-
1
-
-
70349859881
-
DNA damage, aging, and cancer
-
J. H. Hoeijmakers: DNA damage, aging, and cancer. N Engl J Med, 361(15), 1475-85 (2009) DOI: 10.1056/NEJMra0804615
-
(2009)
N Engl J Med
, vol.361
, Issue.15
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
2
-
-
38049125552
-
The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases
-
S. D. McCulloch and T. A. Kunkel: The fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerases. Cell Res, 18(1), 148-61 (2008) DOI: 10.1038/cr.2008.4
-
(2008)
Cell Res
, vol.18
, Issue.1
, pp. 148-161
-
-
McCulloch, S.D.1
Kunkel, T.A.2
-
3
-
-
78649336706
-
The DNA damage response: Making it safe to play with knives
-
A. Ciccia and S. J. Elledge: The DNA damage response: making it safe to play with knives. Mol Cell, 40(2), 179-204 (2010) DOI: 10.1016/j.molcel.2010.09.019
-
(2010)
Mol Cell
, vol.40
, Issue.2
, pp. 179-204
-
-
Ciccia, A.1
Elledge, S.J.2
-
4
-
-
0035472817
-
Direct and indirect effects of UV radiation on DNA and its components
-
J. L. Ravanat, T. Douki and J. Cadet: Direct and indirect effects of UV radiation on DNA and its components. J Photochem Photobiol B, 63(1-3), 88-102 (2001) DOI: 10.1016/S1011-1344(01)00206-8
-
(2001)
J Photochem Photobiol B
, vol.63
, Issue.1-3
, pp. 88-102
-
-
Ravanat, J.L.1
Douki, T.2
Cadet, J.3
-
5
-
-
0024195429
-
DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability
-
J. F. Ward: DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability. Prog Nucleic Acid Res Mol Biol, 35, 95-125 (1988) DOI: 10.1016/S0079-6603(08)60611-X
-
(1988)
Prog Nucleic Acid Res Mol Biol
, vol.35
, pp. 95-125
-
-
Ward, J.F.1
-
6
-
-
84856866918
-
DNA damage induces reactive oxygen species generation through the H2AX-nox1/Rac1 pathway
-
M. A. Kang, E. Y. So, A. L. Simons, D. R. Spitz and T. Ouchi: DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway. Cell Death Dis, 3, e249 (2012) DOI: 10.1038/cddis.2011.134
-
(2012)
Cell Death Dis
, vol.3
, pp. e249
-
-
Kang, M.A.1
So, E.Y.2
Simons, A.L.3
Spitz, D.R.4
Ouchi, T.5
-
7
-
-
36949013395
-
ATM and the mre11 complex combine to recognize and signal DNA double-strand breaks
-
M. F. Lavin: ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene, 26(56), 7749-58 (2007) DOI: 10.1038/sj.onc.1210880
-
(2007)
Oncogene
, vol.26
, Issue.56
, pp. 7749-7758
-
-
Lavin, M.F.1
-
8
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage
-
J. Falck, J. Coates and S. P. Jackson: Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage. Nature, 434(7033), 605-11 (2005) DOI: 10.1038/nature03442
-
(2005)
Nature
, vol.434
, Issue.7033
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
9
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the mre11-rad50-nbs1 complex
-
J. H. Lee and T. T. Paull: ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science, 308(5721), 551-4 (2005) DOI: 10.1126/science.1108297
-
(2005)
Science
, vol.308
, Issue.5721
, pp. 551-554
-
-
Lee, J.H.1
Paull, T.T.2
-
10
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
T. Uziel, Y. Lerenthal, L. Moyal, Y. Andegeko, L. Mittelman and Y. Shiloh: Requirement of the MRN complex for ATM activation by DNA damage. EMBO J, 22(20), 5612-21 (2003) DOI: 10.1093/emboj/cdg541
-
(2003)
EMBO J
, vol.22
, Issue.20
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
11
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
D. Cortez, S. Guntuku, J. Qin and S. J. Elledge: ATR and ATRIP: partners in checkpoint signaling. Science, 294(5547), 1713-6 (2001) DOI: 10.1126/science.1065521
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
12
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPAssDNA complexes
-
L. Zou and S. J. Elledge: Sensing DNA damage through ATRIP recognition of RPAssDNA complexes. Science, 300(5625), 1542-8 (2003) DOI: 10.1126/science.1083430
-
(2003)
Science
, vol.300
, Issue.5625
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
13
-
-
33751419716
-
Surviving the breakup: The DNA damage checkpoint
-
doi:10.1146/annurev.genet.40.051206.105231
-
J. C. Harrison and J. E. Haber: Surviving the breakup: the DNA damage checkpoint. Annu Rev Genet, 40, 209-35 (2006) DOI: 10.1.146/annurev.genet.40.0.51206.1.05231 DOI: 10.1146/annurev.genet.40.051206.105231
-
(2006)
Annu Rev Genet
, vol.40
, pp. 209-235
-
-
Harrison, J.C.1
Haber, J.E.2
-
14
-
-
36749022214
-
The DNA damage response: Ten years after
-
J. W. Harper and S. J. Elledge: The DNA damage response: ten years after. Mol Cell, 28(5), 739-45 (2007) DOI: 10.1016/j.molcel.2007.11.015
-
(2007)
Mol Cell
, vol.28
, Issue.5
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
15
-
-
0038418869
-
Chk1 and chk2 kinases in checkpoint control and cancer
-
J. Bartek and J. Lukas: Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell, 3(5), 421-9 (2003) DOI: 10.1016/S1535-6108(03)00110-7
-
(2003)
Cancer Cell
, vol.3
, Issue.5
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
16
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
-
D. Cortez, Y. Wang, J. Qin and S. J. Elledge: Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science, 286(5442), 1162-6 (1999) DOI: 10.1126/science.286.5442.1162
-
(1999)
Science
, vol.286
, Issue.5442
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
17
-
-
0036500555
-
Involvement of the cohesin protein, smc1, in atm-dependent and independent responses to DNA damage
-
S. T. Kim, B. Xu and M. B. Kastan: Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev, 16(5), 560-70 (2002) DOI: 10.1101/gad.970602
-
(2002)
Genes Dev
, vol.16
, Issue.5
, pp. 560-570
-
-
Kim, S.T.1
Xu, B.2
Kastan, M.B.3
-
18
-
-
3242890575
-
Mammalian cell cycle checkpoints: Signalling pathways and their organization in space and time
-
J. Lukas, C. Lukas and J. Bartek: Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. DNA Repair (Amst), 3(8-9), 997-1007 (2004) DOI: 10.1016/j.dnarep.2004.03.006
-
(2004)
DNA Repair (Amst)
, vol.3
, Issue.8-9
, pp. 997-1007
-
-
Lukas, J.1
Lukas, C.2
Bartek, J.3
-
19
-
-
0141757479
-
DNA damage checkpoint control in cells exposed to ionizing radiation
-
G. Iliakis, Y. Wang, J. Guan and H. Wang: DNA damage checkpoint control in cells exposed to ionizing radiation. Oncogene, 22(37), 5834-47 (2003) DOI: 10.1038/sj.onc.1206682
-
(2003)
Oncogene
, vol.22
, Issue.37
, pp. 5834-5847
-
-
Iliakis, G.1
Wang, Y.2
Guan, J.3
Wang, H.4
-
20
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
M. B. Kastan and J. Bartek: Cell-cycle checkpoints and cancer. Nature, 432(7015), 316-23 (2004) DOI: 10.1038/nature03097
-
(2004)
Nature
, vol.432
, Issue.7015
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
21
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
B. B. Zhou and S. J. Elledge: The DNA damage response: putting checkpoints in perspective. Nature, 408(6811), 433-9 (2000) DOI: 10.1038/35044005
-
(2000)
Nature
, vol.408
, Issue.6811
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
22
-
-
39749151090
-
DNA damage and repair: From molecular mechanisms to health implications
-
F. Altieri, C. Grillo, M. Maceroni and S. Chichiarelli: DNA damage and repair: from molecular mechanisms to health implications. Antioxid Redox Signal, 10(5), 891-937 (2008) DOI: 10.1089/ars.2007.1830
-
(2008)
Antioxid Redox Signal
, vol.10
, Issue.5
, pp. 891-937
-
-
Altieri, F.1
Grillo, C.2
Maceroni, M.3
Chichiarelli, S.4
-
23
-
-
0035093737
-
DNA doublestrand breaks: Signaling, repair and the cancer connection
-
K. K. Khanna and S. P. Jackson: DNA doublestrand breaks: signaling, repair and the cancer connection. Nat Genet, 27(3), 247-54 (2001) DOI: 10.1038/85798
-
(2001)
Nat Genet
, vol.27
, Issue.3
, pp. 247-254
-
-
Khanna, K.K.1
Jackson, S.P.2
-
24
-
-
0035289717
-
Chromosomal stability and the DNA double-stranded break connection
-
D. C. van Gent, J. H. Hoeijmakers and R. Kanaar: Chromosomal stability and the DNA double-stranded break connection. Nat Rev Genet, 2(3), 196-206 (2001) DOI: 10.1038/35056049
-
(2001)
Nat Rev Genet
, vol.2
, Issue.3
, pp. 196-206
-
-
Van Gent, D.C.1
Hoeijmakers, J.H.2
Kanaar, R.3
-
25
-
-
70350088548
-
Mechanisms of double-strand break repair in somatic mammalian cells
-
A. J. Hartlerode and R. Scully: Mechanisms of double-strand break repair in somatic mammalian cells. Biochem J, 423(2), 157-68 (2009) DOI: 10.1042/BJ20090942
-
(2009)
Biochem J
, vol.423
, Issue.2
, pp. 157-168
-
-
Hartlerode, A.J.1
Scully, R.2
-
26
-
-
62349103878
-
DNA repair in mammalian cells: DNA double-strand break repair: How to fix a broken relationship
-
B. Pardo, B. Gomez-Gonzalez and A. Aguilera: DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship. Cell Mol Life Sci, 66(6), 1039-56 (2009) DOI: 10.1007/s00018-009-8740-3
-
(2009)
Cell Mol Life Sci
, vol.66
, Issue.6
, pp. 1039-1056
-
-
Pardo, B.1
Gomez-Gonzalez, B.2
Aguilera, A.3
-
27
-
-
38049173021
-
Homologous recombination in DNA repair and DNA damage tolerance
-
X. Li and W. D. Heyer: Homologous recombination in DNA repair and DNA damage tolerance. Cell Res, 18(1), 99-113 (2008) DOI: 10.1038/cr.2008.1
-
(2008)
Cell Res
, vol.18
, Issue.1
, pp. 99-113
-
-
Li, X.1
Heyer, W.D.2
-
28
-
-
51849121635
-
DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells
-
Z. Mao, M. Bozzella, A. Seluanov and V. Gorbunova: DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells. Cell Cycle, 7(18), 2902-6 (2008) DOI: 10.4161/cc.7.18.6679
-
(2008)
Cell Cycle
, vol.7
, Issue.18
, pp. 2902-2906
-
-
Mao, Z.1
Bozzella, M.2
Seluanov, A.3
Gorbunova, V.4
-
29
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
M. R. Lieber: The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu Rev Biochem, 79, 181-211 (2010) DOI: 10.1146/annurev. biochem.052308.093131
-
(2010)
Annu Rev Biochem
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
30
-
-
84882450932
-
Various modes of cell death induced by DNA damage
-
O. Surova and B. Zhivotovsky: Various modes of cell death induced by DNA damage. Oncogene, 32(33), 3789-97 (2013) DOI: 10.1038/onc.2012.556
-
(2013)
Oncogene
, vol.32
, Issue.33
, pp. 3789-3797
-
-
Surova, O.1
Zhivotovsky, B.2
-
31
-
-
50549218525
-
The limited in vitro lifetime of human diploid cell strains
-
L. Hayflick: The Limited in vitro Lifetime of Human Diploid Cell Strains. Exp Cell Res, 37, 614-36 (1965) DOI: 10.1016/0014-4827(65)90211-9
-
(1965)
Exp Cell Res
, vol.37
, pp. 614-636
-
-
Hayflick, L.1
-
32
-
-
0344622606
-
The serial cultivation of human diploid cell strains
-
L. Hayflick and P. S. Moorhead: The serial cultivation of human diploid cell strains. Exp Cell Res, 25, 585-621 (1961) DOI: 10.1016/0014-4827(61)90192-6
-
(1961)
Exp Cell Res
, vol.25
, pp. 585-621
-
-
Hayflick, L.1
Moorhead, P.S.2
-
33
-
-
33747192833
-
Cellular senescence in naevi and immortalisation in melanoma: A role for p16?
