Exosomes from NSC-34 cells transfected with hSOD1-G93A are enriched in mir-124 and drive alterations in microglia phenotype

Frontiers in Neuroscience

Volumn 11, Issue MAY, 2017, Pages

  Pinto, Sara ^a   Cunha, Carolina ^a   Barbosa, Marta ^a   Vaz, Ana R ^a   Brites, Dora ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

Author keywords

Amyotrophic lateral sclerosis; Inflamma microRNA; Microglia polarization; Microglia surface receptors; MN derived exosomes; Motor neurons (MNs); Mutant SOD1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; COPPER ZINC SUPEROXIDE DISMUTASE 1; GELATINASE A; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA 124; MICRORNA 146A; MICRORNA 155; NITRIC OXIDE; UNCLASSIFIED DRUG;

AMYOTROPHIC LATERAL SCLEROSIS; ARGINASE 1 GENE; ARTICLE; CELL PHAGOCYTOSIS; CONTROLLED STUDY; EXOSOME; GENE; IL 10 GENE; IL 1BETA GENE; INFLAMMATION; INOS GENE; MHC II GENE; MICROGLIA; MOTONEURON; NERVE DEGENERATION; RAGE GENE; SENESCENCE; TLR4 GENE; TNF ALPHA GENE; TREM2 GENE;

EID: 85019549415     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2017.00273     Document Type: Article

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