Polyubiquitin binding and cross-reactivity in the USP domain deubiquitinase USP21

EMBO Reports

Volumn 12, Issue 4, 2011, Pages 350-357

  Ye, Yu ^a   Akutsu, Masato ^a   Reyes Turcu, Francisca ^b,d   Enchev, Radoslav I ^c,e   Wilkinson, Keith D ^b   Komander, David ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^d NATIONAL CANCER INSTITUTE   (United States)

^e ETH ZURICH   (Switzerland)

Author keywords

cross reactivity; linkage specificity; NEDD8; SG15; ubiquitin specific protease

Indexed keywords

ALDEHYDE; INTERFERON STIMULATED GENE FACTOR 15; NEDD8 PROTEIN; POLYUBIQUITIN; TRANSCRIPTION FACTOR; UBIQUITIN; UBIQUITIN SPECIFIC PROTEASE 21; UNCLASSIFIED DRUG;

ARTICLE; CROSS REACTION; ENZYME MODIFICATION; ENZYME SPECIFICITY; HUMAN; HYDROLYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN INTERACTION; PROTEIN STRUCTURE; PROTEIN TARGETING; UBIQUITINATION;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYTOKINES; HUMANS; POLYUBIQUITIN; PROTEIN BINDING; UBIQUITIN THIOLESTERASE; UBIQUITINS;

EID: 79953314427     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2011.17     Document Type: Article

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