-
1
-
-
0037025347
-
Inhibition of tumor necrosis factor-alpha-induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin
-
Ariga A, Namekawa J, Matsumoto N, Inoue J, Umezawa K (2002) Inhibition of tumor necrosis factor-alpha-induced nuclear translocation and activation of NF-kappa B by dehydroxymethylepoxyquinomicin. J Biol Chem 277: 24625-24630
-
(2002)
J Biol Chem
, vol.277
, pp. 24625-24630
-
-
Ariga, A.1
Namekawa, J.2
Matsumoto, N.3
Inoue, J.4
Umezawa, K.5
-
2
-
-
0025879694
-
Ionizing radiation induces expression and binding activity of the nuclear factor kappa B
-
Brach MA, Hass R, Sherman ML, Gunji H, Weichselbaum R, Kufe D (1991) Ionizing radiation induces expression and binding activity of the nuclear factor kappa B. J Clin Invest 88: 691-695
-
(1991)
J Clin Invest
, vol.88
, pp. 691-695
-
-
Brach, M.A.1
Hass, R.2
Sherman, M.L.3
Gunji, H.4
Weichselbaum, R.5
Kufe, D.6
-
3
-
-
0036174013
-
Activation of nuclear factor kappaB in radioresistance of TP53-inactive human keratinocytes
-
Chen X, Shen B, Xia L, Khaletzkiy A, Chu D, Wong JY, Li JJ (2002) Activation of nuclear factor kappaB in radioresistance of TP53-inactive human keratinocytes. Cancer Res 62: 1213-1221
-
(2002)
Cancer Res
, vol.62
, pp. 1213-1221
-
-
Chen, X.1
Shen, B.2
Xia, L.3
Khaletzkiy, A.4
Chu, D.5
Wong, J.Y.6
Li, J.J.7
-
4
-
-
1542426626
-
Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3
-
Chendil D, Ranga RS, Meigooni D, Sathishkumar S, Ahmed MM (2004) Curcumin confers radiosensitizing effect in prostate cancer cell line PC-3. Oncogene 23: 1599-1607
-
(2004)
Oncogene
, vol.23
, pp. 1599-1607
-
-
Chendil, D.1
Ranga, R.S.2
Meigooni, D.3
Sathishkumar, S.4
Ahmed, M.M.5
-
5
-
-
31344452370
-
Radiosensitization by targeting radioresistance-related genes with protein kinase A inhibitor in radioresistant cancer cells
-
Chin C, Bae JH, Kim MJ, Hwang JY, Kim SJ, Yoon MS, Lee MK, Kim DW, Chung BS, Kang CD, Kim SH (2005) Radiosensitization by targeting radioresistance- related genes with protein kinase A inhibitor in radioresistant cancer cells. Exp Mol Med 37: 608-618
-
(2005)
Exp Mol Med
, vol.37
, pp. 608-618
-
-
Chin, C.1
Bae, J.H.2
Kim, M.J.3
Hwang, J.Y.4
Kim, S.J.5
Yoon, M.S.6
Lee, M.K.7
Kim, D.W.8
Chung, B.S.9
Kang, C.D.10
Kim, S.H.11
-
6
-
-
0033509354
-
Genistein inhibits NF-kappa B activation in prostate cancer cells
-
Davis JN, Kucuk O, Sarkar FH (1999) Genistein inhibits NF-kappa B activation in prostate cancer cells. Nutr Cancer 35: 167-174
-
(1999)
Nutr Cancer
, vol.35
, pp. 167-174
-
-
Davis, J.N.1
Kucuk, O.2
Sarkar, F.H.3
-
7
-
-
0043128608
-
NB1011 induces Ser15 phosphorylation of p53 and activates the G2/M checkpoint
-
Dellinger RW, Karjian PL, Neuteboom ST (2003) NB1011 induces Ser15 phosphorylation of p53 and activates the G2/M checkpoint. Anticancer Drugs 14: 449-455
-
(2003)
Anticancer Drugs
, vol.14
, pp. 449-455
-
-
Dellinger, R.W.1
Karjian, P.L.2
Neuteboom, S.T.3
-
8
-
-
0345121122
-
Adenovirus-mediated inhibition of NF-kappaB confers chemo-sensitization and apoptosis in prostate cancer cells
-
Flynn Jr. V, Ramanitharan A, Moparty K, Davis R, Sikka S, Agrawal KC, Abdel-Mageed AB (2003) Adenovirus-mediated inhibition of NF-kappaB confers chemo-sensitization and apoptosis in prostate cancer cells. Int J Oncol 23: 317-323
-
(2003)
Int J Oncol
, vol.23
, pp. 317-323
