CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN

Cell Reports

Volumn 15, Issue 11, 2016, Pages 2449-2461

  Legarda, Diana ^a   Justus, Scott J ^a   Ang, Rosalind L ^a   Rikhi, Nimisha ^a   Li, Wenjing ^a   Moran, Thomas M ^a   Zhang, Jianke ^b   Mizoguchi, Emiko ^c   Zelic, Matija ^d   Kelliher, Michelle A ^d   Blander, J Magarian ^a   Ting, Adrian T ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; ALPHA INTERFERON; BETA INTERFERON; CASPASE 8; CYLINDROMATOSIS PROTEIN; DEUBIQUITINASE; INTERFERON; LIPOPOLYSACCHARIDE; MIXED LINEAGE KINASE; MLKL PROTEIN; RIPK1 PROTEIN; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG; CYLD PROTEIN, MOUSE; CYSTEINE PROTEINASE; MLKL PROTEIN, MOUSE; PROTEIN KINASE; TICAM-1 PROTEIN, MOUSE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; CYTOKINE PRODUCTION; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; BIOLOGICAL MODEL; C57BL MOUSE; CELL PROTECTION; MACROPHAGE; METABOLISM; NECROSIS; TRANSGENIC MOUSE;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; CASPASE 8; CYSTEINE ENDOPEPTIDASES; CYTOPROTECTION; INTERFERON TYPE I; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MODELS, BIOLOGICAL; NECROSIS; PROTEIN KINASES; PROTEOLYSIS; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84974694612     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.05.032     Document Type: Article

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