-
V. C. Gray-Schopfer, S. C. Cheong, H. Chong, J. Chow, T. Moss, Z. A. Abdel-Malek, R. Marais, D. Wynford-Thomas and D. C. Bennett: Cellular senescence in naevi and immortalisation in melanoma: a role for p16? Br J Cancer, 95(4), 496-505 (2006) DOI: 10.1038/sj.bjc.6603283
-
(2006)
Br J Cancer
, vol.95
, Issue.4
, pp. 496-505
-
-
Gray-Schopfer, V.C.1
Cheong, S.C.2
Chong, H.3
Chow, J.4
Moss, T.5
Abdel-Malek, Z.A.6
Marais, R.7
Wynford-Thomas, D.8
Bennett, D.C.9
-
34
-
-
33845269825
-
Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication
-
R. Di Micco, M. Fumagalli, A. Cicalese, S. Piccinin, P. Gasparini, C. Luise, C. Schurra, M. Garre, P. G. Nuciforo, A. Bensimon, R. Maestro, P. G. Pelicci and F. d'Adda di Fagagna: Oncogene-induced senescence is a DNA damage response triggered by DNA hyper-replication. Nature, 444(7119), 638-42 (2006) DOI: 10.1038/nature05327
-
(2006)
Nature
, vol.444
, Issue.7119
, pp. 638-642
-
-
Di Micco, R.1
Fumagalli, M.2
Cicalese, A.3
Piccinin, S.4
Gasparini, P.5
Luise, C.6
Schurra, C.7
Garre, M.8
Nuciforo, P.G.9
Bensimon, A.10
Maestro, R.11
Pelicci, P.G.12
D'Adda Di-Fagagna, F.13
-
35
-
-
33748422079
-
Oncogeneinduced cell senescence-halting on the road to cancer
-
W. J. Mooi and D. S. Peeper: Oncogeneinduced cell senescence-halting on the road to cancer. N Engl J Med, 355(10), 1037-46 (2006) DOI: 10.1056/NEJMra062285
-
(2006)
N Engl J Med
, vol.355
, Issue.10
, pp. 1037-1046
-
-
Mooi, W.J.1
Peeper, D.S.2
-
36
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of ptendeficient tumorigenesis
-
Z. Chen, L. C. Trotman, D. Shaffer, H. K. Lin, Z. A. Dotan, M. Niki, J. A. Koutcher, H. I. Scher, T. Ludwig, W. Gerald, C. Cordon-Cardo and P. P. Pandolfi: Crucial role of p53-dependent cellular senescence in suppression of Ptendeficient tumorigenesis. Nature, 436(7051), 725-30 (2005) DOI: 10.1038/nature03918
-
(2005)
Nature
, vol.436
, Issue.7051
, pp. 725-730
-
-
Chen, Z.1
Trotman, L.C.2
Shaffer, D.3
Lin, H.K.4
Dotan, Z.A.5
Niki, M.6
Koutcher, J.A.7
Scher, H.I.8
Ludwig, T.9
Gerald, W.10
Cordon-Cardo, C.11
Pandolfi, P.P.12
-
37
-
-
63249089044
-
Rb regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation
-
1 No DOI Found
-
A. Shamma, Y. Takegami, T. Miki, S. Kitajima, M. Noda, T. Obara, T. Okamoto and C. Takahashi: Rb Regulates DNA damage response and cellular senescence through E2F-dependent suppression of N-ras isoprenylation. Cancer Cell, 15(4), 255-69 (2009)1 No DOI Found
-
(2009)
Cancer Cell
, vol.15
, Issue.4
, pp. 255-269
-
-
Shamma, A.1
Takegami, Y.2
Miki, T.3
Kitajima, S.4
Noda, M.5
Obara, T.6
Okamoto, T.7
Takahashi, C.8
-
38
-
-
67651148274
-
Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling
-
C. Gewinner, Z. C. Wang, A. Richardson, J. Teruya-Feldstein, D. Etemadmoghadam, D. Bowtell, J. Barretina, W. M. Lin, L. Rameh, L. Salmena, P. P. Pandolfi and L. C. Cantley: Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling. Cancer Cell, 16(2), 115-25 (2009) DOI: 10.1016/j.ccr.2009.06.006
-
(2009)
Cancer Cell
, vol.16
, Issue.2
, pp. 115-125
-
-
Gewinner, C.1
Wang, Z.C.2
Richardson, A.3
Teruya-Feldstein, J.4
Etemadmoghadam, D.5
Bowtell, D.6
Barretina, J.7
Lin, W.M.8
Rameh, L.9
Salmena, L.10
Pandolfi, P.P.11
Cantley, L.C.12
-
39
-
-
33749020871
-
P53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts
-
J. G. Jackson and O. M. Pereira-Smith: p53 is preferentially recruited to the promoters of growth arrest genes p21 and GADD45 during replicative senescence of normal human fibroblasts. Cancer Res, 66(17), 8356-60 (2006) DOI: 10.1158/0008-5472.CAN-06-1752
-
(2006)
Cancer Res
, vol.66
, Issue.17
, pp. 8356-8360
-
-
Jackson, J.G.1
Pereira-Smith, O.M.2
-
40
-
-
0242329884
-
P53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage
-
J. M. Espinosa, R. E. Verdun and B. M. Emerson: p53 functions through stress- and promoter-specific recruitment of transcription initiation components before and after DNA damage. Mol Cell, 12(4), 1015-27 (2003) DOI: 10.1016/S1097-2765(03)00359-9
-
(2003)
Mol Cell
, vol.12
, Issue.4
, pp. 1015-1027
-
-
Espinosa, J.M.1
Verdun, R.E.2
Emerson, B.M.3
-
41
-
-
28244499304
-
Identification of differentially expressed proteins in senescent human embryonic fibroblasts
-
I. P. Trougakos, A. Saridaki, G. Panayotou and E. S. Gonos: Identification of differentially expressed proteins in senescent human embryonic fibroblasts. Mech Ageing Dev, 127(1), 88-92 (2006) DOI: 10.1016/j.mad.2005.08.009
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.1
, pp. 88-92
-
-
Trougakos, I.P.1
Saridaki, A.2
Panayotou, G.3
Gonos, E.S.4
-
42
-
-
84874418442
-
The convergence of radiation and immunogenic cell death signaling pathways
-
E. B. Golden, I. Pellicciotta, S. Demaria, M. H. Barcellos-Hoff and S. C. Formenti: The convergence of radiation and immunogenic cell death signaling pathways. Front Oncol, 2, 88 (2012) DOI: 10.3389/fonc.2012.00088
-
(2012)
Front Oncol
, vol.2
, pp. 88
-
-
Golden, E.B.1
Pellicciotta, I.2
Demaria, S.3
Barcellos-Hoff, M.H.4
Formenti, S.C.5
-
43
-
-
0029047362
-
A biomarker that identifies senescent human cells in culture and in aging skin in vivo
-
G. P. Dimri, X. Lee, G. Basile, M. Acosta, G. Scott, C. Roskelley, E. E. Medrano, M. Linskens, I. Rubelj, O. Pereira-Smith and et al.: A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci U S A, 92(20), 9363-7 (1995) DOI: 10.1073/pnas.92.20.9363
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, Issue.20
, pp. 9363-9367
-
-
Dimri, G.P.1
Lee, X.2
Basile, G.3
Acosta, M.4
Scott, G.5
Roskelley, C.6
Medrano, E.E.7
Linskens, M.8
Rubelj, I.9
Pereira-Smith, O.10
-
44
-
-
33644692330
-
Cellular senescence in aging primates
-
U. Herbig, M. Ferreira, L. Condel, D. Carey and J. M. Sedivy: Cellular senescence in aging primates. Science, 311(5765), 1257 (2006) DOI: 10.1126/science.1122446
-
(2006)
Science
, vol.311
, Issue.5765
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
45
-
-
78651104478
-
DNA-SCARS: Distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion
-
F. Rodier, D. P. Munoz, R. Teachenor, V. Chu, O. Le, D. Bhaumik, J. P. Coppe, E. Campeau, C. M. Beausejour, S. H. Kim, A. R. Davalos and J. Campisi: DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion. J Cell Sci, 124(Pt 1), 68-81 (2011) DOI: 10.1242/jcs.071340
-
(2011)
J Cell Sci
, vol.124
, pp. 68-81
-
-
Rodier, F.1
Munoz, D.P.2
Teachenor, R.3
Chu, V.4
Le, O.5
Bhaumik, D.6
Coppe, J.P.7
Campeau, E.8
Beausejour, C.M.9
Kim, S.H.10
Davalos, A.R.11
Campisi, J.12
-
46
-
-
57649149333
-
Classification of cell death: Recommendations of the nomenclature committee on cell death 2009
-
and D. Nomenclature Committee on Cell
-
G. Kroemer, L. Galluzzi, P. Vandenabeele, J. Abrams, E. S. Alnemri, E. H. Baehrecke, M. V. Blagosklonny, W. S. El-Deiry, P. Golstein, D. R. Green, M. Hengartner, R. A. Knight, S. Kumar, S. A. Lipton, W. Malorni, G. Nunez, M. E. Peter, J. Tschopp, J. Yuan, M. Piacentini, B. Zhivotovsky, G. Melino and D. Nomenclature Committee on Cell: Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ, 16(1), 3-11 (2009) DOI: 10.1038/cdd.2008.150
-
(2009)
Cell Death Differ
, vol.16
, Issue.1
, pp. 3-11
-
-
Kroemer, G.1
Galluzzi, L.2
Vandenabeele, P.3
Abrams, J.4
Alnemri, E.S.5
Baehrecke, E.H.6
Blagosklonny, M.V.7
El-Deiry, W.S.8
Golstein, P.9
Green, D.R.10
Hengartner, M.11
Knight, R.A.12
Kumar, S.13
Lipton, S.A.14
Malorni, W.15
Nunez, G.16
Peter, M.E.17
Tschopp, J.18
Yuan, J.19
Piacentini, M.20
Zhivotovsky, B.21
Melino, G.22
more..
-
47
-
-
84857995837
-
Oxidative stress induces an ATM-independent senescence pathway through p38 MAPKmediated lamin B1 accumulation
-
A. Barascu, C. Le Chalony, G. Pennarun, D. Genet, N. Imam, B. Lopez and P. Bertrand: Oxidative stress induces an ATM-independent senescence pathway through p38 MAPKmediated lamin B1 accumulation. EMBO J, 31(5), 1080-94 (2012) DOI: 10.1038/emboj.2011.492
-
(2012)
EMBO J
, vol.31
, Issue.5
, pp. 1080-1094
-
-
Barascu, A.1
Le Chalony, C.2
Pennarun, G.3
Genet, D.4
Imam, N.5
Lopez, B.6
Bertrand, P.7
-
48
-
-
0035325264
-
Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts
-
Q. M. Chen, K. R. Prowse, V. C. Tu, S. Purdom and M. H. Linskens: Uncoupling the senescent phenotype from telomere shortening in hydrogen peroxide-treated fibroblasts. Exp Cell Res, 265(2), 294-303 (2001) DOI: 10.1006/excr.2001.5182
-
(2001)
Exp Cell Res
, vol.265
, Issue.2
, pp. 294-303
-
-
Chen, Q.M.1
Prowse, K.R.2
Tu, V.C.3
Purdom, S.4
Linskens, M.H.5
-
49
-
-
0042195820
-
Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts
-
S. Parrinello, E. Samper, A. Krtolica, J. Goldstein, S. Melov and J. Campisi: Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol, 5(8), 741-7 (2003) DOI: 10.1038/ncb1024
-
(2003)
Nat Cell Biol
, vol.5
, Issue.8
, pp. 741-747
-
-
Parrinello, S.1
Samper, E.2
Krtolica, A.3
Goldstein, J.4
Melov, S.5
Campisi, J.6
-
50
-
-
11244334166
-
Molecular signature of oncogenic rasinduced senescence
-
D. X. Mason, T. J. Jackson and A. W. Lin: Molecular signature of oncogenic rasinduced senescence. Oncogene, 23(57), 9238-46 (2004) DOI: 10.1038/sj.onc.1208172
-
(2004)
Oncogene
, vol.23
, Issue.57
, pp. 9238-9246
-
-
Mason, D.X.1
Jackson, T.J.2
Lin, A.W.3
-
51
-
-
0033539169
-
Microarray analysis of replicative senescence
-
D. N. Shelton, E. Chang, P. S. Whittier, D. Choi and W. D. Funk: Microarray analysis of replicative senescence. Curr Biol, 9(17), 939-45 (1999) DOI: 10.1016/S0960-9822(99)80420-5
-
(1999)
Curr Biol
, vol.9
, Issue.17
, pp. 939-945
-
-
Shelton, D.N.1
Chang, E.2
Whittier, P.S.3
Choi, D.4
Funk, W.D.5
-
52
-
-
77949881221
-
The senescence-associated secretory phenotype: The dark side of tumor suppression
-
J. P. Coppe, P. Y. Desprez, A. Krtolica and J. Campisi: The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol, 5, 99-118 (2010) DOI: 10.1146/annurev-pathol-121808-102144
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 99-118
-
-
Coppe, J.P.1
Desprez, P.Y.2
Krtolica, A.3
Campisi, J.4
-
53
-
-
44649101304
-
Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network
-
T. Kuilman, C. Michaloglou, L. C. Vredeveld, S. Douma, R. van Doorn, C. J. Desmet, L. A. Aarden, W. J. Mooi and D. S. Peeper: Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network. Cell, 133(6), 1019-31 (2008) DOI: 10.1016/j.cell.2008.03.039
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1019-1031
-
-
Kuilman, T.1
Michaloglou, C.2
Vredeveld, L.C.3
Douma, S.4
Van Doorn, R.5
Desmet, C.J.6
Aarden, L.A.7
Mooi, W.J.8
Peeper, D.S.9
-
54
-
-
44649120132
-
Chemokine signaling via the CXCR2 receptor reinforces senescence
-
J. C. Acosta, A. O'Loghlen, A. Banito, M. V. Guijarro, A. Augert, S. Raguz, M. Fumagalli, M. Da Costa, C. Brown, N. Popov, Y. Takatsu, J. Melamed, F. d'Adda di Fagagna, D. Bernard, E. Hernando and J. Gil: Chemokine signaling via the CXCR2 receptor reinforces senescence. Cell, 133(6), 1006-18 (2008) DOI: 10.1016/j.cell.2008.03.038
-
(2008)
Cell
, vol.133
, Issue.6
, pp. 1006-1018
-
-
Acosta, J.C.1
O'Loghlen, A.2
Banito, A.3
Guijarro, M.V.4
Augert, A.5
Raguz, S.6
Fumagalli, M.7
Da Costa, M.8
Brown, C.9
Popov, N.10
Takatsu, Y.11
Melamed, J.12
D'Adda Di-Fagagna, F.13
Bernard, D.14
Hernando, E.15
Gil, J.16
-
55
-
-
79955017452
-
P38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
-
A. Freund, C. K. Patil and J. Campisi: p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype. EMBO J, 30(8), 1536-48 (2011) DOI: 10.1038/emboj.2011.69
-
(2011)
EMBO J
, vol.30
, Issue.8
, pp. 1536-1548
-
-
Freund, A.1
Patil, C.K.2
Campisi, J.3
-
56
-
-
70350125106
-
Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
-
A. V. Orjalo, D. Bhaumik, B. K. Gengler, G. K. Scott and J. Campisi: Cell surface-bound IL-1alpha is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. Proc Natl Acad Sci U S A, 106(40), 17031-6 (2009) DOI: 10.1073/pnas.0905299106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.40
, pp. 17031-17036
-
-
Orjalo, A.V.1
Bhaumik, D.2
Gengler, B.K.3
Scott, G.K.4
Campisi, J.5
-
57
-
-
84938751873
-
MTOR regulates the pro-tumorigenic senescenceassociated secretory phenotype by promoting IL1A translation
-
R. M. Laberge, Y. Sun, A. V. Orjalo, C. K. Patil, A. Freund, L. Zhou, S. C. Curran, A. R. Davalos, K. A. Wilson-Edell, S. Liu, C. Limbad, M. Demaria, P. Li, G. B. Hubbard, Y. Ikeno, M. Javors, P. Y. Desprez, C. C. Benz, P. Kapahi, P. S. Nelson and J. Campisi: MTOR regulates the pro-tumorigenic senescenceassociated secretory phenotype by promoting IL1A translation. Nat Cell Biol, 17(8), 1049-61 (2015) DOI: 10.1038/ncb3195
-
(2015)
Nat Cell Biol
, vol.17
, Issue.8
, pp. 1049-1061
-
-
Laberge, R.M.1
Sun, Y.2
Orjalo, A.V.3
Patil, C.K.4
Freund, A.5
Zhou, L.6
Curran, S.C.7
Davalos, A.R.8
Wilson-Edell, K.A.9
Liu, S.10
Limbad, C.11
Demaria, M.12
Li, P.13
Hubbard, G.B.14
Ikeno, Y.15
Javors, M.16
Desprez, P.Y.17
Benz, C.C.18
Kapahi, P.19
Nelson, P.S.20
Campisi, J.21
more..
