Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice

Human Molecular Genetics

Volumn 22, Issue 20, 2013, Pages 4127-4135

  Koval, Erica D ^a   Shaner, Carey ^a   Zhang, Peter ^a   Du Maine, Xavier ^a   Fischer, Kimberlee ^b   Tay, Jia ^b   Nelson Chau, B ^b   Wu, Gregory F ^a   Miller, Timothy M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b REGULUS THERAPEUTICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COPPER ZINC SUPEROXIDE DISMUTASE; MICRORNA; MICRORNA 106A; MICRORNA 142 5P; MICRORNA 146A; MICRORNA 146B; MICRORNA 155; MICRORNA 155 ANTISENSE OLIGONUCLEOTIDE; MICRORNA 17; MICRORNA 19B; MICRORNA 20A; MICRORNA 223; MICRORNA 24; UNCLASSIFIED DRUG;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BINDING SITE; CONTROLLED STUDY; DISEASE DURATION; FEMALE; HUMAN; HUMAN TISSUE; LUMBAR SPINAL CORD; MALE; MOUSE; NONHUMAN; OSMOTIC PUMP; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SURVIVAL; SURVIVAL TIME;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BRAIN; CASE-CONTROL STUDIES; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICRORNAS; MIDDLE AGED; MOLECULAR TARGETED THERAPY; OLIGONUCLEOTIDES, ANTISENSE; RATS; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84884712642     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt261     Document Type: Article

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