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Volumn 6, Issue 8, 2017, Pages

Nrf2-keap1 pathway promotes cell proliferation and diminishes ferroptosis

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EID: 85034628793     PISSN: None     EISSN: 21579024     Source Type: Journal    
DOI: 10.1038/oncsis.2017.65     Document Type: Article
Times cited : (490)

References (49)
  • 1
    • 84938765962 scopus 로고    scopus 로고
    • The Keap1/Nrf2 pathway in health and disease: From the bench to the clinic
    • O'Connell MA, Hayes JD. The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic. Biochem Soc Trans 2015; 43: 687–689.
    • (2015) Biochem Soc Trans , vol.43 , pp. 687-689
    • O'connell, M.A.1    Hayes, J.D.2
  • 2
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011; 144: 646–674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 3
    • 0028061444 scopus 로고
    • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region
    • Moi P, Chan K, Asunis I, Cao A, Kan YW. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 1994; 91: 9926–9930.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 9926-9930
    • Moi, P.1    Chan, K.2    Asunis, I.3    Cao, A.4    Kan, Y.W.5
  • 5
    • 0030451213 scopus 로고    scopus 로고
    • NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and devel-opment
    • Chan K, Lu R, Chang J. C, Kan Y. W. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and devel-opment. Proc Natl Acad Sci USA 1996; 93: 13943–13948.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13943-13948
    • Chan, K.1    Lu, R.2    Chang, J.C.3    Kan, Y.W.4
  • 6
    • 85020743035 scopus 로고    scopus 로고
    • NRF2 induction supporting breast cancer cell survival is enabled by oxidative stress-induced DPP3-KEAP1 interaction
    • Lu K, Alcivar AL, Ma J, Foo TK, Zywea S, Mahdi A et al. NRF2 induction supporting breast cancer cell survival is enabled by oxidative stress-induced DPP3-KEAP1 interaction. Cancer Res 2017; 77: 2881–2892.
    • (2017) Cancer Res , vol.77 , pp. 2881-2892
    • Lu, K.1    Alcivar, A.L.2    Ma, J.3    Foo, T.K.4    Zywea, S.5    Mahdi, A.6
  • 7
    • 33845442925 scopus 로고    scopus 로고
    • Mechanistic studies of the Nrf2-Keap1 signaling pathway
    • Zhang DD. Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev 2006; 38: 769–789.
    • (2006) Drug Metab Rev , vol.38 , pp. 769-789
    • Zhang, D.D.1
  • 9
    • 2942746263 scopus 로고    scopus 로고
    • Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis
    • Ikeda H, Nishi S, Sakai M. Transcription factor Nrf2/MafK regulates rat placental glutathione S-transferase gene during hepatocarcinogenesis. Biochem J 2004; 380: 515–521.
    • (2004) Biochem J , vol.380 , pp. 515-521
    • Ikeda, H.1    Nishi, S.2    Sakai, M.3
  • 10
    • 76749106638 scopus 로고    scopus 로고
    • Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin
    • Kim YR, Oh JE, Kim MS, Kang MR, Park SW, Han JY et al. Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin. J Pathol 2010; 220: 446–451.
    • (2010) J Pathol , vol.220 , pp. 446-451
    • Kim, Y.R.1    Oh, J.E.2    Kim, M.S.3    Kang, M.R.4    Park, S.W.5    Han, J.Y.6
  • 11
  • 12
    • 84925686332 scopus 로고    scopus 로고
    • Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress
    • Habib E, Linher-Melville K, Lin HX, Singh G. Expression of xCT and activity of system xc(-) are regulated by NRF2 in human breast cancer cells in response to oxidative stress. Redox Biol 2015; 5: 33–42.
    • (2015) Redox Biol , vol.5 , pp. 33-42
    • Habib, E.1    Linher-Melville, K.2    Lin, H.X.3    Singh, G.4
  • 13
    • 70349314704 scopus 로고    scopus 로고
    • Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro
    • Lewerenz J, Albrecht P, Tien ML, Henke N, Karumbayaram S, Kornblum HI et al. Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro. J Neurochem 2009; 111: 332–343.