-
58
-
-
84940587703
-
MTOR regulates MAPKAPK2 translation to control the senescenceassociated secretory phenotype
-
N. Herranz, S. Gallage, M. Mellone, T. Wuestefeld, S. Klotz, C. J. Hanley, S. Raguz, J. C. Acosta, A. J. Innes, A. Banito, A. Georgilis, A. Montoya, K. Wolter, G. Dharmalingam, P. Faull, T. Carroll, J. P. Martinez-Barbera, P. Cutillas, F. Reisinger, M. Heikenwalder, R. A. Miller, D. Withers, L. Zender, G. J. Thomas and J. Gil: mTOR regulates MAPKAPK2 translation to control the senescenceassociated secretory phenotype. Nat Cell Biol, 17(9), 1205-17 (2015) DOI: 10.1038/ncb3225
-
(2015)
Nat Cell Biol
, vol.17
, Issue.9
, pp. 1205-1217
-
-
Herranz, N.1
Gallage, S.2
Mellone, M.3
Wuestefeld, T.4
Klotz, S.5
Hanley, C.J.6
Raguz, S.7
Acosta, J.C.8
Innes, A.J.9
Banito, A.10
Georgilis, A.11
Montoya, A.12
Wolter, K.13
Dharmalingam, G.14
Faull, P.15
Carroll, T.16
Martinez-Barbera, J.P.17
Cutillas, P.18
Reisinger, F.19
Heikenwalder, M.20
Miller, R.A.21
Withers, D.22
Zender, L.23
Thomas, G.J.24
Gil, J.25
more..
-
59
-
-
0033596121
-
Activators and target genes of rel/NF-kappaB transcription factors
-
H. L. Pahl: Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene, 18(49), 6853-66 (1999) DOI: 10.1038/sj.onc.1203239
-
(1999)
Oncogene
, vol.18
, Issue.49
, pp. 6853-6866
-
-
Pahl, H.L.1
-
60
-
-
84926523961
-
Senescenceassociated inflammatory responses: Aging and cancer perspectives
-
A. Lasry and Y. Ben-Neriah: Senescenceassociated inflammatory responses: aging and cancer perspectives. Trends Immunol, 36(4), 217-28 (2015) DOI: 10.1016/j.it.2015.02.009
-
(2015)
Trends Immunol
, vol.36
, Issue.4
, pp. 217-228
-
-
Lasry, A.1
Ben-Neriah, Y.2
-
61
-
-
0037180812
-
Points of control in inflammation
-
C. Nathan: Points of control in inflammation. Nature, 420(6917), 846-52 (2002) DOI: 10.1038/nature01320
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 846-852
-
-
Nathan, C.1
-
62
-
-
5444256371
-
Inflammation as a tumor promoter in cancer induction
-
M. Philip, D. A. Rowley and H. Schreiber: Inflammation as a tumor promoter in cancer induction. Semin Cancer Biol, 14(6), 433-9 (2004) DOI: 10.1016/j.semcancer.2004.06.006
-
(2004)
Semin Cancer Biol
, vol.14
, Issue.6
, pp. 433-439
-
-
Philip, M.1
Rowley, D.A.2
Schreiber, H.3
-
63
-
-
25844459154
-
NF-kappaB: Linking inflammation and immunity to cancer development and progression
-
M. Karin and F. R. Greten: NF-kappaB: linking inflammation and immunity to cancer development and progression. Nat Rev Immunol, 5(10), 749-59 (2005) DOI: 10.1038/nri1703
-
(2005)
Nat Rev Immunol
, vol.5
, Issue.10
, pp. 749-759
-
-
Karin, M.1
Greten, F.R.2
-
64
-
-
32944474237
-
Innate immunity gone awry: Linking microbial infections to chronic inflammation and cancer
-
M. Karin, T. Lawrence and V. Nizet: Innate immunity gone awry: linking microbial infections to chronic inflammation and cancer. Cell, 124(4), 823-35 (2006) DOI: 10.1016/j.cell.2006.02.016
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 823-835
-
-
Karin, M.1
Lawrence, T.2
Nizet, V.3
-
65
-
-
47949099098
-
Origin and physiological roles of inflammation
-
R. Medzhitov: Origin and physiological roles of inflammation. Nature, 454(7203), 428-435 (2008) DOI: 10.1038/nature07201
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 428-435
-
-
Medzhitov, R.1
-
66
-
-
39749084641
-
Active caspase-1 is a regulator of unconventional protein secretion
-
M. Keller, A. Rüegg, S. Werner and H.-D. Beer: Active Caspase-1 Is a Regulator of Unconventional Protein Secretion. Cell, 132(5), 818-831 (2008) DOI: 10.1016/j.cell.2007.12.040
-
(2008)
Cell
, vol.132
, Issue.5
, pp. 818-831
-
-
Keller, M.1
Rüegg, A.2
Werner, S.3
Beer, H.-D.4
-
67
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
O. Takeuchi and S. Akira: Pattern recognition receptors and inflammation. Cell, 140(6), 805-20 (2010) DOI: 10.1016/j.cell.2010.01.022
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
68
-
-
84883199752
-
Mitogen-activated protein kinases in innate immunity
-
J. S. Arthur and S. C. Ley: Mitogen-activated protein kinases in innate immunity. Nat Rev Immunol, 13(9), 679-92 (2013) DOI: 10.1038/nri3495
-
(2013)
Nat Rev Immunol
, vol.13
, Issue.9
, pp. 679-692
-
-
Arthur, J.S.1
Ley, S.C.2
-
69
-
-
34250823515
-
Gene-specific control of inflammation by TLRinduced chromatin modifications
-
S. L. Foster, D. C. Hargreaves and R. Medzhitov: Gene-specific control of inflammation by TLRinduced chromatin modifications. Nature, 447(7147), 972-8 (2007) DOI: 10.1038/nature05836
-
(2007)
Nature
, vol.447
, Issue.7147
, pp. 972-978
-
-
Foster, S.L.1
Hargreaves, D.C.2
Medzhitov, R.3
-
70
-
-
32044439558
-
Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response
-
V. R. Ramirez-Carrozzi, A. A. Nazarian, C. C. Li, S. L. Gore, R. Sridharan, A. N. Imbalzano and S. T. Smale: Selective and antagonistic functions of SWI/SNF and Mi-2beta nucleosome remodeling complexes during an inflammatory response. Genes Dev, 20(3), 282-96 (2006) DOI: 10.1101/gad.1383206
-
(2006)
Genes Dev
, vol.20
, Issue.3
, pp. 282-296
-
-
Ramirez-Carrozzi, V.R.1
Nazarian, A.A.2
Li, C.C.3
Gore, S.L.4
Sridharan, R.5
Imbalzano, A.N.6
Smale, S.T.7
-
71
-
-
2342464085
-
The two NF-kappaB activation pathways and their role in innate and adaptive immunity
-
G. Bonizzi and M. Karin: The two NF-kappaB activation pathways and their role in innate and adaptive immunity. Trends Immunol, 25(6), 280-8 (2004) DOI: 10.1016/j.it.2004.03.008
-
(2004)
Trends Immunol
, vol.25
, Issue.6
, pp. 280-288
-
-
Bonizzi, G.1
Karin, M.2
-
72
-
-
84858720357
-
Celebrating 25 years of NF-kappaB research
-
S. Ghosh and M. S. Hayden: Celebrating 25 years of NF-kappaB research. Immunol Rev, 246(1), 5-13 (2012) DOI: 10.1111/j.1600-065X.2012.01111.x
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 5-13
-
-
Ghosh, S.1
Hayden, M.S.2
-
73
-
-
84858711326
-
Role of NF-kappaB in epithelial biology
-
M. Pasparakis: Role of NF-kappaB in epithelial biology. Immunol Rev, 246(1), 346-58 (2012) DOI: 10.1111/j.1600-065X.2012.01109.x
-
(2012)
Immunol Rev
, vol.246
, Issue.1
, pp. 346-358
-
-
Pasparakis, M.1
-
74
-
-
33745298519
-
Nuclear factor-kappaB in cancer development and progression
-
M. Karin: Nuclear factor-kappaB in cancer development and progression. Nature, 441(7092), 431-6 (2006) DOI: 10.1038/nature04870
-
(2006)
Nature
, vol.441
, Issue.7092
, pp. 431-436
-
-
Karin, M.1
-
75
-
-
84925441813
-
Control of adaptive immunity by the innate immune system
-
A. Iwasaki and R. Medzhitov: Control of adaptive immunity by the innate immune system. Nat Immunol, 16(4), 343-53 (2015) DOI: 10.1038/ni.3123
-
(2015)
Nat Immunol
, vol.16
, Issue.4
, pp. 343-353
-
-
Iwasaki, A.1
Medzhitov, R.2
-
76
-
-
43449100667
-
Reactive oxygen species: Current knowledge and applications in cancer research and therapeutic
-
A. T. Lau, Y. Wang and J. F. Chiu: Reactive oxygen species: current knowledge and applications in cancer research and therapeutic. J Cell Biochem, 104(2), 657-67 (2008) DOI: 10.1002/jcb.21655
-
(2008)
J Cell Biochem
, vol.104
, Issue.2
, pp. 657-667
-
-
Lau, A.T.1
Wang, Y.2
Chiu, J.F.3
-
77
-
-
84875528275
-
The dendritic cell lineage: Ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting
-
M. Merad, P. Sathe, J. Helft, J. Miller and A. Mortha: The dendritic cell lineage: ontogeny and function of dendritic cells and their subsets in the steady state and the inflamed setting. Annu Rev Immunol, 31, 563-604 (2013) DOI: 10.1146/annurev-immunol -020711-074950
-
(2013)
Annu Rev Immunol
, vol.31
, pp. 563-604
-
-
Merad, M.1
Sathe, P.2
Helft, J.3
Miller, J.4
Mortha, A.5
-
78
-
-
84937516592
-
The resolution of inflammation: Principles and challenges
-
No DOI Found
-
S. E. Headland and L. V. Norling: The resolution of inflammation: Principles and challenges. Seminars in Immunology(0) (2015) No DOI Found
-
(2015)
Seminars in Immunology
-
-
Headland, S.E.1
Norling, L.V.2
-
79
-
-
58249118710
-
Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation
-
T. S. Gastardelo, A. S. Damazo, J. Dalli, R. J. Flower, M. Perretti and S. M. Oliani: Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation. The American Journal of Pathology, 174(1), 177-183 (2009) DOI: 10.2353/ajpath.2009.080342
-
(2009)
The American Journal of Pathology
, vol.174
, Issue.1
, pp. 177-183
-
-
Gastardelo, T.S.1
Damazo, A.S.2
Dalli, J.3
Flower, R.J.4
Perretti, M.5
Oliani, S.M.6
-
80
-
-
34250884498
-
Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: A novel mechanism for resolution of inflammation
-
D. El Kebir, L. Jozsef, T. Khreiss, W. Pan, N. A. Petasis, C. N. Serhan and J. G. Filep: Aspirin-triggered lipoxins override the apoptosis-delaying action of serum amyloid A in human neutrophils: a novel mechanism for resolution of inflammation. J Immunol, 179(1), 616-22 (2007) DOI: 10.4049/jimmunol.179.1.616
-
(2007)
J Immunol
, vol.179
, Issue.1
, pp. 616-622
-
-
El Kebir, D.1
Jozsef, L.2
Khreiss, T.3
Pan, W.4
Petasis, N.A.5
Serhan, C.N.6
Filep, J.G.7
-
81
-
-
78649338158
-
FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis
-
P. Maderna, D. C. Cottell, T. Toivonen, N. Dufton, J. Dalli, M. Perretti and C. Godson: FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis. FASEB J, 24(11), 4240-9 (2010) DOI: 10.1096/fj.10-159913
