Mechanism of USP7/HAUSP activation by its C-Terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase

Molecular Cell

Volumn 44, Issue 1, 2011, Pages 147-159

  Faesen, Alex C ^a   Dirac, Annette M G ^a   Shanmugham, Anitha ^a   Ovaa, Huib ^a   Perrakis, Anastassis ^a   Sixma, Titia K ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE PHOSPHATE SYNTHETASE; PROTEINASE; SYNTHETASE; UBIQUITIN; UBIQUITIN SPECIFIC PROTEASE 7; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME REGULATION; IN VITRO STUDY; IN VIVO STUDY; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN INTERACTION;

ALLOSTERIC SITE; CARBON-NITROGEN LIGASES; CATALYTIC DOMAIN; CELL LINE, TUMOR; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KINETICS; POINT MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITIN; UBIQUITIN THIOLESTERASE;

EID: 80053594090     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2011.06.034     Document Type: Article

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