    • (2009) J Neurochem , vol.111 , pp. 332-343
    • Lewerenz, J.1    Albrecht, P.2    Tien, M.L.3    Henke, N.4    Karumbayaram, S.5    Kornblum, H.I.6
  • 14
    • 84906054877 scopus 로고    scopus 로고
    • Nrf2-and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition
    • Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A et al. Nrf2-and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition. Mol Cell Biol 2014; 34: 3421–3434.
    • (2014) Mol Cell Biol , vol.34 , pp. 3421-3434
    • Ye, P.1    Mimura, J.2    Okada, T.3    Sato, H.4    Liu, T.5    Maruyama, A.6
  • 15
    • 77956615063 scopus 로고    scopus 로고
    • Eyupoglu IY xCT modulation in gliomas: Relevance to energy metabolism and tumor microenvironment normalization
    • Savaskan N. E. Eyupoglu IY xCT modulation in gliomas: relevance to energy metabolism and tumor microenvironment normalization. Anna Anat 2010; 192: 309–313.
    • (2010) Anna Anat , vol.192 , pp. 309-313
    • Savaskan, N.E.1
  • 17
    • 84978141675 scopus 로고    scopus 로고
    • Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema
    • Sehm T, Fan Z, Ghoochani A, Rauh M, Engelhorn T, Minakaki G et al. Sulfasalazine impacts on ferroptotic cell death and alleviates the tumor microenvironment and glioma-induced brain edema. Oncotarget 2016; 7: 36021–36033.
    • (2016) Oncotarget , vol.7 , pp. 36021-36033
    • Sehm, T.1    Fan, Z.2    Ghoochani, A.3    Rauh, M.4    Engelhorn, T.5    Minakaki, G.6
  • 18
    • 44949122670 scopus 로고    scopus 로고
    • Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegen-eration and alleviates brain edema
    • Savaskan NE, Heckel A, Hahnen E, Engelhorn T, Doerfler A, Ganslandt O et al. Small interfering RNA-mediated xCT silencing in gliomas inhibits neurodegen-eration and alleviates brain edema. Nat Med 2008; 14: 629–632.
    • (2008) Nat Med , vol.14 , pp. 629-632
    • Savaskan, N.E.1    Heckel, A.2    Hahnen, E.3    Engelhorn, T.4    Doerfler, A.5    Ganslandt, O.6
  • 20
    • 84872119581 scopus 로고    scopus 로고
    • Tracking the seed and tending the soil: Evolving concepts in meta-static breast cancer
    • Comen E. A. Tracking the seed and tending the soil: evolving concepts in meta-static breast cancer. Discov Med 2012; 14: 97–104.
    • (2012) Discov Med , vol.14 , pp. 97-104
    • Comen, E.A.1
  • 21
    • 84907639270 scopus 로고    scopus 로고
    • To "grow" or "go": TMEM16A expression as a switch between tumor growth and metastasis in SCCHN
    • Shiwarski D. J, Shao C, Bill A, Kim J, Xiao D, Bertrand C. A et al. To "grow" or "go": TMEM16A expression as a switch between tumor growth and metastasis in SCCHN. Clinical Cancer Res 2014; 20: 4673–4688.
    • (2014) Clinical Cancer Res , vol.20 , pp. 4673-4688
    • Shiwarski, D.J.1    Shao, C.2    Bill, A.3    Kim, J.4    Xiao, D.5    Bertrand, C.A.6
  • 22
    • 85008704819 scopus 로고    scopus 로고
    • Aspirin plus sorafenib potentiates cisplatin cytotoxicity in resistant head and neck cancer cells through xCT inhibition
    • Roh J. L, Kim E. H, Jang H, Shin D. Aspirin plus sorafenib potentiates cisplatin cytotoxicity in resistant head and neck cancer cells through xCT inhibition. Free Radical Biol Mede 2017; 104: 1–9.
    • (2017) Free Radical Biol Mede , vol.104 , Issue.1-9
    • Roh, J.L.1    Kim, E.H.2    Jang, H.3    Shin, D.4
  • 23
    • 40849085503 scopus 로고    scopus 로고
    • Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells
    • Yang W. S, Stockwell B. R. Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells. Chem Biol 2008; 15: 234–245.
