Production and Extraction of Polysaccharides and Oligosaccharides and Their Use as New Food Additives

Industrial Biorefineries and White Biotechnology

Volumn , Issue , 2015, Pages 653-679

  Nobre, Clarisse ^a   Cerqueira, Miguel Ângelo ^a   Rodrigues, Lígia Raquel ^a   Vicente, António Augusto ^a   Teixeira, José António ^a  

^a UNIVERSITY OF MINHO   (Portugal)

Author keywords

Carbohydrates; Functional; Hydrocolloids; Oligosaccharides; Polysaccharides; Prebiotics

Indexed keywords

CARBOHYDRATES; COMMERCE; EMULSIFICATION; NUTRITION; OLIGOSACCHARIDES; POLYSACCHARIDES; TEXTURES;

COMMERCIAL PRODUCTS; COMPOUND ANNUAL GROWTH RATES; FUNCTIONAL; HYDROCOLLOIDS; NATURAL POLYSACCHARIDE; NUTRITIONAL BENEFITS; PREBIOTICS; SCIENTIFIC COMMUNITY;

FOOD ADDITIVES;

EID: 85031778181     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-444-63453-5.00021-5     Document Type: Chapter

References (199)

1. FAO Carbohydrates in human nutrition 1998, FAO Food and Nutrition Papers, (acceded in 18.03.2014). http://www.fao.org/docrep/w8079E/w8079e07.htm#TopOfPage
2. Williams P.A., Phillips G.O. Introduction to food hydrocolloids. Handbook of hydrocolloids 2000, 1-19. CRC Press, Taylor & Francis, Boca Raton. G.O. Phillips, P.A. Williams (Eds.)
3. Labeau M-P. Guar and guar derivatives. In: Matyjaszewski K, Möller M, editors. Polymer science: a comprehensive reference, vol. 10. Polymers for a sustainable environment and green energy. McGrath JE, Hickner MA, Höfer R, (Volume editors.) Amsterdam, Oxford, Waltham: Elsevier; 2012. p. 195-203
4. Hublik G. Xanthan. In: Matyjaszewski K, Möller M, editors. Polymer science: a comprehensive reference, vol. 10, Polymers for a sustainable environment and green energy. McGrath JE, Hickner MA, Höfer R, (Volume editors.) Amsterdam, Oxford, Waltham: Elsevier; 2012. p. 221-9
5. Muzzarelli RAA. Nanochitins and nanochitosans, paving the way to eco-friendly and energy-saving exploitation of marine resources. In: Matyjaszewski K, Möller M, editors. Polymer science: a comprehensive reference, vol. 10, Polymers for a sustainable environment and green energy. McGrath JE, Hickner MA, Höfer R, (Volume editors.) Amsterdam, Oxford, Waltham: Elsevier; 2012. p. 153-64
6. Keenan TR. Gelatin. In: Matyjaszewski K, Möller M, editors. Polymer science: a comprehensive reference, vol. 10, Polymers for a sustainable environment and green energy. McGrath JE, Hickner MA, Höfer R, (Volume editors.) Amsterdam, Oxford, Waltham: Elsevier; 2012. p. 237-47
7. Skjåk-Bræk G, Draget KI. Alginates: Properties and Applications. In: Matyjaszewski K, Möller M, editors. Polymer science: a comprehensive reference, vol. 10, Polymers for a sustainable environment and green energy. McGrath JE, Hickner MA, Höfer R, (Volume editors.) Amsterdam, Oxford, Waltham: Elsevier; 2012. p. 213-20
8. Stephen A.M., Churms S.C. Introduction. Food polysaccharides and their application 2006, 1-24. CRC Press, Taylor & Francis, Boca Raton. A.M. Stephen, G.O. Phillips, P.A. Williams (Eds.)
9. Zobel H.F., Stephen A.M. Starch: structure, analysis, and application. Food polysaccharides and their application 2006, 25-83. CRC Press, Taylor & Francis, Boca Raton. A.M. Stephen, G.O. Phillips, P.A. Williams (Eds.)
10. Wurzburg O.B. Modified starches. Food polysaccharides and their application 2006, 88-118. CRC Press, Taylor & Francis, Boca Raton. A.M. Stephen, G.O. Phillips, P.A. Williams (Eds.)
11. Abbas K.A., Khalil S.K., Hussin A.S.M. Modified starches and their usages in selected food products: a review study. J Agric Sci 2010, 2:90-100
12. Wang Q., Cui S.W. Understanding the physical properties of food polysaccharides. Food carbohydrates: chemistry, physical properties and applications 2005, CRC Press, Taylor & Francis, Boca Raton. S.W. Cui (Ed.)
