Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

Hepatology

Volumn 63, Issue 1, 2016, Pages 173-184

  Sun, Xiaofang ^a   Ou, Zhanhui ^a   Chen, Ruochan ^b   Niu, Xiaohua ^a   Chen, De ^a   Kang, Rui ^b   Tang, Daolin ^a,b  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; HEME OXYGENASE 1; KELCH LIKE ECH ASSOCIATED PROTEIN 1; OXIDOREDUCTASE; PROTEIN P62; PROTEIN V MAF; SORAFENIB; TRANSCRIPTION FACTOR MAFG; TRANSCRIPTION FACTOR NRF2; IRON; KEAP1 PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN; P62 PROTEIN, HUMAN; RNA BINDING PROTEIN; SIGNAL PEPTIDE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL DEATH; FERROPTOSIS; HEPATOCELLULAR CARCINOMA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; METABOLIC ACTIVATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION; TUMOR XENOGRAFT; ANIMAL; C57BL MOUSE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL DEATH; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IRON; KELCH-LIKE ECH-ASSOCIATED PROTEIN 1; LIVER NEOPLASMS; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 84952639010     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28251     Document Type: Article

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