Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation

EMBO Journal

Volumn 31, Issue 19, 2012, Pages 3856-3870

  Tokunaga, Fuminori ^a,b   Nishimasu, Hiroshi ^c   Ishitani, Ryuichiro ^c   Goto, Eiji ^a   Noguchi, Takuya ^a   Mio, Kazuhiro ^d   Kamei, Kiyoko ^a,b   Ma, Averil ^e   Iwai, Kazuhiro ^b,f,g   Nureki, Osamu ^c  

^a GUNMA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f OSAKA UNIVERSITY   (Japan)

^g KYOTO UNIVERSITY   (Japan)

Author keywords

A20; deubiquitinase; lymphoma; NF B; ubiquitin

Indexed keywords

A20 ZINC FINGER 7 PROTEIN; CYLD PROTEIN; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX; NUCLEIC ACID BINDING PROTEIN; POLYUBIQUITIN; TUMOR NECROSIS FACTOR RECEPTOR; UBIQUITIN; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVATION; ENZYME REPRESSION; ENZYME SUBSTRATE COMPLEX; HUMAN; HUMAN CELL; IMMUNOREGULATION; INFLAMMATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UBIQUITINATION;

CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; I-KAPPA B KINASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOMA, B-CELL; MUTATION; NF-KAPPA B; NUCLEAR PROTEINS; POLYUBIQUITIN; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, TUMOR NECROSIS FACTOR; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN; ZINC FINGERS;

EID: 84867043680     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.241     Document Type: Article

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