-
1
-
-
83955163721
-
Designing biological systems: Systems engineering meets synthetic biology
-
Rollie, S., Mangold, M., and Sundmacher, K. (2012) Designing biological systems: Systems Engineering meets Synthetic Biology. Chem. Eng. Sci. 69, 1-29.
-
(2012)
Chem. Eng. Sci.
, vol.69
, pp. 1-29
-
-
Rollie, S.1
Mangold, M.2
Sundmacher, K.3
-
2
-
-
79952079989
-
Synthetic toxicology: Where engineering meets biology and toxicology
-
Schmidt, M., and Pei, L. (2011) Synthetic toxicology: Where engineering meets biology and toxicology. Toxicol. Sci. 120, S204-S224.
-
(2011)
Toxicol. Sci.
, vol.120
, pp. S204-S224
-
-
Schmidt, M.1
Pei, L.2
-
3
-
-
0024354143
-
Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in saccharomyces cerevisiae
-
Brian, W. R., and Srivastava, P. K., Umbenhauer, D. R., Lloyd, R. S., and Guengerich, F. P. (1989) Expression of a human liver cytochrome P-450 protein with tolbutamide hydroxylase activity in Saccharomyces cerevisiae. Biochemistry 28, 4993-4999.
-
(1989)
Biochemistry
, vol.28
, pp. 4993-4999
-
-
Brian, W.R.1
Srivastava, P.K.2
Umbenhauer, D.R.3
Lloyd, R.S.4
Guengerich, F.P.5
-
4
-
-
0025161416
-
Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3)
-
Wrighton, S. A., and Brian, W. R., Sari, M. A., Iwasaki, M., Guengerich, F. P., and Raucy, J. L., Molowa, D. T., and VandenBranden, M. (1990) Studies on the expression and metabolic capabilities of human liver cytochrome P450IIIA5 (HLp3). Mol. Pharmacol. 38, 207-213.
-
(1990)
Mol. Pharmacol.
, vol.38
, pp. 207-213
-
-
Wrighton, S.A.1
Brian, W.R.2
Sari, M.A.3
Iwasaki, M.4
Guengerich, F.P.5
Raucy, J.L.6
Molowa, D.T.7
VandenBranden, M.8
-
5
-
-
0025670512
-
Expression of human liver cytochrome P450 IIIA4 in yeast: A functional model for the hepatic enzyme
-
Renaud, J.-P., Cullin, C., Pompon, D., Beaune, P., and Mansuy, D. (1990) Expression of human liver cytochrome P450 IIIA4 in yeast: a functional model for the hepatic enzyme. Eur. J. Biochem. 194, 889-896.
-
(1990)
Eur. J. Biochem.
, vol.194
, pp. 889-896
-
-
Renaud, J.-P.1
Cullin, C.2
Pompon, D.3
Beaune, P.4
Mansuy, D.5
-
6
-
-
0026336750
-
Expression of Mammalian cytochrome P450 enzymes using yeast-based vectors
-
Guengerich, F. P., and Brian, W. R., Sari, M.-A., and Ross, J. T. (1991) Expression of mammalian cytochrome P450 enzymes using yeast-based vectors. Methods Enzymol. 206, 130-145.
-
(1991)
Methods Enzymol.
, vol.206
, pp. 130-145
-
-
Guengerich, F.P.1
Brian, W.R.2
Sari, M.-A.3
Ross, J.T.4
-
7
-
-
0025819695
-
Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli
-
Larson, J. R., and Coon, M. J., and Porter, T. D. (1991) Alcohol-inducible cytochrome P-450IIE1 lacking the hydrophobic NH2-terminal segment retains catalytic activity and is membrane-bound when expressed in Escherichia coli. J. Biol. Chem. 266, 7321-7324.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 7321-7324
-
-
Larson, J.R.1
Coon, M.J.2
Porter, T.D.3
-
8
-
-
0026601890
-
High level expression of functional human cytochrome P450 1A2 in Escherichia coli
-
Fisher, C. W., and Caudle, D. L., Martinwixtrom, C., Quattrochi, L. C., and Tukey, R. H., Waterman, M. R., and Estabrook, R. W. (1992) High level expression of functional human cytochrome P450 1A2 in Escherichia coli. FASEB J. 6, 759-764.
-
(1992)
FASEB J.
, vol.6
, pp. 759-764
-
-
Fisher, C.W.1
Caudle, D.L.2
Martinwixtrom, C.3
Quattrochi, L.C.4
Tukey, R.H.5
Waterman, M.R.6
Estabrook, R.W.7
-
9
-
-
0026679782
-
Expression of a catalytically active human cytochrome P-450 2E1 in Escherichia coli
-
Winters, D. K., and Cederbaum, A. I. (1992) Expression of a catalytically active human cytochrome P-450 2E1 in Escherichia coli. Biochim. Biophys. Acta, Gen. Subj. 1156, 43-49.
-
(1992)
Biochim. Biophys. Acta, Gen. Subj.
, vol.1156
, pp. 43-49
-
-
Winters, D.K.1
Cederbaum, A.I.2
-
10
-
-
0027223881
-
Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme
-
Gillam, E. M. J., Baba, T., Kim, B.-R., Ohmori, S., and Guengerich, F. P. (1993) Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme. Arch. Biochem. Biophys. 305, 123-131.
-
(1993)
Arch. Biochem. Biophys.
, vol.305
, pp. 123-131
-
-
Gillam, E.M.J.1
Baba, T.2
Kim, B.-R.3
Ohmori, S.4
Guengerich, F.P.5
-
11
-
-
0027497950
-
Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: Influence of NH2-terminal region on localization in cytosol and membranes
-
Pernecky, S. J., and Larson, J. R., Philpot, R. M., and Coon, M. J. (1993) Expression of truncated forms of liver microsomal P450 cytochromes 2B4 and 2E1 in Escherichia coli: influence of NH2-terminal region on localization in cytosol and membranes. Proc. Natl. Acad. Sci. U. S. A. 90, 2651-2655.
