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Volumn 2, Issue 7, 2017, Pages

Inhibition of neuronal ferroptosis protects hemorrhagic brain

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[No Author keywords available]

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EID: 85056460634     PISSN: None     EISSN: 23793708     Source Type: Journal    
DOI: 10.1172/jci.insight.90777     Document Type: Article
Times cited : (526)

References (79)
  • 1
    • 76249134436 scopus 로고    scopus 로고
    • Intracerebral haemorrhage: a need for more data and new research directions
    • Donnan GA, Hankey GJ, Davis SM. Intracerebral haemorrhage: a need for more data and new research directions. Lancet Neurol. 2010;9(2):133–134.
    • (2010) Lancet Neurol , vol.9 , Issue.2 , pp. 133-134
    • Donnan, GA1    Hankey, GJ2    Davis, SM.3
  • 2
    • 77956545744 scopus 로고    scopus 로고
    • Preclinical and clinical research on inflammation after intracerebral hemorrhage
    • Wang J. Preclinical and clinical research on inflammation after intracerebral hemorrhage. Prog Neurobiol. 2010;92(4):463–477.
    • (2010) Prog Neurobiol , vol.92 , Issue.4 , pp. 463-477
    • Wang, J.1
  • 3
    • 34247488271 scopus 로고    scopus 로고
    • Inflammation after intracerebral hemorrhage
    • Wang J, Dore S. Inflammation after intracerebral hemorrhage. J Cereb Blood Flow Metab. 2007;27(5):894–908.
    • (2007) J Cereb Blood Flow Metab , vol.27 , Issue.5 , pp. 894-908
    • Wang, J1    Dore, S.2
  • 4
    • 33846849030 scopus 로고    scopus 로고
    • Neuron death and inflammation in a rat model of intracerebral hemorrhage: effects of delayed minocycline treatment
    • Wasserman JK, Schlichter LC. Neuron death and inflammation in a rat model of intracerebral hemorrhage: effects of delayed minocycline treatment. Brain Res. 2007;1136(1):208–218.
    • (2007) Brain Res , vol.1136 , Issue.1 , pp. 208-218
    • Wasserman, JK1    Schlichter, LC.2
  • 5
    • 29044441975 scopus 로고    scopus 로고
    • Mechanisms of brain injury after intracerebral haemorrhage
    • Xi G, Keep RF, Hoff JT. Mechanisms of brain injury after intracerebral haemorrhage. Lancet Neurol. 2006;5(1):53–63.
    • (2006) Lancet Neurol , vol.5 , Issue.1 , pp. 53-63
    • Xi, G1    Keep, RF2    Hoff, JT.3
  • 6
    • 59449093578 scopus 로고    scopus 로고
    • The relationship between hematoma iron content and perihematoma edema: an MRI study
    • Lou M, Lieb K, Selim M. The relationship between hematoma iron content and perihematoma edema: an MRI study. Cerebrovasc Dis. 2009;27(3):266–271.
    • (2009) Cerebrovasc Dis , vol.27 , Issue.3 , pp. 266-271
    • Lou, M1    Lieb, K2    Selim, M.3
  • 7
    • 84886731334 scopus 로고    scopus 로고
    • Progress in translational research on intracerebral hemorrhage: is there an end in sight?
    • Xi G, Strahle J, Hua Y, Keep RF. Progress in translational research on intracerebral hemorrhage: is there an end in sight? Prog Neurobiol. 2014;115:45–63.
    • (2014) Prog Neurobiol , vol.115 , pp. 45-63
    • Xi, G1    Strahle, J2    Hua, Y3    Keep, RF.4
  • 8
    • 84890412095 scopus 로고    scopus 로고
    • Iron and intracerebral hemorrhage: from mechanism to translation
    • Xiong XY, Wang J, Qian ZM, Yang QW. Iron and intracerebral hemorrhage: from mechanism to translation. Transl Stroke Res. 2014;5(4):429–441.
    • (2014) Transl Stroke Res , vol.5 , Issue.4 , pp. 429-441
    • Xiong, XY1    Wang, J2    Qian, ZM3    Yang, QW.4
  • 10
    • 77951137998 scopus 로고    scopus 로고
    • Iron in neuronal function and dysfunction
    • Salvador GA. Iron in neuronal function and dysfunction. Biofactors. 2010;36(2):103–110.
    • (2010) Biofactors , vol.36 , Issue.2 , pp. 103-110
    • Salvador, GA.1
  • 11
    • 58149123408 scopus 로고    scopus 로고
    • Role of iron in neurotoxicity: a cause for concern in the elderly?
