The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains

Journal of Biological Chemistry

Volumn 283, Issue 39, 2008, Pages 26436-26443

  Winborn, Brett J ^b   Travis, Sue M ^a   Todi, Sokol V ^b   Scaglione, K Matthew ^b   Xu, Ping ^c   Williams, Aislinn J ^d   Cohen, Robert E ^e   Peng, Junmin ^c   Paulson, Henry L ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d The University of Iowa   (United States)

^e JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CHAINS; ENZYME ACTIVITY; ENZYMES; FLOW INTERACTIONS; PORT TERMINALS;

CATALYTIC DOMAINS; DEUBIQUITINATING ENZYMES; DO-MAINS; IN CELLS; LINKED CHAINS; POLYGLUTAMINE; POLYGLUTAMINE DISEASES; POLYUBIQUITIN; UBIQUITIN; UBIQUITIN INTERACTION MOTIFS;

PROTEINS;

ATAXIN 3; LYSINE; POLYGLUTAMINE; POLYUBIQUITIN; PROTEINASE; UBIQUITIN; ATXN3 PROTEIN, HUMAN; NERVE PROTEIN; NUCLEAR PROTEIN; PEPTIDE; REPRESSOR PROTEIN; UBIQUITIN THIOLESTERASE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN FUNCTION; PROTEIN INTERACTION; UBIQUITINATION; CELL LINE; DEMYELINATING DISEASE; ENZYMOLOGY; GENETICS; HUMAN; METABOLIC ENCEPHALOPATHY; METABOLISM; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE;

AMINO ACID MOTIFS; BRAIN DISEASES, METABOLIC, INBORN; CELL LINE; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; REPRESSOR PROTEINS; UBIQUITIN; UBIQUITIN THIOLESTERASE;

EID: 55549086868     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803692200     Document Type: Article

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