Mechanism of UCH-L5 Activation and Inhibition by DEUBAD Domains in RPN13 and INO80G

Molecular Cell

Volumn 57, Issue 5, 2015, Pages 887-900

  Sahtoe, Danny D ^a   vanDijk, Willem J ^a   ElOualid, Farid ^a,b   Ekkebus, Reggy ^a   Ovaa, Huib ^a   Sixma, Titia K ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b UbiQ Bio BV   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DEUBIQUITINASE; DEUBIQUITINATING ENZYME UCH L5; INHIBITOR PROTEIN; REGULATOR PROTEIN; REGULATORY PROTEIN INO80G; REGULATORY PROTEIN RPN13; UNCLASSIFIED DRUG; ADRM1 PROTEIN, HUMAN; DNA BINDING PROTEIN; MEMBRANE PROTEIN; NFRKB PROTEIN, HUMAN; PROTEIN BINDING; UBIQUITIN; UBIQUITIN THIOLESTERASE; UCHL5 PROTEIN, HUMAN;

ALLOSTERISM; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CONFORMATIONAL TRANSITION; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME INHIBITION; ENZYME MECHANISM; ENZYME STRUCTURE; GENETIC CONSERVATION; HUMAN; MOLECULAR DOCKING; MOLECULAR MIMICRY; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME SPECIFICITY; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE HOMOLOGY; X RAY CRYSTALLOGRAPHY;

EUKARYOTA;

AMINO ACID SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; MEMBRANE GLYCOPROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; UBIQUITIN; UBIQUITIN THIOLESTERASE;

EID: 84923894408     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.12.039     Document Type: Article

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