Interactions between exosomes from breast cancer cells and primary mammary epithelial cells leads to generation of reactive oxygen species which induce DNA damage response, stabilization of p53 and autophagy in epithelial cells

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Dutta, Sujoy ^a   Warshall, Case ^a   Bandyopadhyay, Chirosree ^a   Dutta, Dipanjan ^a   Chandran, Bala ^a  

^a ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ATM PROTEIN; CHECKPOINT KINASE 1; DNA FRAGMENT; HISTONE H2AX; MESSENGER RNA; MICRORNA; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SERINE; SERINE 15; SODIUM; UNCLASSIFIED DRUG; CULTURE MEDIUM; DNA; TP53 PROTEIN, HUMAN;

ARTICLE; AUTOPHAGY; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL; CANCER GROWTH; CARCINOGENESIS; CELL COMMUNICATION; CELL INTERACTION; CELL TYPE; DNA DAMAGE; DNA FRAGMENTATION; DNA REPAIR; EPITHELIUM CELL; EXOSOME; HUMAN; MCF 7 CELL LINE; METASTASIS; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY; RECIPIENT; TUMOR MICROENVIRONMENT; BREAST; BREAST TUMOR; CHEMISTRY; CULTURE MEDIUM; CYTOLOGY; FEMALE; METABOLISM; PATHOLOGY; PHOSPHORYLATION; TUMOR CELL LINE;

ACETYLCYSTEINE; AUTOPHAGY; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CULTURE MEDIA, CONDITIONED; DNA; DNA DAMAGE; DNA REPAIR; EPITHELIAL CELLS; EXOSOMES; FEMALE; HUMANS; MCF-7 CELLS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901366761     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097580     Document Type: Article

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