A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7

EMBO Journal

Volumn 31, Issue 19, 2012, Pages 3845-3855

  Verhelst, Kelly ^a,b   Carpentier, Isabelle ^a,b   Kreike, Marja ^a,b   Meloni, Laura ^a,b   Verstrepen, Lynn ^a,b   Kensche, Tobias ^c   Dikic, Ivan ^c,d   Beyaert, Rudi ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c GOETHE UNIVERSITY MEDICAL SCHOOL   (Germany)

^d GOETHE UNIVERSITY   (Germany)

Author keywords

A20; NF kB; TNFAIP3; ubiquitin; zinc finger

Indexed keywords

A20 PROTEIN; BINDING PROTEIN; I KAPPA B KINASE GAMMA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LINEAR UBIQUITIN CHAIN ASSEMBLY COMPLEX; LUBID PROTEIN; POLYPEPTIDE; POLYUBIQUITIN; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR ALPHA; UBIQUITIN; UNCLASSIFIED DRUG; ZINC FINGER 7 PROTEIN; ZINC FINGER PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDIATOR; POLYUBIQUITINATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION;

DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; I-KAPPA B KINASE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NF-KAPPA B; NUCLEAR PROTEINS; POLYUBIQUITIN; PROTEIN BINDING; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA; ZINC FINGERS;

EID: 84867062977     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2012.240     Document Type: Article

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