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 2651-2655
-
-
Pernecky, S.J.1
Larson, J.R.2
Philpot, R.M.3
Coon, M.J.4
-
12
-
-
0027420580
-
Expression of modified cytochrome P450 2C10 (2C9) in Escherichia coli, purification, and reconstitution of catalytic activity
-
Sandhu, P., Baba, T., and Guengerich, F. P. (1993) Expression of modified cytochrome P450 2C10 (2C9) in Escherichia coli, purification, and reconstitution of catalytic activity. Arch. Biochem. Biophys. 306, 443-450.
-
(1993)
Arch. Biochem. Biophys.
, vol.306
, pp. 443-450
-
-
Sandhu, P.1
Baba, T.2
Guengerich, F.P.3
-
13
-
-
0028023169
-
Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties
-
Gillam, E. M. J., Guo, Z., and Guengerich, F. P. (1994) Expression of modified human cytochrome P450 2E1 in Escherichia coli, purification, and spectral and catalytic properties. Arch. Biochem. Biophys. 312, 59-66.
-
(1994)
Arch. Biochem. Biophys.
, vol.312
, pp. 59-66
-
-
Gillam, E.M.J.1
Guo, Z.2
Guengerich, F.P.3
-
14
-
-
0028071497
-
Expression of modified human cytochrome P450 1A1 in Escherichia coli: Effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties
-
Guo, Z., Gillam, E. M. J., Ohmori, S., Tukey, R. H., and Guengerich, F. P. (1994) Expression of modified human cytochrome P450 1A1 in Escherichia coli: effects of 5' substitution, stabilization, purification, spectral characterization, and catalytic properties. Arch. Biochem. Biophys. 312, 436-446.
-
(1994)
Arch. Biochem. Biophys.
, vol.312
, pp. 436-446
-
-
Guo, Z.1
Gillam, E.M.J.2
Ohmori, S.3
Tukey, R.H.4
Guengerich, F.P.5
-
15
-
-
0028977906
-
Expression of cytochrome P450 2D6 in Escherichia coli: Purification, and spectral and catalytic characterization
-
Gillam, E. M. J., and Guo, Z. Y., Martin, M. V., Jenkins, C. M., and Guengerich, F. P. (1995) Expression of cytochrome P450 2D6 in Escherichia coli: Purification, and spectral and catalytic characterization. Arch. Biochem. Biophys. 319, 540-550.
-
(1995)
Arch. Biochem. Biophys.
, vol.319
, pp. 540-550
-
-
Gillam, E.M.J.1
Guo, Z.Y.2
Martin, M.V.3
Jenkins, C.M.4
Guengerich, F.P.5
-
16
-
-
0029128324
-
Truncated human P450 2D6: Expression in Escherichia coli: Ni2+-chelate affinity purification, and characterization of solubility and aggregation
-
Kempf, A., and Zanger, U. M., and Meyer, U. A. (1995) Truncated human P450 2D6: expression in Escherichia coli: Ni2+-chelate affinity purification, and characterization of solubility and aggregation. Arch. Biochem. Biophys. 321, 277-288.
-
(1995)
Arch. Biochem. Biophys.
, vol.321
, pp. 277-288
-
-
Kempf, A.1
Zanger, U.M.2
Meyer, U.A.3
-
17
-
-
0031572185
-
A general strategy for the expression of recombinant human cytochrome P450s in Escherichia coli using bacterial signal peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
-
Pritchard, M. P., Ossetian, R., Li, D. N., and Henderson, C. J., Burchell, B., Wolf, C. R., and Friedberg, T. (1997) A general strategy for the expression of recombinant human cytochrome P450s in Escherichia coli using bacterial signal peptides: Expression of CYP3A4, CYP2A6, and CYP2E1. Arch. Biochem. Biophys. 345, 342-354.
-
(1997)
Arch. Biochem. Biophys.
, vol.345
, pp. 342-354
-
-
Pritchard, M.P.1
Ossetian, R.2
Li, D.N.3
Henderson, C.J.4
Burchell, B.5
Wolf, C.R.6
Friedberg, T.7
-
18
-
-
0026773549
-
Optimization of yeast-expressed human liver cytochrome-P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5
-
Peyronneau, M. A., and Renaud, J. P., Truan, G., Urban, P., Pompon, D., and Mansuy, D. (1992) Optimization of yeast-expressed human liver cytochrome-P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5. Eur. J. Biochem. 207, 109-116.
-
(1992)
Eur. J. Biochem.
, vol.207
, pp. 109-116
-
-
Peyronneau, M.A.1
Renaud, J.P.2
Truan, G.3
Urban, P.4
Pompon, D.5
Mansuy, D.6
-
19
-
-
0030843652
-
Drug metabolism by Escherichia coli expressing human cytochromes P450
-
Parikh, A., Gillam, E. M. J., and Guengerich, F. P. (1997) Drug metabolism by Escherichia coli expressing human cytochromes P450. Nat. Biotechnol. 15, 784-788.
-
(1997)
Nat. Biotechnol.
, vol.15
, pp. 784-788
-
-
Parikh, A.1
Gillam, E.M.J.2
Guengerich, F.P.3
-
20
-
-
33750094959
-
Simultaneous expression of human P450 and human NADPH-P450 reductase in E-coli: Extremely high activity to metabolize drugs
-
Fujita, K., Iwata, H., Kushida, H., Suzuki, A., Nakamura, K., Konno, Y., and Kamataki, T. (1997) Simultaneous expression of human P450 and human NADPH-P450 reductase in E-coli: Extremely high activity to metabolize drugs. FASEB J. 11, A791-A791.
-
(1997)
FASEB J.
, vol.11
, pp. A791-A791
-
-
Fujita, K.1
Iwata, H.2
Kushida, H.3
Suzuki, A.4
Nakamura, K.5
Konno, Y.6
Kamataki, T.7
-
21
-
-
0030592712
-
Coexpression of a human P450 (CYP3A4) and P450 reductase generated a highly functional monooxygenase system in Escherichia coli
-
Blake, J. A. R., Pritchard, M., Ding, S., Smith, G. C. M., Burchell, B., Wolf, C. R., and Friedberg, T. (1996) Coexpression of a human P450 (CYP3A4) and P450 reductase generated a highly functional monooxygenase system in Escherichia coli. FEBS Lett. 397, 210-214.
