-
1
-
-
84875446642
-
BAP1 and cancer
-
Carbone M., et al. BAP1 and cancer. Nat. Rev. Cancer 13, 153-159 (2013
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 153-159
-
-
Carbone, M.1
-
2
-
-
78649700287
-
Frequent mutation of BAP1 in metastasizing uveal melanomas
-
Harbour J. W., et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science 330, 1410-1413 (2010
-
(2010)
Science
, vol.330
, pp. 1410-1413
-
-
Harbour, J.W.1
-
3
-
-
79959694149
-
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma
-
Bott M., et al. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nat. Genet. 43, 668-672 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 668-672
-
-
Bott, M.1
-
4
-
-
80053385701
-
Germline BAP1 mutations predispose to malignant mesothelioma
-
Testa J. R., et al. Germline BAP1 mutations predispose to malignant mesothelioma. Nat. Genet. 43, 1022-1025 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 1022-1025
-
-
Testa, J.R.1
-
5
-
-
80053386896
-
Germline mutations in BAP1 predispose to melanocytic tumors
-
Wiesner T., et al. Germline mutations in BAP1 predispose to melanocytic tumors. Nat. Genet. 43, 1018-1021 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 1018-1021
-
-
Wiesner, T.1
-
6
-
-
80053434128
-
Germline BAP1 mutations and tumor susceptibility
-
Goldstein A. M. Germline BAP1 mutations and tumor susceptibility. Nat. Genet. 43, 925-926 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 925-926
-
-
Goldstein, A.M.1
-
7
-
-
84862988411
-
BAP1 loss defines a new class of renal cell carcinoma
-
Peña-Llopis S., et al. BAP1 loss defines a new class of renal cell carcinoma. Nat. Genet. 44, 751-759 (2012
-
(2012)
Nat. Genet
, vol.44
, pp. 751-759
-
-
Peña-Llopis, S.1
-
8
-
-
84866467141
-
Loss of the tumor suppressor BAP1 causes myeloid transformation
-
Dey A., et al. Loss of the tumor suppressor BAP1 causes myeloid transformation. Science 337, 1541-1546 (2012
-
(2012)
Science
, vol.337
, pp. 1541-1546
-
-
Dey, A.1
-
9
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C., et al. Mutational landscape and significance across 12 major cancer types. Nature 502, 333-339 (2013
-
(2013)
Nature
, vol.502
, pp. 333-339
-
-
Kandoth, C.1
-
10
-
-
84891912266
-
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
-
Yu H., et al. Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair. Proc. Natl Acad. Sci. USA 111, 285-290 (2014
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 285-290
-
-
Yu, H.1
-
11
-
-
84923364710
-
Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis
-
Lee H.-S., Lee S.-A., Hur S.-K., Seo J.-W., & Kwon J. Stabilization and targeting of INO80 to replication forks by BAP1 during normal DNA synthesis. Nat. Commun. 5, 5128 (2014
-
(2014)
Nat. Commun
, vol.5
, pp. 5128
-
-
Lee, H.-S.1
Lee, S.-A.2
Hur, S.-K.3
Seo, J.-W.4
Kwon, J.5
-
12
-
-
79955934205
-
An emerging model for BAP1?s role in regulating cell cycle progression
-
Eletr Z. M., & Wilkinson K. D. An emerging model for BAP1?s role in regulating cell cycle progression. Cell Biochem. Biophys. 60, 3-11 (2011
-
(2011)
Cell Biochem. Biophys
, vol.60
, pp. 3-11
-
-
Eletr, Z.M.1
Wilkinson, K.D.2
-
13
-
-
64649106796
-
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1
-
Misaghi S., et al. Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1. Mol. Cell Biol. 29, 2181-2192 (2009
-
(2009)
Mol. Cell Biol
, vol.29
, pp. 2181-2192
-
-
Misaghi, S.1
-
14
-
-
84903171180
-
The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex
-
Ji Z., et al. The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. Nucleic Acids Res. 42, 6232-6242 (2014
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 6232-6242
-
-
Ji, Z.1
-
15
-
-
84903215772
-
MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain
-