-
-
Flynn Jr., V.1
Ramanitharan, A.2
Moparty, K.3
Davis, R.4
Sikka, S.5
Agrawal, K.C.6
Abdel-Mageed, A.B.7
-
9
-
-
33645520585
-
Sensitizing hormone-refractory prostate cancer cells to drug treatment by targeting 14-3-3sigma
-
Han B, Xie H, Chen Q, Zhang JT (2006) Sensitizing hormone-refractory prostate cancer cells to drug treatment by targeting 14-3-3sigma. Mol Cancer Ther 5: 903-912
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 903-912
-
-
Han, B.1
Xie, H.2
Chen, Q.3
Zhang, J.T.4
-
11
-
-
0037227989
-
Suppression of hormone-refractory prostate cancer by a novel nuclear factor kappaB inhibitor in nude mice
-
Kikuchi E, Horiguchi Y, Nakashima J, Kuroda K, Oya M, Ohigashi T, Takahashi N, Shima Y, Umezawa K, Murai M (2003) Suppression of hormone-refractory prostate cancer by a novel nuclear factor kappaB inhibitor in nude mice. Cancer Res 63: 107-110
-
(2003)
Cancer Res
, vol.63
, pp. 107-110
-
-
Kikuchi, E.1
Horiguchi, Y.2
Nakashima, J.3
Kuroda, K.4
Oya, M.5
Ohigashi, T.6
Takahashi, N.7
Shima, Y.8
Umezawa, K.9
Murai, M.10
-
12
-
-
0346363495
-
Radical prostatectomy, external beam radiotherapy o72 Gy, external beam radiotherapy 4or 72 Gy, permanent seed implantation, or combined seeds/external beam radiotherapy for stage T1-T2 prostate cancer
-
Kupelian PA, Potters L, Khuntia D, Ciezki JP, Reddy CA, Reuther AM, Carlson TP, Klein EA (2004) Radical prostatectomy, external beam radiotherapy o72 Gy, external beam radiotherapy 4or 72 Gy, permanent seed implantation, or combined seeds/external beam radiotherapy for stage T1-T2 prostate cancer. Int J Radiat Oncol Biol Phys 58: 25-33
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 25-33
-
-
Kupelian, P.A.1
Potters, L.2
Khuntia, D.3
Ciezki, J.P.4
Reddy, C.A.5
Reuther, A.M.6
Carlson, T.P.7
Klein, E.A.8
-
13
-
-
23044483988
-
Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer
-
Kuroda K, Horiguchi Y, Nakashima J, Kikuchi E, Kanao K, Miyajima A, Ohigashi T, Umezawa K, Murai M (2005) Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer. Clin Cancer Res 11: 5590-5594
-
(2005)
Clin Cancer Res
, vol.11
, pp. 5590-5594
-
-
Kuroda, K.1
Horiguchi, Y.2
Nakashima, J.3
Kikuchi, E.4
Kanao, K.5
Miyajima, A.6
Ohigashi, T.7
Umezawa, K.8
Murai, M.9
-
14
-
-
12944273470
-
Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: Antitumor and antiangiogenic potential in vivo
-
Matsumoto G, Namekawa J, Muta M, Nakamura T, Bando H, Tohyama K, Toi M, Umezawa K (2005) Targeting of nuclear factor kappaB Pathways by dehydroxymethylepoxyquinomicin, a novel inhibitor of breast carcinomas: antitumor and antiangiogenic potential in vivo. Clin Cancer Res 11: 1287-1293
-
(2005)
Clin Cancer Res
, vol.11
, pp. 1287-1293
-
-
Matsumoto, G.1
Namekawa, J.2
Muta, M.3
Nakamura, T.4
Bando, H.5
Tohyama, K.6
Toi, M.7
Umezawa, K.8
-
15
-
-
0034178264
-
Synthesis of NF-kappaB activation inhibitors derived from epoxyquinomicin C
-
Matsumoto N, Ariga A, To-e S, Nakamura H, Agata N, Hirano S, Inoue J, Umezawa K (2000) Synthesis of NF-kappaB activation inhibitors derived from epoxyquinomicin C. Bioorg Med Chem Lett 10: 865-869
-
(2000)
Bioorg Med Chem Lett
, vol.10
, pp. 865-869
-
-
Matsumoto, N.1
Ariga, A.2
To-E, S.3
Nakamura, H.4
Agata, N.5
Hirano, S.6
Inoue, J.7
Umezawa, K.8
-
16
-
-
24944487318
-
In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia
-
Ohsugi T, Horie R, Kumasaka T, Ishida A, Ishida T, Yamaguchi K, Watanabe T, Umezawa K, Urano T (2005) In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia. Carcinogenesis 26: 1382-1388
-
(2005)
Carcinogenesis
, vol.26
, pp. 1382-1388
-
-
Ohsugi, T.1
Horie, R.2
Kumasaka, T.3
Ishida, A.4
Ishida, T.5
Yamaguchi, K.6
Watanabe, T.7
Umezawa, K.8
Urano, T.9
-
17
-
-
0033578993
-
Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells
-
Pajonk F, Pajonk K, McBride WH (1999) Inhibition of NF-kappaB, clonogenicity, and radiosensitivity of human cancer cells. J Natl Cancer Inst 91: 1956-1960
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1956-1960
-
-
Pajonk, F.1
Pajonk, K.2
McBride, W.H.3
-
18
-
-
0033517999
-
Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen
-
Palayoor ST, Youmell MY, Calderwood SK, Coleman CN, Price BD (1999) Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen. Oncogene 18: 7389-7394
-
(1999)
Oncogene
, vol.18
, pp. 7389-7394
-
-
Palayoor, S.T.1
Youmell, M.Y.2
Calderwood, S.K.3
Coleman, C.N.4
Price, B.D.5
-
19
-
-
0036680314
-
Prostate cancer radiation dose response: Results of the M. D. Anderson phase III randomized trial
-
Pollack A, Zagars GK, Starkschall G, Antolak JA, Lee JJ, Huang E, von Eschenbach AC, Kuban DA, Rosen I (2002) Prostate cancer radiation dose response: results of the M. D. Anderson phase III randomized trial. Int J Radiat Oncol Biol Phys 53: 1097-1105
-
(2002)
Int J Radiat Oncol Biol Phys
, vol.53
, pp. 1097-1105
-
-
Pollack, A.1
Zagars, G.K.2
Starkschall, G.3
Antolak, J.A.4
Lee, J.J.5
Huang, E.6
Von Eschenbach, A.C.7
Kuban, D.A.8
Rosen, I.9
-
20
-
-
33646727546
-
Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
-
Raffoul JJ, Wang Y, Kucuk O, Forman JD, Sarkar FH, Hillman GG (2006) Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest. BMC Cancer 6: 107
-
(2006)
BMC Cancer
, vol.6
, pp. 107
-
-
Raffoul, J.J.1
Wang, Y.2
Kucuk, O.3
Forman, J.D.4
Sarkar, F.H.5
Hillman, G.G.6
-
21
-
-
6044271614
-
Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin
-
Starenki DV, Namba H, Saenko VA, Ohtsuru A, Maeda S, Umezawa K, Yamashita S (2004) Induction of thyroid cancer cell apoptosis by a novel nuclear factor kappaB inhibitor, dehydroxymethylepoxyquinomicin. Clin Cancer Res 10: 6821-6829
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6821-6829
-
-
Starenki, D.V.1
Namba, H.2
Saenko, V.A.3
Ohtsuru, A.4
Maeda, S.5
Umezawa, K.6
Yamashita, S.7
-
22
-
-
34748904141
-
The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN
-
Sun St Y, Clair DK, Fang F, Warren GW, Rangnekar VM, Crooks St PA, Clair WH (2007) The radiosensitization effect of parthenolide in prostate cancer cells is mediated by nuclear factor-kappaB inhibition and enhanced by the presence of PTEN. Mol Cancer Ther 6: 2477-2486
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 2477-2486
-
-
Sun St, Y.1
Clair, D.K.2
Fang, F.3
Warren, G.W.4
Rangnekar, V.M.5
Crooks St, P.A.6
Clair, W.H.7
-
23
-
-
15144347816
-
Defective control of apoptosis, radiosensitivity, and spindle checkpoint in ataxia telangiectasia
-
Takagi M, Delia D, Chessa L, Iwata S, Shigeta T, Kanke Y, Goi K, Asada M, Eguchi M, Kodama C, Mizutani S (1998) Defective control of apoptosis, radiosensitivity, and spindle checkpoint in ataxia telangiectasia. Cancer Res 58: 4923-4929