    • Stankiewicz JM, Brass SD. Role of iron in neurotoxicity: a cause for concern in the elderly? Curr Opin Clin Nutr Metab Care. 2009;12(1):22–29.
    • (2009) Curr Opin Clin Nutr Metab Care , vol.12 , Issue.1 , pp. 22-29
    • Stankiewicz, JM1    Brass, SD.2
  • 12
    • 34249305881 scopus 로고    scopus 로고
    • Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cells
    • Gaasch JA, Lockman PR, Geldenhuys WJ, Allen DD, Van der Schyf CJ. Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cells. Neurochem Res. 2007;32(7):1196–1208.
    • (2007) Neurochem Res , vol.32 , Issue.7 , pp. 1196-1208
    • Gaasch, JA1    Lockman, PR2    Geldenhuys, WJ3    Allen, DD4    Van der Schyf, CJ.5
  • 13
    • 62949225543 scopus 로고    scopus 로고
    • Deferoxamine mesylate: a new hope for intracerebral hemorrhage: from bench to clinical trials
    • (Suppl)
    • Selim M. Deferoxamine mesylate: a new hope for intracerebral hemorrhage: from bench to clinical trials. Stroke. 2009;40(3 Suppl):S90–S91.
    • (2009) Stroke , vol.40 , Issue.3 , pp. S90-S91
    • Selim, M.1
  • 14
    • 0033622126 scopus 로고    scopus 로고
    • Evidence for apoptosis after intercerebral hemorrhage in rat striatum
    • Matsushita K, et al. Evidence for apoptosis after intercerebral hemorrhage in rat striatum. J Cereb Blood Flow Metab. 2000;20(2):396–404.
    • (2000) J Cereb Blood Flow Metab , vol.20 , Issue.2 , pp. 396-404
    • Matsushita, K1
  • 15
    • 0037407116 scopus 로고    scopus 로고
    • Apoptosis as a form of cell death in intracerebral hemorrhage
    • discussion 1047–1048
    • Qureshi AI, et al. Apoptosis as a form of cell death in intracerebral hemorrhage. Neurosurgery. 2003;52(5):1041–1047; discussion 1047–1048.
    • (2003) Neurosurgery , vol.52 , Issue.5 , pp. 1041-1047
    • Qureshi, AI1
  • 16
    • 0035057206 scopus 로고    scopus 로고
    • Intracerebral hemorrhage-induced neuronal death
    • discussion 882
    • Gong C, Boulis N, Qian J, Turner DE, Hoff JT, Keep RF. Intracerebral hemorrhage-induced neuronal death. Neurosurgery. 2001;48(4):875–882; discussion 882.
    • (2001) Neurosurgery , vol.48 , Issue.4 , pp. 875-882
    • Gong, C1    Boulis, N2    Qian, J3    Turner, DE4    Hoff, JT5    Keep, RF.6
  • 17
    • 41149156985 scopus 로고    scopus 로고
    • Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse
    • Grossetete M, Rosenberg GA. Matrix metalloproteinase inhibition facilitates cell death in intracerebral hemorrhage in mouse. J Cereb Blood Flow Metab. 2008;28(4):752–763.
    • (2008) J Cereb Blood Flow Metab , vol.28 , Issue.4 , pp. 752-763
    • Grossetete, M1    Rosenberg, GA.2
  • 18
    • 84875309392 scopus 로고    scopus 로고
    • The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation
    • Serrano L, et al. The tumor suppressor SirT2 regulates cell cycle progression and genome stability by modulating the mitotic deposition of H4K20 methylation. Genes Dev. 2013;27(6):639–653.
    • (2013) Genes Dev , vol.27 , Issue.6 , pp. 639-653
    • Serrano, L1
  • 19
    • 84856455125 scopus 로고    scopus 로고
    • Plasmalemma permeability and necrotic cell death phenotypes after intracerebral hemorrhage in mice
    • Zhu X, et al. Plasmalemma permeability and necrotic cell death phenotypes after intracerebral hemorrhage in mice. Stroke. 2012;43(2):524–531.
    • (2012) Stroke , vol.43 , Issue.2 , pp. 524-531
    • Zhu, X1
  • 20
    • 42549126839 scopus 로고    scopus 로고
    • Autophagy after experimental intracerebral hemorrhage
    • He Y, Wan S, Hua Y, Keep RF, Xi G. Autophagy after experimental intracerebral hemorrhage. J Cereb Blood Flow Metab. 2008;28(5):897–905.