Baymaz H. I., et al. MBD5 and MBD6 interact with the human PR-DUB complex through their methyl-CpG-binding domain. Proteomics 14, 2179-2189 (2014
-
(2014)
Proteomics
, vol.14
, pp. 2179-2189
-
-
Baymaz, H.I.1
-
16
-
-
9444244427
-
Chromatin compaction by a polycomb group protein complex
-
Francis N. J., Kingston R. E., & Woodcock C. L. Chromatin compaction by a polycomb group protein complex. Science 306, 1574-1577 (2004
-
(2004)
Science
, vol.306
, pp. 1574-1577
-
-
Francis, N.J.1
Kingston, R.E.2
Woodcock, C.L.3
-
17
-
-
77952429798
-
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB
-
Scheuermann J. C., et al. Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature 465, 243-247 (2010
-
(2010)
Nature
, vol.465
, pp. 243-247
-
-
Scheuermann, J.C.1
-
18
-
-
7244234099
-
Role of histone H2A ubiquitination in Polycomb silencing
-
Wang H., et al. Role of histone H2A ubiquitination in Polycomb silencing. Nature 431, 873-878 (2004
-
(2004)
Nature
, vol.431
, pp. 873-878
-
-
Wang, H.1
-
19
-
-
34548420176
-
A genetic screen identifies novel polycomb group genes in Drosophila
-
Gaytán De Ayala Alonso A., et al. A genetic screen identifies novel polycomb group genes in Drosophila. Genetics 176, 2099-2108 (2007
-
(2007)
Genetics
, vol.176
, pp. 2099-2108
-
-
Gaytán De, A.1
Alonso, A.2
-
20
-
-
84934945331
-
Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex
-
Balasubramani A., et al. Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex. Nat. Commun. 6, 7307 (2015
-
(2015)
Nat. Commun
, vol.6
, pp. 7307
-
-
Balasubramani, A.1
-
21
-
-
84938149171
-
Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation
-
Pengelly A. R., Kalb R., Finkl K., & Müller J. Transcriptional repression by PRC1 in the absence of H2A monoubiquitylation. Genes Dev. 29, 1487-1492 (2015
-
(2015)
Genes Dev
, vol.29
, pp. 1487-1492
-
-
Pengelly, A.R.1
Kalb, R.2
Finkl, K.3
Müller, J.4
-
22
-
-
84941956299
-
The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development
-
Illingworth R. S., et al. The E3 ubiquitin ligase activity of RING1B is not essential for early mouse development. Genes Dev. 29, 1897-1902 (2015
-
(2015)
Genes Dev
, vol.29
, pp. 1897-1902
-
-
Illingworth, R.S.1
-
23
-
-
84881108886
-
Functional and cancer genomics of ASXL family members
-
Katoh M. Functional and cancer genomics of ASXL family members. Br. J. Cancer 109, 299-306 (2013
-
(2013)
Br. J. Cancer
, vol.109
, pp. 299-306
-
-
Katoh, M.1
-
24
-
-
79960909421
-
De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome
-
Hoischen A., et al. De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome. Nat. Genet. 43, 729-731 (2011
-
(2011)
Nat. Genet
, vol.43
, pp. 729-731
-
-
Hoischen, A.1
-
25
-
-
84923894408
-
Mechanism of uch-l5 activation and inhibition by deubad domains in rpn13 and ino80g
-
Sahtoe D. D., et al. Mechanism of UCH-L5 Activation and Inhibition by DEUBAD Domains in RPN13 and INO80G. Mol. Cell 57, 887-900 (2015
-
(2015)
Mol. Cell
, vol.57
, pp. 887-900
-
-
Sahtoe, D.D.1
-
26
-
-
84923894407
-
Structural basis for the activation and inhibition of the UCH37 deubiquitylase
-
VanderLinden R. T., et al. Structural basis for the activation and inhibition of the UCH37 deubiquitylase. Mol. Cell 57, 901-911 (2015
-
(2015)
Mol. Cell
, vol.57
, pp. 901-911
-
-
VanderLinden, R.T.1
-
27
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa M. E., Bennett E. J., Gygi S. P., & Harper J. W. Defining the human deubiquitinating enzyme interaction landscape. Cell 138, 389-403 (2009
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
28
-
-
84880931087
-
Deubiquitylases from genes to organism
-
Clague M. J., et al. Deubiquitylases from genes to organism. Physiol. Rev. 93, 1289-1315 (2013
-
(2013)
Physiol. Rev
, vol.93
, pp. 1289-1315
-
-
Clague, M.J.1
-
31
-
-
84855695098
-