13. Cerqueira M.A., Bourbon A.I., Pinheiro A.C., Martins J.T., Souza B.W.S., Teixeira J.A., et al. Galactomannans use in the development of edible films/coatings for food applications. Trends Food Sci Technol 2011, 22(12):662-671
14. Varela P., Pintor A., Fiszman S. How hydrocolloids affect the temporal oral perception of ice cream. Food Hydrocoll 2014, 36:220-228
15. Cerqueira M.A., Pinheiro A.C., Souza B.W.S., Lima á.M.P., Ribeiro C., Miranda C., et al. Extraction, purification and characterization of galactomannans from non-traditional sources. Carbohydr Polym 2009, 75(3):408-414
16. Bourbon A.I., Pinheiro A.C., Ribeiro C., Miranda C., Maia J.M., Teixeira J.A., et al. Characterization of galactomannans extracted from seeds of Gleditsia triacanthos and Sophora japonica through shear and extensional rheology: comparison with guar gum and locust bean gum. Food Hydrocoll 2010, 24(2-3):184-192
17. Souza B.W.S., Cerqueira M.A., Bourbon A.I., Pinheiro A.C., Martins J.T., Teixeira J.A., et al. Chemical characterization and antioxidant activity of sulfated polysaccharide from the red seaweed Gracilaria birdiae. Food Hydrocoll 2012, 27(2):287-292
18. Jian H.l., Cristhian C., Zhang W.M., Jiang J.X. Influence of dehulling pretreatment on physicochemical properties of Gleditsia sinensis Lam. gum. Food Hydrocoll 2011, 25(5):1337-1343
19. You Q., Yin X., Zhang S., Jiang Z. Extraction, purification, and antioxidant activities of polysaccharides from Tricholoma mongolicum Imai. Carbohydr Polym 2014, 99:1-10
20. Jindal M., Kumar V., Rana V., Tiwary A.K. Exploring potential new gum source Aegle marmelos for food and pharmaceuticals: physical, chemical and functional performance. Ind Crops Prod 2013, 45:312-318
21. Patel S., Goyal A. Functional oligosaccharides: production, properties and applications. World J Microbiol Biotechnol 2011, 27(5):1119-1128
22. Buriti F.C.A., dos Santos K.M.O., Sombra V.c.G., Maciel J.S., Teixeira Sá D.M.A., Salles H.O., et al. Characterisation of partially hydrolysed galactomannan from Caesalpinia pulcherrima seeds as a potential dietary fibre. Food Hydrocoll 2014, 35:512-521
23. Barreteau H., Delattre C., Michaud P. Production of oligosaccharides as promising new food additive generation. Food Technol Biotechnol 2006, 44(3):323-333
24. Roberfroid M. Prebiotics: the concept revisited. J Nutr 2007, 137(3):830S-837S
25. Manning T.S., Gibson G.R. Prebiotics. Best Pract Res Clin Gastroenterol 2004, 18(2):287-298
26. Gibson G.R., Probert H.M., Van Loo J., Rastall R.A., Roberfroid M.B. Dietary modulation of the human colonic microbiota: updating the concept of prebiotics. Nutr Res Rev 2004, 17(2):259-275
27. Aachary A.A., Prapulla S.G. Xylooligosaccharides (XOS) as an emerging prebiotic: microbial synthesis, utilization, structural characterization, bioactive properties, and applications. Compr Rev Food Sci Food Saf 2011, 10(1):2-16
28. Torres D.P.M., Gonçalves M.d.P., Teixeira J.A., Rodrigues L.R. Galacto-oligosaccharides: production, properties, applications, and significance as prebiotics. Compr Rev Food Sci Food Saf 2010, 9(5):438-454
29. Charalampopoulos D., Rastall R.A. Prebiotics in foods. Curr Opin Biotechnol 2012, 23(2):187-191
30. Al-Sheraji S.H., Ismail A., Manap M.Y., Mustafa S., Yusof R.M., Hassan F.A. Prebiotics as functional foods: a review. J Funct Foods 2013, 5(4):1542-1553
31. Havenaar R., Bonnin-Marol S., Van Dokkum W., Petitet S., Schaafsma G. Inulin: fermentation and microbial ecology in the intestinal tract. Food Rev Int 1999, 15(1):109-120
32. Peters D. Raw materials. Adv Biochem Eng/Biotechnol 2007, 105:1-30
33. Moshfegh A.J., Friday J.E., Goldman J.P., Ahuja J.K.C. Presence of inulin and oligofructose in the diets of Americans. J Nutr 1999, 129(7):1407S-1411S
34. Emanuel M.A., Benkeblia N., Lopez M.G. Variation of saccharides and fructo-oligosaccharides (FOS) in carambola (Averrhoa carambola) and june plum (Spondias dulcis) during ripening stages. Acta Hortic (ISHS) 2013, 1012:77-82
35. Roberfroid M.B. Inulin-type fructans: functional food ingredients. J Nutr 2007, 137(11):2493S-2502S
36. Gänzle M.G. Enzymatic synthesis of galacto-oligosaccharides and other lactose derivatives (hetero-oligosaccharides) from lactose. Int Dairy J 2012, 22(2):116-122
37. Coelho E., Rocha M.A., Saraiva J.A., Coimbra M.A. Microwave superheated water and dilute alkali extraction of brewers' spent grain arabinoxylans and arabinoxylo-oligosaccharides. Carbohydr Polym 2014, 99:415-422
38. Chen R., Li Y., Dong H., Liu Z., Li S., Yang S., et al. Optimization of ultrasonic extraction process of polysaccharides from Ornithogalum Caudatum Ait and evaluation of its biological activities. Ultrason Sonochem 2012, 19(6):1160-1168
39. Shi M., Yang Y., Hu X., Zhang Z. Effect of ultrasonic extraction conditions on antioxidative and immunomodulatory activities of a Ganoderma lucidum polysaccharide originated from fermented soybean curd residue. Food Chem 2014, 155:50-56
