Body fluid exosomes promote secretion of inflammatory cytokines in monocytic cells via Toll-Like receptor signaling

Journal of Biological Chemistry

Volumn 288, Issue 51, 2013, Pages 36691-36702

  Bretz, Niko P ^a   Ridinger, Johannes ^a   Rupp, Anne Kathleen ^a   Rimbach, Katharina ^b   Keller, Sascha ^a   Rupp, Christian ^b   Marmé, Frederik ^b   Umansky, Ludmila ^a   Umansky, Viktor ^b   Eigenbrod, Tatjana ^b   Sammar, Marei ^c   Altevogt, Peter ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c ORT BRAUDE COLLEGE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CANCER PROGRESSION; DELAYED ACTIVATION; IMMUNOMODULATORY EFFECTS; INFLAMMATORY CYTOKINES; INFLAMMATORY DISEASE; SIGNALING PATHWAYS; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTORS;

ACTIVATION ANALYSIS; ANTIBODIES; BODY FLUIDS; CELLS; CYTOLOGY; DISEASES; IMMUNOLOGY; SIGNALING; TUMORS;

CELL SIGNALING;

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; NEUTRALIZING ANTIBODY; STAT3 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

AMNION FLUID; ANIMAL CELL; ARTICLE; ASCITES FLUID; AUTOCRINE EFFECT; BODY FLUID; CELL ACTIVATION; CELL ACTIVITY; CELL DIFFERENTIATION; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; EX VIVO STUDY; EXOSOME; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MACROPHAGE; MALIGNANT ASCITES; MONOCYTE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN FUNCTION;

AMNIOTIC FLUID; CYTOKINE INDUCTION; EXOSOMES; MALIGNANT ASCITES; NFΚB TRANSCRIPTION FACTOR; STAT3; TOLL-LIKE RECEPTOR (TLR);

AMNIOTIC FLUID; ANIMALS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CYTOKINES; DENDRITIC CELLS; EXOSOMES; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MICE; MICE, INBRED C57BL; MONOCYTE-MACROPHAGE PRECURSOR CELLS; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890904610     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.512806     Document Type: Article

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