Integrated microRNA, mRNA, and protein expression profiling reveals microRNA regulatory networks in rat kidney treated with a carcinogenic dose of aristolochic acid

BMC Genomics

Volumn 16, Issue 1, 2015, Pages

  Li, Zhiguang ^a   Qin, Taichun ^b   Wang, Kejian ^b   Hackenberg, Michael ^c   Yan, Jian ^b   Gao, Yuan ^b   Yu, Li Rong ^b   Shi, Leming ^b,d   Su, Zhenqiang ^b   Chen, Tao ^b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^c UNIVERSITY OF GRANADA   (Spain)

^d FUDAN UNIVERSITY   (China)

Author keywords

Aristolochic acid; Carcinogenesis; Deep Sequencing; Kidney tumor; microRNA; Proteomics; Rat; RNA array; Target prediction

Indexed keywords

ARISTOLOCHIC ACID; MESSENGER RNA; MICRORNA; ARISTOLOCHIC ACID I; CARCINOGEN; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CLUSTER ANALYSIS; CONTROLLED STUDY; GENE ACTIVATION; GENE REGULATORY NETWORK; GENE REPRESSION; GENE TARGETING; KIDNEY TUMOR; MALE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; RAT; REAL TIME POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; KIDNEY; KIDNEY NEOPLASMS; METABOLISM; MOLECULAR GENETICS;

ARISTOLOCHIA; RATTUS;

ANIMALS; ARISTOLOCHIC ACIDS; CARCINOGENS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE REGULATORY NETWORKS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; KIDNEY; KIDNEY NEOPLASMS; MALE; MICRORNAS; MOLECULAR SEQUENCE DATA; PROTEOMICS; RATS; RNA, MESSENGER; RNA, NEOPLASM; SEQUENCE ANALYSIS, RNA;

EID: 84930647574     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/s12864-015-1516-2     Document Type: Article

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