40. Sanz T., Salvador A., Fiszman S.M. Evaluation of four types of resistant starch in muffin baking performance and relationship with batter rheology. Eur Food Res Technol 2008, 227(3):813-819
41. Fuentes-Zaragoza E., Riquelme-Navarrete M.J., Sánchez-Zapata E., Pérez-álvarez J.A. Resistant starch as functional ingredient: a review. Food Res Int 2010, 43(4):931-942
42. Peressini D., Sensidoni A. Effect of soluble dietary fibre addition on rheological and breadmaking properties of wheat doughs. J Cereal Sci 2009, 49(2):190-201
43. Xiong G., Cheng W., Ye L., Du X., Zhou M., Lin R., et al. Effects of konjac glucomannan on physicochemical properties of myofibrillar protein and surimi gels from grass carp (Ctenopharyngodon idella). Food Chem 2009, 116(2):413-418
44. Tárrega A., Martínez M., Vélez-Ruiz J.F., Fiszman S. Hydrocolloids as a tool for modulating the expected satiety of milk-based snacks. Food Hydrocoll 2014, 39:51-57
45. Vergara-Valencia N., Granados-Pérez E., Agama-Acevedo E., Tovar J., Ruales J., Bello-Pérez L.A. Fibre concentrate from mango fruit: characterization, associated antioxidant capacity and application as a bakery product ingredient. LWT Food Sci Technol 2007, 40(4):722-729
46. Silva E., Birkenhake M., Scholten E., Sagis L.M.C., van der Linden E. Controlling rheology and structure of sweet potato starch noodles with high broccoli powder content by hydrocolloids. Food Hydrocoll 2013, 30(1):42-52
47. Parimala K.R., Sudha M.L. Effect of hydrocolloids on the rheological, microscopic, mass transfer characteristics during frying and quality characteristics of puri. Food Hydrocoll 2012, 27(1):191-200
48. García M.A., Ferrero C., Bértola N., Martino M., Zaritzky N. Edible coatings from cellulose derivatives to reduce oil uptake in fried products. Innovative Food Sci Emerg Technol 2002, 3(4):391-397
49. Union E. Directive 2009/32/EC of the European Parliament and of the Council 23 April 2009 on the approximation of the laws of the Member States on extraction solvents used in the production of foodstuffs and food ingredients 2009, L141-3-L141/11
50. Palcic M.M. Biocatalytic synthesis of oligosaccharides. Curr Opin Biotechnol 1999, 10(6):616-624
51. Prapulla S.G., Subhaprada V., Karanth N.G. Microbial production of oligosaccharides: a review. Adv Appl Microbiol 2000, 47:299-343
52. Kango N., Jain S.C. Production and properties of microbial inulinases: recent advances. Food Biotechnol 2011, 25(3):165-212
53. Pandey A., Soccol C.R., Selvakumar P., Soccol V.T., Krieger N., Fontana J.D. Recent developments in microbial inulinases-its production, properties, and industrial applications. Appl Biochem Biotechnol 1999, 81(1):35-52
54. Singh R.S., Singh R.P. Production of fructooligosaccharides from inulin by endoinulinases and their prebiotic potential. Food Technol Biotechnol 2010, 48(4):435-450
55. Singh P., Gill P.K. Production of inulinases: recent advances. Food Technol Biotechnol 2006, 44(2):151-162
56. Sangeetha P.T., Ramesh M.N., Prapulla S.G. Recent trends in the microbial production, analysis and application of Fructooligosaccharides. Trends Food Sci Technol 2005, 16(10):442-457
57. Yun J.W. Fructooligosaccharides-occurrence, preparation, and application. Enzyme Microb Technol 1996, 19(2):107-117
58. Dominguez A.L., Rodrigues L.R., Lima N.M., Teixeira J.A. An Overview of the recent developments on fructooligosaccharide production and applications. Food Bioprocess Technol 2014, 7(2):324-337
59. Maiorano A.E., Piccoli R.M., Da Silva E.S., De Andrade Rodrigues M.F. Microbial production of fructosyltransferases for synthesis of prebiotics. Biotechnol Lett 2008, 30(11):1867-1877
60. Guio F., Rodriguez M.A., Almeciga-Diaz C.J., Sanchez O.F. Recent trends in fructooligosaccharides production. Recent Pat Food Nutr Agric 2009, 1(3):221-230
61. Gosling A., Stevens G.W., Barber A.R., Kentish S.E., Gras S.L. Recent advances refining galactooligosaccharide production from lactose. Food Chem 2010, 121(2):307-318
62. Lamsal B.P. Production, health aspects and potential food uses of dairy prebiotic galactooligosaccharides. J Sci Food Agric 2012, 92(10):2020-2028
63. Mussatto S.I., Aguilar C.N., Rodrigues L.R., Teixeira J.A. Fructooligosaccharides and beta-fructofuranosidase production by Aspergillus japonicus immobilized on lignocellulosic materials. J Mol Catal B-Enzymatic 2009, 59(1-3):76-81
64. Sangeetha P.T., Ramesh M.N., Prapulla S.G. Production of fructo-oligosaccharides by fructosyl transferase from Aspergillus oryzae CFR 202 and Aureobasidium pullulans CFR 77. Process Biochem 2004, 39(6):753-758
65. Onishi N., Tanaka T. Purification and properties of a novel thermostable galacto-oligosaccharide producing beta-galactosidase from Sterigmatomyces elviae CBS8119. Appl Environ Microbiol 1996, 62(2):747. (vol. 61, pg 4028, 1995)
66. Nobre C., Teixeira J.A., Rodrigues L.R. Fructo-oligosaccharides purification from a fermentative broth using an activated charcoal column. New Biotechnol 2012, 29(3):395-401
67. Yu L., O'Sullivan D.J. Production of galactooligosaccharides using a hyperthermophilic beta-galactosidase in permeabilized whole cells of Lactococcus lactis. J Dairy Sci 2014, 97(2):694-703
