Regulation of ferroptotic cancer cell death by GPX4

Cell

Volumn 156, Issue 1-2, 2014, Pages 317-331

  Yang, Wan Seok ^a   Sriramaratnam, Rohitha ^a   Welsch, Matthew E ^a   Shimada, Kenichi ^a   Skouta, Rachid ^a   Viswanathan, Vasanthi S ^a,b   Cheah, Jaime H ^b   Clemons, Paul A ^b   Shamji, Alykhan F ^b   Clish, Clary B ^b   Brown, Lewis M ^a   Girotti, Albert W ^c   Cornish, Virginia W ^a   Schreiber, Stuart L ^b   Stockwell, Brent R ^a,d  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; ANTINEOPLASTIC AGENT; CYCLOOXYGENASE 2; DOXORUBICIN; GLUTATHIONE; MESSENGER RNA; PIPERAZINE DERIVATIVE; PIPERAZINE ERASTIN; RSL3; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER INHIBITION; CELL DEATH; ENZYME INACTIVATION; FERROPTOSIS; KIDNEY CARCINOMA; LARGE CELL LYMPHOMA; METABOLOMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; REGULATORY MECHANISM; SENSITIVITY ANALYSIS; TUMOR XENOGRAFT; ANIMAL TISSUE; CELL VIABILITY; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVITY; ESSENTIAL GENE; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; LIPID PEROXIDATION; PROTEIN DEPLETION; RNA INTERFERENCE; STEREOCHEMISTRY; TUMOR GROWTH; TUMOR VOLUME;

ANIMALS; CARBOLINES; CARCINOMA, RENAL CELL; CELL DEATH; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HETEROGRAFTS; HUMANS; LYMPHOMA, B-CELL; MICE; NEOPLASM TRANSPLANTATION; NEOPLASMS; PIPERAZINES;

EID: 84892685001     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.12.010     Document Type: Article

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