States)

^e ROCKEFELLER UNIVERSITY   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

apoptosis; cell death; ferroptosis; intracerebral hemorrhage; necrosis

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ACETYLCYSTEINE; BETA ACTIN; CASPASE; CHONDROITIN SULFATE IRON; DEFEROXAMINE; GAMMA TUBULIN; HEMIN; HEMOGLOBIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MOLECULAR MARKER; RIP1 PROTEIN; RIP3 PROTEIN; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN CELL CULTURE; BRAIN HEMORRHAGE; BRAIN NERVE CELL; CELL DEATH; CONTROLLED STUDY; ELECTRON MICROSCOPY; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MITOPHAGY; MORPHOLOGICAL TRAIT; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; THERAPEUTIC INDEX; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; MALE; METABOLISM; NECROSIS; NERVE CELL;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBRAL HEMORRHAGE; DISEASE MODELS, ANIMAL; HEMIN; HEMOGLOBINS; MALE; MICE; MICE, INBRED C57BL; NECROSIS; NEURONS;

EID: 85014110484     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.116.015609     Document Type: Article

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