68. Neri D.F.M., Balc+úo V.M., Costa R.S., Rocha I.C.A.P., Ferreira E.n.M.F.C., Torres D.P.M., et al. Galacto-oligosaccharides production during lactose hydrolysis by free Aspergillus oryzae beta-galactosidase and immobilized on magnetic polysiloxane-polyvinyl alcohol. Food Chem 2009, 115(1):92-99
69. Huerta L.M., Vera C., Guerrero C., Wilson L., Illanes A.s Synthesis of galacto-oligosaccharides at very high lactose concentrations with immobilized beta-galactosidases from Aspergillus oryzae. Process Biochem 2011, 46(1):245-252
70. Hung M.N., Lee B. Purification and characterization of a recombinant beta-galactosidase with transgalactosylation activity from Bifidobacterium infantis HL96. Appl Microbiol Biotechnol 2002, 58(4):439-445
71. Cho Y.J., Shin H.J., Bucke C. Purification and biochemical properties of a galactooligosaccharide producing beta-galactosidase from Bullera singularis. Biotechnol Lett 2003, 25(24):2107-2111
72. Stevenson D.E., Stanley R.A., Furneaux R.H. Oligosaccharide and alkyl beta-galactopyranoside synthesis from lactose with Caldocellum saccharolyticum beta-glycosidase. Enzyme Microb Technol 1996, 18(8):544-549
73. Rodriguez-Colinas B., de Abreu M.A., Fernandez-Arrojo L., de Beer R., Poveda A., Jimenez-Barbero J., et al. Production of galacto-oligosaccharides by the beta-galactosidase from Kluyveromyces lactis: comparative analysis of permeabilized cells versus soluble enzyme. J Agric Food Chem 2011, 59(19):10477-10484
74. Braga A.R.C., Manera A.P., Ores J.C., Sala L., Maugeri F., Kalil S.J. Kinetics and thermal properties of crude and purified beta-galactosidase with potential for the production of galactooligosaccharides. Food Technol Biotechnol 2013, 51(1):45-52
75. Park H.Y., Kim H.J., Lee J.K., Kim D., Oh D.K. Galactooligosaccharide production by a thermostable beta-galactosidase from Sulfolobus solfataricus. World J Microbiol Biotechnol 2008, 24(8):1553-1558
76. Onishi N., Tanaka T. Purification and Properties of A Novel thermostable galacto-oligosaccharide-producing beta-galactosidase from Sterigmatomyces elviae Cbs8119. Appl Environ Microbiol 1995, 61(11):4026-4030
77. Dominguez A., Nobre C., Rodrigues L.R., Peres A.M., Torres D., Rocha I., et al. New improved method for fructooligosaccharides production by Aureobasidium pullulans. Carbohydr Polym 2012, 89(4):1174-1179
78. Yoshikawa J., Amachi S., Shinoyama H., Fujii T. Production of fructooligosaccharides by crude enzyme preparations of beta-fructofuranosidase from Aureobasidium pullulans. Biotechnol Lett 2008, 30(3):535-539
79. Jung K.H., Bang S.H., Oh T.K., Park H.J. Industrial production of fructooligosaccharides by immobilized cells of Aureobasidium pullulans in a packed bed reactor. Biotechnol Lett 2011, 33(8):1621-1624
80. Ganaie M.A., Gupta U.S., Kango N. Screening of biocatalysts for transformation of sucrose to fructooligosaccharides. J Mol Catal B Enzym 2013, 97:12-17
81. Mussatto S.I., Ballesteros L.F., Martins S., Maltos D.A.F., Aguilar C.N., Teixeira J.A. Maximization of fructooligosaccharides and beta-fructofuranosidase production by Aspergillus japonicus under solid-state fermentation conditions. Food Bioprocess Technol 2013, 6(8):2128-2134
82. Sheu D.C., Chang J.Y., Wang C.Y., Wu C.T., Huang C.J. Continuous production of high-purity fructooligosaccharides and ethanol by immobilized Aspergillus japonicus and Pichia heimii. Bioprocess Biosyst Eng 2013, 36(11):1745-1751
83. Chiang C.J., Lee W.C., Sheu D.C., Duan K.J. Immobilization of beta-fructofuranosidases from Aspergillus on methacrylamide-based polymeric beads for production of fructooligosaccharides. Biotechnol Prog 1997, 13(5):577-582
84. Zhou K., Liu D.M., Fan M.K., Ye J.L. Production of fructooligosaccharides using free-whole-cell biotransformation by Aspergillus niger CGMCC No. 6640. Mod Food Sci Technol 2013, 29(8):1967-1972
85. Sangeetha P.T., Ramesh M.N., Prapulla S.G. Production of fructosyl transferase by Aspergillus oryzae CFR 202 in solid-state fermentation using agricultural by-products. Appl Microbiol Biotechnol 2004, 65(5):530-537
86. Prata M.B., Mussatto S.I., Rodrigues L.R., Teixeira J.A. Fructooligosaccharide production by Penicillium expansum. Biotechnol Lett 2010, 32(6):837-840
87. Mussatto S.I., Prata M.B., Rodrigues L.R., Teixeira J.A. Production of fructooligosaccharides and beta-fructofuranosidase by batch and repeated batch fermentation with immobilized cells of Penicillium expansum. Eur Food Res Technol 2012, 235(1):13-22
88. Yun J.W., Song S.K. The production of high-content fructo-oligosaccharides from sucrose by the mixed-enzyme system of fructosyltransferase and glucose-oxidase. Biotechnol Lett 1993, 15(6):573-576
89. Nobre C., Teixeira J.A., Rodrigues L.R. New trends and technological challenges in the industrial production and purification of fructo-oligosaccharides. Crit Rev Food Sci Nutr 2013, 10.1080/10408398.2012.697082
