-
1
-
-
0035833937
-
Immune reactivity in a mouse model of familial ALS correlates with disease progression
-
11591849 10.1212/WNL.57.7.1282 1:STN:280:DC%2BD3MrksVyhug%3D%3D
-
Alexianu ME, Kozovska M, Appel SH (2001) Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57:1282-1289
-
(2001)
Neurology
, vol.57
, pp. 1282-1289
-
-
Alexianu, M.E.1
Kozovska, M.2
Appel, S.H.3
-
2
-
-
73149116008
-
T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: Are we listening?
-
19879804 10.1016/j.it.2009.09.003 1:CAS:528:DC%2BC3cXkt1ejtQ%3D%3D
-
Appel SH, Beers DR, Henkel JS (2010) T cell-microglial dialogue in Parkinson's disease and amyotrophic lateral sclerosis: are we listening? Trends Immunol 31:7-17
-
(2010)
Trends Immunol
, vol.31
, pp. 7-17
-
-
Appel, S.H.1
Beers, D.R.2
Henkel, J.S.3
-
3
-
-
80052967905
-
TDP-43: The relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration
-
21777387 10.1111/j.1742-4658.2011.08256.x 1:CAS:528:DC%2BC3MXht1Ons7nM
-
Baloh RH (2011) TDP-43: the relationship between protein aggregation and neurodegeneration in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. FEBS J 278:3539-3549
-
(2011)
FEBS J
, vol.278
, pp. 3539-3549
-
-
Baloh, R.H.1
-
4
-
-
50549098607
-
Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice
-
18648532 10.1371/journal.pone.0002740
-
Banerjee R, Mosley RL, Reynolds AD, Dhar A, Jackson-Lewis V, Gordon PH, Przedborski S, Gendelman HE (2008) Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice. PLoS One 3:e2740
-
(2008)
PLoS One
, vol.3
, pp. 2740
-
-
Banerjee, R.1
Mosley, R.L.2
Reynolds, A.D.3
Dhar, A.4
Jackson-Lewis, V.5
Gordon, P.H.6
Przedborski, S.7
Gendelman, H.E.8
-
5
-
-
56949098606
-
Requirement of myeloid cells for axon regeneration
-
18799670 10.1523/JNEUROSCI.1447-08.2008 1:CAS:528:DC%2BD1cXht1SgtrzJ
-
Barrette B, Hébert MA, Filali M, Lafortune K, Vallières N, Gowing G, Julien JP, Lacroix S (2008) Requirement of myeloid cells for axon regeneration. J Neurosci 28:9363-9376
-
(2008)
J Neurosci
, vol.28
, pp. 9363-9376
-
-
Barrette, B.1
Hébert, M.A.2
Filali, M.3
Lafortune, K.4
Vallières, N.5
Gowing, G.6
Julien, J.P.7
Lacroix, S.8
-
6
-
-
33750478657
-
Wild-type microglia extends survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
-
17043238 10.1073/pnas.0607423103 1:CAS:528:DC%2BD28XhtFyku7nE
-
Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklós L, McKercher SR, Appel SH (2006) Wild-type microglia extends survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 103:16021-16026
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16021-16026
-
-
Beers, D.R.1
Henkel, J.S.2
Xiao, Q.3
Zhao, W.4
Wang, J.5
Yen, A.A.6
Siklós, L.7
McKercher, S.R.8
Appel, S.H.9
-
7
-
-
55749110043
-
CD4+ T-cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS
-
18809917 10.1073/pnas.0807419105 1:CAS:528:DC%2BD1cXht1Gnt7rO
-
Beers DR, Henkel JS, Zhao W, Wang J, Appel SH (2008) CD4+ T-cells support glial neuroprotection, slow disease progression, and modify glial morphology in an animal model of inherited ALS. Proc Natl Acad Sci U S A 105:15558-15563
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 15558-15563
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Appel, S.H.5
-
8
-
-
79957528028
-
Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis
-
21596768 10.1093/brain/awr074
-
Beers DR, Henkel JS, Zhao W, Wang J, Huang A, Wen S, Liao B, Appel SH (2011a) Endogenous regulatory T lymphocytes ameliorate amyotrophic lateral sclerosis in mice and correlate with disease progression in patients with amyotrophic lateral sclerosis. Brain 134:1293-1314
-
(2011)
Brain
, vol.134
, pp. 1293-1314
-
-
Beers, D.R.1
Henkel, J.S.2
Zhao, W.3
Wang, J.4
Huang, A.5
Wen, S.6
Liao, B.7
Appel, S.H.8
-
9
-
-
79957927732
-
Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice
-
21176785 10.1016/j.bbi.2010.12.008 1:CAS:528:DC%2BC3MXntlGlu7w%3D
-
Beers DR, Zhao W, Liao B, Kano O, Wang J, Huang A, Appel SH, Henkel JS (2011b) Neuroinflammation modulates distinct regional and temporal clinical responses in ALS mice. Brain Behav Immun 25:1025-1035