-
(2010)
FASEB J
, vol.24
, Issue.11
, pp. 4240-4249
-
-
Maderna, P.1
Cottell, D.C.2
Toivonen, T.3
Dufton, N.4
Dalli, J.5
Perretti, M.6
Godson, C.7
-
82
-
-
33947675961
-
Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages
-
M. Scannell, M. B. Flanagan, A. deStefani, K. J. Wynne, G. Cagney, C. Godson and P. Maderna: Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages. J Immunol, 178(7), 4595-605 (2007) DOI: 10.4049/jimmunol.178.7.4595
-
(2007)
J Immunol
, vol.178
, Issue.7
, pp. 4595-4605
-
-
Scannell, M.1
Flanagan, M.B.2
DeStefani, A.3
Wynne, K.J.4
Cagney, G.5
Godson, C.6
Maderna, P.7
-
83
-
-
76249100914
-
Cell surface externalization of annexin A1 as a failsafe mechanism preventing inflammatory responses during secondary necrosis
-
K. E. Blume, S. Soeroes, M. Waibel, H. Keppeler, S. Wesselborg, M. Herrmann, K. Schulze-Osthoff and K. Lauber: Cell surface externalization of annexin A1 as a failsafe mechanism preventing inflammatory responses during secondary necrosis. J Immunol, 183(12), 8138-47 (2009) DOI: 10.4049/jimmunol.0902250
-
(2009)
J Immunol
, vol.183
, Issue.12
, pp. 8138-8147
-
-
Blume, K.E.1
Soeroes, S.2
Waibel, M.3
Keppeler, H.4
Wesselborg, S.5
Herrmann, M.6
Schulze-Osthoff, K.7
Lauber, K.8
-
84
-
-
61449195530
-
Resolutionphase macrophages possess a unique inflammatory phenotype that is controlled by cAMP
-
J. Bystrom, I. Evans, J. Newson, M. Stables, I. Toor, N. van Rooijen, M. Crawford, P. Colville-Nash, S. Farrow and D. W. Gilroy: Resolutionphase macrophages possess a unique inflammatory phenotype that is controlled by cAMP. Blood, 112(10), 4117-27 (2008) DOI: 10.1182/blood-2007-12-129767
-
(2008)
Blood
, vol.112
, Issue.10
, pp. 4117-4127
-
-
Bystrom, J.1
Evans, I.2
Newson, J.3
Stables, M.4
Toor, I.5
Van Rooijen, N.6
Crawford, M.7
Colville-Nash, P.8
Farrow, S.9
Gilroy, D.W.10
-
85
-
-
0037265240
-
Alternative activation of macrophages
-
S. Gordon: Alternative activation of macrophages. Nat Rev Immunol, 3(1), 23-35 (2003) DOI: 10.1038/nri978
-
(2003)
Nat Rev Immunol
, vol.3
, Issue.1
, pp. 23-35
-
-
Gordon, S.1
-
86
-
-
78851471818
-
Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids
-
S. Schif-Zuck, N. Gross, S. Assi, R. Rostoker, C. N. Serhan and A. Ariel: Saturated-efferocytosis generates pro-resolving CD11blow macrophages: Modulation by resolvins and glucocorticoids. European Journal of Immunology, 41(2), 366-379 (2011) DOI: 10.1002/eji.201040801
-
(2011)
European Journal of Immunology
, vol.41
, Issue.2
, pp. 366-379
-
-
Schif-Zuck, S.1
Gross, N.2
Assi, S.3
Rostoker, R.4
Serhan, C.N.5
Ariel, A.6
-
87
-
-
0036143018
-
Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation
-
M.-L. N. Huynh, V. A. Fadok and P. M. Henson: Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation. The Journal of Clinical Investigation, 109(1), 41-50 (2002) DOI: 10.1172/JCI0211638
-
(2002)
The Journal of Clinical Investigation
, vol.109
, Issue.1
, pp. 41-50
-
-
Huynh, M.-L.N.1
Fadok, V.A.2
Henson, P.M.3
-
88
-
-
30044449982
-
Resolution of inflammation: The beginning programs the end
-
C. N. Serhan and J. Savill: Resolution of inflammation: the beginning programs the end. Nat Immunol, 6(12), 1191-7 (2005) DOI: 10.1038/ni1276
-
(2005)
Nat Immunol
, vol.6
, Issue.12
, pp. 1191-1197
-
-
Serhan, C.N.1
Savill, J.2
-
89
-
-
43249109607
-
Novel biphasic role for lymphocytes revealed during resolving inflammation
-
R. Rajakariar, T. Lawrence, J. Bystrom, M. Hilliard, P. Colville-Nash, G. Bellingan, D. Fitzgerald, M. M. Yaqoob and D. W. Gilroy: Novel biphasic role for lymphocytes revealed during resolving inflammation. Blood, 111(8), 4184-92 (2008) DOI: 10.1182/blood-2007-08-108936
-
(2008)
Blood
, vol.111
, Issue.8
, pp. 4184-4192
-
-
Rajakariar, R.1
Lawrence, T.2
Bystrom, J.3
Hilliard, M.4
Colville-Nash, P.5
Bellingan, G.6
Fitzgerald, D.7
Yaqoob, M.M.8
Gilroy, D.W.9
-
90
-
-
0038280022
-
Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signalregulated kinase-dependent TNF-alpha secretion from human T cells
-
A. Ariel, N. Chiang, M. Arita, N. A. Petasis and C. N. Serhan: Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signalregulated kinase-dependent TNF-alpha secretion from human T cells. J Immunol, 170(12), 6266-72 (2003) DOI: 10.4049/jimmunol.170.12.6266
-
(2003)
J Immunol
, vol.170
, Issue.12
, pp. 6266-6272
-
-
Ariel, A.1
Chiang, N.2
Arita, M.3
Petasis, N.A.4
Serhan, C.N.5
-
91
-
-
17844386319
-
IKK(alpha) limits macrophage NF-(kappa)B activation and contributes to the resolution of inflammation
-
T. Lawrence, M. Bebien, G. Y. Liu, V. Nizet and M. Karin: IKK(alpha) limits macrophage NF-(kappa)B activation and contributes to the resolution of inflammation. Nature, 434(7037), 1138-1143 (2005) DOI: 10.1038/nature03491
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1138-1143
-
-
Lawrence, T.1
Bebien, M.2
Liu, G.Y.3
Nizet, V.4
Karin, M.5
-
92
-
-
5444223519
-
The ubiquitin-modifying enzyme A20 is required for termination of tolllike receptor responses
-
D. L. Boone, E. E. Turer, E. G. Lee, R.-C. Ahmad, M. T. Wheeler, C. Tsui, P. Hurley, M. Chien, S. Chai, O. Hitotsumatsu, E. McNally, C. Pickart and A. Ma: The ubiquitin-modifying enzyme A20 is required for termination of Tolllike receptor responses. Nat Immunol, 5(10), 1052-1060 (2004) DOI: 10.1038/ni1110
-
(2004)
Nat Immunol
, vol.5
, Issue.10
, pp. 1052-1060
-
-
Boone, D.L.1
Turer, E.E.2
Lee, E.G.3
Ahmad, R.-C.4
Wheeler, M.T.5
Tsui, C.6
Hurley, P.7
Chien, M.8
Chai, S.9
Hitotsumatsu, O.10
McNally, E.11
Pickart, C.12
Ma, A.13
-
93
-
-
2542478996
-
The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response
-
W. S. Alexander and D. J. Hilton: The Role of Suppressors of Cytokine Signaling (SOCS) Proteins in Regulation of the Immune Response. Annual Review of Immunology, 22(1), 503-529 (2004) DOI: 10.1146/annurev. immunol.22.091003.090312
-
(2004)
Annual Review of Immunology
, vol.22
, Issue.1
, pp. 503-529
-
-
Alexander, W.S.1
Hilton, D.J.2
-
94
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
W. Xue, L. Zender, C. Miething, R. A. Dickins, E. Hernando, V. Krizhanovsky, C. Cordon-Cardo and S. W. Lowe: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature, 445(7128), 656-60 (2007) DOI: 10.1038/nature05529
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 656-660
-
-
Xue, W.1
Zender, L.2
Miething, C.3
Dickins, R.A.4
Hernando, E.5
Krizhanovsky, V.6
Cordon-Cardo, C.7
Lowe, S.W.8
-
95
-
-
81855169964
-
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
-
T. W. Kang, T. Yevsa, N. Woller, L. Hoenicke, T. Wuestefeld, D. Dauch, A. Hohmeyer, M. Gereke, R. Rudalska, A. Potapova, M. Iken, M. Vucur, S. Weiss, M. Heikenwalder, S. Khan, J. Gil, D. Bruder, M. Manns, P. Schirmacher, F. Tacke, M. Ott, T. Luedde, T. Longerich, S. Kubicka and L. Zender: Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature, 479(7374), 547-51 (2011) DOI: 10.1038/nature10599
-
(2011)
Nature
, vol.479
, Issue.7374
, pp. 547-551
-
-
Kang, T.W.1
Yevsa, T.2
Woller, N.3
Hoenicke, L.4
Wuestefeld, T.5
Dauch, D.6
Hohmeyer, A.7
Gereke, M.8
Rudalska, R.9
Potapova, A.10
Iken, M.11
Vucur, M.12
Weiss, S.13
Heikenwalder, M.14
Khan, S.15
Gil, J.16
Bruder, D.17
Manns, M.18
Schirmacher, P.19
Tacke, F.20
Ott, M.21
Luedde, T.22
Longerich, T.23
Kubicka, S.24
Zender, L.25
more..
-
96
-
-
80054789761
-
Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity
-
Y. Chien, C. Scuoppo, X. Wang, X. Fang, B. Balgley, J. E. Bolden, P. Premsrirut, W. Luo, A. Chicas, C. S. Lee, S. C. Kogan and S. W. Lowe: Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity. Genes Dev, 25(20), 2125-36 (2011) DOI: 10.1101/gad.17276711
-
(2011)
Genes Dev
, vol.25
, Issue.20
, pp. 2125-2136
-
-
Chien, Y.1
Scuoppo, C.2
Wang, X.3
Fang, X.4
Balgley, B.5
Bolden, J.E.6
Premsrirut, P.7
Luo, W.8
Chicas, A.9
Lee, C.S.10
Kogan, S.C.11
Lowe, S.W.12
-
97
-
-
77956875648
-
Stress-induced senescence in human and rodent astrocytes
-
A. Bitto, C. Sell, E. Crowe, A. Lorenzini, M. Malaguti, S. Hrelia and C. Torres: Stress-induced senescence in human and rodent astrocytes. Exp Cell Res, 316(17), 2961-8 (2010) DOI: 10.1016/j.yexcr.2010.06.021
-
(2010)
Exp Cell Res
, vol.316
, Issue.17
, pp. 2961-2968
-
-
Bitto, A.1
Sell, C.2
Crowe, E.3
Lorenzini, A.4
Malaguti, M.5
Hrelia, S.6
Torres, C.7
-
98
-
-
79959953782
-
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
-
A. Salminen, J. Ojala, K. Kaarniranta, A. Haapasalo, M. Hiltunen and H. Soininen: Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype. Eur J Neurosci, 34(1), 3-11 (2011) DOI: 10.1111/j.1460-9568.2011.07738.x
-
(2011)
Eur J Neurosci
, vol.34
, Issue.1
, pp. 3-11
-
-
Salminen, A.1
Ojala, J.2
Kaarniranta, K.3
Haapasalo, A.4
Hiltunen, M.5
Soininen, H.6
-
99
-
-
33748521288
-
Senescence in human intervertebral discs
-
S. Roberts, E. H. Evans, D. Kletsas, D. C. Jaffray and S. M. Eisenstein: Senescence in human intervertebral discs. Eur Spine J, 15 Suppl 3, S312-6 (2006) DOI: 10.1007/s00586-006-0126-8
-
(2006)
Eur Spine J
, vol.15
, pp. S312-S316
-
-
Roberts, S.1
Evans, E.H.2
Kletsas, D.3
Jaffray, D.C.4
Eisenstein, S.M.5
-
100
-
-
74549220692
-
Why is osteoarthritis an age-related disease?