    • (2008) Chem Biol , vol.15 , pp. 234-245
    • Yang, W.S.1    Stockwell, B.R.2
  • 25
    • 85026210212 scopus 로고    scopus 로고
    • The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas
    • e-pub ahead of print 9 May 2017
    • Chen D, Rauh M, Buchfelder M, Eyupoglu IY, Savaskan NE. The oxido-metabolic driver ATF4 enhances temozolamide chemo-resistance in human gliomas. Oncotarget (e-pub ahead of print 9 May 2017; doi:10.18632/oncotarget.17737).
    • Oncotarget
    • Chen, D.1    Rauh, M.2    Buchfelder, M.3    Eyupoglu, I.Y.4    Savaskan, N.E.5
  • 26
    • 84878187382 scopus 로고    scopus 로고
    • Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model
    • Ji XJ, Chen SH, Zhu L, Pan H, Zhou Y, Li W et al. Knockdown of NF-E2-related factor 2 inhibits the proliferation and growth of U251MG human glioma cells in a mouse xenograft model. Oncol Rep 2013; 30: 157–164.
    • (2013) Oncol Rep , vol.30 , pp. 157-164
    • Ji, X.J.1    Chen, S.H.2    Zhu, L.3    Pan, H.4    Zhou, Y.5    Li, W.6
  • 27
    • 84988353997 scopus 로고    scopus 로고
    • Clinical implication of Keap1 and phosphorylated Nrf2 expression in hepatocellular carcinoma
    • Chen J, Yu Y, Ji T, Ma R, Chen M, Li G et al. Clinical implication of Keap1 and phosphorylated Nrf2 expression in hepatocellular carcinoma. Cancer Med 2016; 5: 2678–2687.
    • (2016) Cancer Med , vol.5 , pp. 2678-2687
    • Chen, J.1    Yu, Y.2    Ji, T.3    Ma, R.4    Chen, M.5    Li, G.6
  • 28
    • 85022209277 scopus 로고    scopus 로고
    • Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer
    • Tong YH, Zhang B, Yan YY, Fan Y, Yu JW, Kong SS et al. Dual-negative expression of Nrf2 and NQO1 predicts superior outcomes in patients with non-small cell lung cancer. Oncotarget 2017; 8: 45750–45758.
    • (2017) Oncotarget , vol.8 , pp. 45750-45758
    • Tong, Y.H.1    Zhang, B.2    Yan, Y.Y.3    Fan, Y.4    Yu, J.W.5    Kong, S.S.6
  • 29
    • 35848932314 scopus 로고    scopus 로고
    • Overexpression of heme oxygenase-1 in murine melanoma: Increased proliferation and viability of tumor cells, decreased survival of mice
    • Was H, Cichon T, Smolarczyk R, Rudnicka D, Stopa M, Chevalier Cet al. Overexpression of heme oxygenase-1 in murine melanoma: increased proliferation and viability of tumor cells, decreased survival of mice. Am J Pathol 2006; 169: 2181–2198.
    • (2006) Am J Pathol , vol.169 , pp. 2181-2198
    • Was, H.1    Cichon, T.2    Smolarczyk, R.3    Rudnicka, D.4    Stopa, M.5    Chevaliercet6
  • 30
    • 84856756216 scopus 로고    scopus 로고
    • Nrf2 knockdown by shRNA inhibits tumor growth and increases efficacy of chemotherapy in cervical cancer
    • Ma X, Zhang J, Liu S, Huang Y, Chen B, Wang D. Nrf2 knockdown by shRNA inhibits tumor growth and increases efficacy of chemotherapy in cervical cancer. Cancer Chemother Pharmacol 2012; 69: 485–494.
    • (2012) Cancer Chemother Pharmacol , vol.69 , pp. 485-494
    • Ma, X.1    Zhang, J.2    Liu, S.3    Huang, Y.4    Chen, B.5    Wang, D.6
  • 31
    • 66149168685 scopus 로고    scopus 로고
    • Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer
    • Homma S, Ishii Y, Morishima Y, Yamadori T, Matsuno Y, Haraguchi N et al. Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer. Clin Cancer Res 2009; 15: 3423–3432.
    • (2009) Clin Cancer Res , vol.15 , pp. 3423-3432
    • Homma, S.1    Ishii, Y.2    Morishima, Y.3    Yamadori, T.4    Matsuno, Y.5    Haraguchi, N.6
  • 32
    • 79953889329 scopus 로고    scopus 로고
    • Nrf2 is overexpressed in pancreatic cancer: Implications for cell proliferation and therapy
    • Lister A, Nedjadi T, Kitteringham NR, Campbell F, Costello E, Lloyd B et al. Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. Mol Cancer 2011; 10: 37.