-
(1996)
FEBS Lett.
, vol.397
, pp. 210-214
-
-
Blake, J.A.R.1
Pritchard, M.2
Ding, S.3
Smith, G.C.M.4
Burchell, B.5
Wolf, C.R.6
Friedberg, T.7
-
22
-
-
0030725269
-
Heterologous expression of human drug-metabolizing enzymes
-
Guengerich, F. P., Parikh, A., Johnson, E. F., and Richardson, T. H., VonWachenfeldt, C., Cosme, J., Jung, F., and Strassburg, C. P., Manns, M. P., Tukey, R. H., Pritchard, M., Fournel Gigleux, S., and Burchell, B. (1997) Heterologous expression of human drug-metabolizing enzymes. Drug Metab. Dispos. 25, 1234-1241.
-
(1997)
Drug Metab. Dispos.
, vol.25
, pp. 1234-1241
-
-
Guengerich, F.P.1
Parikh, A.2
Johnson, E.F.3
Richardson, T.H.4
VonWachenfeldt, C.5
Cosme, J.6
Jung, F.7
Strassburg, C.P.8
Manns, M.P.9
Tukey, R.H.10
Pritchard, M.11
Fournel Gigleux, S.12
Burchell, B.13
-
23
-
-
33646494635
-
Functional expression of human cytochrome P450 enzymes in Escherichia coli
-
Yun, C. H., and Yim, S. K., Kim, D. H., and Ahn, T. (2006) Functional expression of human cytochrome P450 enzymes in Escherichia coli. Curr. Drug Metab. 7, 411-429.
-
(2006)
Curr. Drug Metab.
, vol.7
, pp. 411-429
-
-
Yun, C.H.1
Yim, S.K.2
Kim, D.H.3
Ahn, T.4
-
24
-
-
0031797278
-
Human cytochrome P450 enzymes expressed in bacteria: Reagents to probe molecular interactions in toxicology
-
Gillam, E. M. J. (1998) Human cytochrome P450 enzymes expressed in bacteria: Reagents to probe molecular interactions in toxicology. Clin. Exp. Pharmacol. Physiol. 25, 877-886.
-
(1998)
Clin. Exp. Pharmacol. Physiol.
, vol.25
, pp. 877-886
-
-
Gillam, E.M.J.1
-
25
-
-
0034044068
-
Bioreactor systems in drug metabolism: Synthesis of cytochrome P450-generated metabolites
-
Rushmore, T. H., and Reider, P. J., Slaughter, D., Assang, C., and Shou, M. (2000) Bioreactor systems in drug metabolism: Synthesis of cytochrome P450-generated metabolites. Metab. Eng. 2, 115-125.
-
(2000)
Metab. Eng.
, vol.2
, pp. 115-125
-
-
Rushmore, T.H.1
Reider, P.J.2
Slaughter, D.3
Assang, C.4
Shou, M.5
-
26
-
-
17644376530
-
Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli
-
Vail, R. B., and Homann, M. J., Hanna, I., and Zaks, A. (2005) Preparative synthesis of drug metabolites using human cytochrome P450s 3A4, 2C9 and 1A2 with NADPH-P450 reductase expressed in Escherichia coli. J. Ind. Microbiol. Biotechnol. 32, 67-74.
-
(2005)
J. Ind. Microbiol. Biotechnol.
, vol.32
, pp. 67-74
-
-
Vail, R.B.1
Homann, M.J.2
Hanna, I.3
Zaks, A.4
-
27
-
-
80555150588
-
Facile production of minor metabolites for drug development using a CYP3A shuffled library
-
Hunter, D. J. B., Behrendorff, J. B. Y. H., Johnston, W. A., Hayes, P. Y., Huang, W., Bonn, B., Hayes, M. A., De Voss, J. J., and Gillam, E. M. J. (2011) Facile production of minor metabolites for drug development using a CYP3A shuffled library. Metab. Eng. 13, 682-693.
-
(2011)
Metab. Eng.
, vol.13
, pp. 682-693
-
-
Hunter, D.J.B.1
Behrendorff, J.B.Y.H.2
Johnston, W.A.3
Hayes, P.Y.4
Huang, W.5
Bonn, B.6
Hayes, M.A.7
De Voss, J.J.8
Gillam, E.M.J.9
-
28
-
-
0036558027
-
P450BM3: The very model of a modern flavocytochrome
-
Munro, A. W., and Leys, D. G., McLean, K. J., Marshall, K. R., Ost, T. W. B., Daff, S., Miles, C. S., and Chapman, S. K., Lysek, D. A., Moser, C. C., Page, C. C., and Dutton, P. L. (2002) P450BM3: the very model of a modern flavocytochrome. Trends Biochem. Sci. 27, 250-257.
-
(2002)
Trends Biochem. Sci.
, vol.27
, pp. 250-257
-
-
Munro, A.W.1
Leys, D.G.2
McLean, K.J.3
Marshall, K.R.4
Ost, T.W.B.5
Daff, S.6
Miles, C.S.7
Chapman, S.K.8
Lysek, D.A.9
Moser, C.C.10
Page, C.C.11
Dutton, P.L.12
-
29
-
-
33646753362
-
Structure-guided recombination creates an artificial family of cytochromes P450
-
Otey, C. R., Landwehr, M., Endelman, J. B., Hiraga, K., and Bloom, J. D., and Arnold, F. H. (2006) Structure-guided recombination creates an artificial family of cytochromes P450. PLoS Biol. 4, e112.
-
(2006)
PLoS Biol.
, vol.4
, pp. e112
-
-
Otey, C.R.1
Landwehr, M.2
Endelman, J.B.3
Hiraga, K.4
Bloom, J.D.5
Arnold, F.H.6
-
30
-
-
70350518093
-
A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds
-
Sawayama, A. M., Chen, M. M. Y., Kulanthaivel, P., Kuo, M. S., Hemmerle, H., and Arnold, F. H. (2009) A panel of cytochrome P450 BM3 variants to produce drug metabolites and diversify lead compounds. Chem. - Eur. J. 15, 11723-11729.
