TREM2 in CNS homeostasis and neurodegenerative disease

Molecular Neurodegeneration

Volumn 10, Issue 1, 2015, Pages

  Painter, Meghan M ^a   Atagi, Yuka ^a   Liu, Chia Chen ^a,b   Rademakers, Rosa ^a   Xu, Huaxi ^b   Fryer, John D ^a,c   Bu, Guojun ^a,b,c  

^a MAYO GRADUATE SCHOOL   (United States)

^b XIAMEN UNIVERSITY   (China)

^c MAYO CLINIC   (United States)

Author keywords

Alzheimer's disease; Inflammation; Microglia; TREM2

Indexed keywords

KILLER CELL ACTIVATING RECEPTOR ASSOCIATED PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; CYTOKINE; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; NERVE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TOLL LIKE RECEPTOR; TREM2 PROTEIN, HUMAN; TYROBP PROTEIN, HUMAN;

ALZHEIMER DISEASE; BONE MARROW CELL; CELL PROLIFERATION; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CYTOKINE PRODUCTION; DEGENERATIVE DISEASE; GENE MUTATION; HOMEOSTASIS; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MICROGLIA; MOLECULAR INTERACTION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PATHOGENESIS; PHAGOCYTOSIS; PHENOTYPE; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; TREM2 GENE; ANIMAL; BIOLOGICAL MODEL; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; MOUSE; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; REGENERATION; WOUND HEALING;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ALZHEIMER DISEASE; ANIMALS; CENTRAL NERVOUS SYSTEM; CYTOKINES; HOMEOSTASIS; HUMANS; IMMUNITY, INNATE; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICROGLIA; MODELS, BIOLOGICAL; MUTATION; MYELOID CELLS; NERVE TISSUE PROTEINS; NEURODEGENERATIVE DISEASES; RECEPTORS, IMMUNOLOGIC; REGENERATION; TOLL-LIKE RECEPTORS; WOUND HEALING;

EID: 84940731281     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-015-0040-9     Document Type: Review

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