90. Sheu D.C., Duan K.J., Cheng C.Y., Bi J.L., Chen J.Y. Continuous production of high-content fructooligosaccharides by a complex cell system. Biotechnol Prog 2002, 18(6):1282-1286
91. Yun J.W., Lee M.G., Song S.K. Batch production of high-content fructo-oligosaccharides from sucrose by the mixed-enzyme system of [beta]-fructofuranosidase and glucose oxidase. J Ferment Bioeng 1994, 77(2):159-163
92. Lin T.J., Lee Y.C. High-content fructooligosaccharides production using two immobilized microorganisms in an internal-loop airlift bioreactor. J Chin Inst Chem Eng 2008, 39(3):211-217
93. Nishizawa K., Nakajima M., Nabetani H. Kinetic study on transfructosylation by β-fructofuranosidase from Aspergillus niger ATCC 20611 and availability of a membrane reactor for Fructooligosaccharide production. Food Sci Technol Res 2001, 7(1):39-44
94. Boon M.A., van't Riet K., Janssen A.E.M. Enzymatic synthesis of oligosaccharides: product removal during a kinetically controlled reaction. Biotechnol Bioeng 2000, 70(4):411-420
95. Ajisaka K., Nishida H., Fujimoto H. Use of an activated carbon column for the synthesis of disaccharides by use of a reversed hydrolysis activity of beta-galactosidase. Biotechnol Lett 1987, 9(6):387-392
96. Crittenden R.G., Playne M.J. Purification of food-grade oligosaccharides using immobilised cells of Zymomonas mobilis. Appl Microbiol Biotechnol 2002, 58(3):297-302
97. Yoon S.H., Mukerjea R., Robyt J.F. Specificity of yeast (Saccharomyces cerevisiae) in removing carbohydrates by fermentation. Carbohydr Res 2003, 338(10):1127-1132
98. Goulas A., Tzortzis G., Gibson G.R. Development of a process for the production and purification of alpha-and beta-galactooligosaccharides from Bifidobacterium bifidum NCIMB 41171. Int Dairy J 2007, 17(6):648-656
99. Hernandez O., Ruiz-Matute A.I., Olano A., Moreno F.J., Sanz M.L. Comparison of fractionation techniques to obtain prebiotic galactooligosaccharides. Int Dairy J 2009, 19(9):531-536
100. Sanz M.L., Polemis N., Morales V., Corzo N., Drakoularakou A., Gibson G.R., et al. In vitro investigation into the potential prebiotic activity of honey oligosaccharides. J Agric Food Chem 2005, 53(8):2914-2921
101. Leiva M.H.L., Guzman M. Formation of oligosaccharides during enzymic hydrolysis of milk whey permeates. Process Biochem 1995, 30(8):757-762
102. Sarney D.B., Hale C., Frankel G., Vulfson E.N. A novel approach to the recovery of biologically active oligosaccharides from milk using a combination of enzymatic treatment and nanofiltration. Biotechnol Bioeng 2000, 69(4):461-467
103. Goulas A.K., Kapasakalidis P.G., Sinclair H.R., Rastall R.A., Grandison A.S. Purification of oligosaccharides by nanofiltration. J Membr Sci 2002, 209(1):321-335
104. Li W.Y., Li J.D., Chen T.Q., Chen C.X. Study on nanotiltration for purifying fructo-oligosaccharides I. Operation modes. J Membr Sci 2004, 245(1-2):123-129
105. Kamada T., Nakajima M., Nabetani H., Saglam N., Iwamoto S. Availability of membrane technology for purifying and concentrating oligosaccharides. Eur Food Res Technol 2002, 214(5):435-440
106. Gulec H.A., Topacli A., Topacli C., Albayrak N., Mutlu M. Modification of cellulose acetate membrane via low-pressure plasma polymerization for sugar separation applications: Part I. Membrane development and characterization. J Membr Sci 2010, 350(1-2):310-321
107. Botelho-Cunha V.A., Mateus M., Petrus J.C.C., de Pinho M.N. Tailoring the enzymatic synthesis and nanofiltration fractionation of galacto-oligosaccharides. Biochem Eng J 2010, 50(1-2):29-36
108. Kuhn R.C., Palacio L., Prádanos P., Hernández A., Filho F.M. Selection of membranes for purification of fructooligosaccharides. Desalination Water Treat 2011, 27(1-3):18-24
109. Priem B., Gilbert M., Wakarchuk W.W., Heyraud A., Samain E. A new fermentation process allows large-scale production of human milk oligosaccharides by metabolically engineered bacteria. Glycobiology 2002, 12(4):235-240
110. Kawazoe N., Okada H., Fukushi E., Yarnarnori A., Onodera S., Kawabata J., et al. Two novel oligosaccharides isolated from a beverage produced by fermentation of a plant extract. Carbohydr Res 2008, 343(3):549-554
111. Kaplan H., Hutkins R.W. Metabolism of fructooligosaccharides by Lactobacillus paracasei 1195. Appl Environ Microbiol 2003, 69(4):2217-2222
112. Kuhn R.C., Maugeri F. Purification of fructoligosaccharides in active carbon fixed-bed column. New Biotechnol 2010, 25:S182
113. Sai Prakash B., Suyama K., Itoh T., Adachi S. Structure elucidation of major galacto oligosaccharides formed by growing culture of Trichoderma harzianum. J Agric Food Chem 1989, 37(2):334-337
114. Weston R.J., Brocklebank L.K. The oligosaccharide composition of some New Zealand honeys. Food Chem 1999, 64(1):33-37
115. Whistler R.L., Durso D.F. Chromatographic separation of sugars on charcoal. J Am Chem Soc 1950, 72(2):677-679
116. Swallow K.W., Low N.H. Analysis and quantitation of the carbohydrates in honey using high-performance liquid-chromatography. J Agric Food Chem 1990, 38(9):1828-1832