-
(2009)
Chem. - Eur. J.
, vol.15
, pp. 11723-11729
-
-
Sawayama, A.M.1
Chen, M.M.Y.2
Kulanthaivel, P.3
Kuo, M.S.4
Hemmerle, H.5
Arnold, F.H.6
-
31
-
-
36549051541
-
Application of drug metabolising mutants of cytochrome P450BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites
-
Damsten, M. C., van Vugt-Lussenburg, B. M. A., Zeldenthuis, T., de Vlieger, J. S. B., Commandeur, J. N. M., and Vermeulen, N. P. E. (2008) Application of drug metabolising mutants of cytochrome P450BM3 (CYP102A1) as biocatalysts for the generation of reactive metabolites. Chem.-Biol. Interact. 171, 96-107.
-
(2008)
Chem.-Biol. Interact.
, vol.171
, pp. 96-107
-
-
Damsten, M.C.1
Van Vugt-Lussenburg, B.M.A.2
Zeldenthuis, T.3
De Vlieger, J.S.B.4
Commandeur, J.N.M.5
Vermeulen, N.P.E.6
-
32
-
-
80051761925
-
Application of CYP102A1M11H as a tool for the generation of protein adducts of reactive drug metabolites
-
Boerma, J. S., Vermeulen, N. P. E., and Commandeur, J. N. M. (2011) Application of CYP102A1M11H as a tool for the generation of protein adducts of reactive drug metabolites. Chem. Res. Toxicol. 24, 1263-1274.
-
(2011)
Chem. Res. Toxicol.
, vol.24
, pp. 1263-1274
-
-
Boerma, J.S.1
Vermeulen, N.P.E.2
Commandeur, J.N.M.3
-
33
-
-
33846931755
-
Identification of critical residues in novel drug metabolizing mutants of cytochrome P450 BM3 using random mutagenesis
-
van Vugt-Lussenburg, B. M. A., Stjernschantz, E., Lastdrager, J., Oostenbrink, C., Vermeulen, N. P. E., and Commandeur, J. N. M. (2007) Identification of critical residues in novel drug metabolizing mutants of cytochrome P450 BM3 using random mutagenesis. J. Med. Chem. 50, 455-461.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 455-461
-
-
Van Vugt-Lussenburg, B.M.A.1
Stjernschantz, E.2
Lastdrager, J.3
Oostenbrink, C.4
Vermeulen, N.P.E.5
Commandeur, J.N.M.6
-
34
-
-
77949540506
-
Oxidation of human cytochrome P450 1A2 substrates by bacillus megaterium cytochrome P450 BM3
-
Kim, D. H., and Kim, K. H., Kim, D., Jung, H. C., and Pan, J. G., Chi, Y. T., Ahn, T., and Yun, C. H. (2010) Oxidation of human cytochrome P450 1A2 substrates by Bacillus megaterium cytochrome P450 BM3. J. Mol. Catal. B: Enzym. 63, 179-187.
-
(2010)
J. Mol. Catal. B: Enzym.
, vol.63
, pp. 179-187
-
-
Kim, D.H.1
Kim, K.H.2
Kim, D.3
Jung, H.C.4
Pan, J.G.5
Chi, Y.T.6
Ahn, T.7
Yun, C.H.8
-
35
-
-
76749092561
-
Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation
-
Kumar, S. (2010) Engineering cytochrome P450 biocatalysts for biotechnology, medicine and bioremediation. Expert Opin. Drug Metab. Toxicol. 6, 115-131.
-
(2010)
Expert Opin. Drug Metab. Toxicol.
, vol.6
, pp. 115-131
-
-
Kumar, S.1
-
36
-
-
84887948410
-
The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development
-
Gillam, E. M. J., and Hayes, M. A. (2013) The evolution of cytochrome P450 enzymes as biocatalysts in drug discovery and development. Curr. Top. Med. Chem. 13, 2254-2280.
-
(2013)
Curr. Top. Med. Chem.
, vol.13
, pp. 2254-2280
-
-
Gillam, E.M.J.1
Hayes, M.A.2
-
37
-
-
79952268861
-
Cytochromes P450 as useful biocatalysts: Addressing the limitations
-
O'Reilly, E., Kohler, V., and Flitsch, S. L., and Turner, N. J. (2011) Cytochromes P450 as useful biocatalysts: addressing the limitations. Chem. Commun. 47, 2490-2501.
-
(2011)
Chem. Commun.
, vol.47
, pp. 2490-2501
-
-
O'Reilly, E.1
Kohler, V.2
Flitsch, S.L.3
Turner, N.J.4
-
38
-
-
33846356640
-
Cytochrome P450-redox partner fusion enzymes
-
Munro, A. W., and Girvan, H. M., and McLean, K. J. (2007) Cytochrome P450-redox partner fusion enzymes. Biochim. Biophys. Acta, Gen. Subj. 1770, 345-359.
-
(2007)
Biochim. Biophys. Acta, Gen. Subj.
, vol.1770
, pp. 345-359
-
-
Munro, A.W.1
Girvan, H.M.2
McLean, K.J.3
-
39
-
-
0030057886
-
Probing electron transfer in flavocytochrome P-450 BM3 and its component domains
-
Munro, A. W., Daff, S., Coggins, J. R., and Lindsay, J. G., and Chapman, S. K. (1996) Probing electron transfer in flavocytochrome P-450 BM3 and its component domains. Eur. J. Biochem. 239, 403-409.
-
(1996)
Eur. J. Biochem.
, vol.239
, pp. 403-409
-
-
Munro, A.W.1
Daff, S.2
Coggins, J.R.3
Lindsay, J.G.4
Chapman, S.K.5
-
40
-
-
0026485793
-
High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of cytochromes P450 and NADPH-P450 reductase flavoprotein
-
Fisher, C. W., and Shet, M. S., Martin-Wixtrom, C., and Estabrook, R. W. (1992) High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of cytochromes P450 and NADPH-P450 reductase flavoprotein. Proc. Natl. Acad. Sci. U. S. A. 89, 10817-10821.
-
(1992)
Proc. Natl. Acad. Sci. U.S.A.
