Intricate interplay between astrocytes and motor neurons in ALS

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 8, 2013, Pages

  Phatnani, Hemali P ^a   Guarnieri, Paolo ^a   Friedman, Brad A ^b,d   Carrasco, Monica A ^a   Muratet, Michael ^c   O'Keeffe, Sean ^a   Nwakeze, Chiamaka ^a   Pauli Behn, Florencia ^c   Newberry, Kimberly M ^c   Meadows, Sarah K ^c   Tapia, Juan Carlos ^a   Myers, Richard M ^c   Maniatis, Tom ^a  

^a New York Presbyterian Morgan Stanley Children's Hospital   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HUDSONALPHA INSTITUTE FOR BIOTECHNOLOGY   (United States)

^d GENENTECH INC   (United States)

Author keywords

Cell intrinsic and extrinsic effects on gene expression; G93A mouse model of ALS; Motor neuron gene expression in ALS; Reactive astrocyte gene expression in ALS

Indexed keywords

SUPEROXIDE DISMUTASE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2;

ALLELE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL MODEL; ARTICLE; ASTROCYTE; ASTROCYTOSIS; BIOINFORMATICS; CELL FUNCTION; CELL INTERACTION; CELL ISOLATION; CELL SPECIFICITY; COCULTURE; CONTROLLED STUDY; DISEASE COURSE; EMBRYONIC STEM CELL; GENE EXPRESSION; GLIA CELL; HUMAN; IMMUNOREACTIVITY; MICROGLIA; MOTONEURON; MOUSE; MUTANT; NERVE CELL DIFFERENTIATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RNA SEQUENCE; SIGNAL TRANSDUCTION; SPINAL CORD; TISSUE INJURY; UPREGULATION; WILD TYPE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; HUMANS; MICE; MOTOR NEURONS; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SPINAL CORD; SUPEROXIDE DISMUTASE; UP-REGULATION;

EID: 84874255781     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1222361110     Document Type: Article

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