    • (2011) Mol Cancer , vol.10 , pp. 37
    • Lister, A.1    Nedjadi, T.2    Kitteringham, N.R.3    Campbell, F.4    Costello, E.5    Lloyd, B.6
  • 33
    • 53249154670 scopus 로고    scopus 로고
    • Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling
    • Reddy NM, Kleeberger SR, Bream JH, Fallon PG, Kensler TW, Yamamoto M et al. Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling. Oncogene 2008; 27: 5821–5832.
    • (2008) Oncogene , vol.27 , pp. 5821-5832
    • Reddy, N.M.1    Kleeberger, S.R.2    Bream, J.H.3    Fallon, P.G.4    Kensler, T.W.5    Yamamoto, M.6
  • 34
    • 70349970493 scopus 로고    scopus 로고
    • KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta
    • Lee D. F, Kuo H. P, Liu M, Chou C. K, Xia W, Du Y et al. KEAP1 E3 ligase-mediated downregulation of NF-kappaB signaling by targeting IKKbeta. Mol Cell 2009; 36: 131–140.
    • (2009) Mol Cell , vol.36 , pp. 131-140
    • Lee, D.F.1    Kuo, H.P.2    Liu, M.3    Chou, C.K.4    Xia, W.5    Du, Y.6
  • 35
    • 84897421970 scopus 로고    scopus 로고
    • The Nrf2 regulatory network provides an interface between redox and intermediary metabolism
    • Hayes JD, Dinkova-Kostova AT. The Nrf2 regulatory network provides an interface between redox and intermediary metabolism. Trends Biochem Sci 2014; 39: 199–218.
    • (2014) Trends Biochem Sci , vol.39 , pp. 199-218
    • Hayes, J.D.1    Dinkova-Kostova, A.T.2
  • 36
    • 84863764614 scopus 로고    scopus 로고
    • Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic repro-gramming
    • Mitsuishi Y, Taguchi K, Kawatani Y, Shibata T, Nukiwa T, Aburatani H et al. Nrf2 redirects glucose and glutamine into anabolic pathways in metabolic repro-gramming. Cancer Cell 2012; 22: 66–79.
    • (2012) Cancer Cell , vol.22 , pp. 66-79
    • Mitsuishi, Y.1    Taguchi, K.2    Kawatani, Y.3    Shibata, T.4    Nukiwa, T.5    Aburatani, H.6
  • 37
    • 84872579107 scopus 로고    scopus 로고
    • The involvement of Nrf2-ARE pathway in regulation of apoptosis in human glioblastoma cell U251
    • Pan H, Wang H, Zhu L, Wang X, Cong Z, Sun K et al. The involvement of Nrf2-ARE pathway in regulation of apoptosis in human glioblastoma cell U251. Neurol Res 2013; 35: 71–78.
    • (2013) Neurol Res , vol.35 , pp. 71-78
    • Pan, H.1    Wang, H.2    Zhu, L.3    Wang, X.4    Cong, Z.5    Sun, K.6
  • 38
    • 84872831679 scopus 로고    scopus 로고
    • Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line
    • Zhou Y, Wang H. D, Zhu L, Cong Z. X, Li N, Ji X. J et al. Knockdown of Nrf2 enhances autophagy induced by temozolomide in U251 human glioma cell line. Oncol Rep 2013; 29: 394–400.
    • (2013) Oncol Rep , vol.29 , pp. 394-400
    • Zhou, Y.1    Wang, H.D.2    Zhu, L.3    Cong, Z.X.4    Li, N.5    Ji, X.J.6
  • 39
    • 84865626729 scopus 로고    scopus 로고
    • The effects of nrf2 on tumor angiogenesis: A review of the possible mechanisms of action
    • Zhou S, Ye W, Zhang M, Liang J. The effects of nrf2 on tumor angiogenesis: a review of the possible mechanisms of action. Crit Rev Eukaryot Gene Expr 2012; 22: 149–160.
