Oxidative stress induced by lipid peroxidation is related with inflammation of demyelination and neurodegeneration in multiple sclerosis

European Neurology

Volumn 72, Issue , 2014, Pages 249-254

  Wang, Pin ^a   Xie, Keqin ^b   Wang, Cunfu ^a   Bi, Jianzhong ^a  

^a Shandong University   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

MDA; Methylprednisolone; Oxidative stress; ROS; RRMS; TAC

Indexed keywords

BIOLOGICAL MARKER; GLUTATHIONE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; METHYLPREDNISOLONE; MYELOPEROXIDASE; PREDNISONE; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; CHOLESTEROL;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CEREBROSPINAL FLUID ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DEMYELINATION; DISEASE SEVERITY; DRUG DOSE REDUCTION; FEMALE; HUMAN; INFLAMMATION; LIPID PEROXIDATION; MALE; MULTIPLE SCLEROSIS; NERVE DEGENERATION; NORMOTENSIVE HYDROCEPHALUS; OXIDATIVE STRESS; PATHOGENESIS; POST HOC ANALYSIS; ANALYSIS OF VARIANCE; BLOOD; CEREBROSPINAL FLUID; COMPLICATION; DISABILITY; METABOLISM; MIDDLE AGED; NEURODEGENERATIVE DISEASES; PHYSIOLOGY;

ADULT; AGED; ANALYSIS OF VARIANCE; ANTIOXIDANTS; CHOLESTEROL; DISABILITY EVALUATION; GLUTATHIONE; HUMANS; LIPID PEROXIDATION; METHYLPREDNISOLONE; MIDDLE AGED; MULTIPLE SCLEROSIS; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84910040404     PISSN: 00143022     EISSN: 14219913     Source Type: Journal    
DOI: 10.1159/000363515     Document Type: Article

References (27)

1. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH: Mechanisms underlying inflammation in neurodegeneration. Cell 2010; 140: 918-934.
2. Su KG, Banker G, Bourdette D, Forte M: Axonal degeneration in multiple sclerosis: the mitochondrial hypothesis. Curr Neurol Neurosci Rep 2009; 9: 411-417.
3. Uttara B, Singh AV, Zamboni P, Mahajan RT: Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options. Curr Neuropharmacol 2009; 7: 65-74.
4. Miller E, Mrowicka M, Malinowska K, Zolynski K, Kedziora J: Effects of the wholebody cryotherapy on a total antioxidative status and activities of some antioxidative enzymes in blood of patients with multiple sclerosis - preliminary study. J Med Invest 2010; 57: 168-173.
5. van Horssen J, Witte ME, Schreibelt G, de Vries HE: Radical changes in multiple sclerosis pathogenesis. Biochim Biophys Acta 2011; 1812: 141-150.
6. Ghabaee M, Jabedari B, Al EEN, Ghaffarpour M, Asadi F: Serum and cerebrospinal fluid antioxidant activity and lipid peroxidation in Guillain-Barre syndrome and multiple sclerosis patients. Int J Neurosci 2010; 120: 301-304.
7. Witherick J, Wilkins A, Scolding N, Kemp K: Mechanisms of oxidative damage in multiple sclerosis and a cell therapy approach to treatment. Autoimmune Dis 2010; 2011: 164608.
8. Dringen R: Oxidative and antioxidative potential of brain microglial cells. Antioxid Redox Signal 2005; 7: 1223-1233.
9. Haider L, Fischer MT, Frischer JM, Bauer J, Höftberger R, Botond G, et al: Oxidative damage in multiple sclerosis lesions. Brain 2011; 134: 1914-1924.
10. Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H: The relation between inflammation and neurodegeneration in multiple sclerosis brains. Brain 2009; 132: 1175-1189.
11. Giovannoni G, Miller DH, Losseff NA, Sailer M, Lewellyn-Smith N, Thompson AJ, Thompson EJ: Serum inflammatory markers and clinical/ MRI markers of disease progression in multiple sclerosis. J Neurol 2001; 248: 487-495.
12. Mattsson N, Haghighi S, Andersen O, Yao Y, Rosengren L, Blennow K, Praticò D, Zetterberg H: Elevated cerebrospinal fluid F2-isoprostane levels indicating oxidative stress in healthy siblings of multiple sclerosis patients. Neurosci Lett 2007; 414: 233-236.
13. Mitosek-Szewczyk K, Gordon-Krajcer W, Walendzik P, Stelmasiak Z: Free radical peroxidation products in cerebrospinal fluid and serum of patients with multiple sclerosis after glucocorticoid therapy. Folia Neuropathol 2010; 48: 116-122.
14. McDonald WI, Compston A, Edan G, Goodkin D, Hartung HP, Lublin FD, McFarland HF, Paty DW, Polman CH, Reingold SC, Sandberg-Wollheim M, Sibley W, Thompson A, Van Den Noort S, Weinshenker BY, Wolinsky JS: Recommended diagnostic criteria for multiple sclerosis: guidelines from the international panel on the diagnosis of multiple sclerosis. Ann Neurol 2001; 50: 121-127.
15. Lublin FD, Reingold SC: Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on Clinical Trials of New Agents in Multiple Sclerosis. Neurology 1996; 46: 907-911.
16. Kurtzke JF: Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983; 33: 1444-1452.
17. Hoy A, Leininger-Müller B, Kutter D, Siest G, Visvikis S: Growing significance of myeloperoxidase in non-infectious diseases. Clin Chem Lab Med 2002;40:2-8 .
18. Floyd RA, Carney JM: Free radical damage to protein and DNA: mechanisms involved and relevant observations on brain undergoing oxidative stress. Ann Neurol 1992; 32:S22-S27.
19. Coyle JT, Puttfarcken P: Oxidative stress, glutamate, and neurodegenerative disorders. Science 1993; 262: 689-695.
20. Hemnani T, Parihar MS: Reactive oxygen species and oxidative DNA damage. Indian J Physiol Pharmacol 1998; 42: 440-452.
21. Casado A, de Lucas García N, López-Fernández ME, Rodríguez-Manzaneque AS, Fraile JAJ: Antioxidant enzymes, occupational stress and burnout in workers of a prehospitalary emergency service. Eur J Emerg Med 2005; 12: 111-115.
22. Casado A, de Lucas N, López-Fernández ME, Sánchez A, Jiménez JA: Lipid peroxidation, occupational stress and aging in workers of a prehospital emergency service. Eur J Emerg Med 2006; 133: 164-171.
23. Casado A, Castellanos A, López-Fernández ME, RocíoRuíz R, Aroca CG, Noriega F: Relationship between oxidative and occupational stress and aging in nurses of an intensive care unit. Age (Dordr) 2008; 30: 229-236.
24. Tunez I, Sanchez-Lopez F, Aguera E, Fernandez- Bolanos R, Sanchez FM, Tasset-Cuevas I: Important role of oxidative stress biomarkers in Huntington's disease. J Med Chem 2011; 54: 5602-5606.
25. Farooqui T, Farooqui AA: Lipid-mediated oxidative stress and inflammation in the pathogenesis of Parkinson's disease. Parkinsons Dis 2011; 2011: 247467.
26. Nagra RM, et al: Immunohistochemical and genetic evidence of myeloperoxidase involvement in multiple sclerosis. J Neuroimmunol 1997; 78: 97-107.
27. Gray E, Thomas TL, Betmouni S, Scolding N, Love S: Elevated myeloperoxidase activity in white matter in multiple sclerosis. Neurosci Lett 2008; 444: 195-198.