-
(2011)
Brain Behav Immun
, vol.25
, pp. 1025-1035
-
-
Beers, D.R.1
Zhao, W.2
Liao, B.3
Kano, O.4
Wang, J.5
Huang, A.6
Appel, S.H.7
Henkel, J.S.8
-
10
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
-
16648838 10.1038/nature04753 1:CAS:528:DC%2BD28XksVGns7g%3D
-
Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK (2006) Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 441:235-238
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
11
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
16741123 10.1126/science.1123511
-
Boillée S, Yamanaka K, Lobsiger CS, Copeland NG, Jenkins NA, Kassiotis G, Kollias G, Cleveland DW (2006) Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312:1389-1392
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillée, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
Kollias, G.7
Cleveland, D.W.8
-
12
-
-
77958519939
-
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
-
20953194 10.1038/nn.2660 1:CAS:528:DC%2BC3cXhtlSgur7O
-
Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH Jr (2010) Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci 13:1396-1403
-
(2010)
Nat Neurosci
, vol.13
, pp. 1396-1403
-
-
Bosco, D.A.1
Morfini, G.2
Karabacak, N.M.3
Song, Y.4
Gros-Louis, F.5
Pasinelli, P.6
Goolsby, H.7
Fontaine, B.A.8
Lemay, N.9
McKenna-Yasek, D.10
Frosch, M.P.11
Agar, J.N.12
Julien, J.P.13
Brady, S.T.14
Brown, Jr.R.H.15
-
13
-
-
0001930725
-
Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli
-
10648003 1:CAS:528:DC%2BD3cXmt1Siuw%3D%3D
-
Buechler C, Ritter M, Orsó E, Langmann T, Klucken J, Schmitz G (2000) Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli. J Leukoc Biol 67:97-103
-
(2000)
J Leukoc Biol
, vol.67
, pp. 97-103
-
-
Buechler, C.1
Ritter, M.2
Orsó, E.3
Langmann, T.4
Klucken, J.5
Schmitz, G.6
-
14
-
-
84865987121
-
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
-
22863620 10.1172/JCI62636 1:CAS:528:DC%2BC38XhtlChsbrL
-
Butovsky O, Siddiqui S, Gabriely G, Lanser AJ, Dake B, Murugaiyan G, Doykan CE, Wu PM, Gali RR, Iyer LK, Lawson R, Berry J, Krichevsky AM, Cudkowicz ME, Weiner HL (2012) Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J Clin Invest 122:3063-3087
-
(2012)
J Clin Invest
, vol.122
, pp. 3063-3087
-
-
Butovsky, O.1
Siddiqui, S.2
Gabriely, G.3
Lanser, A.J.4
Dake, B.5
Murugaiyan, G.6
Doykan, C.E.7
Wu, P.M.8
Gali, R.R.9
Iyer, L.K.10
Lawson, R.11
Berry, J.12
Krichevsky, A.M.13
Cudkowicz, M.E.14
Weiner, H.L.15
-
15
-
-
56649100689
-
T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS
-
18997009 10.1073/pnas.0804610105 1:CAS:528:DC%2BD1cXhsVCmurvJ
-
Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TH, Brown RH Jr, Carroll MC (2008) T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS. Proc Natl Acad Sci USA 105:17913-17918
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 17913-17918
-
-
Chiu, I.M.1
Chen, A.2
Zheng, Y.3
Kosaras, B.4
Tsiftsoglou, S.A.5
Vartanian, T.H.6
Brown, Jr.R.H.7
Carroll, M.C.8
-
16
-
-
73949128974
-
Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice
-
19933335 10.1073/pnas.0911405106 1:CAS:528:DC%2BC3cXltVGltQ%3D%3D
-
Chiu IM, Phatnani H, Kuligowski M, Tapia JC, Carrasco MA, Zhang M, Maniatis T, Carroll MC (2009) Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice. Proc Natl Acad Sci U S A 106:20960-20965
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 20960-20965
-
-
Chiu, I.M.1
Phatnani, H.2
Kuligowski, M.3
Tapia, J.C.4
Carrasco, M.A.5
Zhang, M.6
Maniatis, T.7
Carroll, M.C.8
-
17
-
-
0141642203
-
Wild-type noneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
-
14526083 10.1126/science.1086071 1:CAS:528:DC%2BD3sXnslSjsLo%3D
-
Clement AM, Nguyen MD, Roberts EA, Garcia ML, Boillee S, Rule M, McMahon AP, Doucette W, Siwek D, Ferrante RJ, Brown RH, Julien J-P, Goldstein LSB, Cleveland DW (2003) Wild-type noneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science 302:113-117
-
(2003)
Science
, vol.302
, pp. 113-117
-
-
Clement, A.M.1
Nguyen, M.D.2
Roberts, E.A.3
Garcia, M.L.4
Boillee, S.5
