Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death

Cell Metabolism

Volumn 8, Issue 3, 2008, Pages 237-248

  Seiler, Alexander ^a   Schneider, Manuela ^a   Förster, Heidi ^a   Roth, Stephan ^b   Wirth, Eva K ^b   Culmsee, Carsten ^c   Plesnila, Nikolaus ^d   Kremmer, Elisabeth ^e   Rådmark, Olof ^f   Wurst, Wolfgang ^e,g   Bornkamm, Georg W ^a   Schweizer, Ulrich ^b   Conrad, Marcus ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

^f KAROLINSKA INSTITUTE   (Sweden)

^g MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

HUMDISEASE; SIGNALING

Indexed keywords

ALPHA TOCOPHEROL; APOPTOSIS INDUCING FACTOR; ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLUTATHIONE; GLUTATHIONE PEROXIDASE; LIPID; LIPOXYGENASE INHIBITOR; OXYGEN RADICAL; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL SPECIFICITY; CONTROLLED STUDY; DRUG TARGETING; EMBRYO; ENZYME DEFICIENCY; ENZYME INACTIVATION; ENZYME INDUCTION; EX VIVO STUDY; GENE SILENCING; IN VIVO STUDY; KNOCKOUT MOUSE; LIPID PEROXIDATION; MEDICAL RESEARCH; MOLECULAR MECHANICS; MOUSE; NERVE CELL; NERVE DEGENERATION; NEWBORN; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RNA INTERFERENCE;

ALLELES; ALPHA-TOCOPHEROL; ANIMALS; APOPTOSIS INDUCING FACTOR; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; CELL DEATH; CELLS, CULTURED; FLUORENES; GENOTYPE; GLUTATHIONE PEROXIDASE; HIPPOCAMPUS; HUMANS; LIPID PEROXIDATION; MICE; MICE, CONGENIC; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING;

MUS;

EID: 50049133588     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2008.07.005     Document Type: Article

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