, vol.89
, pp. 10817-10821
-
-
Fisher, C.W.1
Shet, M.S.2
Martin-Wixtrom, C.3
Estabrook, R.W.4
-
41
-
-
0028291187
-
Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17a and rat NADPH-P450 reductase
-
Shet, M. S., and Fisher, C. W., Arlotto, M. P., Shackleton, C. H. L., Holmans, P. L., Martin-Wixtrom, C. A., Saeki, Y., and Estabrook, R. W. (1994) Purification and enzymatic properties of a recombinant fusion protein expressed in Escherichia coli containing the domains of bovine P450 17a and rat NADPH-P450 reductase. Arch. Biochem. Biophys. 311, 402-417.
-
(1994)
Arch. Biochem. Biophys.
, vol.311
, pp. 402-417
-
-
Shet, M.S.1
Fisher, C.W.2
Arlotto, M.P.3
Shackleton, C.H.L.4
Holmans, P.L.5
Martin-Wixtrom, C.A.6
Saeki, Y.7
Estabrook, R.W.8
-
42
-
-
0028987970
-
The effects of cytochrome b(5), NADPH-P450 reductase, and lipid on the rate of 6-beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein
-
Shet, M. S., and Faulkner, K. M., Holmans, P. L., Fisher, C. W., and Estabrook, R. W. (1995) The effects of cytochrome b(5), NADPH-P450 reductase, and lipid on the rate of 6-beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein. Arch. Biochem. Biophys. 318, 314-321.
-
(1995)
Arch. Biochem. Biophys.
, vol.318
, pp. 314-321
-
-
Shet, M.S.1
Faulkner, K.M.2
Holmans, P.L.3
Fisher, C.W.4
Estabrook, R.W.5
-
43
-
-
0029665111
-
The omega-hydroxylation of lauric acid: Oxidation of 12-hydroxylauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase
-
Shet, M. S., and Fisher, C. W., Holmans, P. L., and Estabrook, R. W. (1996) The omega-hydroxylation of lauric acid: Oxidation of 12-hydroxylauric acid to dodecanedioic acid by a purified recombinant fusion protein containing P450 4A1 and NADPH-P450 reductase. Arch. Biochem. Biophys. 330, 199-208.
-
(1996)
Arch. Biochem. Biophys.
, vol.330
, pp. 199-208
-
-
Shet, M.S.1
Fisher, C.W.2
Holmans, P.L.3
Estabrook, R.W.4
-
44
-
-
0035582254
-
Expression, purification, and biochemical characterization of a human cytochrome P450CYP2D6-NADPH cytochrome P450 reductase fusion protein
-
Deeni, Y. Y., Paine, M. J. I., Ayrton, A. D., and Clarke, S. E., Chenery, R., and Wolf, C. R. (2001) Expression, purification, and biochemical characterization of a human cytochrome P450CYP2D6-NADPH cytochrome P450 reductase fusion protein. Arch. Biochem. Biophys. 396, 16-24.
-
(2001)
Arch. Biochem. Biophys.
, vol.396
, pp. 16-24
-
-
Deeni, Y.Y.1
Paine, M.J.I.2
Ayrton, A.D.3
Clarke, S.E.4
Chenery, R.5
Wolf, C.R.6
-
45
-
-
34548481755
-
Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-cytochrome p450 oxidoreductase, and cytochrome b(5)
-
Inui, H., Maeda, A., and Ohkawa, H. (2007) Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-Cytochrome p450 oxidoreductase, and cytochrome b(5). Biochemistry 46, 10213-10221.
-
(2007)
Biochemistry
, vol.46
, pp. 10213-10221
-
-
Inui, H.1
Maeda, A.2
Ohkawa, H.3
-
46
-
-
0034595407
-
Biochemical characterization of rat P4502C11 fused to rat or bacterial NADPH-P450 reductase domains
-
Helvig, C., and Capdevila, J. H. (2000) Biochemical characterization of rat P4502C11 fused to rat or bacterial NADPH-P450 reductase domains. Biochemistry 39, 5196-5205.
-
(2000)
Biochemistry
, vol.39
, pp. 5196-5205
-
-
Helvig, C.1
Capdevila, J.H.2
-
47
-
-
84977992599
-
The impact of linker length on P450 fusion constructs: Activity, stability and coupling
-
Hoffmann, S. M., and Weissenborn, M. J., Gricman, L., Notonier, S., Pleiss, J., and Hauer, B. (2016) The Impact of Linker Length on P450 Fusion Constructs: Activity, Stability and Coupling. ChemCatChem 8, 1591-1597.
-
(2016)
ChemCatChem
, vol.8
, pp. 1591-1597
-
-
Hoffmann, S.M.1
Weissenborn, M.J.2
Gricman, L.3
Notonier, S.4
Pleiss, J.5
Hauer, B.6
-
48
-
-
84937605477
-
Design and improvement of artificial redox modules by molecular fusion of flavodoxin and flavodoxin reductase from Escherichia coli
-
Bakkes, P. J., Biemann, S., Bokel, A., Eickholt, M., Girhard, M., and Urlacher, V. B. (2015) Design and improvement of artificial redox modules by molecular fusion of flavodoxin and flavodoxin reductase from Escherichia coli. Sci. Rep. 5, 12158.
-
(2015)
Sci. Rep.
, vol.5
, pp. 12158
-
-
Bakkes, P.J.1
Biemann, S.2
Bokel, A.3
Eickholt, M.4
Girhard, M.5
Urlacher, V.B.6
-
49
-
-
84904094364
-
P-link: A method for generating multicomponent cytochrome P450 fusions with variable linker length
-
Belsare, K. D., and Ruff, A. J., Martinez, R., Shivange, A. V., Mundhada, H., Holtmann, D., Schrader, J., and Schwaneberg, U. (2014) P-Link: A method for generating multicomponent cytochrome P450 fusions with variable linker length. BioTechniques 57, 13-20.