Rule, M.6
McMahon, A.P.7
Doucette, W.8
Siwek, D.9
Ferrante, R.J.10
Brown, R.H.11
Julien, J.-P.12
Goldstein, L.S.B.13
Cleveland, D.W.14
-
18
-
-
84871756816
-
Molecular imaging of microglial activation in amyotrophic lateral sclerosis
-
23300829 10.1371/journal.pone.0052941 1:CAS:528:DC%2BC3sXptVSgtg%3D%3D
-
Corcia P, Tauber C, Vercoullie J et al (2012) Molecular imaging of microglial activation in amyotrophic lateral sclerosis. PLoS One 7:e52941
-
(2012)
PLoS One
, vol.7
, pp. 52941
-
-
Corcia, P.1
Tauber, C.2
Vercoullie, J.3
-
19
-
-
84155171976
-
Understanding the role of TDP-43 and FUS/TLS in ALS and beyond
-
21813273 10.1016/j.conb.2011.05.029
-
Da Cruz S, Cleveland DW (2011) Understanding the role of TDP-43 and FUS/TLS in ALS and beyond. Curr Opin Neurobiol 21:904-919
-
(2011)
Curr Opin Neurobiol
, vol.21
, pp. 904-919
-
-
Da Cruz, S.1
Cleveland, D.W.2
-
20
-
-
80054832080
-
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
-
21944778 10.1016/j.neuron.2011.09.011 1:CAS:528:DC%2BC3MXhtlKrtL%2FP
-
DeJesus-Hernandez M, Mackenzie IR, Boeve BF et al (2011) Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS. Neuron 72:245-256
-
(2011)
Neuron
, vol.72
, pp. 245-256
-
-
Dejesus-Hernandez, M.1
Mackenzie, I.R.2
Boeve, B.F.3
-
21
-
-
44349162407
-
Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity
-
18388910 10.1038/mt.2008.60 1:CAS:528:DC%2BD1cXmt1Oku70%3D
-
Dodge JC, Haidet AM, Yang W, Passini MA, Hester M, Clarke J, Roskelley EM, Treleaven CM, Rizo L, Martin H, Kim SH, Kaspar R, Taksir TV, Griffiths DA, Cheng SH, Shihabuddin LS, Kaspar BK (2008) Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity. Mol Ther 16:1056-1064
-
(2008)
Mol Ther
, vol.16
, pp. 1056-1064
-
-
Dodge, J.C.1
Haidet, A.M.2
Yang, W.3
Passini, M.A.4
Hester, M.5
Clarke, J.6
Roskelley, E.M.7
Treleaven, C.M.8
Rizo, L.9
Martin, H.10
Kim, S.H.11
Kaspar, R.12
Taksir, T.V.13
Griffiths, D.A.14
Cheng, S.H.15
Shihabuddin, L.S.16
Kaspar, B.K.17
-
22
-
-
0033555806
-
Synthesis of the antioxidant glutathione in neurons: Supply by astrocytes of CysGly as precursor for neuronal glutathione
-
9880576 1:CAS:528:DyaK1MXltlagtA%3D%3D
-
Dringen R, Pfeiffer B, Hamprecht B (1999) Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione. J Neurosci 19:562-569
-
(1999)
J Neurosci
, vol.19
, pp. 562-569
-
-
Dringen, R.1
Pfeiffer, B.2
Hamprecht, B.3
-
23
-
-
34250177650
-
Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation
-
17394546 10.1111/j.1471-4159.2007.04531.x
-
Ezzi SA, Urushitani M, Julien JP (2007) Wild-type superoxide dismutase acquires binding and toxic properties of ALS-linked mutant forms through oxidation. J Neurochem 102:170-178
-
(2007)
J Neurochem
, vol.102
, pp. 170-178
-
-
Ezzi, S.A.1
Urushitani, M.2
Julien, J.P.3
-
24
-
-
79960987739
-
Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS
-
21829620 10.1371/journal.pone.0022374 1:CAS:528:DC%2BC3MXhtV2mtLjN
-
Finkelstein A, Kunis G, Seksenyan A, Ronen A, Berkutzki T, Azoulay D, Koronyo-Hamaoui M, Schwartz M (2011) Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS. PLoS One 6:e22374
-
(2011)
PLoS One
, vol.6
, pp. 22374
-
-
Finkelstein, A.1
Kunis, G.2
Seksenyan, A.3
Ronen, A.4
Berkutzki, T.5
Azoulay, D.6
Koronyo-Hamaoui, M.7
Schwartz, M.8
-
25
-
-
0345742771
-
Amyotrophic lateral sclerosis is a distal axonopathy: Evidence in mice and man
-
14736504 10.1016/j.expneurol.2003.10.004
-
Fischer LR, Culver DG, Tennant P, Davis AA, Wang M, Castellano-Sanchez A, Khan J, Polak MA, Glass JD (2004) Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man. Exp Neurol 185:232-240
-
(2004)
Exp Neurol
, vol.185
, pp. 232-240
-
-
Fischer, L.R.1
Culver, D.G.2
Tennant, P.3
Davis, A.A.4
Wang, M.5
Castellano-Sanchez, A.6
Khan, J.7
Polak, M.A.8
Glass, J.D.9
-
26
-
-
84865174013
-
Animal models of MS reveal multiple roles of microglia in disease pathogenesis
-
doi: 10.1155/2011/383087
-
Gao Z,Tsirka SE (2011) Animal models of MS reveal multiple roles of microglia in disease pathogenesis. Neurol Res Int. doi: 10.1155/2011/383087
-
(2011)
Neurol Res Int.