-
A. Shane Anderson and R. F. Loeser: Why is osteoarthritis an age-related disease? Best Pract Res Clin Rheumatol, 24(1), 15-26 (2010) DOI: 10.1016/j.berh.2009.08.006
-
(2010)
Best Pract Res Clin Rheumatol
, vol.24
, Issue.1
, pp. 15-26
-
-
Shane Anderson, A.1
Loeser, R.F.2
-
101
-
-
39649122634
-
Evidence that senescent human prostate epithelial cells enhance tumorigenicity: Cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT
-
B. Bhatia, A. S. Multani, L. Patrawala, X. Chen, T. Calhoun-Davis, J. Zhou, L. Schroeder, R. Schneider-Broussard, J. Shen, S. Pathak, S. Chang and D. G. Tang: Evidence that senescent human prostate epithelial cells enhance tumorigenicity: cell fusion as a potential mechanism and inhibition by p16INK4a and hTERT. Int J Cancer, 122(7), 1483-95 (2008) DOI: 10.1002/ijc.23222
-
(2008)
Int J Cancer
, vol.122
, Issue.7
, pp. 1483-1495
-
-
Bhatia, B.1
Multani, A.S.2
Patrawala, L.3
Chen, X.4
Calhoun-Davis, T.5
Zhou, J.6
Schroeder, L.7
Schneider-Broussard, R.8
Shen, J.9
Pathak, S.10
Chang, S.11
Tang, D.G.12
-
102
-
-
0035834121
-
Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging
-
A. Krtolica, S. Parrinello, S. Lockett, P. Y. Desprez and J. Campisi: Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci U S A, 98(21), 12072-7 (2001) DOI: 10.1073/pnas.211053698
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, Issue.21
, pp. 12072-12077
-
-
Krtolica, A.1
Parrinello, S.2
Lockett, S.3
Desprez, P.Y.4
Campisi, J.5
-
103
-
-
34248197982
-
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
-
D. Liu and P. J. Hornsby: Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion. Cancer Res, 67(7), 3117-26 (2007) DOI: 10.1158/0008-5472.CAN-06-3452
-
(2007)
Cancer Res
, vol.67
, Issue.7
, pp. 3117-3126
-
-
Liu, D.1
Hornsby, P.J.2
-
104
-
-
84899736929
-
Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression
-
M. Rielland, D. J. Cantor, R. Graveline, C. Hajdu, L. Mara, D. Diaz Bde, G. Miller and G. David: Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression. J Clin Invest, 124(5), 2125-35 (2014) DOI: 10.1172/JCI72619
-
(2014)
J Clin Invest
, vol.124
, Issue.5
, pp. 2125-2135
-
-
Rielland, M.1
Cantor, D.J.2
Graveline, R.3
Hajdu, C.4
Mara, L.5
Diaz Bde, D.6
Miller, G.7
David, G.8
-
105
-
-
0042734423
-
The role of chondrocyte senescence in osteoarthritis
-
J. S. Price, J. G. Waters, C. Darrah, C. Pennington, D. R. Edwards, S. T. Donell and I. M. Clark: The role of chondrocyte senescence in osteoarthritis. Aging Cell, 1(1), 57-65 (2002) DOI: 10.1046/j.1474-9728.2002.00008.x
-
(2002)
Aging Cell
, vol.1
, Issue.1
, pp. 57-65
-
-
Price, J.S.1
Waters, J.G.2
Darrah, C.3
Pennington, C.4
Edwards, D.R.5
Donell, S.T.6
Clark, I.M.7
-
106
-
-
0035130153
-
Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: Evidence for senescent endothelial cells in vivo at sites of atherosclerosis
-
E. Vasile, Y. Tomita, L. F. Brown, O. Kocher and H. F. Dvorak: Differential expression of thymosin beta-10 by early passage and senescent vascular endothelium is modulated by VPF/VEGF: evidence for senescent endothelial cells in vivo at sites of atherosclerosis. FASEB J, 15(2), 458-66 (2001) DOI: 10.1096/fj.00-0051com
-
(2001)
FASEB J
, vol.15
, Issue.2
, pp. 458-466
-
-
Vasile, E.1
Tomita, Y.2
Brown, L.F.3
Kocher, O.4
Dvorak, H.F.5
-
107
-
-
33747625689
-
Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: Effects of telomerase and oxidative stress
-
C. Matthews, I. Gorenne, S. Scott, N. Figg, P. Kirkpatrick, A. Ritchie, M. Goddard and M. Bennett: Vascular smooth muscle cells undergo telomere-based senescence in human atherosclerosis: effects of telomerase and oxidative stress. Circ Res, 99(2), 156-64 (2006) DOI: 10.1161/01.RES.0000233315.38086.bc
-
(2006)
Circ Res
, vol.99
, Issue.2
, pp. 156-164
-
-
Matthews, C.1
Gorenne, I.2
Scott, S.3
Figg, N.4
Kirkpatrick, P.5
Ritchie, A.6
Goddard, M.7
Bennett, M.8
-
108
-
-
33846090789
-
Accumulation of senescent cells in mitotic tissue of aging primates
-
J. C. Jeyapalan, M. Ferreira, J. M. Sedivy and U. Herbig: Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev, 128(1), 36-44 (2007) DOI: 10.1016/j.mad.2006.11.008
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.1
, pp. 36-44
-
-
Jeyapalan, J.C.1
Ferreira, M.2
Sedivy, J.M.3
Herbig, U.4
-
109
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
P. J. Linton and K. Dorshkind: Age-related changes in lymphocyte development and function. Nat Immunol, 5(2), 133-9 (2004) DOI: 10.1038/ni1033
-
(2004)
Nat Immunol
, vol.5
, Issue.2
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
110
-
-
77955664688
-
Aging of the innate immune system
-
A. C. Shaw, S. Joshi, H. Greenwood, A. Panda and J. M. Lord: Aging of the innate immune system. Curr Opin Immunol, 22(4), 507-13 (2010) DOI: 10.1016/j.coi.2010.05.003
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.4
, pp. 507-513
-
-
Shaw, A.C.1
Joshi, S.2
Greenwood, H.3
Panda, A.4
Lord, J.M.5
-
111
-
-
13944270339
-
Senescent cells, tumor suppression, and organismal aging: Good citizens, bad neighbors
-
J. Campisi: Senescent cells, tumor suppression, and organismal aging: good citizens, bad neighbors. Cell, 120(4), 513-22 (2005) DOI: 10.1016/j.cell.2005.02.003
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 513-522
-
-
Campisi, J.1
-
112
-
-
31544479046
-
The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms
-
C. Bavik, I. Coleman, J. P. Dean, B. Knudsen, S. Plymate and P. S. Nelson: The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms. Cancer Res, 66(2), 794-802 (2006) DOI: 10.1158/0008-5472.CAN-05-1716
-
(2006)
Cancer Res
, vol.66
, Issue.2
, pp. 794-802
-
-
Bavik, C.1
Coleman, I.2
Dean, J.P.3
Knudsen, B.4
Plymate, S.5
Nelson, P.S.6
-
113
-
-
33749549246
-
Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence
-
J. P. Coppe, K. Kauser, J. Campisi and C. M. Beausejour: Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence. J Biol Chem, 281(40), 29568-74 (2006) DOI: 10.1074/jbc.M603307200
-
(2006)
J Biol Chem
, vol.281
, Issue.40
, pp. 29568-29574
-
-
Coppe, J.P.1
Kauser, K.2
Campisi, J.3
Beausejour, C.M.4
-
114
-
-
0141792500
-
Novel mechanisms of sublethal oxidant toxicity: Induction of premature senescence in human fibroblasts confers tumor promoter activity
-
T. K. Dilley, G. T. Bowden and Q. M. Chen: Novel mechanisms of sublethal oxidant toxicity: induction of premature senescence in human fibroblasts confers tumor promoter activity. Exp Cell Res, 290(1), 38-48 (2003) DOI: 10.1016/S0014-4827(03)00308-2
-
(2003)
Exp Cell Res
, vol.290
, Issue.1
, pp. 38-48
-
-
Dilley, T.K.1
Bowden, G.T.2
Chen, Q.M.3
-
115
-
-
34948822892
-
Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells
-
D. Yang, S. G. Elner, Z. M. Bian, G. O. Till, H. R. Petty and V. M. Elner: Pro-inflammatory cytokines increase reactive oxygen species through mitochondria and NADPH oxidase in cultured RPE cells. Exp Eye Res, 85(4), 462-72 (2007) DOI: 10.1016/j.exer.2007.06.013
-
(2007)
Exp Eye Res
, vol.85
, Issue.4
, pp. 462-472
-
-
Yang, D.1
Elner, S.G.2
Bian, Z.M.3
Till, G.O.4
Petty, H.R.5
Elner, V.M.6
-
116
-
-
84863635263
-
How do cytokines trigger genomic instability?
-
I. L. Aivaliotis, I. S. Pateras, M. Papaioannou, C. Glytsou, K. Kontzoglou, E. O. Johnson and V. Zoumpourlis: How do cytokines trigger genomic instability? J Biomed Biotechnol, 2012, 536761 (2012) DOI: 10.1155/2012/536761
-
(2012)
J Biomed Biotechnol
, vol.2012
, pp. 536761
-
-
Aivaliotis, I.L.1
Pateras, I.S.2
Papaioannou, M.3
Glytsou, C.4
Kontzoglou, K.5
Johnson, E.O.6
Zoumpourlis, V.7
-
117
-
-
80855128461
-
Cellular senescence: A link between cancer and age-related degenerative disease?
-
J. Campisi, J. K. Andersen, P. Kapahi and S. Melov: Cellular senescence: a link between cancer and age-related degenerative disease? Semin Cancer Biol, 21(6), 354-9 (2011) DOI: 10.1016/j.semcancer.2011.09.001
-
(2011)
Semin Cancer Biol
, vol.21
, Issue.6
, pp. 354-359
-
-
Campisi, J.1
Andersen, J.K.2
Kapahi, P.3
Melov, S.4
-
118
-
-
84975806501
-
Inflammatory networks in ageing, age-related diseases and longevity
-
S. Vasto, G. Candore, C. R. Balistreri, M. Caruso, G. Colonna-Romano, M. P. Grimaldi, F. Listi, D. Nuzzo, D. Lio and C. Caruso: Inflammatory networks in ageing, age-related diseases and longevity. Mech Ageing Dev, 128(1), 83-91 (2007) DOI: 10.1016/j.mad.2006.11.015
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.1
, pp. 83-91
-
-
Vasto, S.1
Candore, G.2
Balistreri, C.R.3
Caruso, M.4
Colonna-Romano, G.5
Grimaldi, M.P.6
Listi, F.7
Nuzzo, D.8
Lio, D.9
Caruso, C.10
-
119
-
-
4544368958
-
A flame burning within
-
L. Ferrucci, A. Ble, S. Bandinelli, F. Lauretani, K. Suthers and J. M. Guralnik: A flame burning within. Aging Clin Exp Res, 16(3), 240-3 (2004) DOI: 10.1007/BF03327390
-
(2004)
Aging Clin Exp Res
, vol.16
, Issue.3
, pp. 240-243
-
-
Ferrucci, L.1
Ble, A.2
Bandinelli, S.3
Lauretani, F.4
Suthers, K.5
Guralnik, J.M.6
-
120
-
-
84862794254
-
A senescent cell bystander effect: Senescence-induced senescence
-
G. Nelson, J. Wordsworth, C. Wang, D. Jurk, C. Lawless, C. Martin-Ruiz and T. von Zglinicki: A senescent cell bystander effect: senescence-induced senescence. Aging Cell, 11(2), 345-9 (2012) DOI: 10.1111/j.1474-9726.2012.00795.x
-
(2012)
Aging Cell
, vol.11
, Issue.2
, pp. 345-349
-
-
Nelson, G.1
Wordsworth, J.2
Wang, C.3
Jurk, D.4
Lawless, C.5
Martin-Ruiz, C.6
Von Zglinicki, T.7
-
121
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan and R. A. Weinberg: Hallmarks of cancer: the next generation. Cell, 144(5), 646-74 (2011) DOI: 10.1016/j.cell.2011.02.013
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
122
-
-
0023637114
-
The risk of colorectal cancer in ulcerative colitis. An epidemiologic study
-
O. Brostrom, R. Lofberg, B. Nordenvall, A. Ost and G. Hellers: The risk of colorectal cancer in ulcerative colitis. An epidemiologic study. Scand J Gastroenterol, 22(10), 1193-9 (1987) DOI: 10.3109/00365528708996463
-
(1987)
Scand J Gastroenterol
, vol.22
, Issue.10
, pp. 1193-1199
-
-
Brostrom, O.1
Lofberg, R.2
Nordenvall, B.3
Ost, A.4
Hellers, G.5
-
123
-
-
0021798650
-
Colorectal carcinoma in patients with Crohn's disease
-
No DOI Found
-
S. R. Hamilton: Colorectal carcinoma in patients with Crohn's disease. Gastroenterology, 89(2), 398-407 (1985) No DOI Found
-
(1985)
Gastroenterology
, vol.89
, Issue.2
, pp. 398-407
-
-
Hamilton, S.R.1
-
124
-
-
35148874235
-
Inflammation and cancer: A double-edged sword
-
T. Hagemann, F. Balkwill and T. Lawrence: Inflammation and cancer: a double-edged sword. Cancer Cell, 12(4), 300-1 (2007) DOI: 10.1016/j.ccr.2007.10.005
-
(2007)
Cancer Cell
, vol.12
, Issue.4
, pp. 300-301
-
-
Hagemann, T.1
Balkwill, F.2
Lawrence, T.3
-
125
-
-
84887559345
-
Anthracyclines induce DNA damage response-mediated protection against severe sepsis
-
N. Figueiredo, A. Chora, H. Raquel, N. Pejanovic, P. Pereira, B. Hartleben, A. Neves-Costa, C. Moita, D. Pedroso, A. Pinto, S. Marques, H. Faridi, P. Costa, R. Gozzelino, J. L. Zhao, M. P. Soares, M. Gama-Carvalho, J. Martinez, Q. Zhang, G. Doring, M. Grompe, J. P. Simas, T. B. Huber, D. Baltimore, V. Gupta, D. R. Green, J. A. Ferreira and L. F. Moita: Anthracyclines induce DNA damage response-mediated protection against severe sepsis. Immunity, 39(5), 874-84 (2013) DOI: 10.1016/j.immuni.2013.08.039
-
(2013)
Immunity
, vol.39
, Issue.5
, pp. 874-884
-
-
Figueiredo, N.1
Chora, A.2
Raquel, H.3
Pejanovic, N.4
Pereira, P.5
Hartleben, B.6
Neves-Costa, A.7
Moita, C.8
Pedroso, D.9
Pinto, A.10
Marques, S.11
Faridi, H.12
Costa, P.13
Gozzelino, R.14
Zhao, J.L.15
Soares, M.P.16
Gama-Carvalho, M.17
Martinez, J.18
Zhang, Q.19
Doring, G.20
Grompe, M.21
Simas, J.P.22
Huber, T.B.23
Baltimore, D.24
Gupta, V.25
Green, D.R.26
Ferreira, J.A.27
Moita, L.F.28
more..