    • (2008) J Cereb Blood Flow Metab , vol.28 , Issue.5 , pp. 897-905
    • He, Y1    Wan, S2    Hua, Y3    Keep, RF4    Xi, G.5
  • 21
    • 84867250358 scopus 로고    scopus 로고
    • Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage
    • Chen CW, et al. Inhibition of autophagy as a therapeutic strategy of iron-induced brain injury after hemorrhage. Autophagy. 2012;8(10):1510–1520.
    • (2012) Autophagy , vol.8 , Issue.10 , pp. 1510-1520
    • Chen, CW1
  • 22
    • 0036318246 scopus 로고    scopus 로고
    • Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress
    • Wang X, Mori T, Sumii T, Lo EH. Hemoglobin-induced cytotoxicity in rat cerebral cortical neurons: caspase activation and oxidative stress. Stroke. 2002;33(7):1882–1888.
    • (2002) Stroke , vol.33 , Issue.7 , pp. 1882-1888
    • Wang, X1    Mori, T2    Sumii, T3    Lo, EH.4
  • 23
    • 77952911671 scopus 로고    scopus 로고
    • Exploring the optimal operation time for patients with hypertensive intracerebral hemorrhage: tracking the expression and progress of cell apoptosis of prehematomal brain tissues
    • Zhang XQ, Zhang ZM, Yin XL, Zhang K, Cai H, Ling F. Exploring the optimal operation time for patients with hypertensive intracerebral hemorrhage: tracking the expression and progress of cell apoptosis of prehematomal brain tissues. Chin Med J (Engl). 2010;123(10):1246–1250.
    • (2010) Chin Med J (Engl) , vol.123 , Issue.10 , pp. 1246-1250
    • Zhang, XQ1    Zhang, ZM2    Yin, XL3    Zhang, K4    Cai, H5    Ling, F.6
  • 24
    • 84958103915 scopus 로고    scopus 로고
    • Ferroptosis: Death by lipid peroxidation
    • Yang WS, Stockwell BR. Ferroptosis: Death by lipid peroxidation. Trends Cell Biol. 2016;26(3):165–176.
    • (2016) Trends Cell Biol , vol.26 , Issue.3 , pp. 165-176
    • Yang, WS1    Stockwell, BR.2
  • 25
    • 84926387317 scopus 로고    scopus 로고
    • Ferroptosis as a p53-mediated activity during tumour suppression
    • Jiang L, et al. Ferroptosis as a p53-mediated activity during tumour suppression. Nature. 2015;520(7545):57–62.
    • (2015) Nature , vol.520 , Issue.7545 , pp. 57-62
    • Jiang, L1
  • 26
    • 84861541814 scopus 로고    scopus 로고
    • Ferroptosis: an iron-dependent form of nonapoptotic cell death
    • Dixon SJ, et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell. 2012;149(5):1060–1072.
    • (2012) Cell , vol.149 , Issue.5 , pp. 1060-1072
    • Dixon, SJ1
  • 27
    • 84937525519 scopus 로고    scopus 로고
    • Glutaminolysis and transferrin regulate ferroptosis
    • Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and transferrin regulate ferroptosis. Mol Cell. 2015;59(2):298–308.
    • (2015) Mol Cell , vol.59 , Issue.2 , pp. 298-308
    • Gao, M1    Monian, P2    Quadri, N3    Ramasamy, R4    Jiang, X.5
  • 28
    • 84892685001 scopus 로고    scopus 로고
    • Regulation of ferroptotic cancer cell death by GPX4
    • Yang WS, et al. Regulation of ferroptotic cancer cell death by GPX4. Cell. 2014;156(1–2):317–331.
    • (2014) Cell , vol.156 , Issue.1–2 , pp. 317-331
    • Yang, WS1
  • 29
    • 85042679104 scopus 로고    scopus 로고
    • Glutathione peroxidase 4 (Gpx4) and ferroptosis: what’s so special about it?
    • Conrad M, Friedmann Angeli JP. Glutathione peroxidase 4 (Gpx4) and ferroptosis: what’s so special about it? Mol Cell Oncol. 2015;2(3):e995047.
    • (2015) Mol Cell Oncol , vol.2 , Issue.3 , pp. e995047
    • Conrad, M1    Friedmann Angeli, JP.2
  • 30
    • 79952322458 scopus 로고    scopus 로고
    • Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain
    • Wu T, Wu H, Wang J, Wang J. Expression and cellular localization of cyclooxygenases and prostaglandin E synthases in the hemorrhagic brain. J Neuroinflammation. 2011;8:22.