The HARE-HTH and associated domains: Novel modules in the coordination of epigenetic DNA and protein modifications
-
Aravind L., & Iyer L. M. The HARE-HTH and associated domains: novel modules in the coordination of epigenetic DNA and protein modifications. Cell Cycle 11, 119-131 (2012
-
(2012)
Cell Cycle
, vol.11
, pp. 119-131
-
-
Aravind, L.1
Iyer, L.M.2
-
32
-
-
0032539582
-
Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes
-
Dang L. C., Melandri F. D., & Stein R. L. Kinetic and mechanistic studies on the hydrolysis of ubiquitin C-terminal 7-amido-4-methylcoumarin by deubiquitinating enzymes. Biochemistry 37, 1868-1879 (1998
-
(1998)
Biochemistry
, vol.37
, pp. 1868-1879
-
-
Dang, L.C.1
Melandri, F.D.2
Stein, R.L.3
-
33
-
-
77957853061
-
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression
-
Yu H., et al. The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression. Mol. Cell Biol. 30, 5071-5085 (2010
-
(2010)
Mol. Cell Biol
, vol.30
, pp. 5071-5085
-
-
Yu, H.1
-
34
-
-
84866388311
-
RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling
-
Mattiroli F., et al. RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA damage signaling. Cell 150, 1182-1195 (2012
-
(2012)
Cell
, vol.150
, pp. 1182-1195
-
-
Mattiroli, F.1
-
35
-
-
84863793933
-
A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase
-
Gatti M., et al. A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase. Cell Cycle 11, 2538-2544 (2012
-
(2012)
Cell Cycle
, vol.11
, pp. 2538-2544
-
-
Gatti, M.1
-
36
-
-
78650446183
-
Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin
-
El Oualid F., et al. Chemical synthesis of ubiquitin, ubiquitin-based probes, and diubiquitin. Angew. Chem. Int. Ed. Engl. 49, 10149-10153 (2010
-
(2010)
Angew. Chem. Int. Ed. Engl
, vol.49
, pp. 10149-10153
-
-
El Oualid, F.1
-
37
-
-
84874612259
-
On terminal alkynes that can react with active-site cysteine nucleophiles in proteases
-
Ekkebus R., et al. On terminal alkynes that can react with active-site cysteine nucleophiles in proteases. J. Am. Chem. Soc. 135, 2867-2870 (2013
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 2867-2870
-
-
Ekkebus, R.1
-
38
-
-
77954285146
-
Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes
-
Shanmugham A., et al. Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes. J. Am. Chem. Soc. 132, 8834-8835 (2010
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 8834-8835
-
-
Shanmugham, A.1
-
39
-
-
52049085265
-
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization
-
Ventii K. H., et al. BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization. Cancer Res. 68, 6953-6962 (2008
-
(2008)
Cancer Res
, vol.68
, pp. 6953-6962
-
-
Ventii, K.H.1
-
40
-
-
84898725334
-
The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A
-
Mattiroli F., Uckelmann M., Sahtoe D. D., van Dijk W. J., & Sixma T. K. The nucleosome acidic patch plays a critical role in RNF168-dependent ubiquitination of histone H2A. Nat. Commun. 5, 3291 (2014
-
(2014)
Nat. Commun
, vol.5
, pp. 3291
-
-
Mattiroli, F.1
Uckelmann, M.2
Sahtoe, D.D.3
Van Dijk, W.J.4
Sixma, T.K.5
-
41
-
-
84908408859
-
Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome
-
McGinty R. K., Henrici R. C., & Tan S. Crystal structure of the PRC1 ubiquitylation module bound to the nucleosome. Nature 514, 591-596 (2014
-
(2014)
Nature
, vol.514
, pp. 591-596
-
-
McGinty, R.K.1
Henrici, R.C.2
Tan, S.3
-
42
-
-
84881279891
-
The role of the nucleosome acidic patch in modulating higher order chromatin structure
-
Kalashnikova A. A., Porter-Goff M. E., Muthurajan U. M., Luger K., & Hansen J. C. The role of the nucleosome acidic patch in modulating higher order chromatin structure. J. R. Soc. Interface 10, 20121022 (2013
-
(2013)
J. R. Soc. Interface
, vol.10
, pp. 20121022
-
-
Kalashnikova, A.A.1