-
126
-
-
84880338840
-
Reduced secretion of the inflammatory cytokine IL-1beta by stimulated peritoneal macrophages of radiosensitive balb/c mice after exposure to 0.5. or 0.7. Gy of ionizing radiation
-
B. Frischholz, R. Wunderlich, P. F. Ruhle, C. Schorn, F. Rodel, L. Keilholz, R. Fietkau, U. S. Gaipl and B. Frey: Reduced secretion of the inflammatory cytokine IL-1beta by stimulated peritoneal macrophages of radiosensitive Balb/c mice after exposure to 0.5. or 0.7. Gy of ionizing radiation. Autoimmunity (2013) DOI: 10.3109/08916934.2012.747522
-
(2013)
Autoimmunity
-
-
Frischholz, B.1
Wunderlich, R.2
Ruhle, P.F.3
Schorn, C.4
Rodel, F.5
Keilholz, L.6
Fietkau, R.7
Gaipl, U.S.8
Frey, B.9
-
127
-
-
84922071010
-
DEGRO guidelines for the radiotherapy of non-malignant disorders: Part II: Painful degenerative skeletal disorders
-
No DOI Found
-
O. J. Ott, M. Niewald, H. D. Weitmann, I. Jacob, I. A. Adamietz, U. Schaefer, L. Keilholz, R. Heyd, R. Muecke and D. German Cooperative Group on Radiotherapy for Benign: DEGRO guidelines for the radiotherapy of non-malignant disorders: Part II: Painful degenerative skeletal disorders. Strahlenther Onkol (2014) No DOI Found
-
(2014)
Strahlenther Onkol
-
-
Ott, O.J.1
Niewald, M.2
Weitmann, H.D.3
Jacob, I.4
Adamietz, I.A.5
Schaefer, U.6
Keilholz, L.7
Heyd, R.8
Muecke, R.9
German, D.10
-
128
-
-
0032748118
-
Radiotherapy of benign diseases: A pattern of care study in Germany
-
M. H. Seegenschmiedt, A. Katalinic, H. B. Makoski, W. Haase, G. Gademann and E. Hassenstein: (Radiotherapy of benign diseases: a pattern of care study in Germany). Strahlenther Onkol, 175(11), 541-7 (1999) DOI: 10.1007/s000660050038
-
(1999)
Strahlenther Onkol
, vol.175
, Issue.11
, pp. 541-547
-
-
Seegenschmiedt, M.H.1
Katalinic, A.2
Makoski, H.B.3
Haase, W.4
Gademann, G.5
Hassenstein, E.6
-
129
-
-
11144291517
-
Radiation therapy for nonmalignant diseases in Germany. Current concepts and future perspectives
-
M. H. Seegenschmiedt, O. Micke and N. Willich: Radiation therapy for nonmalignant diseases in Germany. Current concepts and future perspectives. Strahlenther Onkol, 180(11), 718-30 (2004) DOI: 10.1007/s00066-004-9197-9
-
(2004)
Strahlenther Onkol
, vol.180
, Issue.11
, pp. 718-730
-
-
Seegenschmiedt, M.H.1
Micke, O.2
Willich, N.3
-
130
-
-
84872859998
-
Benign painful shoulder syndrome: Initial results of a singlecenter prospective randomized radiotherapy dose-optimization trial
-
O. J. Ott, S. Hertel, U. S. Gaipl, B. Frey, M. Schmidt and R. Fietkau: Benign painful shoulder syndrome: initial results of a singlecenter prospective randomized radiotherapy dose-optimization trial. Strahlenther Onkol, 188(12), 1108-13 (2012) DOI: 10.1007/s00066-012-0237-6
-
(2012)
Strahlenther Onkol
, vol.188
, Issue.12
, pp. 1108-1113
-
-
Ott, O.J.1
Hertel, S.2
Gaipl, U.S.3
Frey, B.4
Schmidt, M.5
Fietkau, R.6
-
131
-
-
84896372212
-
The erlangen dose optimization trial for low-dose radiotherapy of benign painful elbow syndrome. Longterm results
-
O. J. Ott, S. Hertel, U. S. Gaipl, B. Frey, M. Schmidt and R. Fietkau: The Erlangen Dose Optimization trial for low-dose radiotherapy of benign painful elbow syndrome. Longterm results. Strahlenther Onkol, 190(3), 293-7 (2014) DOI: 10.1007/s00066-013-0504-1
-
(2014)
Strahlenther Onkol
, vol.190
, Issue.3
, pp. 293-297
-
-
Ott, O.J.1
Hertel, S.2
Gaipl, U.S.3
Frey, B.4
Schmidt, M.5
Fietkau, R.6
-
132
-
-
84877259331
-
Radiotherapy for calcaneodynia. Results of a single center prospective randomized dose optimization trial
-
O. J. Ott, C. Jeremias, U. S. Gaipl, B. Frey, M. Schmidt and R. Fietkau: Radiotherapy for calcaneodynia. Results of a single center prospective randomized dose optimization trial. Strahlenther Onkol, 189(4), 329-34 (2013) DOI: 10.1007/s00066-012-0256-3
-
(2013)
Strahlenther Onkol
, vol.189
, Issue.4
, pp. 329-334
-
-
Ott, O.J.1
Jeremias, C.2
Gaipl, U.S.3
Frey, B.4
Schmidt, M.5
Fietkau, R.6
-
133
-
-
84874081456
-
Radiotherapy for achillodynia: Results of a single-center prospective randomized dose-optimization trial
-
O. J. Ott, C. Jeremias, U. S. Gaipl, B. Frey, M. Schmidt and R. Fietkau: Radiotherapy for achillodynia: results of a single-center prospective randomized dose-optimization trial. Strahlenther Onkol, 189(2), 142-6 (2013) DOI: 10.1007/s00066-012-0240-y
-
(2013)
Strahlenther Onkol
, vol.189
, Issue.2
, pp. 142-146
-
-
Ott, O.J.1
Jeremias, C.2
Gaipl, U.S.3
Frey, B.4
Schmidt, M.5
Fietkau, R.6
-
134
-
-
38149070927
-
The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion
-
F. Rodel, D. Hofmann, J. Auer, L. Keilholz, M. Rollinghoff, R. Sauer and H. U. Beuscher: The anti-inflammatory effect of low-dose radiation therapy involves a diminished CCL20 chemokine expression and granulocyte/endothelial cell adhesion. Strahlenther Onkol, 184(1), 41-7 (2008) DOI: 10.1007/s00066-008-1776-8
-
(2008)
Strahlenther Onkol
, vol.184
, Issue.1
, pp. 41-47
-
-
Rodel, F.1
Hofmann, D.2
Auer, J.3
Keilholz, L.4
Rollinghoff, M.5
Sauer, R.6
Beuscher, H.U.7
-
135
-
-
0032773089
-
In vitro apoptosis in peripheral blood mononuclear cells induced by lowdose radiotherapy displays a discontinuous dose-dependence
-
P. Kern, L. Keilholz, C. Forster, M. H. Seegenschmiedt, R. Sauer and M. Herrmann: In vitro apoptosis in peripheral blood mononuclear cells induced by lowdose radiotherapy displays a discontinuous dose-dependence. Int J Radiat Biol, 75(8), 995-1003 (1999) DOI: 10.1080/095530099139755
-
(1999)
Int J Radiat Biol
, vol.75
, Issue.8
, pp. 995-1003
-
-
Kern, P.1
Keilholz, L.2
Forster, C.3
Seegenschmiedt, M.H.4
Sauer, R.5
Herrmann, M.6
-
136
-
-
84867017339
-
Low dose ionising radiation leads to a NF-kappaB dependent decreased secretion of active IL-1beta by activated macrophages with a discontinuous dose-dependency
-
B. Lodermann, R. Wunderlich, S. Frey, C. Schorn, S. Stangl, F. Rodel, L. Keilholz, R. Fietkau, U. S. Gaipl and B. Frey: Low dose ionising radiation leads to a NF-kappaB dependent decreased secretion of active IL-1beta by activated macrophages with a discontinuous dose-dependency. Int J Radiat Biol, 88(10), 727-34 (2012) DOI: 10.3109/09553002.2012.689464
-
(2012)
Int J Radiat Biol
, vol.88
, Issue.10
, pp. 727-734
-
-
Lodermann, B.1
Wunderlich, R.2
Frey, S.3
Schorn, C.4
Stangl, S.5
Rodel, F.6
Keilholz, L.7
Fietkau, R.8
Gaipl, U.S.9
Frey, B.10
-
137
-
-
84919382131
-
Low and moderate dose of ionising radiation up to 2 Gy modulates transmigration and chemotaxis of activated macrophages, provokes an anti-inflammatory cytokine milieu, but does not impact on viability and phagocytic function
-
No DOI Found
-
R. Wunderlich, A. Ernst, F. Rodel, R. Fietkau, O. Ott, K. Lauber, B. Frey and U. S. Gaipl: Low and moderate dose of ionising radiation up to 2 Gy modulates transmigration and chemotaxis of activated macrophages, provokes an anti-inflammatory cytokine milieu, but does not impact on viability and phagocytic function. Clin Exp Immunol (2014) No DOI Found
-
(2014)
Clin Exp Immunol
-
-
Wunderlich, R.1
Ernst, A.2
Rodel, F.3
Fietkau, R.4
Ott, O.5
Lauber, K.6
Frey, B.7
Gaipl, U.S.8
-
138
-
-
84895923545
-
Current concepts in clinical radiation oncology
-
M. Orth, K. Lauber, M. Niyazi, A. A. Friedl, M. Li, C. Maihofer, L. Schuttrumpf, A. Ernst, O. M. Niemoller and C. Belka: Current concepts in clinical radiation oncology. Radiat Environ Biophys, 53(1), 1-29 (2014) DOI: 10.1007/s00411-013-0497-2
-
(2014)
Radiat Environ Biophys
, vol.53
, Issue.1
, pp. 1-29
-
-
Orth, M.1
Lauber, K.2
Niyazi, M.3
Friedl, A.A.4
Li, M.5
Maihofer, C.6
Schuttrumpf, L.7
Ernst, A.8
Niemoller, O.M.9
Belka, C.10
-
139
-
-
84902076277
-
Kill and spread the word: Stimulation of antitumor immune responses in the context of radiotherapy
-
U. S. Gaipl, G. Multhoff, H. Scheithauer, K. Lauber, S. Hehlgans, B. Frey and F. Rodel: Kill and spread the word: stimulation of antitumor immune responses in the context of radiotherapy. Immunotherapy, 6(5), 597-610 (2014) DOI: 10.2217/imt.14.38
-
(2014)
Immunotherapy
, vol.6
, Issue.5
, pp. 597-610
-
-
Gaipl, U.S.1
Multhoff, G.2
Scheithauer, H.3
Lauber, K.4
Hehlgans, S.5
Frey, B.6
Rodel, F.7
-
140
-
-
84933050304
-
The tumour microenvironment after radiotherapy: Mechanisms of resistance and recurrence
-
H. E. Barker, J. T. Paget, A. A. Khan and K. J. Harrington: The tumour microenvironment after radiotherapy: mechanisms of resistance and recurrence. Nat Rev Cancer, 15(7), 409-25 (2015) DOI: 10.1038/nrc3958
-
(2015)
Nat Rev Cancer
, vol.15
, Issue.7
, pp. 409-425
-
-
Barker, H.E.1
Paget, J.T.2
Khan, A.A.3
Harrington, K.J.4
-
141
-
-
27844578432
-
P53-dependent accelerated senescence induced by ionizing radiation in breast tumour cells
-
K. R. Jones, L. W. Elmore, C. Jackson-Cook, G. Demasters, L. F. Povirk, S. E. Holt and D. A. Gewirtz: p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells. Int J Radiat Biol, 81(6), 445-58 (2005) DOI: 10.1080/09553000500168549
-
(2005)
Int J Radiat Biol
, vol.81
, Issue.6
, pp. 445-458
-
-
Jones, K.R.1
Elmore, L.W.2
Jackson-Cook, C.3
Demasters, G.4
Povirk, L.F.5
Holt, S.E.6
Gewirtz, D.A.7
-
142
-
-
16844373387
-
Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers
-
R. S. Roberson, S. J. Kussick, E. Vallieres, S. Y. Chen and D. Y. Wu: Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers. Cancer Res, 65(7), 2795-803 (2005) DOI: 10.1158/0008-5472.CAN-04-1270
-
(2005)
Cancer Res
, vol.65
, Issue.7
, pp. 2795-2803
-
-
Roberson, R.S.1
Kussick, S.J.2
Vallieres, E.3
Chen, S.Y.4
Wu, D.Y.5
-
144
-
-
0025894713
-
P53 mutations in human cancers
-