    • (2011) J Neuroinflammation , vol.8 , pp. 22
    • Wu, T1    Wu, H2    Wang, J3    Wang, J.4
  • 31
    • 3843082003 scopus 로고    scopus 로고
    • Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death
    • Chu K, et al. Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. J Cereb Blood Flow Metab. 2004;24(8):926–933.
    • (2004) J Cereb Blood Flow Metab , vol.24 , Issue.8 , pp. 926-933
    • Chu, K1
  • 32
    • 77957660973 scopus 로고    scopus 로고
    • 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases
    • Conrad M, et al. 12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases. Proc Natl Acad Sci U S A. 2010;107(36):15774–15779.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , Issue.36 , pp. 15774-15779
    • Conrad, M1
  • 33
    • 84902581565 scopus 로고    scopus 로고
    • (-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways
    • Chang CF, Cho S, Wang J. (-)-Epicatechin protects hemorrhagic brain via synergistic Nrf2 pathways. Ann Clin Transl Neurol. 2014;1(4):258–271.
    • (2014) Ann Clin Transl Neurol , vol.1 , Issue.4 , pp. 258-271
    • Chang, CF1    Cho, S2    Wang, J.3
  • 34
    • 84913582286 scopus 로고    scopus 로고
    • Synchronized renal tubular cell death involves ferroptosis
    • Linkermann A, et al. Synchronized renal tubular cell death involves ferroptosis. Proc Natl Acad Sci U S A. 2014;111(47):16836–16841.
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.47 , pp. 16836-16841
    • Linkermann, A1
  • 35
  • 36
    • 84925286831 scopus 로고    scopus 로고
    • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
    • Friedmann Angeli JP, et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol. 2014;16(12):1180–1191.
    • (2014) Nat Cell Biol , vol.16 , Issue.12 , pp. 1180-1191
    • Friedmann Angeli, JP1
  • 37
    • 84978481313 scopus 로고    scopus 로고
    • Ferroptosis, a newly characterized form of cell death in Parkinson’s disease that is regulated by PKC
    • Do Van B, et al. Ferroptosis, a newly characterized form of cell death in Parkinson’s disease that is regulated by PKC. Neurobiol Dis. 2016;94:169–178.
    • (2016) Neurobiol Dis , vol.94 , pp. 169-178
    • Do Van, B1
  • 38
    • 77956501969 scopus 로고    scopus 로고
    • Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo
    • Katsu M, Niizuma K, Yoshioka H, Okami N, Sakata H, Chan PH. Hemoglobin-induced oxidative stress contributes to matrix metalloproteinase activation and blood-brain barrier dysfunction in vivo. J Cereb Blood Flow Metab. 2010;30(12):1939–1950.
    • (2010) J Cereb Blood Flow Metab , vol.30 , Issue.12 , pp. 1939-1950
    • Katsu, M1    Niizuma, K2    Yoshioka, H3    Okami, N4    Sakata, H5    Chan, PH.6
  • 39
    • 84957104695 scopus 로고    scopus 로고
    • Oxidative stress in intracerebral hemorrhage: sources, mechanisms, and therapeutic targets
    • Hu X, Tao C, Gan Q, Zheng J, Li H, You C. Oxidative stress in intracerebral hemorrhage: sources, mechanisms, and therapeutic targets. Oxid Med Cell Longev. 2016;2016:3215391.
    • (2016) Oxid Med Cell Longev , vol.2016 , pp. 3215391
    • Hu, X1    Tao, C2    Gan, Q3    Zheng, J4    Li, H5    You, C.6
  • 40
    • 84903200586 scopus 로고    scopus 로고
    • Blood-brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation
    • Ding R, et al. Blood-brain barrier disruption induced by hemoglobin in vivo: Involvement of up-regulation of nitric oxide synthase and peroxynitrite formation. Brain Res. 2014;1571:25–38.
    • (2014) Brain Res , vol.1571 , pp. 25-38
    • Ding, R1
  • 41
    • 84875230010 scopus 로고    scopus 로고
    • Role of iron in brain lipocalin 2 upregulation after intracerebral hemorrhage in rats
    • Dong M, Xi G, Keep RF, Hua Y. Role of iron in brain lipocalin 2 upregulation after intracerebral hemorrhage in rats. Brain Res. 2013;1505:86–92.
    • (2013) Brain Res , vol.1505 , pp. 86-92
    • Dong, M1    Xi, G2    Keep, RF3    Hua, Y.4
  • 42
    • 47149093139 scopus 로고    scopus 로고
    • Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin
    • Regan RF, Chen M, Li Z, Zhang X, Benvenisti-Zarom L, Chen-Roetling J. Neurons lacking iron regulatory protein-2 are highly resistant to the toxicity of hemoglobin. Neurobiol Dis. 2008;31(2):242–249.
