Production of galacto-oligosaccharides by the β-galactosidase from kluyveromyces lactis: Comparative analysis of permeabilized cells versus soluble enzyme

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 19, 2011, Pages 10477-10484

  Rodriguez Colinas, Barbara ^a   De Abreu, Miguel A ^b   Fernandez Arrojo, Lucia ^a   De Beer, Roseri ^a   Poveda, Ana ^b   Jimenez Barbero, Jesus ^c   Haltrich, Dietmar ^d   Ballesteros Olmo, Antonio O ^a   Fernandez Lobato, Maria ^b   Plou, Francisco J ^a  

^a INSTITUTO DE CATÁLISIS Y PETROLEOQUÍMICA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^d UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

Author keywords

galactosidase; galacto oligosaccharides; glycosidase; oligosaccharides; prebiotics; transglycosylation

Indexed keywords

GALACTO-OLIGOSACCHARIDES; GALACTOSIDASES; GLYCOSIDASES; PREBIOTICS; TRANSGLYCOSYLATION;

CARBOHYDRATES; CELLS; ENZYMES; ETHANOL;

OLIGOSACCHARIDES;

BETA GALACTOSIDASE; GALACTOSE; OLIGOSACCHARIDE;

ARTICLE; BIOSYNTHESIS; CELL MEMBRANE PERMEABILITY; COMPARATIVE STUDY; ENZYMOLOGY; KLUYVEROMYCES; METABOLISM; SOLUBILITY;

BETA-GALACTOSIDASE; CELL MEMBRANE PERMEABILITY; GALACTOSE; KLUYVEROMYCES; OLIGOSACCHARIDES; SOLUBILITY;

KLUYVEROMYCES LACTIS;

EID: 80053491443     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf2022012     Document Type: Article

References (46)

