Rare variants in neurodegeneration associated genes revealed by targeted panel sequencing in a German ALS cohort

Frontiers in Molecular Neuroscience

Volumn 9, Issue OCT2016, 2016, Pages

  Krüger, Stefanie ^a   Battke, Florian ^a   Sprecher, Andrea ^a   Munz, Marita ^a,b   Synofzik, Matthis ^b,c   Schöls, Ludger ^b,c   Gasser, Thomas ^b,c   Grehl, Torsten ^d   Prudlo, Johannes ^c,e   Biskup, Saskia ^a,b  

^a CEGAT GMBH   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

^e UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Amyotrophic lateral sclerosis; Genetic heterogeneity; Neurodegeneration; Next generation sequencing; Polygenic inheritance

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; COHORT ANALYSIS; DNA EXTRACTION; FAMILIAL INCIDENCE; FEMALE; GENE IDENTIFICATION; GENETIC HETEROGENEITY; GENETIC SCREENING; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GERMANY; HUMAN; HUMAN EXPERIMENT; MAJOR CLINICAL STUDY; MALE; NERVE DEGENERATION; NEXT GENERATION SEQUENCING; PATHOGEN LOAD; POLYMERASE CHAIN REACTION; PROTEIN PROTEIN INTERACTION; YOUNG ADULT;

EID: 84991712819     PISSN: 16625099     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnmol.2016.00092     Document Type: Article

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