-
-
Gao, Z.1
Tsirka, S.E.2
-
27
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
20510870 10.1016/j.immuni.2010.05.007 1:CAS:528:DC%2BC3cXnt1Kls78%3D
-
Gordon S, Martinez FO (2010) Alternative activation of macrophages: mechanism and functions. Immunity 32:593-604
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
28
-
-
84859454704
-
An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1
-
22416121 10.1073/pnas.1115402109 1:CAS:528:DC%2BC38Xlt1Sisr4%3D
-
Guareschi S, Cova E, Cereda C, Ceroni M, Donetti E, Bosco DA, Trotti D, Pasinelli P (2012) An over-oxidized form of superoxide dismutase found in sporadic amyotrophic lateral sclerosis with bulbar onset shares a toxic mechanism with mutant SOD1. Proc Natl Acad Sci U S A 109:5074-5079
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 5074-5079
-
-
Guareschi, S.1
Cova, E.2
Cereda, C.3
Ceroni, M.4
Donetti, E.5
Bosco, D.A.6
Trotti, D.7
Pasinelli, P.8
-
29
-
-
80052783545
-
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
-
21832997 10.1038/nbt.1957 1:CAS:528:DC%2BC3MXpvF2isrw%3D
-
Haidet-Phillips AM, Hester ME, Miranda CJ, Meyer K, Braun L, Frakes A, Song S, Likhite S, Murtha MJ, Foust KD, Rao M, Eagle A, Kammesheidt A, Christensen A, Mendell JR, Burghes AH, Kaspar BK (2011) Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat Biotechnol 29:824-828
-
(2011)
Nat Biotechnol
, vol.29
, pp. 824-828
-
-
Haidet-Phillips, A.M.1
Hester, M.E.2
Miranda, C.J.3
Meyer, K.4
Braun, L.5
Frakes, A.6
Song, S.7
Likhite, S.8
Murtha, M.J.9
Foust, K.D.10
Rao, M.11
Eagle, A.12
Kammesheidt, A.13
Christensen, A.14
Mendell, J.R.15
Burghes, A.H.16
Kaspar, B.K.17
-
30
-
-
10744229158
-
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
-
14755726 10.1002/ana.10805 1:CAS:528:DC%2BD2cXhs1SgtbY%3D
-
Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH (2004) Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol 55:221-235
-
(2004)
Ann Neurol
, vol.55
, pp. 221-235
-
-
Henkel, J.S.1
Engelhardt, J.I.2
Siklos, L.3
Simpson, E.P.4
Kim, S.H.5
Pan, T.6
Goodman, J.C.7
Siddique, T.8
Beers, D.R.9
Appel, S.H.10
-
31
-
-
33644821966
-
The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS
-
16337133 10.1016/j.mcn.2005.10.016 1:CAS:528:DC%2BD28Xit1CmtLw%3D
-
Henkel JH, Beers DR, Siklós L, Appel SH (2006) The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol Cell Neurosci 31:427-437
-
(2006)
Mol Cell Neurosci
, vol.31
, pp. 427-437
-
-
Henkel, J.H.1
Beers, D.R.2
Siklós, L.3
Appel, S.H.4
-
32
-
-
84871988603
-
Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival
-
23143995 10.1002/emmm.201201544 1:CAS:528:DC%2BC3sXntFWl
-
Henkel JS, Beers DR, Wen S, Rivera AL, Toennis KM, Appel JE, Zhao W, Moore DH, Powell SZ, Appel SH (2013) Regulatory T-lymphocytes mediate amyotrophic lateral sclerosis progression and survival. EMBO Mol Med 5:64-79
-
(2013)
EMBO Mol Med
, vol.5
, pp. 64-79
-
-
Henkel, J.S.1
Beers, D.R.2
Wen, S.3
Rivera, A.L.4
Toennis, K.M.5
Appel, J.E.6
Zhao, W.7
Moore, D.H.8
Powell, S.Z.9
Appel, S.H.10
-
33
-
-
41149088328
-
T cells in amyotrophic lateral sclerosis
-
18266871 10.1111/j.1468-1331.2008.02065.x
-
Holmøy T (2008) T cells in amyotrophic lateral sclerosis. Eur J Neurol 15:360-366
-
(2008)
Eur J Neurol
, vol.15
, pp. 360-366
-
-
Holmøy, T.1
-
34
-
-
82355170711
-
Molecular pathology and genetic advances in amyotrophic lateral sclerosis: An emerging molecular pathway and the significance of glial pathology
-
22105541 10.1007/s00401-011-0913-0 1:CAS:528:DC%2BC3MXhsFCms7%2FP
-
Ince PG, Highley JR, Kirby J, Wharton SB, Takahashi H, Strong MJ, Shaw PJ (2011) Molecular pathology and genetic advances in amyotrophic lateral sclerosis: an emerging molecular pathway and the significance of glial pathology. Acta Neuropathol 122:657-671
-
(2011)
Acta Neuropathol
, vol.122
, pp. 657-671
-
-
Ince, P.G.1
Highley, J.R.2
Kirby, J.3
Wharton, S.B.4
Takahashi, H.5
Strong, M.J.6
Shaw, P.J.7
-
35
-
-
39849103473
-
Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
-
18305242 10.1523/JNEUROSCI.5258-07.2008 1:CAS:528:DC%2BD1cXjt1Cqtb8%3D
-
Jaarsma D, Teuling E, Haasdijk ED, De Zeeuw CI, Hoogenraad CC (2008) Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J Neurosci 28:2075-2088
-
(2008)
J Neurosci
, vol.28
, pp. 2075-2088
-
-
Jaarsma, D.1
Teuling, E.2
Haasdijk, E.D.3
De Zeeuw, C.I.4
Hoogenraad, C.C.5
-
36
-
-
37249011467
-
MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis
-
18086918 10.1083/jcb.200705046 1:CAS:528:DC%2BD2sXhsVOgtL%2FM
-
Kang J, Rivest S (2007) MyD88-deficient bone marrow cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis. J Cell Biol 179:1219-1230
-
(2007)
J Cell Biol
, vol.179
, pp. 1219-1230
-
-
Kang, J.1
Rivest, S.2
-
37
-
-
84859936249
-
Peripheral nerve inflammation in ALS mice: Cause or consequence
-