1. Adam, A. C.; Rubio-Texeira, M.; Polaina, J. Lactose: the milk sugar from a biotechnological perspective Crit. Rev. Food Sci. 2004, 44, 553-557 (Pubitemid 40536483)
2. Hsu, C. A.; Lee, S. L.; Chou, C. C. Enzymatic production of galactooligosaccharides by β-galactosidase from Bifidobacterium longum BCRC 15708 J. Agric. Food Chem. 2007, 55, 2225-2230 (Pubitemid 46556209)
3. Matella, N. J.; Dolan, K. D.; Lee, Y. S. Comparison of galactooligosaccharide production in free-enzyme ultrafiltration and in immobilized-enzyme systems J. Food Sci. 2006, 71, C363-C368
4. Seibel, J.; Jordening, H. J.; Buchholz, K. Glycosylation with activated sugars using glycosyltransferases and transglycosidases Biocatal. Biotransform. 2006, 24, 311-342 (Pubitemid 44615045)
5. Bojarova, P.; Kren, V. Glycosidases: a key to tailored carbohydrates Trends Biotechnol. 2009, 27, 199-209
6. Desmet, T.; Soetaert, W. Enzymatic glycosyl transfer: mechanisms and applications Biocatal. Biotransform. 2011, 29, 1-18
7. Torres, D. P.; Goncalves, M.; Teixeira, J. A.; Rodrigues, L. R. Galacto-oligosaccharides: production, properties, applications, and significance as prebiotics Compr. Rev. Food Sci. F 2010, 9, 438-454
8. Park, A. R.; Oh, D. K. Galacto-oligosaccharide production using microbial β-galactosidase: current state and perspectives Appl. Microbiol. Biotechnol. 2010, 85, 1279-1286
9. Splechtna, B.; Nguyen, T. H.; Steinbock, M.; Kulbe, K. D.; Lorenz, W.; Haltrich, D. Production of prebiotic galacto-oligosaccharides from lactose using β-galactosidases from Lactobacillus re teri J. Agric. Food Chem. 2006, 54, 4999-5006 (Pubitemid 44140894)
10. Maischberger, T.; Leitner, E.; Nitisinprasert, S.; Juajun, O.; Yamabhai, M.; Nguyen, T. H.; Haltrich, D. β-Galactosidase from Lactobacillus pentosus: purification, characterization and formation of galacto- oligosaccharides Biotechnol. J. 2010, 5, 838-847
11. Iqbal, S.; Nguyen, T. H.; Nguyen, T. T.; Maischberger, T.; Haltrich, D. β-Galactosidase from Lactobacillus plantarum WCFS1: biochemical characterization and formation of prebiotic galacto-oligosaccharides Carbohydr. Res. 2010, 345, 1408-1416
12. Shadid, R.; Haarman, M.; Knol, J.; Theis, W.; Beermann, C.; Rjosk-Dendorfer, D.; Schendel, D. J.; Koletzko, B. V.; Krauss-Etschmann, S. Effects of galactooligosaccharide and long-chain fructooligosaccharide supplementation during pregnancy on maternal and neonatal microbiota and immunity - a randomized, double-blind, placebo-controlled study Am. J. Clin. Nutr. 2007, 86, 1426-1437 (Pubitemid 350126248)
13. Rastall, R. A.; Gibson, G. R.; Gill, H. S.; Guarner, F.; Klaenhammer, T. R.; Pot, B.; Reid, G.; Rowland, I. R.; Sanders, M. E. Modulation of the microbial ecology of the human colon by probiotics, prebiotics and synbiotics to enhance human health: an overview of enabling science and potential applications FEMS Microbiol. Ecol. 2005, 52, 145-152 (Pubitemid 40386989)
14. Gosling, A.; Stevens, G. W.; Barber, A. R.; Kentish, S. E.; Gras, S. L. Recent advances refining galactooligosaccharide production from lactose Food Chem. 2010, 121, 307-318
15. Martinez-Villaluenga, C.; Cardelle-Cobas, A.; Corzo, N.; Olano, A.; Villamiel, M. Optimization of conditions for galactooligosaccharide synthesis during lactose hydrolysis by β-galactosidase from Kluyveromyces lactis (Lactozym 3000 L HP G) Food Chem. 2008, 107, 258-264 (Pubitemid 350011129)
16. Chockchaisawasdee, S.; Athanasopoulos, V. I.; Niranjan, K.; Rastall, R. A. Synthesis of galacto-oligosaccharide from lactose using β-galactosidase from Kluyveromyces lactis: studies on batch and continuous UF membrane-fitted bioreactors Biotechnol. Bioeng. 2005, 89, 434-443 (Pubitemid 40288904)
17. Maugard, T.; Gaunt, D.; Legoy, M. D.; Besson, T. Microwave-assisted synthesis of galacto-oligosaccharides from lactose with immobilized β-galactosidase from Kluyveromyces lactis Biotechnol. Lett. 2003, 25, 623-629 (Pubitemid 36536565)
18. Pinho, J. M. R.; Passos, F. M. L. Solvent extraction of β-galactosidase from Kluyveromyces lactis yields a stable and highly active enzyme preparation J. Food Biochem. 2011, 35, 323-336
19. Pal, A.; Pal, V.; Ramana, K. V.; Bawa, A. S. Biochemical studies of β-galactosidase from Kluyveromyces lactis J. Food Sci. Technol. 2009, 46, 217-220
20. Zhou, Q. Z. K.; Chen, X. D. Effects of temperature and pH on the catalytic activity of the immobilized β-galactosidase from Kluyveromyces lactis Biochem. Eng. J. 2001, 9, 33-40 (Pubitemid 33029190)
21. Zhou, Q. Z.; Chen, X. D.; Li, X. Kinetics of lactose hydrolysis by β-galactosidase of Kluyveromyces lactis immobilized on cotton fabric Biotechnol. Bioeng. 2003, 81, 127-133 (Pubitemid 36077289)
22. Siso, M. I. G.; Cerdan, E.; Picos, M. A. F.; Ramil, E.; Belmonte, E. R.; Torres, A. R. Permeabilization of Kluyveromyces lactis cells for milk whey saccharification: a comparison of different treatments Biotechnol. Tech. 1992, 6, 289-292
23. Fontes, E. A. F.; Passos, F. M. L.; Passos, F. J. V. A mechanistical mathematical model to predict lactose hydrolysis by β-galactosidase in a permeabilized cell mass of Kluyveromyces lactis: validity and sensitivity analysis Process Biochem. 2001, 37, 267-274 (Pubitemid 32928925)
