The environment of the lipoxygenase iron binding site explored with novel hydroxypyridinone iron chelators

Journal of Biological Chemistry

Volumn 271, Issue 14, 1996, Pages 7965-7972

  Abeysinghe, Rajeewa D ^a,c   Roberts, Pamela J ^a   Cooper, Chris E ^a   MacLean, Kirsteen H ^a   Hider, Robert C ^b   Porter, John B ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c Michigan State University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 QUINOLINOL; ARACHIDONIC ACID; CHELATING AGENT; DEFEROXAMINE; ICOSANOID; IRON; LIPOXYGENASE; LIPOXYGENASE INHIBITOR; PHOSPHOLIPASE A2; PIRIPROST; PYRIDONE DERIVATIVE; TRITIUM; TROPOLONE;

ARACHIDONIC ACID METABOLISM; ARTICLE; BINDING SITE; ELECTRON SPIN RESONANCE; ENZYME ACTIVATION; ENZYME INHIBITION; FATTY ACID METABOLISM; HUMAN; HUMAN CELL; HYDROPHILICITY; IRON CHELATION; LIPID OXIDATION; LIPOPHILICITY; NEUTROPHIL; PRIORITY JOURNAL; SOYBEAN;

ELECTRON SPIN RESONANCE SPECTROSCOPY; HUMANS; IRON; IRON CHELATING AGENTS; LIGANDS; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; NEUTROPHILS; PHOSPHOLIPASES A; PYRIDONES; SOLUBILITY; SOYBEANS; SUPEROXIDES;

GLYCINE MAX; TRITIUM;

EID: 0029887959     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.14.7965     Document Type: Article

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