-
(1998)
Cancer Res
, vol.58
, pp. 4923-4929
-
-
Takagi, M.1
Delia, D.2
Chessa, L.3
Iwata, S.4
Shigeta, T.5
Kanke, Y.6
Goi, K.7
Asada, M.8
Eguchi, M.9
Kodama, C.10
Mizutani, S.11
-
24
-
-
13844310718
-
Screening of bioactive metabolites for pancreatic regeneration chemotherapy
-
Takatsuna H, Umezawa K (2004) Screening of bioactive metabolites for pancreatic regeneration chemotherapy. Biomed Pharmacother 58: 610-613
-
(2004)
Biomed Pharmacother
, vol.58
, pp. 610-613
-
-
Takatsuna, H.1
Umezawa, K.2
-
25
-
-
0035891320
-
Inhibition of JNK activation through NF-kappaB target genes
-
Tang G, Minemoto Y, Dibling B, Purcell NH, Li Z, Karin M, Lin A (2001) Inhibition of JNK activation through NF-kappaB target genes. Nature 414: 313-317
-
(2001)
Nature
, vol.414
, pp. 313-317
-
-
Tang, G.1
Minemoto, Y.2
Dibling, B.3
Purcell, N.H.4
Li, Z.5
Karin, M.6
Lin, A.7
-
26
-
-
0035810054
-
Regulation of the G2/M transition by p53
-
Taylor WR, Stark GR (2001) Regulation of the G2/M transition by p53. Oncogene 20: 1803-1815
-
(2001)
Oncogene
, vol.20
, pp. 1803-1815
-
-
Taylor, W.R.1
Stark, G.R.2
-
27
-
-
0037075898
-
Activation of the p53 tumor suppressor protein
-
Vousden KH (2002) Activation of the p53 tumor suppressor protein. Biochim Biophys Acta 1602: 47-59
-
(2002)
Biochim Biophys Acta
, vol.1602
, pp. 47-59
-
-
Vousden, K.H.1
-
28
-
-
13244252299
-
A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo
-
Watanabe M, Dewan MZ, Okamura T, Sasaki M, Itoh K, Higashihara M, Mizoguchi H, Honda M, Sata T, Watanabe T, Yamamoto N, Umezawa K, Horie R (2005) A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo. Int J Cancer 114: 32-38
-
(2005)
Int J Cancer
, vol.114
, pp. 32-38
-
-
Watanabe, M.1
Dewan, M.Z.2
Okamura, T.3
Sasaki, M.4
Itoh, K.5
Higashihara, M.6
Mizoguchi, H.7
Honda, M.8
Sata, T.9
Watanabe, T.10
Yamamoto, N.11
Umezawa, K.12
Horie, R.13
-
29
-
-
0141954159
-
Cyclooxygenase-2 inhibitor NS398 enhances antitumor effect of irradiation on hormone refractory human prostate carcinoma cells
-
Wen B, Deutsch E, Eschwege P, De Crevoisier R, Nasr E, Eschwege F, Bourhis J (2003) Cyclooxygenase-2 inhibitor NS398 enhances antitumor effect of irradiation on hormone refractory human prostate carcinoma cells. J Urol 170: 2036-2039
-
(2003)
J Urol
, vol.170
, pp. 2036-2039
-
-
Wen, B.1
Deutsch, E.2
Eschwege, P.3
De Crevoisier, R.4
Nasr, E.5
Eschwege, F.6
Bourhis, J.7
-
30
-
-
52449131840
-
Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues
-
Yamamoto M, Horie R, Takeiri M, Kozawa I, Umezawa K (2008) Inactivation of NF-kappaB components by covalent binding of (-)- dehydroxymethylepoxyquinomicin to specific cysteine residues. J Med Chem 51: 5780-5788
-
(2008)
J Med Chem
, vol.51
, pp. 5780-5788
-
-
Yamamoto, M.1
Horie, R.2
Takeiri, M.3
Kozawa, I.4
Umezawa, K.5
-
31
-
-
0034891284
-
High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancer
-
Zelefsky MJ, Fuks Z, Hunt M, Lee HJ, Lombardi D, Ling CC, Reuter VE, Venkatraman ES, Leibel SA (2001) High dose radiation delivered by intensity modulated conformal radiotherapy improves the outcome of localized prostate cancer. J Urol 166: 876-881
-
(2001)
J Urol
, vol.166
, pp. 876-881
-
-
Zelefsky, M.J.1
Fuks, Z.2
Hunt, M.3
Lee, H.J.4
Lombardi, D.5
Ling, C.C.6
Reuter, V.E.7
Venkatraman, E.S.8
Leibel, S.A.9
|