-
(2014)
BioTechniques
, vol.57
, pp. 13-20
-
-
Belsare, K.D.1
Ruff, A.J.2
Martinez, R.3
Shivange, A.V.4
Mundhada, H.5
Holtmann, D.6
Schrader, J.7
Schwaneberg, U.8
-
50
-
-
33745966649
-
Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from rhodococcus sp NCIMB 9784
-
Nodate, M., Kubota, M., and Misawa, N. (2006) Functional expression system for cytochrome P450 genes using the reductase domain of self-sufficient P450RhF from Rhodococcus sp NCIMB 9784. Appl. Microbiol. Biotechnol. 71, 455-462.
-
(2006)
Appl. Microbiol. Biotechnol.
, vol.71
, pp. 455-462
-
-
Nodate, M.1
Kubota, M.2
Misawa, N.3
-
51
-
-
77951723377
-
LICRED: A versatile drop-in vector for rapid generation of redox-self-sufficient cytochrome P450s
-
Sabbadin, F., Hyde, R., Robin, A., Hilgarth, E. M., Delenne, M., Flitsch, S., Turner, N., Grogan, G., and Bruce, N. C. (2010) LICRED: A Versatile Drop-In Vector for Rapid Generation of Redox-Self-Sufficient Cytochrome P450s. ChemBioChem 11, 987-994.
-
(2010)
ChemBioChem
, vol.11
, pp. 987-994
-
-
Sabbadin, F.1
Hyde, R.2
Robin, A.3
Hilgarth, E.M.4
Delenne, M.5
Flitsch, S.6
Turner, N.7
Grogan, G.8
Bruce, N.C.9
-
52
-
-
84871197071
-
A gene-fusion approach to enabling plant cytochromes P450 for biocatalysis
-
Schuckel, J., and Rylott, E. L., Grogan, G., and Bruce, N. C. (2012) A Gene-Fusion Approach to Enabling Plant Cytochromes P450 for Biocatalysis. ChemBioChem 13, 2758-2763.
-
(2012)
ChemBioChem
, vol.13
, pp. 2758-2763
-
-
Schuckel, J.1
Rylott, E.L.2
Grogan, G.3
Bruce, N.C.4
-
53
-
-
59849100963
-
Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
-
Tanvir, S., Pantigny, J., Boulnois, P., and Pulvin, S. (2009) Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications. J. Membr. Sci. 329, 85-90.
-
(2009)
J. Membr. Sci.
, vol.329
, pp. 85-90
-
-
Tanvir, S.1
Pantigny, J.2
Boulnois, P.3
Pulvin, S.4
-
54
-
-
84880122011
-
Enzyme immobilisation in biocatalysis: Why, what and how
-
Sheldon, R. A., and van Pelt, S. (2013) Enzyme immobilisation in biocatalysis: why, what and how. Chem. Soc. Rev. 42, 6223-6235.
-
(2013)
Chem. Soc. Rev.
, vol.42
, pp. 6223-6235
-
-
Sheldon, R.A.1
Van Pelt, S.2
-
55
-
-
77955168936
-
Molecular assembly of P450 with ferredoxin and ferredoxin reductase by fusion to PCNA
-
Hirakawa, H., and Nagamune, T. (2010) Molecular Assembly of P450 with Ferredoxin and Ferredoxin Reductase by Fusion to PCNA. ChemBioChem 11, 1517-1520.
-
(2010)
ChemBioChem
, vol.11
, pp. 1517-1520
-
-
Hirakawa, H.1
Nagamune, T.2
-
56
-
-
84924167095
-
Supramolecular protein assembly supports immobilization of a cytochrome P450 monooxygenase system as water-insoluble gel
-
Tan, C. Y., Hirakawa, H., and Nagamune, T. (2015) Supramolecular protein assembly supports immobilization of a cytochrome P450 monooxygenase system as water-insoluble gel. Sci. Rep. 5, 8648.
-
(2015)
Sci. Rep.
, vol.5
, pp. 8648
-
-
Tan, C.Y.1
Hirakawa, H.2
Nagamune, T.3
-
57
-
-
84995804469
-
Immobilization of a bacterial cytochrome P450 monooxygenase system on a solid support
-
Tan, C. Y., Hirakawa, H., Suzuki, R., Haga, T., Iwata, F., and Nagamune, T. (2016) Immobilization of a bacterial cytochrome P450 monooxygenase system on a solid support. Angew. Chem., Int. Ed. 55, 15002-15006.
-
(2016)
Angew. Chem., Int. Ed.
, vol.55
, pp. 15002-15006
-
-
Tan, C.Y.1
Hirakawa, H.2
Suzuki, R.3
Haga, T.4
Iwata, F.5
Nagamune, T.6
-
58
-
-
84881251451
-
Quantified high-throughput screening of Escherichia coli producing poly(3-hydroxybutyrate) based on FACS
-
Lee, J. H., and Lee, S. H., Yim, S. S., Kang, K.-H., and Lee, S. Y., Park, S. J., and Jeong, K. J. (2013) Quantified High-Throughput Screening of Escherichia coli Producing Poly(3-hydroxybutyrate) Based on FACS. Appl. Biochem. Biotechnol. 170, 1767-1779.
-
(2013)
Appl. Biochem. Biotechnol.
, vol.170
, pp. 1767-1779
-
-
Lee, J.H.1
Lee, S.H.2
Yim, S.S.3
Kang, K.-H.4
Lee, S.Y.5
Park, S.J.6
Jeong, K.J.7
-
59
-
-
0023690652
-
Cloning and expression in Escherichia coli of the alcaligenes eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway
-
Slater, S. C., and Voige, W. H., and Dennis, D. E. (1988) Cloning and expression in Escherichia coli of the Alcaligenes eutrophus H16 poly-beta-hydroxybutyrate biosynthetic pathway. J. Bacteriol. 170, 4431-4436.
-
(1988)
J. Bacteriol.
, vol.170
, pp. 4431-4436
-
-
Slater, S.C.1
Voige, W.H.2
Dennis, D.E.3
-
60
-
-
84918517847
-
New platform for cytochrome P450 reaction combining in situ immobilization on biopolymer
-
Lee, J. H., and Nam, D. H., Lee, S. H., Park, J. H., and Park, S. J., Lee, S. H., Park, C. B., and Jeong, K. J. (2014) New Platform for Cytochrome P450 Reaction Combining in Situ Immobilization on Biopolymer. Bioconjugate Chem. 25, 2101-2104.