    • (2008) Neurobiol Dis , vol.31 , Issue.2 , pp. 242-249
    • Regan, RF1    Chen, M2    Li, Z3    Zhang, X4    Benvenisti-Zarom, L5    Chen-Roetling, J.6
  • 43
    • 77952544962 scopus 로고    scopus 로고
    • Iron regulatory protein-2 knockout increases perihematomal ferritin expression and cell viability after intracerebral hemorrhage
    • Chen M, Awe OO, Chen-Roetling J, Regan RF. Iron regulatory protein-2 knockout increases perihematomal ferritin expression and cell viability after intracerebral hemorrhage. Brain Res. 2010;1337:95–103.
    • (2010) Brain Res , vol.1337 , pp. 95-103
    • Chen, M1    Awe, OO2    Chen-Roetling, J3    Regan, RF.4
  • 44
    • 84908028367 scopus 로고    scopus 로고
    • TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord
    • Kroner A, Greenhalgh AD, Zarruk JG, Passos Dos Santos R, Gaestel M, David S. TNF and increased intracellular iron alter macrophage polarization to a detrimental M1 phenotype in the injured spinal cord. Neuron. 2014;83(5):1098–1116.
    • (2014) Neuron , vol.83 , Issue.5 , pp. 1098-1116
    • Kroner, A1    Greenhalgh, AD2    Zarruk, JG3    Passos Dos Santos, R4    Gaestel, M5    David, S.6
  • 45
    • 84920717602 scopus 로고    scopus 로고
    • Microglial and macrophage polarization-new prospects for brain repair
    • Hu X, et al. Microglial and macrophage polarization-new prospects for brain repair. Nat Rev Neurol. 2015;11(1):56–64.
    • (2015) Nat Rev Neurol , vol.11 , Issue.1 , pp. 56-64
    • Hu, X1
  • 46
    • 0033969034 scopus 로고    scopus 로고
    • Effects of hypoxia and glutathione depletion on hemoglobin- and myoglobin-mediated oxidative stress toward endothelium
    • D’Agnillo F, Wood F, Porras C, Macdonald VW, Alayash AI. Effects of hypoxia and glutathione depletion on hemoglobin- and myoglobin-mediated oxidative stress toward endothelium. Biochim Biophys Acta. 2000;1495(2):150–159.
    • (2000) Biochim Biophys Acta , vol.1495 , Issue.2 , pp. 150-159
    • D’Agnillo, F1    Wood, F2    Porras, C3    Macdonald, VW4    Alayash, AI.5
  • 47
    • 53049083456 scopus 로고    scopus 로고
    • Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes
    • Laird MD, Wakade C, Alleyne CH, Dhandapani KM. Hemin-induced necroptosis involves glutathione depletion in mouse astrocytes. Free Radic Biol Med. 2008;45(8):1103–1114.
    • (2008) Free Radic Biol Med , vol.45 , Issue.8 , pp. 1103-1114
    • Laird, MD1    Wakade, C2    Alleyne, CH3    Dhandapani, KM.4
  • 48
    • 84887273465 scopus 로고    scopus 로고
    • Perihematomal glutamate level is associated with the blood-brain barrier disruption in a rabbit model of intracerebral hemorrhage
    • Wu G, Sun S, Sheng F, Wang L, Wang F. Perihematomal glutamate level is associated with the blood-brain barrier disruption in a rabbit model of intracerebral hemorrhage. Springerplus. 2013;2:358.
    • (2013) Springerplus , vol.2 , pp. 358
    • Wu, G1    Sun, S2    Sheng, F3    Wang, L4    Wang, F.5
  • 49
    • 0037176898 scopus 로고    scopus 로고
    • Molecular signatures of brain injury after intracerebral hemorrhage
    • Castillo J, et al. Molecular signatures of brain injury after intracerebral hemorrhage. Neurology. 2002;58(4):624–629.
    • (2002) Neurology , vol.58 , Issue.4 , pp. 624-629
    • Castillo, J1
  • 50
    • 80054026965 scopus 로고    scopus 로고
    • Comparison of humoral neuroinflammation and adhesion molecule expression in two models of experimental intracerebral hemorrhage
    • Liesz A, Middelhoff M, Zhou W, Karcher S, Illanes S, Veltkamp R. Comparison of humoral neuroinflammation and adhesion molecule expression in two models of experimental intracerebral hemorrhage. Exp Transl Stroke Med. 2011;3(1):11.