M. Hollstein, D. Sidransky, B. Vogelstein and C. C. Harris: p53 mutations in human cancers. Science, 253(5015), 49-53 (1991) DOI: 10.1126/science.1905840
-
(1991)
Science
, vol.253
, Issue.5015
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.C.4
-
145
-
-
70349902609
-
Low-dose radiation-induced senescent stromal fibroblasts render nearby breast cancer cells radioresistant
-
K. K. Tsai, J. Stuart, Y. Y. Chuang, J. B. Little and Z. M. Yuan: Low-dose radiation-induced senescent stromal fibroblasts render nearby breast cancer cells radioresistant. Radiat Res, 172(3), 306-13 (2009) DOI: 10.1667/RR1764.1
-
(2009)
Radiat Res
, vol.172
, Issue.3
, pp. 306-313
-
-
Tsai, K.K.1
Stuart, J.2
Chuang, Y.Y.3
Little, J.B.4
Yuan, Z.M.5
-
146
-
-
84872479990
-
Accelerated cellular senescence in solid tumor therapy
-
No DOI Found
-
P. C. Wu, Q. Wang, L. Grobman, E. Chu and D. Y. Wu: Accelerated cellular senescence in solid tumor therapy. Exp Oncol, 34(3), 298-305 (2012) No DOI Found
-
(2012)
Exp Oncol
, vol.34
, Issue.3
, pp. 298-305
-
-
Wu, P.C.1
Wang, Q.2
Grobman, L.3
Chu, E.4
Wu, D.Y.5
-
147
-
-
78650713936
-
Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: An exploratory analysis
-
R. Sidi, G. Pasello, I. Opitz, A. Soltermann, M. Tutic, H. Rehrauer, W. Weder, R. A. Stahel and E. Felley-Bosco: Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: an exploratory analysis. Eur J Cancer, 47(2), 326-32 (2011) DOI: 10.1016/j.ejca.2010.09.044
-
(2011)
Eur J Cancer
, vol.47
, Issue.2
, pp. 326-332
-
-
Sidi, R.1
Pasello, G.2
Opitz, I.3
Soltermann, A.4
Tutic, M.5
Rehrauer, H.6
Weder, W.7
Stahel, R.A.8
Felley-Bosco, E.9
-
148
-
-
0037011958
-
P53 mutant mice that display early ageing-associated phenotypes
-
S. D. Tyner, S. Venkatachalam, J. Choi, S. Jones, N. Ghebranious, H. Igelmann, X. Lu, G. Soron, B. Cooper, C. Brayton, S. H. Park, T. Thompson, G. Karsenty, A. Bradley and L. A. Donehower: p53 mutant mice that display early ageing-associated phenotypes. Nature, 415(6867), 45-53 (2002) DOI: 10.1038/415045a
-
(2002)
Nature
, vol.415
, Issue.6867
, pp. 45-53
-
-
Tyner, S.D.1
Venkatachalam, S.2
Choi, J.3
Jones, S.4
Ghebranious, N.5
Igelmann, H.6
Lu, X.7
Soron, G.8
Cooper, B.9
Brayton, C.10
Park, S.H.11
Thompson, T.12
Karsenty, G.13
Bradley, A.14
Donehower, L.A.15
-
149
-
-
77955516632
-
Cellular senescence predicts treatment outcome in metastasised colorectal cancer
-
A. M. Haugstetter, C. Loddenkemper, D. Lenze, J. Grone, C. Standfuss, I. Petersen, B. Dorken and C. A. Schmitt: Cellular senescence predicts treatment outcome in metastasised colorectal cancer. Br J Cancer, 103(4), 505-9 (2010) DOI: 10.1038/sj.bjc.6605784
-
(2010)
Br J Cancer
, vol.103
, Issue.4
, pp. 505-509
-
-
Haugstetter, A.M.1
Loddenkemper, C.2
Lenze, D.3
Grone, J.4
Standfuss, C.5
Petersen, I.6
Dorken, B.7
Schmitt, C.A.8
-
150
-
-
10744221485
-
In vivo activation of the p53 pathway by smallmolecule antagonists of MDM2
-
L. T. Vassilev, B. T. Vu, B. Graves, D. Carvajal, F. Podlaski, Z. Filipovic, N. Kong, U. Kammlott, C. Lukacs, C. Klein, N. Fotouhi and E. A. Liu: In vivo activation of the p53 pathway by smallmolecule antagonists of MDM2. Science, 303(5659), 844-8 (2004) DOI: 10.1126/science.1092472
-
(2004)
Science
, vol.303
, Issue.5659
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
151
-
-
33846899456
-
Restoration of p53 function leads to tumour regression in vivo
-
A. Ventura, D. G. Kirsch, M. E. McLaughlin, D. A. Tuveson, J. Grimm, L. Lintault, J. Newman, E. E. Reczek, R. Weissleder and T. Jacks: Restoration of p53 function leads to tumour regression in vivo. Nature, 445(7128), 661-5 (2007) DOI: 10.1038/nature05541
-
(2007)
Nature
, vol.445
, Issue.7128
, pp. 661-665
-
-
Ventura, A.1
Kirsch, D.G.2
McLaughlin, M.E.3
Tuveson, D.A.4
Grimm, J.5
Lintault, L.6
Newman, J.7
Reczek, E.E.8
Weissleder, R.9
Jacks, T.10
-
152
-
-
0036128899
-
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
-
V. J. Bykov, N. Issaeva, A. Shilov, M. Hultcrantz, E. Pugacheva, P. Chumakov, J. Bergman, K. G. Wiman and G. Selivanova: Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nat Med, 8(3), 282-8 (2002) DOI: 10.1038/nm0302-282
-
(2002)
Nat Med
, vol.8
, Issue.3
, pp. 282-288
-
-
Bykov, V.J.1
Issaeva, N.2
Shilov, A.3
Hultcrantz, M.4
Pugacheva, E.5
Chumakov, P.6
Bergman, J.7
Wiman, K.G.8
Selivanova, G.9
-
153
-
-
0043170883
-
Rescue of mutant p53 transcription function by ellipticine
-
Y. Peng, C. Li, L. Chen, S. Sebti and J. Chen: Rescue of mutant p53 transcription function by ellipticine. Oncogene, 22(29), 4478-87 (2003) DOI: 10.1038/sj.onc.1206777
-
(2003)
Oncogene
, vol.22
, Issue.29
, pp. 4478-4487
-
-
Peng, Y.1
Li, C.2
Chen, L.3
Sebti, S.4
Chen, J.5
-
154
-
-
84905976826
-
The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells
-
H. C. Chuang, L. P. Yang, A. L. Fitzgerald, A. Osman, S. H. Woo, J. N. Myers and H. D. Skinner: The p53-reactivating small molecule RITA induces senescence in head and neck cancer cells. PLoS One, 9(8), e104821 (2014) DOI: 10.1371/journal.pone.0104821
-
(2014)
PLoS One
, vol.9
, Issue.8
, pp. e104821
-
-
Chuang, H.C.1
Yang, L.P.2
Fitzgerald, A.L.3
Osman, A.4
Woo, S.H.5
Myers, J.N.6
Skinner, H.D.7
-
155
-
-
84896952141
-
Telomerase inhibitor imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells
-
K. M. Burchett, Y. Yan and M. M. Ouellette: Telomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cells. PLoS One, 9(1), e85155 (2014) DOI: 10.1371/journal.pone.0085155
-
(2014)
PLoS One
, vol.9
, Issue.1
, pp. e85155
-
-
Burchett, K.M.1
Yan, Y.2
Ouellette, M.M.3
-
156
-
-
33744799396
-
Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer
-
A. E. Hochreiter, H. Xiao, E. M. Goldblatt, S. M. Gryaznov, K. D. Miller, S. Badve, G. W. Sledge and B. S. Herbert: Telomerase template antagonist GRN163L disrupts telomere maintenance, tumor growth, and metastasis of breast cancer. Clin Cancer Res, 12(10), 3184-92 (2006) DOI: 10.1158/1078-0432.CCR-05-2760
-
(2006)
Clin Cancer Res
, vol.12
, Issue.10
, pp. 3184-3192
-
-
Hochreiter, A.E.1
Xiao, H.2
Goldblatt, E.M.3
Gryaznov, S.M.4
Miller, K.D.5
Badve, S.6
Sledge, G.W.7
Herbert, B.S.8
-
157
-
-
73349102719
-
MUC4 as a diagnostic marker in cancer
-
S. Chakraborty, M. Jain, A. R. Sasson and S. K. Batra: MUC4 as a diagnostic marker in cancer. Expert Opin Med Diagn, 2(8), 891-910 (2008) DOI: 10.1517/17530059.2.8.891
-
(2008)
Expert Opin Med Diagn
, vol.2
, Issue.8
, pp. 891-910
-
-
Chakraborty, S.1
Jain, M.2
Sasson, A.R.3
Batra, S.K.4
-
158
-
-
84898501515
-
MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway
-
M. A. Macha, S. Rachagani, P. Pai, S. Gupta, W. M. Lydiatt, R. B. Smith, S. L. Johansson, S. M. Lele, S. S. Kakar, J. H. Lee, J. Meza, A. K. Ganti, M. Jain and S. K. Batra: MUC4 regulates cellular senescence in head and neck squamous cell carcinoma through p16/Rb pathway. Oncogene, 34(13), 1698-708 (2015) DOI: 10.1038/onc.2014.102
-
(2015)
Oncogene
, vol.34
, Issue.13
, pp. 1698-1708
-
-
Macha, M.A.1
Rachagani, S.2
Pai, P.3
Gupta, S.4
Lydiatt, W.M.5
Smith, R.B.6
Johansson, S.L.7
Lele, S.M.8
Kakar, S.S.9
Lee, J.H.10
Meza, J.11
Ganti, A.K.12
Jain, M.13
Batra, S.K.14
-
159
-
-
84860518120
-
Radiation-inducible immunotherapy for cancer: Senescent tumor cells as a cancer vaccine
-
Y. Meng, E. V. Efimova, K. W. Hamzeh, T. E. Darga, H. J. Mauceri, Y. X. Fu, S. J. Kron and R. R. Weichselbaum: Radiation-inducible immunotherapy for cancer: senescent tumor cells as a cancer vaccine. Mol Ther, 20(5), 1046-55 (2012) DOI: 10.1038/mt.2012.19
-
(2012)
Mol Ther
, vol.20
, Issue.5
, pp. 1046-1055
-
-
Meng, Y.1
Efimova, E.V.2
Hamzeh, K.W.3
Darga, T.E.4
Mauceri, H.J.5
Fu, Y.X.6
Kron, S.J.7
Weichselbaum, R.R.8
-
160
-
-
84855172814
-
The pathogenesis of rheumatoid arthritis
-
I. B. McInnes and G. Schett: The pathogenesis of rheumatoid arthritis. N Engl J Med, 365(23), 2205-19 (2011) DOI: 10.1056/NEJMra1004965
-
(2011)
N Engl J Med
, vol.365
, Issue.23
, pp. 2205-2219
-
-
McInnes, I.B.1
Schett, G.2
-
161
-
-
0032587245
-
Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis
-
K. Taniguchi, H. Kohsaka, N. Inoue, Y. Terada, H. Ito, K. Hirokawa and N. Miyasaka: Induction of the p16INK4a senescence gene as a new therapeutic strategy for the treatment of rheumatoid arthritis. Nat Med, 5(7), 760-7 (1999) DOI: 10.1038/10480
-
(1999)
Nat Med
, vol.5
, Issue.7
, pp. 760-767
-
-
Taniguchi, K.1
Kohsaka, H.2
Inoue, N.3
Terada, Y.4
Ito, H.5
Hirokawa, K.6
Miyasaka, N.7
-
162
-
-
80054682555
-
Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype
-
J. P. Coppe, F. Rodier, C. K. Patil, A. Freund, P. Y. Desprez and J. Campisi: Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype. J Biol Chem, 286(42), 36396-403 (2011) DOI: 10.1074/jbc.M111.257071
-
(2011)
J Biol Chem
, vol.286
, Issue.42
, pp. 36396-36403
-
-
Coppe, J.P.1
Rodier, F.2
Patil, C.K.3
Freund, A.4
Desprez, P.Y.5
Campisi, J.6
-
163
-
-
0034676270
-
NF-kappaB activation in response to toxical and therapeutical agents: Role in inflammation and cancer treatment
-
V. Bours, G. Bonizzi, M. Bentires-Alj, F. Bureau, J. Piette, P. Lekeux and M. Merville: NF-kappaB activation in response to toxical and therapeutical agents: role in inflammation and cancer treatment. Toxicology, 153(1-3), 27-38 (2000) DOI: 10.1016/S0300-483X(00)00302-4
-
(2000)
Toxicology
, vol.153
, Issue.1-3
, pp. 27-38
-
-
Bours, V.1
Bonizzi, G.2
Bentires-Alj, M.3
Bureau, F.4
Piette, J.5
Lekeux, P.6
Merville, M.7
-
164
-
-
84864010194
-
Glucocorticoids suppress selected components of the senescence-associated secretory phenotype
