Microglia change from a reactive to an age-like phenotype with the time in culture

Frontiers in Cellular Neuroscience

Volumn 8, Issue JUN, 2014, Pages

  Caldeira, Cláudia ^a,b   Oliveira, Ana F ^a   Cunha, Carolina ^a   Vaz, Ana R ^a,c   Falcão, Ana S ^a,c   Fernandes, Adelaide ^a,c   Brites, Dora ^a,c  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b INSTITUTO SUPERIOR DE CIÊNCIAS DA SAÚDE EGAS MONIZ   (Portugal)

^c UNIVERSITY OF LISBON   (Portugal)

Author keywords

Autophagic capacity; In vitro cell aging; Microglia; MicroRNAs; Migration; Phagocytosis; Reactivity; Senescence

Indexed keywords

BETA GALACTOSIDASE; GELATINASE B; GLUTAMIC ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; MICRORNA 124; MICRORNA 146A; MICRORNA 155; SENESCENCE ASSOCIATED BETA GALACTOSIDASE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBODY LABELING; ARTICLE; ASTROCYTE; AUTOPHAGY; AUTORADIOGRAPHY; CELL AGING; CELL DEATH; CELL MIGRATION; CELL MIGRATION ASSAY; CELL STRUCTURE; CONTROLLED STUDY; FLOW CYTOMETRY; GEL ELECTROPHORESIS; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOFLUORESCENCE TEST; MICROGLIA; MORPHOLOGY; MOUSE; NERVE DEGENERATION; NERVE POTENTIAL; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PHENOTYPE; PROTEIN DETERMINATION; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; SPECTROPHOTOMETRY;

EID: 84901848126     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2014.00152     Document Type: Article

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