    • (2011) Exp Transl Stroke Med , vol.3 , Issue.1 , pp. 11
    • Liesz, A1    Middelhoff, M2    Zhou, W3    Karcher, S4    Illanes, S5    Veltkamp, R.6
  • 51
    • 84862268309 scopus 로고    scopus 로고
    • Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats
    • (Suppl 1)
    • Lively S, Schlichter LC. Age-related comparisons of evolution of the inflammatory response after intracerebral hemorrhage in rats. Transl Stroke Res. 2012;3(Suppl 1):132–146.
    • (2012) Transl Stroke Res , vol.3 , pp. 132-146
    • Lively, S1    Schlichter, LC.2
  • 52
    • 0036735698 scopus 로고    scopus 로고
    • Human brain hemorrhage: quantification of perihematoma edema by use of diffusion-weighted MR imaging
    • Carhuapoma JR, Barker PB, Hanley DF, Wang P, Beauchamp NJ. Human brain hemorrhage: quantification of perihematoma edema by use of diffusion-weighted MR imaging. AJNR Am J Neuroradiol. 2002;23(8):1322–1326.
    • (2002) AJNR Am J Neuroradiol , vol.23 , Issue.8 , pp. 1322-1326
    • Carhuapoma, JR1    Barker, PB2    Hanley, DF3    Wang, P4    Beauchamp, NJ.5
  • 53
    • 84901695723 scopus 로고    scopus 로고
    • Histological, cellular and behavioral assessments of stroke outcomes after photothrombosis-induced ischemia in adult mice
    • Li H, et al. Histological, cellular and behavioral assessments of stroke outcomes after photothrombosis-induced ischemia in adult mice. BMC Neurosci. 2014;15:58.
    • (2014) BMC Neurosci , vol.15 , pp. 58
    • Li, H1
  • 54
    • 30344438523 scopus 로고    scopus 로고
    • Apoptosis dominant in the periinfarct area of human ischaemic stroke-a possible target of antiapoptotic treatments
    • (Pt 1)
    • Sairanen T, Karjalainen-Lindsberg ML, Paetau A, Ijas P, Lindsberg PJ. Apoptosis dominant in the periinfarct area of human ischaemic stroke-a possible target of antiapoptotic treatments. Brain. 2006;129(Pt 1):189–199.
    • (2006) Brain , vol.129 , pp. 189-199
    • Sairanen, T1    Karjalainen-Lindsberg, ML2    Paetau, A3    Ijas, P4    Lindsberg, PJ.5
  • 55
    • 84974587365 scopus 로고    scopus 로고
    • Ipsilateral and contralateral cortical apoptosis in rats after unilateral middle cerebral artery occlusion
    • Dief AEE, Jirikowski GF, Ragab KES, Ibrahim HS. Ipsilateral and contralateral cortical apoptosis in rats after unilateral middle cerebral artery occlusion. Anatomy. 2008;2:39–48.
    • (2008) Anatomy , vol.2 , pp. 39-48
    • Dief, AEE1    Jirikowski, GF2    Ragab, KES3    Ibrahim, HS.4
  • 56
    • 84976292806 scopus 로고    scopus 로고
    • Autophagy promotes ferroptosis by degradation of ferritin
    • Hou W, et al. Autophagy promotes ferroptosis by degradation of ferritin. Autophagy. 2016;12(8):1425–1428.
    • (2016) Autophagy , vol.12 , Issue.8 , pp. 1425-1428
    • Hou, W1
  • 57
    • 84896705528 scopus 로고    scopus 로고
    • Gender and age interact to affect early outcome after intracerebral hemorrhage
    • Umeano O, et al. Gender and age interact to affect early outcome after intracerebral hemorrhage. PLoS One. 2013;8(11):e81664.
    • (2013) PLoS One , vol.8 , Issue.11 , pp. e81664
    • Umeano, O1
  • 58
    • 84882678911 scopus 로고    scopus 로고
    • Differential regulation of cell death programs in males and females by poly (ADP-ribose) polymerase-1 and 17beta estradiol
    • Jog NR, Caricchio R. Differential regulation of cell death programs in males and females by poly (ADP-ribose) polymerase-1 and 17beta estradiol. Cell Death Dis. 2013;4:e758.