-
R. M. Laberge, L. Zhou, M. R. Sarantos, F. Rodier, A. Freund, P. L. de Keizer, S. Liu, M. Demaria, Y. S. Cong, P. Kapahi, P. Y. Desprez, R. E. Hughes and J. Campisi: Glucocorticoids suppress selected components of the senescence-associated secretory phenotype. Aging Cell, 11(4), 569-78 (2012) DOI: 10.1111/j.1474-9726.2012.00818.x
-
(2012)
Aging Cell
, vol.11
, Issue.4
, pp. 569-578
-
-
Laberge, R.M.1
Zhou, L.2
Sarantos, M.R.3
Rodier, F.4
Freund, A.5
De Keizer, P.L.6
Liu, S.7
Demaria, M.8
Cong, Y.S.9
Kapahi, P.10
Desprez, P.Y.11
Hughes, R.E.12
Campisi, J.13
-
165
-
-
84855443905
-
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
-
H. D. Skinner, V. C. Sandulache, T. J. Ow, R. E. Meyn, J. S. Yordy, B. M. Beadle, A. L. Fitzgerald, U. Giri, K. K. Ang and J. N. Myers: TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence. Clin Cancer Res, 18(1), 290-300 (2012) DOI: 10.1158/1078-0432.CCR-11-2260
-
(2012)
Clin Cancer Res
, vol.18
, Issue.1
, pp. 290-300
-
-
Skinner, H.D.1
Sandulache, V.C.2
Ow, T.J.3
Meyn, R.E.4
Yordy, J.S.5
Beadle, B.M.6
Fitzgerald, A.L.7
Giri, U.8
Ang, K.K.9
Myers, J.N.10
-
166
-
-
84877822086
-
Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-kappaB activation
-
O. Moiseeva, X. Deschenes-Simard, E. St-Germain, S. Igelmann, G. Huot, A. E. Cadar, V. Bourdeau, M. N. Pollak and G. Ferbeyre: Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-kappaB activation. Aging Cell, 12(3), 489-98 (2013) DOI: 10.1111/acel.12075
-
(2013)
Aging Cell
, vol.12
, Issue.3
, pp. 489-498
-
-
Moiseeva, O.1
Deschenes-Simard, X.2
St-Germain, E.3
Igelmann, S.4
Huot, G.5
Cadar, A.E.6
Bourdeau, V.7
Pollak, M.N.8
Ferbeyre, G.9
-
167
-
-
77956415337
-
Metformin prevents tobacco carcinogen-induced lung tumorigenesis
-
R. M. Memmott, J. R. Mercado, C. R. Maier, S. Kawabata, S. D. Fox and P. A. Dennis: Metformin prevents tobacco carcinogen-induced lung tumorigenesis. Cancer Prev Res (Phila), 3(9), 1066-76 (2010) DOI: 10.1158/1940-6207.CAPR-10-0055
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, Issue.9
, pp. 1066-1076
-
-
Memmott, R.M.1
Mercado, J.R.2
Maier, C.R.3
Kawabata, S.4
Fox, S.D.5
Dennis, P.A.6
-
168
-
-
77956401999
-
Metformin and other biguanides in oncology: Advancing the research agenda
-
M. Pollak: Metformin and other biguanides in oncology: advancing the research agenda. Cancer Prev Res (Phila), 3(9), 1060-5 (2010) DOI: 10.1158/1940-6207.CAPR-10-0175
-
(2010)
Cancer Prev Res (Phila)
, vol.3
, Issue.9
, pp. 1060-1065
-
-
Pollak, M.1
-
169
-
-
84864072013
-
Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis
-
K. Bhalla, B. J. Hwang, R. E. Dewi, W. Twaddel, O. G. Goloubeva, K. K. Wong, N. K. Saxena, S. Biswal and G. D. Girnun: Metformin prevents liver tumorigenesis by inhibiting pathways driving hepatic lipogenesis. Cancer Prev Res (Phila), 5(4), 544-52 (2012) DOI: 10.1158/1940-6207.CAPR-11-0228
-
(2012)
Cancer Prev Res (Phila)
, vol.5
, Issue.4
, pp. 544-552
-
-
Bhalla, K.1
Hwang, B.J.2
Dewi, R.E.3
Twaddel, W.4
Goloubeva, O.G.5
Wong, K.K.6
Saxena, N.K.7
Biswal, S.8
Girnun, G.D.9
-
170
-
-
84866322945
-
Investigating metformin for cancer prevention and treatment: The end of the beginning
-
M. N. Pollak: Investigating metformin for cancer prevention and treatment: the end of the beginning. Cancer Discov, 2(9), 778-90 (2012) DOI: 10.1158/2159-8290.CD-12-0263
-
(2012)
Cancer Discov
, vol.2
, Issue.9
, pp. 778-790
-
-
Pollak, M.N.1
-
171
-
-
40949144895
-
Anti-inflammatory interventions of NF-kappaB signaling: Potential applications and risks
-
S. Uwe: Anti-inflammatory interventions of NF-kappaB signaling: potential applications and risks. Biochem Pharmacol, 75(8), 1567-79 (2008) DOI: 10.1016/j.bcp.2007.10.027
-
(2008)
Biochem Pharmacol
, vol.75
, Issue.8
, pp. 1567-1579
-
-
Uwe, S.1
-
172
-
-
0035139792
-
Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
-
Y. Yamamoto and R. B. Gaynor: Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest, 107(2), 135-42 (2001) DOI: 10.1172/JCI11914
-
(2001)
J Clin Invest
, vol.107
, Issue.2
, pp. 135-142
-
-
Yamamoto, Y.1
Gaynor, R.B.2
-
173
-
-
84885338213
-
NF-kappaB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-kappaB in immunemediated diseases
-
B. Sehnert, H. Burkhardt, J. T. Wessels, A. Schroder, M. J. May, D. Vestweber, J. Zwerina, K. Warnatz, F. Nimmerjahn, G. Schett, S. Dubel and R. E. Voll: NF-kappaB inhibitor targeted to activated endothelium demonstrates a critical role of endothelial NF-kappaB in immunemediated diseases. Proc Natl Acad Sci U S A, 110(41), 16556-61 (2013) DOI: 10.1073/pnas.1218219110
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, Issue.41
, pp. 16556-16561
-
-
Sehnert, B.1
Burkhardt, H.2
Wessels, J.T.3
Schroder, A.4
May, M.J.5
Vestweber, D.6
Zwerina, J.7
Warnatz, K.8
Nimmerjahn, F.9
Schett, G.10
Dubel, S.11
Voll, R.E.12
-
174
-
-
0025879694
-
Ionizing radiation induces expression and binding activity of the nuclear factor kappa B
-
M. A. Brach, R. Hass, M. L. Sherman, H. Gunji, R. Weichselbaum and D. Kufe: Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J Clin Invest, 88(2), 691-5 (1991) DOI: 10.1172/JCI115354
-
(1991)
J Clin Invest
, vol.88
, Issue.2
, pp. 691-695
-
-
Brach, M.A.1
Hass, R.2
Sherman, M.L.3
Gunji, H.4
Weichselbaum, R.5
Kufe, D.6
-
175
-
-
84864882225
-
Enhancement of radiosensitivity by a unique novel NF-kappaB inhibitor, DHMEQ, in prostate cancer
-
N. Kozakai, E. Kikuchi, M. Hasegawa, E. Suzuki, H. Ide, A. Miyajima, Y. Horiguchi, J. Nakashima, K. Umezawa, N. Shigematsu and M. Oya: Enhancement of radiosensitivity by a unique novel NF-kappaB inhibitor, DHMEQ, in prostate cancer. Br J Cancer, 107(4), 652-7 (2012) DOI: 10.1038/bjc.2012.321
-
(2012)
Br J Cancer
, vol.107
, Issue.4
, pp. 652-657
-
-
Kozakai, N.1
Kikuchi, E.2
Hasegawa, M.3
Suzuki, E.4
Ide, H.5
Miyajima, A.6
Horiguchi, Y.7
Nakashima, J.8
Umezawa, K.9
Shigematsu, N.10
Oya, M.11
-
176
-
-
12944273470
-
Targeting of nuclear factor kappaB pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: Antitumor and antiangiogenic potential in vivo
-
G. Matsumoto, J. Namekawa, M. Muta, T. Nakamura, H. Bando, K. Tohyama, M. Toi and K. Umezawa: Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin Cancer Res, 11(3), 1287-93 (2005)
-
(2005)
Clin Cancer Res
, vol.11
, Issue.3
, pp. 1287-1293
-
-
Matsumoto, G.1
Namekawa, J.2
Muta, M.3
Nakamura, T.4
Bando, H.5
Tohyama, K.6
Toi, M.7
Umezawa, K.8
-
177
-
-
13844310718
-
Screening of bioactive metabolites for pancreatic regeneration chemotherapy
-
H. Takatsuna and K. Umezawa: Screening of bioactive metabolites for pancreatic regeneration chemotherapy. Biomed Pharmacother, 58(10), 610-3 (2004) DOI: 10.1016/j.biopha.2004.10.003
-
(2004)
Biomed Pharmacother
, vol.58
, Issue.10
, pp. 610-613
-
-
Takatsuna, H.1
Umezawa, K.2
-
178
-
-
6044271614
-
Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin
-
D. V. Starenki, H. Namba, V. A. Saenko, A. Ohtsuru, S. Maeda, K. Umezawa and S. Yamashita: Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin. Clin Cancer Res, 10(20), 6821-9 (2004) DOI: 10.1158/1078-0432.CCR-04-0463
-
(2004)
Clin Cancer Res
, vol.10
, Issue.20
, pp. 6821-6829
-
-
Starenki, D.V.1
Namba, H.2
Saenko, V.A.3
Ohtsuru, A.4
Maeda, S.5
Umezawa, K.6
Yamashita, S.7
-
179
-
-
84863550186
-
NF-kappaB inhibition delays DNA damage-induced senescence and aging in mice
-
J. S. Tilstra, A. R. Robinson, J. Wang, S. Q. Gregg, C. L. Clauson, D. P. Reay, L. A. Nasto, C. M. St Croix, A. Usas, N. Vo, J. Huard, P. R. Clemens, D. B. Stolz, D. C. Guttridge, S. C. Watkins, G. A. Garinis, Y. Wang, L. J. Niedernhofer and P. D. Robbins: NF-kappaB inhibition delays DNA damage-induced senescence and aging in mice. J Clin Invest, 122(7), 2601-12 (2012) DOI: 10.1172/JCI45785
-
(2012)
J Clin Invest
, vol.122
, Issue.7
, pp. 2601-2612
-
-
Tilstra, J.S.1
Robinson, A.R.2
Wang, J.3
Gregg, S.Q.4
Clauson, C.L.5
Reay, D.P.6
Nasto, L.A.7
St Croix, C.M.8
Usas, A.9
Vo, N.10
Huard, J.11
Clemens, P.R.12
Stolz, D.B.13
Guttridge, D.C.14
Watkins, S.C.15
Garinis, G.A.16
Wang, Y.17
Niedernhofer, L.J.18
Robbins, P.D.19
-
180
-
-
84927740257
-
MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence
-
J. H. Cho, M. Dimri and G. P. Dimri: MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence. J Biol Chem, 290(16), 10555-67 (2015) DOI: 10.1074/jbc.M114.624361
-
(2015)
J Biol Chem
, vol.290
, Issue.16
, pp. 10555-10567
-
-
Cho, J.H.1
Dimri, M.2
Dimri, G.P.3
-
181
-
-
84886739871
-
A novel hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation
-
K. C. Chan, C. M. Ting, P. S. Chan, M. C. Lo, K. W. Lo, J. E. Curry, T. Smyth, A. W. Lee, W. T. Ng, G. S. Tsao, R. N. Wong, M. L. Lung and N. K. Mak: A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation. Mol Cancer, 12(1), 128 (2013) DOI: 10.1186/1476-4598-12-128
-
(2013)
Mol Cancer
, vol.12
, Issue.1
, pp. 128
-
-
Chan, K.C.1
Ting, C.M.2
Chan, P.S.3
Lo, M.C.4
Lo, K.W.5
Curry, J.E.6
Smyth, T.7
Lee, A.W.8
Ng, W.T.9
Tsao, G.S.10
Wong, R.N.11
Lung, M.L.12
Mak, N.K.13
-
182
-
-
84937642604
-
HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas
-
A. Ernst, H. Anders, H. Kapfhammer, M. Orth, R. Hennel, K. Seidl, N. Winssinger, C. Belka, S. Unkel and K. Lauber: HSP90 inhibition as a means of radiosensitizing resistant, aggressive soft tissue sarcomas. Cancer Lett, 365(2), 211-22 (2015) DOI: 10.1016/j.canlet.2015.05.024
-
(2015)
Cancer Lett
, vol.365
, Issue.2
, pp. 211-222
-
-
Ernst, A.1
Anders, H.2
Kapfhammer, H.3
Orth, M.4
Hennel, R.5
Seidl, K.6
Winssinger, N.7
Belka, C.8
Unkel, S.9
Lauber, K.10
|