-
(2014)
Bioconjugate Chem.
, vol.25
, pp. 2101-2104
-
-
Lee, J.H.1
Nam, D.H.2
Lee, S.H.3
Park, J.H.4
Park, S.J.5
Lee, S.H.6
Park, C.B.7
Jeong, K.J.8
-
61
-
-
84951845403
-
Solar-to-chemical conversion platform by robust cytochrome P450-P(3HB) complex
-
Lee, J. H., and Nam, D. H., Lee, S. H., Park, J. H., and Park, C. B., and Jeong, K. J. (2016) Solar-to-chemical conversion platform by Robust Cytochrome P450-P(3HB) complex. J. Ind. Eng. Chem. 33, 28-32.
-
(2016)
J. Ind. Eng. Chem.
, vol.33
, pp. 28-32
-
-
Lee, J.H.1
Nam, D.H.2
Lee, S.H.3
Park, J.H.4
Park, C.B.5
Jeong, K.J.6
-
62
-
-
33745425331
-
Replacement of the natural cofactors by selected hydrogen peroxide donors or organic peroxides results in improved activity for CYP3A4 and CYP2D6
-
Chefson, A., Zhao, J., and Auclair, K. (2006) Replacement of the natural cofactors by selected hydrogen peroxide donors or organic peroxides results in improved activity for CYP3A4 and CYP2D6. ChemBioChem 7, 916-919.
-
(2006)
ChemBioChem
, vol.7
, pp. 916-919
-
-
Chefson, A.1
Zhao, J.2
Auclair, K.3
-
63
-
-
78650440330
-
Photooxidation of cytochrome P450-BM3
-
Ener, M. E., and Lee, Y. T., Winkler, J. R., Gray, H. B., and Cheruzel, L. (2010) Photooxidation of cytochrome P450-BM3. Proc. Natl. Acad. Sci. U. S. A. 107, 18783-18786.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 18783-18786
-
-
Ener, M.E.1
Lee, Y.T.2
Winkler, J.R.3
Gray, H.B.4
Cheruzel, L.5
-
64
-
-
84885103738
-
An efficient light-driven P450 BM3 biocatalyst
-
Tran, N.-H., Nguyen, D., Dwaraknath, S., Mahadevan, S., Chavez, G., Nguyen, A., Dao, T., Mullen, S., Nguyen, T.-A., and Cheruzel, L. E. (2013) An Efficient Light-Driven P450 BM3 Biocatalyst. J. Am. Chem. Soc. 135, 14484-14487.
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 14484-14487
-
-
Tran, N.-H.1
Nguyen, D.2
Dwaraknath, S.3
Mahadevan, S.4
Chavez, G.5
Nguyen, A.6
Dao, T.7
Mullen, S.8
Nguyen, T.-A.9
Cheruzel, L.E.10
-
65
-
-
84908555867
-
Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalyst yielding a valuable synthon for natural product synthesis
-
Kato, M., Nguyen, D., Gonzalez, M., Cortez, A., and Mullen, S. E., and Cheruzel, L. E. (2014) Regio- and stereoselective hydroxylation of 10-undecenoic acid with a light-driven P450 BM3 biocatalyst yielding a valuable synthon for natural product synthesis. Bioorg. Med. Chem. 22, 5687-5691.
-
(2014)
Bioorg. Med. Chem.
, vol.22
, pp. 5687-5691
-
-
Kato, M.1
Nguyen, D.2
Gonzalez, M.3
Cortez, A.4
Mullen, S.E.5
Cheruzel, L.E.6
-
66
-
-
84920771048
-
Cofactor-free light-driven whole-cell cytochrome P450 catalysis
-
Park, J. H., and Lee, S. H., Cha, G. S., Choi, D. S., and Nam, D. H., Lee, J. H., Lee, J.-K., Yun, C.-H., Jeong, K. J., and Park, C. B. (2015) Cofactor-Free Light-Driven Whole-Cell Cytochrome P450 Catalysis. Angew. Chem., Int. Ed. 54, 969-973.
-
(2015)
Angew. Chem., Int. Ed.
, vol.54
, pp. 969-973
-
-
Park, J.H.1
Lee, S.H.2
Cha, G.S.3
Choi, D.S.4
Nam, D.H.5
Lee, J.H.6
Lee, J.-K.7
Yun, C.-H.8
Jeong, K.J.9
Park, C.B.10
-
67
-
-
79961085133
-
Light-driven cytochrome P450 hydroxylations
-
Jensen, K., and Jensen, P. E., and Møller, B. L. (2011) Light-Driven Cytochrome P450 Hydroxylations. ACS Chem. Biol. 6, 533-539.
-
(2011)
ACS Chem. Biol.
, vol.6
, pp. 533-539
-
-
Jensen, K.1
Jensen, P.E.2
Møller, B.L.3
-
68
-
-
84856217991
-
Photosystem I from plants as a bacterial cytochrome P450 surrogate electron donor: Terminal hydroxylation of branched hydrocarbon chains
-
Jensen, K., and Johnston, J. B., de Montellano, P. R. O., and Moller, B. L. (2012) Photosystem I from plants as a bacterial cytochrome P450 surrogate electron donor: terminal hydroxylation of branched hydrocarbon chains. Biotechnol. Lett. 34, 239-245.
-
(2012)
Biotechnol. Lett.
, vol.34
, pp. 239-245
-
-
Jensen, K.1
Johnston, J.B.2
De Montellano, P.R.O.3
Moller, B.L.4
-
69
-
-
84947064612
-
Metabolic engineering of light-driven cytochrome P450 dependent pathways into synechocystis sp PCC 6803
-
Wlodarczyk, A., Gnanasekaran, T., Nielsen, A. Z., and Zulu, N. N., Mellor, S. B., Luckner, M., Thofner, J. F. B., Olsen, C. E., Mottawie, M. S., Burowa, M., Pribil, M., Feussner, I., Moller, B. L., and Jensen, P. E. (2016) Metabolic engineering of light-driven cytochrome P450 dependent pathways into Synechocystis sp PCC 6803. Metab. Eng. 33, 1-11.