    • (2013) Cell Death Dis , vol.4 , pp. e758
    • Jog, NR1    Caricchio, R.2
  • 59
    • 84922244018 scopus 로고    scopus 로고
    • Gender differences in parameters of lipid metabolism and of level of antioxidants in groups of juveniles-the Evenks and the europeans
    • Kolesnikova LI, Darenskaya MA, Grebenkina LA, Dolgikh MI, Astakhova TA, Semenova NV. [Gender differences in parameters of lipid metabolism and of level of antioxidants in groups of juveniles-the Evenks and the europeans]. Zh Evol Biokhim Fiziol. 2014;50(1):31–37.
    • (2014) Zh Evol Biokhim Fiziol , vol.50 , Issue.1 , pp. 31-37
    • Kolesnikova, LI1    Darenskaya, MA2    Grebenkina, LA3    Dolgikh, MI4    Astakhova, TA5    Semenova, NV.6
  • 60
    • 80052564156 scopus 로고    scopus 로고
    • Testosterone or 17{beta}-estradiol exposure reveals sex-specific effects on glucose and lipid metabolism in human myotubes
    • Salehzadeh F, Rune A, Osler M, Al-Khalili L. Testosterone or 17{beta}-estradiol exposure reveals sex-specific effects on glucose and lipid metabolism in human myotubes. J Endocrinol. 2011;210(2):219–229.
    • (2011) J Endocrinol , vol.210 , Issue.2 , pp. 219-229
    • Salehzadeh, F1    Rune, A2    Osler, M3    Al-Khalili, L.4
  • 61
    • 0026099937 scopus 로고
    • Sex differences in postischemic neuronal necrosis in gerbils
    • Hall ED, Pazara KE, Linseman KL. Sex differences in postischemic neuronal necrosis in gerbils. J Cereb Blood Flow Metab. 1991;11(2):292–298.
    • (1991) J Cereb Blood Flow Metab , vol.11 , Issue.2 , pp. 292-298
    • Hall, ED1    Pazara, KE2    Linseman, KL.3
  • 62
    • 79959669623 scopus 로고    scopus 로고
    • Iron toxicity in mice with collagenase-induced intracerebral hemorrhage
    • Wu H, Wu T, Xu X, Wang J, Wang J. Iron toxicity in mice with collagenase-induced intracerebral hemorrhage. J Cereb Blood Flow Metab. 2011;31(5):1243–1250.
    • (2011) J Cereb Blood Flow Metab , vol.31 , Issue.5 , pp. 1243-1250
    • Wu, H1    Wu, T2    Xu, X3    Wang, J4    Wang, J.5
  • 63
    • 84877134982 scopus 로고    scopus 로고
    • RIGOR guidelines: escalating STAIR and STEPS for effective translational research
    • Lapchak PA, Zhang JH, Noble-Haeusslein LJ. RIGOR guidelines: escalating STAIR and STEPS for effective translational research. Transl Stroke Res. 2013;4(3):279–285.
    • (2013) Transl Stroke Res , vol.4 , Issue.3 , pp. 279-285
    • Lapchak, PA1    Zhang, JH2    Noble-Haeusslein, LJ.3
  • 64
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol. 2000;20(11):4106–4114.
    • (2000) Mol Cell Biol , vol.20 , Issue.11 , pp. 4106-4114
    • Jung, S1
  • 65
    • 46749109127 scopus 로고    scopus 로고
    • The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood
    • Wang J, Fields J, Dore S. The development of an improved preclinical mouse model of intracerebral hemorrhage using double infusion of autologous whole blood. Brain Res. 2008;1222:214–221.
    • (2008) Brain Res , vol.1222 , pp. 214-221
    • Wang, J1    Fields, J2    Dore, S.3
  • 66
    • 84928825586 scopus 로고    scopus 로고
    • Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice
    • Zhao X, et al. Toxic role of prostaglandin E2 receptor EP1 after intracerebral hemorrhage in mice. Brain Behav Immun. 2015;46:293–310.
    • (2015) Brain Behav Immun , vol.46 , pp. 293-310
    • Zhao, X1
  • 67
    • 0036945109 scopus 로고    scopus 로고
    • L-arginyl-3,4-spermidine is neuroprotective in several in vitro models of neurodegeneration and in vivo ischaemia without suppressing synaptic transmission
    • Morrison B, et al. L-arginyl-3,4-spermidine is neuroprotective in several in vitro models of neurodegeneration and in vivo ischaemia without suppressing synaptic transmission. Br J Pharmacol. 2002;137(8):1255–1268.
    • (2002) Br J Pharmacol , vol.137 , Issue.8 , pp. 1255-1268
    • Morrison, B1
  • 68
    • 84938489538 scopus 로고    scopus 로고
    • Organotypic hippocampal slices as models for stroke and traumatic brain injury
    • Li Q, Han X, Wang J. Organotypic hippocampal slices as models for stroke and traumatic brain injury. Mol Neurobiol. 2016;53(6):4226–4237.