24. Kondo, A.; Liu, Y.; Furuta, M.; Fujita, Y.; Matsumoto, T.; Fukuda, H. Preparation of high activity whole cell biocatalyst by permeabilization of recombinant flocculent yeast with alcohol Enzyme Microbial Technol. 2000, 27, 806-811
25. Boon, M. A.; Janssen, A. E. M.; Van't Riet, K. Effect of temperature and enzyme origin on the enzymatic synthesis of oligosaccharides Enzyme Microbial Technol. 2000, 26, 271-281
26. Prenosil, J. E.; Stuker, E.; Bourne, J. R. Formation of oligosaccharides during enzymatic lactose hydrolysis and their importance in a whey hydrolysis process: part II. Experimental Biotechnol. Bioeng. 1987, 30, 1026-1031 (Pubitemid 18547150)
27. Manera, A. P.; De Almeida, F. A.; Rodrigues, M. I.; Kalil, S. J.; Filho, F. M. Galacto-oligosaccharides production using permeabilized cells of Kluyveromyces marxianus Int. J. Food Eng. 2010, 6, 1-13
28. Genari, A. N.; Passos, F. V.; Passos, F. M. L. Configuration of a bioreactor for milk lactose hydrolysis J. Dairy Sci. 2003, 86, 2783-2789 (Pubitemid 39066994)
29. Panesar, R.; Panesar, P. S.; Singh, R. S.; Kennedy, J. F.; Bera, M. B. Production of lactose-hydrolyzed milk using ethanol permeabilized yeast cells Food Chem. 2007, 101, 786-790 (Pubitemid 44333209)
30. Lee, Y. J.; Kim, C. S.; Oh, D. K. Lactulose production by β-galactosidase in permeabilized cells of Kluyveromyces lactis Appl. Microbiol. Biotechnol. 2004, 64, 787-793 (Pubitemid 38918141)
31. Panesar, R.; Panesar, P. S.; Singh, R. S.; Kennedy, J. F. Hydrolysis of milk lactose in a packed bed reactor system using immobilized yeast cells J. Chem. Technol. Biotechnol. 2011, 86, 42-46
32. Stred'ansky, M.; Tomaska, M.; Sturdik, E.; Kremnicky, L. Optimization of β-galactosidase extraction from Kluyveromyces marxianus Enzyme Microbial Technol. 1993, 15, 1063-1065
33. Puri, M.; Gupta, S.; Pahuja, P.; Kaur, A.; Kanwar, J. R.; Kennedy, J. F. Cell disruption optimization and covalent immobilization of β-d -galactosidase from Kluyveromyces marxianus YW-1 for lactose hydrolysis in milk Appl. Biochem. Biotechnol. 2010, 160, 98-108
34. Schwab, C.; Lee, V.; Sorensen, K. I.; Ganzle, M. G. Production of galactooligosaccharides and heterooligosaccharides with disrupted cell extracts and whole cells of lactic acid bacteria and bifidobacteria Int. Dairy J. 2011, 21, 748-754
35. Matioli, G.; De Moraes, F. F.; Zanin, G. M. Operational stability and kinetics of lactose hydrolysis by β-galactosidase from Kluyveromyces fragilis Acta Sci. Health Sci. 2003, 25, 7-12 (Pubitemid 41113287)
36. Prasad, S.; Roy, I. Effect of disaccharides on the stabilization of bovine trypsin against detergent and autolysis Biotechnol. Prog. 2010, 26, 627-635
37. Ghazi, I.; Fernandez-Arrojo, L.; Garcia-Arellano, H.; Ferrer, M.; Ballesteros, A.; Plou, F. J. Purification and kinetic characterization of a fructosyltransferase from Aspergillus aculeatus J. Biotechnol. 2007, 128, 204-211 (Pubitemid 44960523)
38. Plou, F. J.; Martin, M. T.; Gomez de Segura, A.; Alcalde, M.; Ballesteros, A. Glucosyltransferases acting on starch or sucrose for the synthesis of oligosaccharides Can. J. Chem. 2002, 80, 743-752 (Pubitemid 34988975)
39. Plou, F. J.; Gomez de Segura, A.; Ballesteros, A. Application of glycosidases and transglycosidases for the synthesis of oligosaccharides. In Industrial Enzymes: Structure, Function and Application; Polaina, J.; MacCabe, A. P., Eds.; Springer: New York, 2007; pp 141-157.
40. Buchholz, K.; Kasche, V.; Bornscheuer, U. T. Biocatalysts and Enzyme Technology; Wiley-VCH Verlag: Weinheim, Germany, 2005.
41. Cheng, C. C.; Yu, M. C.; Cheng, T. C.; Sheu, D. C.; Duan, K. J.; Tai, W. L. Production of high-content galacto-oligosaccharide by enzyme catalysis and fermentation with Kluyveromyces marxianus Biotechnol. Lett. 2006, 28, 793-797
42. Rabiu, B. A.; Jay, A. J.; Gibson, G. R.; Rastall, R. A. Synthesis and fermentation properties of novel galacto-oligosaccharides by β-galactosidases from Bifidobacterium species Appl. Environ. Microbiol. 2001, 67, 2526-2530 (Pubitemid 33639722)
43. Hansson, T.; Adlercreutz, P. Optimization of galactooligosaccharide production from lactose using β-glycosidases from hyperthermophiles Food Biotechnol. 2001, 15, 79-97 (Pubitemid 34152499)
44. Ghazi, I.; Fernandez-Arrojo, L.; Gomez de Segura, A.; Alcalde, M.; Plou, F. J.; Ballesteros, A. Beet sugar syrup and molasses as low-cost feedstock for the enzymatic production of fructo-oligosaccharides J. Agric. Food Chem. 2006, 54, 2964-2968
45. Alvaro-Benito, M.; De Abreu, M.; Fernandez-Arrojo, L.; Plou, F. J.; Jimenez-Barbero, J.; Ballesteros, A.; Polaina, J.; Fernandez-Lobato, M. Characterization of a β-fructofuranosidase from Schwanniomyces occidentalis with transfructosylating activity yielding the prebiotic 6-kestose J. Biotechnol. 2007, 132, 75-81 (Pubitemid 47503384)
46. Rodriguez-Alegria, M. E.; Enciso-Rodriguez, A.; Ortiz-Soto, M. E.; Cassani, J.; Olvera, C.; Lopez-Munguia, A. Fructooligosaccharide production by a truncated Leuconostoc citreum inulosucrase mutant Biocatal. Biotransform. 2010, 28, 51-59