22377817 10.1212/WNL.0b013e318249f776
-
Kano O, Beers DR, Henkel JS, Appel SH (2012) Peripheral nerve inflammation in ALS mice: cause or consequence. Neurology 78:833-835
-
(2012)
Neurology
, vol.78
, pp. 833-835
-
-
Kano, O.1
Beers, D.R.2
Henkel, J.S.3
Appel, S.H.4
-
38
-
-
0042528664
-
Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model
-
10.1126/science.1086137 1:CAS:528:DC%2BD3sXmtVGqs7c%3D
-
Kaspar BK, Llado J, Sherkat N, Rothstein JD, Gage FH (2003) Retrograde viral delivery of IGF-1 prolongs survival in a mouse ALS model. Sciencen 301:839-842
-
(2003)
Sciencen
, vol.301
, pp. 839-842
-
-
Kaspar, B.K.1
Llado, J.2
Sherkat, N.3
Rothstein, J.D.4
Gage, F.H.5
-
39
-
-
36448942946
-
Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS
-
17963733 10.1016/j.brainres.2007.09.034 1:CAS:528:DC%2BD2sXhtlykurrM
-
Lepore AC, Haenggeli C, Gasmi M, Bishop KM, Bartus RT, Maragakis NJ, Rothstein JD (2007) Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS. Brain Res 1185:256-265
-
(2007)
Brain Res
, vol.1185
, pp. 256-265
-
-
Lepore, A.C.1
Haenggeli, C.2
Gasmi, M.3
Bishop, K.M.4
Bartus, R.T.5
Maragakis, N.J.6
Rothstein, J.D.7
-
40
-
-
54949126674
-
Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease
-
18931666 10.1038/nn.2210 1:CAS:528:DC%2BD1cXht12ltrjN
-
Lepore AC, Rauck B, Dejea C, Pardo AC, Rao MS, Rothstein JD, Maragakis NJ (2008) Focal transplantation-based astrocyte replacement is neuroprotective in a model of motor neuron disease. Nat Neurosci 11:1294-1301
-
(2008)
Nat Neurosci
, vol.11
, pp. 1294-1301
-
-
Lepore, A.C.1
Rauck, B.2
Dejea, C.3
Pardo, A.C.4
Rao, M.S.5
Rothstein, J.D.6
Maragakis, N.J.7
-
41
-
-
77958128995
-
IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells
-
20817874 10.4049/jimmunol.1001536 1:CAS:528:DC%2BC3cXhtFyisrnL
-
Li L, Kim J, Boussiotis VA (2010) IL-1β-mediated signals preferentially drive conversion of regulatory T cells but not conventional T cells into IL-17-producing cells. J Immunol 185:4148-4153
-
(2010)
J Immunol
, vol.185
, pp. 4148-4153
-
-
Li, L.1
Kim, J.2
Boussiotis, V.A.3
-
42
-
-
84863845583
-
Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS
-
22735487 10.1016/j.expneurol.2012.06.011 1:CAS:528:DC%2BC38XhtFGrtLjP
-
Liao B, Zhao W, Beers DR, Henkel JS, Appel SH (2012) Transformation from a neuroprotective to a neurotoxic microglial phenotype in a mouse model of ALS. Exp Neurol 237:147-152
-
(2012)
Exp Neurol
, vol.237
, pp. 147-152
-
-
Liao, B.1
Zhao, W.2
Beers, D.R.3
Henkel, J.S.4
Appel, S.H.5
-
43
-
-
0037096354
-
Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease
-
12077179 1:CAS:528:DC%2BD38Xlt1Sgsrg%3D
-
Lino MM, Schneider C, Caroni P (2002) Accumulation of SOD1 mutants in postnatal motoneurons does not cause motoneuron pathology or motoneuron disease. J Neurosci 22:4825-4832
-
(2002)
J Neurosci
, vol.22
, pp. 4825-4832
-
-
Lino, M.M.1
Schneider, C.2
Caroni, P.3
-
44
-
-
80051782344
-
Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system
-
21684291 10.1016/j.lfs.2011.05.011 1:CAS:528:DC%2BC3MXptVaitLo%3D
-
Liu W, Tang Y, Feng J (2011) Cross talk between activation of microglia and astrocytes in pathological conditions in the central nervous system. Life Sci 89:141-146
-
(2011)
Life Sci
, vol.89
, pp. 141-146
-
-
Liu, W.1
Tang, Y.2
Feng, J.3
-
45
-
-
56549115885
-
Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells
-
19041781 10.1016/j.stem.2008.10.001 1:CAS:528:DC%2BD1cXhsFCqsLjE
-
Marchetto MC, Muotri AR, Mu Y, Smith AM, Cezar GG, Gage FH (2008) Non-cell-autonomous effect of human SOD1 G37R astrocytes on motor neurons derived from human embryonic stem cells. Cell Stem Cell 3:649-657
-
(2008)
Cell Stem Cell
, vol.3
, pp. 649-657
-
-
Marchetto, M.C.1
Muotri, A.R.2
Mu, Y.3
Smith, A.M.4
Cezar, G.G.5
Gage, F.H.6
-
46
-
-
84868623124
-
Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury
-
23041626 10.1172/JCI63113 1:CAS:528:DC%2BC38Xhs1CisL7N
-
Martens LH, Zhang J, Barmada SJ, Zhou P, Kamiya S, Sun B, Min SW, Gan L, Finkbeiner S, Huang EJ, Farese RV Jr (2012) Progranulin deficiency promotes neuroinflammation and neuron loss following toxin-induced injury. J Clin Invest 122:3955-3959
-
(2012)
J Clin Invest
, vol.122
, pp. 3955-3959
-
-
Martens, L.H.1
Zhang, J.2
Barmada, S.J.3
Zhou, P.4
Kamiya, S.5
Sun, B.6
Min, S.W.7
Gan, L.8
Finkbeiner, S.9
Huang, E.J.10
Farese, Jr.R.V.11
-
47
-
-
77955649302
-
Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis
-
20616033 10.1073/pnas.1002396107 1:CAS:528:DC%2BC3cXpsVCrsb0%3D
-
Meissner F, Molawi K, Zychlinsky A (2010) Mutant superoxide dismutase 1-induced IL-1beta accelerates ALS pathogenesis. Proc Natl Acad Sci U S A 107:13046-13050
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 13046-13050
-
-
Meissner, F.1
Molawi, K.2
Zychlinsky, A.3
-
48
-
-
22844452812
-
Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis
-
15990113 10.1016/j.jns.2005.04.011 1:CAS:528:DC%2BD2MXmsVOqsr4%3D
-
Nagano I, Ilieva H, Shiote M, Murakami T, Yokoyama M, Shoji M, Abe K (2005a) Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis. J Neurol Sci 235:61-68
-
(2005)
J Neurol Sci
, vol.235
, pp. 61-68
-
-
Nagano, I.1
Ilieva, H.2
Shiote, M.3
Murakami, T.4
Yokoyama, M.5
Shoji, M.6
Abe, K.7
-
49
-
-
27244455282
-
Beneficial effects of intrathecal IGF-1 administration in patients with amyotrophic lateral sclerosis
-
16197815 10.1179/016164105X39860 1:CAS:528:DC%2BD2MXht1Wkt7fN
-
Nagano I, Shiote M, Murakami T, Kamada H, Hamakawa Y, Matsubara E, Yokoyama M, Moritaz K, Shoji M, Abe K (2005b) Beneficial effects of intrathecal IGF-1 administration in patients with amyotrophic lateral sclerosis. Neurol Res 27:768-772
-
(2005)
Neurol Res
, vol.27
, pp. 768-772
-
-
Nagano, I.1
Shiote, M.2
Murakami, T.3
Kamada, H.4
Hamakawa, Y.5
Matsubara, E.6
Yokoyama, M.7
Moritaz, K.8
Shoji, M.9
Abe, K.10
-
50
-
-
68349146013
-
Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes
-
19280101 10.1007/s00415-009-5097-3 1:CAS:528:DC%2BD1MXpsVegtrY%3D
-
Naor S, Keren Z, Bronshtein T, Goren E, Machluf M, Melamed D (2009) Development of ALS-like disease in SOD-1 mice deficient of B lymphocytes. J Neurol 256:1228-1235
-
(2009)
J Neurol
, vol.256
, pp. 1228-1235
-
-
Naor, S.1
Keren, Z.2
Bronshtein, T.3
Goren, E.4
Machluf, M.5
Melamed, D.6
-
51
-
-
0035149257
-
Control of glial immune function by neurons
-
11596127 10.1002/glia.1108 1:STN:280:DC%2BD3MrkvVyluw%3D%3D
-
Neumann H (2001) Control of glial immune function by neurons. Glia 36:191-199
-
(2001)
Glia
, vol.36
, pp. 191-199
-
-
Neumann, H.1
-
52
-
-
84875153425
-
Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis
-
23396208 10.1038/nm.3085 1:CAS:528:DC%2BC3sXit1ahtb0%3D
-
Nie H, Zheng Y, Li R, Guo TB, He D, Fang L, Liu X, Xiao L, Chen X, Wan B, Chin YE, Zhang JZ (2013) Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis. Nat Med 19:322-328
-
(2013)
Nat Med
, vol.19
, pp. 322-328
-
-
Nie, H.1
Zheng, Y.2
Li, R.3
Guo, T.B.4
He, D.5
Fang, L.6
Liu, X.7
Xiao, L.8
Chen, X.9
Wan, B.10
Chin, Y.E.11
Zhang, J.Z.12
-
53
-
-
33750283275
-
Auto-antibodies against proteins of spinal cord cells in cerebrospinal fluid of patients with amyotrophic lateral sclerosis (ALS)
-
17039414 1:CAS:528:DC%2BD28Xht1WjsLbF
-
Niebroj-Dobosz I, Dziewulska D, Janik P (2006) Auto-antibodies against proteins of spinal cord cells in cerebrospinal fluid of patients with amyotrophic lateral sclerosis (ALS). Folia Neuropathol 44:191-196
-
(2006)
Folia Neuropathol
, vol.44
, pp. 191-196
-
-
Niebroj-Dobosz, I.1
Dziewulska, D.2
Janik, P.3
-
54
-
-
79951704433
-
Neuroinflammation in amyotrophic lateral sclerosis: Role of glial activation in motor neuron disease
-
21349440 10.1016/S1474-4422(11)70015-1 1:CAS:528:DC%2BC3MXit1Wktr8%3D
-
Philips T, Robberecht W (2011) Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease. Lancet Neurol 10:253-263
-
(2011)
Lancet Neurol
, vol.10
, pp. 253-263
-
-
Philips, T.1
Robberecht, W.2
-
55
-
-
78650178041
-
Microglial upregulation of progranulin as a marker of motor neuron degeneration
-
21107132 10.1097/NEN.0b013e3181fc9aea 1:CAS:528:DC%2BC3cXhsV2nsr7J
-
Philips T, De Muynck L, Thu HN, Weynants B, Vanacker P, Dhondt J, Sleegers K, Schelhaas HJ, Verbeek M, Vandenberghe R, Sciot R, Van Broeckhoven C, Lambrechts D, Van Leuven F, Van Den Bosch L, Robberecht W, Van Damme P (2010) Microglial upregulation of progranulin as a marker of motor neuron degeneration. J Neuropathol Exp Neurol 69:1191-1200
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 1191-1200
-
-
Philips, T.1
De Muynck, L.2
Thu, H.N.3
Weynants, B.4
Vanacker, P.5
Dhondt, J.6
Sleegers, K.7
Schelhaas, H.J.8
Verbeek, M.9
Vandenberghe, R.10
Sciot, R.11
Van Broeckhoven, C.12
Lambrechts, D.13
Van Leuven, F.14
Van Den Bosch, L.15
Robberecht, W.16
Van Damme, P.17
-
56
-
-
0035873076
-
Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment
-
11331366 1:CAS:528:DC%2BD3MXjs1antrs%3D
-
Pramatarova A, Laganiere J, Roussel J, Brisebois K, Rouleau GA (2001) Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment. J Neurosci 21:3369-3374
-
(2001)
J Neurosci
, vol.21
, pp. 3369-3374
-
-
Pramatarova, A.1
Laganiere, J.2
Roussel, J.3
Brisebois, K.4
Rouleau, G.A.5
-
57
-
-
80054837386
-
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
-
21944779 10.1016/j.neuron.2011.09.010 1:CAS:528:DC%2BC3MXhtlKrtL%2FI
-
Renton AE, Majounie E, Waite A et al (2011) A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD. Neuron 72:257-268
-
(2011)
Neuron
, vol.72
, pp. 257-268
-
-
Renton, A.E.1
Majounie, E.2
Waite, A.3
-
58
-
-
84858278403
-
Alterations of T cell subsets in ALS: A systemic immune activation?