    • (2016) Mol Neurobiol , vol.53 , Issue.6 , pp. 4226-4237
    • Li, Q1    Han, X2    Wang, J.3
  • 69
    • 84973340621 scopus 로고    scopus 로고
    • Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury
    • Han X, et al. Inhibition of prostaglandin E2 receptor EP3 mitigates thrombin-induced brain injury. J Cereb Blood Flow Metab. 2016;36(6):1059–1074.
    • (2016) J Cereb Blood Flow Metab , vol.36 , Issue.6 , pp. 1059-1074
    • Han, X1
  • 70
    • 84878849645 scopus 로고    scopus 로고
    • Rapid single-step induction of functional neurons from human pluripotent stem cells
    • Zhang Y, et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 2013;78(5):785–798.
    • (2013) Neuron , vol.78 , Issue.5 , pp. 785-798
    • Zhang, Y1
  • 71
    • 84905493178 scopus 로고    scopus 로고
    • Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons
    • Sagal J, et al. Proneural transcription factor Atoh1 drives highly efficient differentiation of human pluripotent stem cells into dopaminergic neurons. Stem Cells Transl Med. 2014;3(8):888–898.
    • (2014) Stem Cells Transl Med , vol.3 , Issue.8 , pp. 888-898
    • Sagal, J1
  • 72
    • 77956497712 scopus 로고    scopus 로고
    • Targeting mitochondrial glutaminase activity inhibits oncogenic transformation
    • Wang JB, et al. Targeting mitochondrial glutaminase activity inhibits oncogenic transformation. Cancer Cell. 2010;18(3):207–219.
    • (2010) Cancer Cell , vol.18 , Issue.3 , pp. 207-219
    • Wang, JB1
  • 73
    • 20144384669 scopus 로고    scopus 로고
    • Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfo-nyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors
    • Kravchenko DV, et al. Synthesis and structure-activity relationship of 4-substituted 2-(2-acetyloxyethyl)-8-(morpholine-4-sulfo-nyl)pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. J Med Chem. 2005;48(11):3680–3683.
    • (2005) J Med Chem , vol.48 , Issue.11 , pp. 3680-3683
    • Kravchenko, DV1
  • 74
    • 84932095487 scopus 로고    scopus 로고
    • Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis
    • Wu XN, et al. Distinct roles of RIP1-RIP3 hetero- and RIP3-RIP3 homo-interaction in mediating necroptosis. Cell Death Differ. 2014;21(11):1709–1720.
    • (2014) Cell Death Differ , vol.21 , Issue.11 , pp. 1709-1720
    • Wu, XN1
  • 75
    • 0005677775 scopus 로고
    • 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen PO, Gordon PB. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc Natl Acad Sci U S A. 1982;79(6):1889–1892.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , Issue.6 , pp. 1889-1892
    • Seglen, PO1    Gordon, PB.2
  • 76
    • 85006341577 scopus 로고    scopus 로고
    • Cerebroprotection by the neuronal PGE2 receptor EP2 after intracerebral hemorrhage in middle-aged mice
    • Wu H, et al. Cerebroprotection by the neuronal PGE2 receptor EP2 after intracerebral hemorrhage in middle-aged mice. J Cereb Blood Flow Metab. 2017;37(1):39–51.
    • (2017) J Cereb Blood Flow Metab , vol.37 , Issue.1 , pp. 39-51
    • Wu, H1
  • 77
    • 84923595111 scopus 로고    scopus 로고
    • PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice
    • Wu H, et al. PGE2 receptor agonist misoprostol protects brain against intracerebral hemorrhage in mice. Neurobiol Aging. 2015;36(3):1439–1450.
    • (2015) Neurobiol Aging , vol.36 , Issue.3 , pp. 1439-1450
    • Wu, H1
  • 78
    • 84885404060 scopus 로고    scopus 로고
    • Iron accumulates in Huntington’s disease neurons: protection by deferoxamine
    • Chen J, et al. Iron accumulates in Huntington’s disease neurons: protection by deferoxamine. PLoS One. 2013;8(10):e77023.
    • (2013) PLoS One , vol.8 , Issue.10 , pp. e77023
    • Chen, J1
  • 79
    • 84874744907 scopus 로고    scopus 로고
    • Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance
    • Zhou J, et al. Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance. PLoS One. 2013;8(3):e57503.
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e57503
    • Zhou, J1


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