117. Hidaka H., Hirayama M., Sumi N. A fructooligosaccharide-producing enzyme from Aspergillus Niger Atcc-20611. Agric Biol Chem 1988, 52(5):1181-1187
118. Morales V., Sanz M.L., Olano A., Corzo N. Rapid separation on activated charcoal of high oligosaccharides in honey. Chromatographia 2006, 64(3-4):233-238
119. Uchiyama T., Yoneda I., Murakami Y. Identification of fructo-oligosaccharides from the bulbs of Lycoris radiata Herbert. Agric Biol Chem 1985, 49(11):3315-3317
120. Morales V., Corzo N., Sanz M.L. HPAEC-PAD oligosaccharide analysis to detect adulterations of honey with sugar syrups. Food Chem 2008, 107(2):922-928
121. Vankova K., Gramblicka M., Polakovic M. Single-component and binary adsorption equilibria of fructooligosaccharides, glucose, fructose, and sucrose on a Ca-form cation exchanger. J Chem Eng Data 2010, 55(1):405-410
122. Vankova K., Acai P., Polakovic M. Modelling of fixed-bed adsorption of mono-, di-, and fructooligosaccharides on a cation-exchange resin. Biochem Eng J 2010, 49(1):84-88
123. Vankova K., Polakovic M. Design of fructooligosaccharide separation using simulated moving-bed chromatography. Chem Eng Technol 2012, 35(1):161-168
124. Nobre C., Suvarov P., De Weireld G. Evaluation of commercial resins for fructo-oligosaccharide separation. New Biotechnol 2014, 31(1):55-63
125. Gramblicka M., Polakovic M. Adsorption equilibria of glucose, fructose, sucrose, and fructooligosaccharides on cation exchange resins. J Chem Eng Data 2007, 52(2):345-350
126. Adachi S., Watanabe T., Kohashi M. Role of swelling pressure on the distribution coefficient of maltooligosaccharide in a cation-exchange resin. Agric Biol Chem 1989, 53(12):3203-3208
127. Adachi S., Mizuno T., Matsuno R. Concentration-dependence of the distribution coefficient of maltooligosaccharides on a cation-exchange resin. J Chromatogr A 1995, 708(2):177-183
128. Lei H.J., Bao Z.B., Xing H.B., Yang Y.W., Ren Q.L., Zhao M.M., et al. Adsorption behavior of glucose, xylose, and arabinose on five different cation exchange resins. J Chem Eng Data 2010, 55(2):735-738
129. Kawase M., Pilgrim A., Araki T., Hashimoto K. Lactosucrose production using a simulated moving bed reactor. Chem Eng Sci 2001, 56(2):453-458
130. Geisser A., Hendrich T., Boehm G., Stahl B. Separation of lactose from human milk oligosaccharides with simulated moving bed chromatography. J Chromatogr A 2005, 1092(1):17-23
131. Mostafazadeh A.K., Sarshar M., Javadian S., Zarefard M.R., Haghighi Z.A. Separation of fructose and glucose from date syrup using resin chromatographic method: experimental data and mathematical modeling. Sep Purif Technol 2011, 79(1):72-78
132. Saari P., Heikkila H., Hurme M. Adsorption equilibria of arabinose, fructose, galactose, glucose, mannose, rhamnose, sucrose, and xylose on ion-exchange resins. J Chem Eng Data 2010, 55(9):3462-3467
133. Nobre C., Santos M.J., Dominguez A., Torres D., Rocha O., Peres A.M., et al. Comparison of adsorption equilibrium of fructose, glucose and sucrose on potassium gel-type and macroporous sodium ion-exchange resins. Anal Chim Acta 2009, 654(1):71-76
134. Pedruzzi I., Silva E.A.B., Rodrigues A.E. Selection of resins, equilibrium and sorption kinetics of lactobionic acid, fructose, lactose and sorbitol. Sep Purif Technol 2008, 63(3):600-611
135. Nowak J., Gedicke K., Antos D., Piatkowski W., Seidel-Morgenstern A. Synergistic effects in competitive adsorption of carbohydrates on an ion-exchange resin. J Chromatogr A 2007, 1164(1-2):224-234
136. Vente J.A., Bosch H., de Haan A.B., Bussmann P.J.T. Comparison of sorption isotherms of mono-and disaccharides relevant to oligosaccharide separations for Na, K, and Ca loaded cation exchange resins. Chem Eng Commun 2005, 192(1):23-33
137. Izydorczyk M., Cui S.W., Wang Q. Polysaccharide gums: structures, functional properties, and applications. Food carbohydrates: chemistry, physical properties and applications 2005, CRC Press, Taylor & Francis, Boca Raton. S.W. Cui (Ed.)
138. Crittenden R.G., Playne M.J. Production, properties and applications of food-grade oligosaccharides. Trends Food Sci Technol 1996, 7(11):353-361
139. Franck A. Technological functionality of inulin and oligofructose. Br J Nutr 2002, 87:S287-S291
140. Padma S.I., Prabhasankar P. Prebiotics: application in bakery and pasta products. Crit Rev Food Sci Nutr 2014, 54(4):511-522
141. Panesar P.S., Kumari S., Panesar R. Biotechnological approaches for the production of prebiotics and their potential applications. Crit Rev Biotechnol 2013, 33(4):345-364
142. Macfarlane G.T., Steed H., Macfarlane S. Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics. J Appl Microbiol 2008, 104(2):305-344
143. Crittenden R.G., Playne M.J. Prebiotics. Handbook of probiotics and prebiotics 2009, 535-596. A John Wiley & Sons, Inc., New Jersey. Y.K. Lee, S. Salminem (Eds.)
144. Brummer Y., Cui S.W. Understanding carbohydrate analysis. Food carbohydrates: chemistry, physical properties and applications 2005, 67-104. CRC Press, Taylor & Francis, Boca Raton. S.W. Cui (Ed.)
145. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) Scientific opinion on dietary reference values for carbohydrates and dietary fibre. EFSA J 2010, 8(3):1462-1539. (acceded in 26.03.2014) http://www.efsa.europa.eu/en/search/doc/1462.pdf
146. Gidley M.J. Hydrocolloids in the digestive tract and related health implications. Curr Opin Colloid & Interface Sci 2013, 18(4):371-378
147. Lindström C., Holst O., Hellstrand P., öste R., Andersson K.E. Evaluation of commercial microbial hydrocolloids concerning their effects on plasma lipids and caecal formation of SCFA in mice. Food Hydrocoll 2012, 28(2):367-372
148. Ellis P.R., Roberts F.G., Low A.G., Morgan L.M. The effect of high-molecular-weight guar gum on net apparent glucose absorption and net apparent insulin and gastric inhibitory polypeptide production in the growing pig: relationship to rheological changes in jejunal digesta. Br J Nutr 1995, 74(4):539-556
149. Yamatoya K., Kuwano K., Suzuki J. Effects of hydrolyzed guar gum on cholesterol and glucose in humans. Food Hydrocoll 1997, 11:239-242
150. Gibson G.R. Dietary modulation of the human gut microflora using the prebiotics oligofructose and inulin. J Nutr 1999, 129(7):1438S-1441S
151. Gibson G.R., Roberfroid M.B. Dietary modulation of the human colonic microbiota-introducing the concept of prebiotics. J Nutr 1995, 125(6):1401-1412
152. Yamashita K., Kawai K., Itakura M. Effects of fructo-oligosaccharides on blood-glucose and serum-lipids in diabetic subjects. Nutr Res 1984, 4(6):961-966
153. Causey J.L., Feirtag J.M., Gallaher D.D., Tungland B.C., Slavin J.L. Effects of dietary inulin on serum lipids, blood glucose and the gastrointestinal, environment in hypercholesterolemic men. Nutr Res 2000, 20(2):191-201
154. Davidson M.H., Maki K.C., Synecki C., Torri S.A., Drennan K.B. Effects of dietary inulin on serum lipids in men and women with hypercholesterolemia. Nutr Res 1998, 18(3):503-517
155. Williams C.M., Jackson K.G. Inulin and oligofructose: effects on lipid metabolism from human studies. Br J Nutr 2002, 87:S261-S264
156. Russo F., Chimienti G., Riezzo G., Pepe G., Petrosillo G., Chiloiro M., et al. Inulin-enriched pasta affects lipid profile and Lp(a) concentrations in Italian young healthy male volunteers. Eur J Nutr 2008, 47(8):453-459
157. Bonsu N.K., Johnson C.S., McLeod K.M. Can dietary fructans lower serum glucose?. J Diabetes 2011, 3(1):58-66
158. Pereira D.I.A., Gibson G.R. Effects of consumption of probiotics and prebiotics on serum lipid levels in humans. Crit Rev Biochem Mol Biol 2002, 37(4):259-281
159. Ooi L.G., Liong M.T. Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings. Int J Mol Sci 2010, 11(6):2499-2522
160. Coxam V. Inulin-type fructans and bone health: state of the art and perspectives in the management of osteoporosis. Br J Nutr 2005, 93:S111-S123
161. Franck A. Prebiotics stimulate calcium absorption: a review. Food Aust 2005, 57(12):530-532
162. Scholz-Ahrens K.E., Schrezenmeir J. Inulin, oligofructose and mineral metabolism-experimental data and mechanism. Br J Nutr 2002, 87:S179-S186
163. Abrams S.A., Griffin I.J., Hawthorne K.M., Liang L., Gunn S.K., Darlington G., et al. A combination of prebiotic short-and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr 2005, 82(2):471-476
164. Pool-Zobel B., Van Loo J., Rowland I., Roberfroid M.B. Experimental evidences on the potential of prebiotic fructans to reduce the risk of colon cancer. Br J Nutr 2002, 87(Suppl. 2):S273-S281
165. Pool-Zobel B.L. Inulin-type fructans and reduction in colon cancer risk: review of experimental and human data. Br J Nutr 2005, 93:S73-S90
166. Munjal U., Glei M., Pool-Zobel B.L., Scharlau D. Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis. Br J Nutr 2009, 102(5):663-671
167. Fotiadis C.I., Stoidis C.N., Spyropoulos B.G., Zografos E.D. Role of probiotics, prebiotics and synbiotics in chemoprevention for colorectal cancer. World J Gastroenterol 2008, 14(42):6453-6457
168. Taper H.S., Roberfroid M.B. Inulin/oligofructose and anticancer therapy. Br J Nutr 2002, 87:S283-S286
169. Gibson G.R. Dietary modulation of the human gut microflora using prebiotics. Br J Nutr 1998, 80(4):S209-S212
170. Guarner F. Studies with inulin-type fructans on intestinal infections, permeability, and inflammation. J Nutr 2007, 137(11):2568S-2571S
171. Gibson G.R., McCartney A.L., Rastall R.A. Prebiotics and resistance to gastrointestinal infections. Br J Nutr 2005, 93:S31-S34
172. Sabater-Molina M., Larque E., Torrella F., Zamora S. Dietary fructooligosaccharides and potential benefits on health. J Physiol Biochem 2009, 65(3):315-328
173. Kleessen B., Sykura B., Zunft H.J., Blaut M. Effects of inulin and lactose on fecal microflora, microbial activity, and bowel habit in elderly constipated persons. Am J Clin Nutr 1997, 65(5):1397-1402
174. Cummings J.H., Christie S., Cole T.J. A study of fructo oligosaccharides in the prevention of travellers' diarrhoea. Aliment Pharmacol Ther 2001, 15(8):1139-1145
