Low dose ionising radiation leads to a NF-κB dependent decreased secretion of active IL-1β by activated macrophages with a discontinuous dose-dependency

International Journal of Radiation Biology

Volumn 88, Issue 10, 2012, Pages 727-734

  Lödermann, Barbara ^a   Wunderlich, Roland ^a   Frey, Silke ^a   Schorn, Christine ^a   Stangl, Sonja ^a   Rödel, Franz ^b   Keilholz, Ludwig ^c   Fietkau, Rainer ^a   Gaipl, Udo S ^a   Frey, Benjamin ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c Clinical Center Bayreuth   (Germany)

Author keywords

Activated macrophages; Discontinuous dose dependency; IL 1 ; Inflammation; Low dose radiation therapy; NF B; P65

Indexed keywords

CELL PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1BETA; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; TRANSCRIPTION FACTOR REL; TRANSCRIPTION FACTOR RELA; URATE;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IONIZING RADIATION; LOW ENERGY RADIATION; MACROPHAGE ACTIVATION; PRIORITY JOURNAL; RADIATION DOSE; WESTERN BLOTTING;

CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; INFLAMMATION; INTERLEUKIN-1BETA; MACROPHAGES; TRANSCRIPTION FACTOR RELA; X-RAYS;

EID: 84867017339     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2012.689464     Document Type: Article

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