-
21651502 10.1111/j.1600-0404.2011.01528.x 1:STN:280: DC%2BC383pvVaqtg%3D%3D
-
Rentzos M, Evangelopoulos E, Sereti E, Zouvelou V, Marmara S, Alexakis T, Evdokimidis I (2012) Alterations of T cell subsets in ALS: a systemic immune activation? Acta Neurol Scand 125:260-264
-
(2012)
Acta Neurol Scand
, vol.125
, pp. 260-264
-
-
Rentzos, M.1
Evangelopoulos, E.2
Sereti, E.3
Zouvelou, V.4
Marmara, S.5
Alexakis, T.6
Evdokimidis, I.7
-
59
-
-
84872611309
-
Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype
-
23281114 10.1002/glia.22444
-
Roberts K, Zeineddine R, Corcoran L, Li W, Campbell IL, Yerbury JJ (2013) Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype. Glia 61:409-419
-
(2013)
Glia
, vol.61
, pp. 409-419
-
-
Roberts, K.1
Zeineddine, R.2
Corcoran, L.3
Li, W.4
Campbell, I.L.5
Yerbury, J.J.6
-
60
-
-
49649093608
-
Human anti-inflammatory macrophages induce Foxp3+ GITR + CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1
-
18641362 1:CAS:528:DC%2BD1cXos12ntrc%3D
-
Savage ND, de Boer T, Walburg KV, Joosten SA, van Meijgaarden K, Geluk A, Ottenhoff TH (2008) Human anti-inflammatory macrophages induce Foxp3+ GITR + CD25+ regulatory T cells, which suppress via membrane-bound TGFbeta-1. J Immunol 181:2220-2226
-
(2008)
J Immunol
, vol.181
, pp. 2220-2226
-
-
Savage, N.D.1
De Boer, T.2
Walburg, K.V.3
Joosten, S.A.4
Van Meijgaarden, K.5
Geluk, A.6
Ottenhoff, T.H.7
-
61
-
-
23744445580
-
A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis
-
16082680 10.1002/cne.20620
-
Schaefer AM, Sanes JR, Lichtman JW (2005) A compensatory subpopulation of motor neurons in a mouse model of amyotrophic lateral sclerosis. J Comp Neurol 490:209-219
-
(2005)
J Comp Neurol
, vol.490
, pp. 209-219
-
-
Schaefer, A.M.1
Sanes, J.R.2
Lichtman, J.W.3
-
62
-
-
34247280027
-
CC chemokines and protective immunity: Insights gained from mother-to-child transmission of HIV
-
17304227 10.1038/ni0307-219 1:CAS:528:DC%2BD2sXhslWnu7g%3D
-
Tiemessen CT, Kuhn L (2007) CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV. Nat Immunol 8:219-222
-
(2007)
Nat Immunol
, vol.8
, pp. 219-222
-
-
Tiemessen, C.T.1
Kuhn, L.2
-
63
-
-
1842471942
-
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: An [11C](R)-PK11195 positron emission tomography study
-
10.1016/j.nbd.2003.12.012
-
Turner MR, Cagnin A, Turkheimer FE, Miller CC, Shaw CE, Brooks DJ, Leigh PN, Banati RB (2004) Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiol Dis 5:601-609
-
(2004)
Neurobiol Dis
, vol.5
, pp. 601-609
-
-
Turner, M.R.1
Cagnin, A.2
Turkheimer, F.E.3
Miller, C.C.4
Shaw, C.E.5
Brooks, D.J.6
Leigh, P.N.7
Banati, R.B.8
-
64
-
-
29444443348
-
Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis
-
16369483 10.1038/nn1603 1:CAS:528:DC%2BD2MXhtlCms7rF
-
Urushitani M, Sik A, Sakurai T, Nukina N, Takahashi R, Julien JP (2006) Chromogranin-mediated secretion of mutant superoxide dismutase proteins linked to amyotrophic lateral sclerosis. Nat Neurosci 9:108-118
-
(2006)
Nat Neurosci
, vol.9
, pp. 108-118
-
-
Urushitani, M.1
Sik, A.2
Sakurai, T.3
Nukina, N.4
Takahashi, R.5
Julien, J.P.6
-
65
-
-
84870041158
-
How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: Can we learn from other noncoding repeat expansion disorders?