175. Duggan C., Penny M.E., Hibberd P., Gil A., Huapaya A., Cooper A., et al. Oligofructose-supplemented infant cereal: 2 randomized, blinded, community-based trials in Peruvian infants. Am J Clin Nutr 2003, 77(4):937-942
176. Casellas F., Borruel N., Torrejon A., Varela E., Antolin M., Guarner F., et al. Oral oligofructose-enriched inulin supplementation in acute ulcerative colitis is well tolerated and associated with lowered faecal calprotectin. Aliment Pharmacol Ther 2007, 25(9):1061-1067
177. Lindsay J.O., Whelan K., Stagg A.J., Gobin P., Al-Hassi H.O., Rayment N., et al. Clinical, microbiological, and immunological effects of fructo-oligosaccharide in patients with Crohn's disease. Gut 2006, 55(3):348-355
178. Welters C.F.M., Heineman E., Thunnissen F.B.J.M., van den Bogaard A.E.J.M., Soeters P.B., Baeten C.G.M.I. Effect of dietary inulin supplementation on inflammation of pouch mucosa in patients with an heal pouch-anal anastomosis. Dis Colon Rectum 2002, 45(5):621-627
179. Bouhnik Y., Raskine L., Simoneau G., Paineau D., Bornet F. The capacity of short-chain fructo-oligosaccharides to stimulate faecal bifidobacteria: a dose-response relationship study in healthy humans. Nutr J 2006, 5:8
180. Jenkins D.J.A., Kendall C.W.C., Vuksan V. Inulin, oligofructose and intestinal function. J Nutr 1999, 129(7):1431S-1433S
181. Gibson G.R., Beatty E.R., Wang X., Cummings J.H. Selective stimulation of bifidobacteria in the human colon by oligofructose and inulin. Gastroenterol 1995, 108(4):975-982
182. Kubota T., Shimojo N., Nonaka K., Yamashita M., Ohara O., Igoshi Y., et al. Prebiotic consumption in pregnant and lactating women increases IL-27 expression in human milk. Br J Nutr 2013, 111(4):625-632
183. DiBaise J.K., Zhang H., Crowell M.D., Krajmalnik-Brown R., Decker G.A., Rittmann B.E. Gut microbiota and its possible relationship with obesity. Mayo Clin Proc 2008, 83(4):460-469
184. Cani P.D., Joly E., Horsmans Y., Delzenne N.M. Oligofructose promotes satiety in healthy human: a pilot study. Eur J Clin Nutr 2006, 60(5):567-572
185. Abrams S.A., Griffin I.J., Hawthorne K.M., Ellis K.J. Effect of prebiotic supplementation and calcium intake on body mass Index. J Pediatr 2007, 151(3):293-298
186. Kelly G. Inulin-type prebiotics: a review (Part 2). Altern Med Rev 2009, 14(1):36-55
187. Roberfroid M.B., Delzenne N.M. Dietary fructans. Annu Rev Nutr 1998, 18:117-143
188. Delgado G.T.C., Tamashiro W.M.S.C., Pastore G.M. Immunomodulatory effects of fructans. Food Res Int 2010, 43(5):1231-1236
189. Qiang X., YongLie C., QianBing W. Health benefit application of functional oligosaccharides. Carbohydr Polym 2009, 77(3):435-441
190. De Preter V., Hamer H.M., Windey K., Verbeke K. The impact of pre-and/or probiotics on human colonic metabolism: does it affect human health?. Mol Nutr Food Res 2011, 55(1):46-57
191. Yen C.H., Kuo Y.W., Tseng Y.H., Lee M.C., Chen H.L. Beneficial effects of fructo-oligosaccharides supplementation on fecal bifidobacteria and index of peroxidation status in constipated nursing-home residents-A placebo-controlled, diet-controlled trial. Nutrition 2011, 27(3):323-328
192. Official Journal of the European Union Regulation (EC) No 1924/2006 of the European Parliament and of the Council of 20 December 2006 on nutrition and health claims made on foods 2012, L404/9-L404/25. (acceded in 19.03.2014). http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32006R1924%26from=EN
193. FDA Significant dates in U.S. Food and Drug Law History 2012, (acceded in 19.03.2014). http://www.fda.gov/aboutfda/whatwedo/history/milestones/ucm128305.htm
194. Official Journal of the European Union Regulation (EC) No 432/2012 of the European Parliament and of the Council of 20 December 2006 establishing a list of permitted health claims made on foods, other than those referring to the reduction of disease risk and to children's development and health 2012, L136/1-L136/40. (acceded in 21.03.2014). http://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:32006R1924%26from=EN
195. CODEX STAN 1-1985 Codex General Standard for the labelling of prepackaged foods 2010, Codex Alimentarius. Joint FAO/WHO Food Standards Programme, vol. 66, (acceded in 21.03.2014). http://www.codexalimentarius.org/download/standards/32/CXS_001e.pdf
196. FAO Compendium of food additive specifications 2013, (acceded in 19.03.2014). http://www.fao.org/food/food-safety-quality/scientific-advice/jecfa/jecfa-additives/en/
197. FDA Food additives permitted for direct addition to food for human consumption. Food Drugs 2013, (acceded in 19.03.2014). http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=172
198. FDA Determining the regulatory status of a food ingredient. Ingredients Packag Labeling 2013, (acceded in 19.03.2014). http://www.fda.gov/Food/IngredientsPackagingLabeling/FoodAdditivesIngredients/ucm228269.htm
199. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS) Guidance for submission for food additive evaluations. EFSA J 2012, 60(7):2760-2820. (acceded in 26.03.2014). http://www.efsa.europa.eu/en/efsajournal/doc/2760.pdf