    • (2012) Crit Rev Eukaryot Gene Expr , vol.22 , pp. 149-160
    • Zhou, S.1    Ye, W.2    Zhang, M.3    Liang, J.4
  • 40
    • 0037160092 scopus 로고    scopus 로고
    • Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
    • Sasaki H, Sato H, Kuriyama-Matsumura K, Sato K, Maebara K, Wang H et al. Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. J Biol Chem 2002; 277: 44765–44771.
    • (2002) J Biol Chem , vol.277 , pp. 44765-44771
    • Sasaki, H.1    Sato, H.2    Kuriyama-Matsumura, K.3    Sato, K.4    Maebara, K.5    Wang, H.6
  • 41
    • 84969900554 scopus 로고    scopus 로고
    • Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
    • Part B
    • Tebay L. E, Robertson H, Durant S. T, Vitale S. R, Penning T. M, Dinkova-Kostova A. T et al. Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease. Free Radical Biol Med 2015; 88(Part B): 108–146.
    • (2015) Free Radical Biol Med , vol.88 , pp. 108-146
    • Tebay, L.E.1    Robertson, H.2    Durant, S.T.3    Vitale, S.R.4    Penning, T.M.5    Dinkova-Kostova, A.T.6
  • 42
    • 53049105119 scopus 로고    scopus 로고
    • Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer
    • Shibata T, Kokubu A, Gotoh M, Ojima H, Ohta T, Yamamoto M et al. Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer. Gastroenterology 2008; 135: 1358–1368 1368 e1351-1354.
    • (2008) Gastroenterology , vol.135 , pp. 1358-1368
    • Shibata, T.1    Kokubu, A.2    Gotoh, M.3    Ojima, H.4    Ohta, T.5    Yamamoto, M.6
  • 44
    • 77649286874 scopus 로고    scopus 로고
    • Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy
    • Ren J. H, He W. S, Nong L, Zhu Q. Y, Hu K, Zhang R. G et al. Acquired cisplatin resistance in human lung adenocarcinoma cells is associated with enhanced autophagy. Cancer Biother Radiopharm 2010; 25: 75–80.
    • (2010) Cancer Biother Radiopharm , vol.25 , pp. 75-80
    • Ren, J.H.1    He, W.S.2    Nong, L.3    Zhu, Q.Y.4    Hu, K.5    Zhang, R.G.6
  • 46
    • 76649144791 scopus 로고    scopus 로고
    • Plasticity-related gene 5 (PRG5) induces filo-podia and neurite growth and impedes lysophosphatidic acid-and nogo-A-mediated axonal retraction
    • Broggini T, Nitsch R, Savaskan NE. Plasticity-related gene 5 (PRG5) induces filo-podia and neurite growth and impedes lysophosphatidic acid-and nogo-A-mediated axonal retraction. Mol Biol Cell 2010; 21: 521–537.
    • (2010) Mol Biol Cell , vol.21 , pp. 521-537
    • Broggini, T.1    Nitsch, R.2    Savaskan, N.E.3
  • 47
    • 1642346273 scopus 로고    scopus 로고
    • Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference
    • Ui-Tei K, Naito Y, Takahashi F, Haraguchi T, Ohki-Hamazaki H, Juni A et al. Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference. Nucleic Acids Res 2004; 32: 936–948.
    • (2004) Nucleic Acids Res , vol.32 , pp. 936-948
    • Ui-Tei, K.1    Naito, Y.2    Takahashi, F.3    Haraguchi, T.4    Ohki-Hamazaki, H.5    Juni, A.6
  • 48
    • 0033615966 scopus 로고    scopus 로고
    • Rac downregulates Rho activity: Reciprocal balance between both GTPases determines cellular morphology and migratory behavior
    • Sander E. E, ten Klooster J. P, van Delft S, van der Kammen R. A, Collard J. G. Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior. JCellBiol1999; 147: 1009–1022.
    • (1999) Jcellbiol , vol.147 , pp. 1009-1022
    • Sander, E.E.1    Ten Klooster, J.P.2    van Delft, S.3    van der Kammen, R.A.4    Collard, J.G.5
  • 49
    • 34948910770 scopus 로고    scopus 로고
    • AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts
    • Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA et al. AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts. J Clin Invest 2007; 117: 2962–2973.
    • (2007) J Clin Invest , vol.117 , pp. 2962-2973
    • Zhang, J.1    Park, S.I.2    Artime, M.C.3    Summy, J.M.4    Shah, A.N.5    Bomser, J.A.6


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