Porter-Goff, M.E.2
Muthurajan, U.M.3
Luger, K.4
Hansen, J.C.5
-
43
-
-
84969316311
-
The BAP1/ASXL2 histone H2A deubiquitinase complex regulates cell proliferation and is disrupted in cancer
-
Daou S., et al. The BAP1/ASXL2 histone H2A deubiquitinase complex regulates cell proliferation and is disrupted in cancer. J. Biol. Chem. M115, 661553 (2015
-
(2015)
J. Biol. Chem M
, vol.115
, pp. 661553
-
-
Daou, S.1
-
44
-
-
84899905723
-
Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O
-
Mashtalir N., et al. Autodeubiquitination protects the tumor suppressor BAP1 from cytoplasmic sequestration mediated by the atypical ubiquitin ligase UBE2O. Mol. Cell 54, 392-406 (2014
-
(2014)
Mol. Cell
, vol.54
, pp. 392-406
-
-
Mashtalir, N.1
-
45
-
-
79959549028
-
Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases
-
Luna-Vargas M. P. A., et al. Enabling high-throughput ligation-independent cloning and protein expression for the family of ubiquitin specific proteases. J. Struct. Biol. 175, 113-119 (2011
-
(2011)
J. Struct. Biol
, vol.175
, pp. 113-119
-
-
Luna-Vargas, M.P.A.1
-
46
-
-
0033289822
-
Expression and purification of recombinant histones and nucleosome reconstitution
-
Luger K., Rechsteiner T. J., & Richmond T. J. Expression and purification of recombinant histones and nucleosome reconstitution. Methods Mol. Biol. 119, 1-16 (1999
-
(1999)
Methods Mol. Biol
, vol.119
, pp. 1-16
-
-
Luger, K.1
Rechsteiner, T.J.2
Richmond, T.J.3
-
47
-
-
1542334851
-
Reconstitution of nucleosome core particles from recombinant histones and DNA
-
Dyer P. N., et al. Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods Enzymol. 375, 23-44 (2004
-
(2004)
Methods Enzymol
, vol.375
, pp. 23-44
-
-
Dyer, P.N.1
-
48
-
-
0032512794
-
New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning
-
Lowary P. T., & Widom J. New DNA sequence rules for high affinity binding to histone octamer and sequence-directed nucleosome positioning. J. Mol. Biol. 276, 19-42 (1998
-
(1998)
J. Mol. Biol
, vol.276
, pp. 19-42
-
-
Lowary, P.T.1
Widom, J.2
-
49
-
-
84928597157
-
Tristriazole ligand for use in the Cu-Catalyzed [3+2] azide-alkyne cycloaddition on protein surfaces
-
Kramer H. B., Chalker J. M., & Davis B. G. Tristriazole ligand for use in the Cu-Catalyzed [3+2] azide-alkyne cycloaddition on protein surfaces. Protoc. Exch. (2007
-
(2007)
Protoc. Exch
-
-
Kramer, H.B.1
Chalker, J.M.2
Davis, B.G.3
-
50
-
-
84855873408
-
A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents
-
Geurink P. P., El Oualid F., Jonker A., Hameed D. S., & Ovaa H. A general chemical ligation approach towards isopeptide-linked ubiquitin and ubiquitin-like assay reagents. Chembiochem 13, 293-297 (2012
-
(2012)
Chembiochem
, vol.13
, pp. 293-297
-
-
Geurink, P.P.1
El Oualid, F.2
Jonker, A.3
Hameed, D.S.4
Ovaa, H.5
-
51
-
-
45949107473
-
Recent developments in the MAFFT multiple sequence alignment program
-
Katoh K., & Toh H. Recent developments in the MAFFT multiple sequence alignment program. Brief. Bioinform. 9, 286-298 (2008
-
(2008)
Brief. Bioinform
, vol.9
, pp. 286-298
-
-
Katoh, K.1
Toh, H.2
-
52
-
-
23144448512
-
ConSurf 2005: The projection of evolutionary conservation scores of residues on protein structures
-
Landau M., et al. ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures. Nucleic Acids Res. 33, W299-W302 (2005
-
(2005)
Nucleic Acids Res
, vol.33
, pp. W299-W302
-
-
Landau, M.1
-
53
-
-
13444307044
-
Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions
-
Krissinel E., & Henrick K. Secondary-structure matching (SSM), a new tool for fast protein structure alignment in three dimensions. Acta Crystallogr. D. Biol. Crystallogr. 60, 2256-2268 (2004
-
(2004)
Acta Crystallogr. D. Biol. Crystallogr
, vol.60
, pp. 2256-2268
-
-
Krissinel, E.1
Henrick, K.2
|