-
23160421 10.1097/WCO.0b013e32835a3efb
-
Van Blitterswijk M, DeJesus-Hernandez M, Rademakers R (2012) How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: can we learn from other noncoding repeat expansion disorders? Curr Opin Neurol 25:689-700
-
(2012)
Curr Opin Neurol
, vol.25
, pp. 689-700
-
-
Van Blitterswijk, M.1
Dejesus-Hernandez, M.2
Rademakers, R.3
-
66
-
-
67649486844
-
The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis
-
19442735 10.1016/j.nbd.2009.05.002 1:CAS:528:DC%2BD1MXotFCgt7o%3D
-
Wang L, Sharma K, Grisotti G, Roos RP (2009) The effect of mutant SOD1 dismutase activity on non-cell autonomous degeneration in familial amyotrophic lateral sclerosis. Neurobiol Dis 35:234-240
-
(2009)
Neurobiol Dis
, vol.35
, pp. 234-240
-
-
Wang, L.1
Sharma, K.2
Grisotti, G.3
Roos, R.P.4
-
67
-
-
9144230806
-
Increased cytotoxic potential of microglia from ALS-transgenic mice
-
15378658 10.1002/glia.20062
-
Weydt P, Yuen EC, Ransom BR, Moller T (2004) Increased cytotoxic potential of microglia from ALS-transgenic mice. Glia 48:179-182
-
(2004)
Glia
, vol.48
, pp. 179-182
-
-
Weydt, P.1
Yuen, E.C.2
Ransom, B.R.3
Moller, T.4
-
68
-
-
84872363503
-
Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
-
22941226 10.1007/s00401-012-1039-8 1:CAS:528:DC%2BC3sXktVyqsA%3D%3D
-
Winkler EA, Sengillo JD, Sullivan JS, Henkel JS, Appel SH, Zlokovic BV (2013) Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis. Acta Neuropathol 125:111-120
-
(2013)
Acta Neuropathol
, vol.125
, pp. 111-120
-
-
Winkler, E.A.1
Sengillo, J.D.2
Sullivan, J.S.3
Henkel, J.S.4
Appel, S.H.5
Zlokovic, B.V.6
-
69
-
-
34548233140
-
Mutant SOD1G93A microglia are more neurotoxic relative to wild-type microglia
-
17555556 10.1111/j.1471-4159.2007.04677.x 1:CAS:528:DC%2BD2sXhtVyksb7I
-
Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH (2007) Mutant SOD1G93A microglia are more neurotoxic relative to wild-type microglia. J Neurochem 102:2008-2019
-
(2007)
J Neurochem
, vol.102
, pp. 2008-2019
-
-
Xiao, Q.1
Zhao, W.2
Beers, D.R.3
Yen, A.A.4
Xie, W.5
Henkel, J.S.6
Appel, S.H.7
-
70
-
-
39749188753
-
Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis
-
18246065 10.1038/nn2047 1:CAS:528:DC%2BD1cXisFOrurw%3D
-
Yamanaka K, Chun SJ, Boillee S, Fujimori-Tonou N, Yamashita H, Gutmann DH, Takahashi R, Misawa H, Cleveland DW (2008) Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis. Nat Neurosci 11:251-253
-
(2008)
Nat Neurosci
, vol.11
, pp. 251-253
-
-
Yamanaka, K.1
Chun, S.J.2
Boillee, S.3
Fujimori-Tonou, N.4
Yamashita, H.5
Gutmann, D.H.6
Takahashi, R.7
Misawa, H.8
Cleveland, D.W.9
-
71
-
-
4444348187
-
Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism
-
15453095 1:CAS:528:DC%2BD2cXotFajtL4%3D
-
Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH (2004) Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. J Neuropathol Exp Neurol 63:964-977
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 964-977
-
-
Zhao, W.1
Xie, W.2
Le, W.3
Beers, D.R.4
He, Y.5
Henkel, J.S.6
Simpson, E.P.7
Yen, A.A.8
Xiao, Q.9
Appel, S.H.10
-
72
-
-
33750442559
-
Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia
-
17018025 10.1111/j.1471-4159.2006.04172.x 1:CAS:528:DC%2BD28Xht1yks7jM
-
Zhao W, Xie W, Xiao Q, Beers DR, Appel SH (2006) Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. J Neurochem 99:1176-1187
-
(2006)
J Neurochem
, vol.99
, pp. 1176-1187
-
-
Zhao, W.1
Xie, W.2
Xiao, Q.3
Beers, D.R.4
Appel, S.H.5
-
73
-
-
73149105494
-
Extracellular mutant SOD1 induces microglial-mediated motoneuron injury
-
19672969 10.1002/glia.20919
-
Zhao W, Beers DR, Henkel JS, Zhang W, Urushitani M, Julien JP, Appel SH (2010) Extracellular mutant SOD1 induces microglial-mediated motoneuron injury. Glia 58:231-243
-
(2010)
Glia
, vol.58
, pp. 231-243
-
-
Zhao, W.1
Beers, D.R.2
Henkel, J.S.3
Zhang, W.4
Urushitani, M.5
Julien, J.P.6
Appel, S.H.7
-
74
-
-
84864928300
-
Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms
-
22820142 10.1016/j.nbd.2012.07.008 1:CAS:528:DC%2BC38XhsVCjurnP
-
Zhao W, Beers DR, Liao B, Henkel JS, Appel SH (2012) Regulatory T lymphocytes from ALS mice suppress microglia and effector T lymphocytes through different cytokine-mediated mechanisms. Neurobiol Dis 48:418-428
-
(2012)
Neurobiol Dis
, vol.48
, pp. 418-428
-
-
Zhao, W.1
Beers, D.R.2
Liao, B.3
Henkel, J.S.4
Appel, S.H.5
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