-
(2016)
Metab. Eng.
, vol.33
, pp. 1-11
-
-
Wlodarczyk, A.1
Gnanasekaran, T.2
Nielsen, A.Z.3
Zulu, N.N.4
Mellor, S.B.5
Luckner, M.6
Thofner, J.F.B.7
Olsen, C.E.8
Mottawie, M.S.9
Burowa, M.10
Pribil, M.11
Feussner, I.12
Moller, B.L.13
Jensen, P.E.14
-
70
-
-
84978734595
-
Fusion of ferredoxin and cytochrome P450 enables direct light-driven biosynthesis
-
Mellor, S. B., and Nielsen, A. Z., Burow, M., Motawia, M. S., Jakubauskas, D., Møller, B. L., and Jensen, P. E. (2016) Fusion of Ferredoxin and Cytochrome P450 Enables Direct Light-Driven Biosynthesis. ACS Chem. Biol. 11, 1862-1869.
-
(2016)
ACS Chem. Biol.
, vol.11
, pp. 1862-1869
-
-
Mellor, S.B.1
Nielsen, A.Z.2
Burow, M.3
Motawia, M.S.4
Jakubauskas, D.5
Møller, B.L.6
Jensen, P.E.7
-
71
-
-
23744475412
-
Recent advances in the bioremediation of persistent organic pollutants via biomolecular engineering
-
Ang, E. L., Zhao, H., and Obbard, J. P. (2005) Recent advances in the bioremediation of persistent organic pollutants via biomolecular engineering. Enzyme Microb. Technol. 37, 487-496.
-
(2005)
Enzyme Microb. Technol.
, vol.37
, pp. 487-496
-
-
Ang, E.L.1
Zhao, H.2
Obbard, J.P.3
-
72
-
-
0028085833
-
Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450
-
Shou, M., and Korzekwa, K. R., Krausz, K. W., Crespi, C. L., and Gonzalez, F. J., and Gelboin, H. V. (1994) Regio- and stereo-selective metabolism of phenanthrene by twelve cDNA-expressed human, rodent, and rabbit cytochromes P-450. Cancer Lett. 83, 305-313.
-
(1994)
Cancer Lett.
, vol.83
, pp. 305-313
-
-
Shou, M.1
Korzekwa, K.R.2
Krausz, K.W.3
Crespi, C.L.4
Gonzalez, F.J.5
Gelboin, H.V.6
-
73
-
-
0029123430
-
Metabolism of highly persistent PCB congener, 2,4,5,2',4',5'-hexachlorobiphenyl, by human CYP2B6
-
Ariyoshi, N., Oguri, K., Koga, N., Yoshimura, H., and Funae, Y. (1995) Metabolism of highly persistent PCB congener, 2,4,5,2',4',5'-hexachlorobiphenyl, by human CYP2B6. Biochem. Biophys. Res. Commun. 212, 455-460.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.212
, pp. 455-460
-
-
Ariyoshi, N.1
Oguri, K.2
Koga, N.3
Yoshimura, H.4
Funae, Y.5
-
74
-
-
34248645986
-
The involvement of cytochrome P450 system in the fate of 2,4,6-trinitrotoluene (TNT) in European eel [Anguilla Anguilla (Linnaeus, 1758)]
-
Torre, C. D., Corsi, I., Alcaro, L., Amato, E., and Focardi, S. (2006) The involvement of cytochrome P450 system in the fate of 2,4,6-trinitrotoluene (TNT) in European eel [Anguilla anguilla (Linnaeus, 1758)]. Biochem. Soc. Trans. 34, 1228.
-
(2006)
Biochem. Soc. Trans.
, vol.34
, pp. 1228
-
-
Torre, C.D.1
Corsi, I.2
Alcaro, L.3
Amato, E.4
Focardi, S.5
-
75
-
-
32344440055
-
An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX
-
Rylott, E. L., and Jackson, R. G., Edwards, J., Womack, G. L., Seth-Smith, H. M., Rathbone, D. A., Strand, S. E., and Bruce, N. C. (2006) An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX. Nat. Biotechnol. 24, 216-219.
-
(2006)
Nat. Biotechnol.
, vol.24
, pp. 216-219
-
-
Rylott, E.L.1
Jackson, R.G.2
Edwards, J.3
Womack, G.L.4
Seth-Smith, H.M.5
Rathbone, D.A.6
Strand, S.E.7
Bruce, N.C.8
-
76
-
-
84996487076
-
Characterization of a cytochrome P450 monooxygenase capable of high molecular weight PAHs oxidization from rhodococcus sp. P14
-
Luo, A., Wu, Y.-R., Xu, Y., Kan, J., Qiao, J., Liang, L., Huang, T., and Hu, Z. (2016) Characterization of a cytochrome P450 monooxygenase capable of high molecular weight PAHs oxidization from Rhodococcus sp. P14. Process Biochem., DOI: 10.1016/j.procbio.2016.07.024.
-
(2016)
Process Biochem.
-
-
Luo, A.1
Wu, Y.-R.2
Xu, Y.3
Kan, J.4
Qiao, J.5
Liang, L.6
Huang, T.7
Hu, Z.8
-
77
-
-
84974808862
-
Biodegradation of the fungicide propiconazole by pseudomonas aeruginosa PS-4 strain isolated from a paddy soil
-
Satapute, P., and Kaliwal, B. (2016) Biodegradation of the fungicide propiconazole by Pseudomonas aeruginosa PS-4 strain isolated from a paddy soil. Ann. Microbiol. 66, 1355.
-
(2016)
Ann. Microbiol.
, vol.66
, pp. 1355
-
-
Satapute, P.1
Kaliwal, B.2
-
78
-
-
0014527682
-
Enzymatic degradation of diazinon by rat liver microsomes
-
Yang, R. S. H., and Dauterman, W. C., and Hodgson, E. (1969) Enzymatic degradation of diazinon by rat liver microsomes. Life Sci. 8, 667-672.
-
(1969)
Life Sci.
, vol.8
, pp. 667-672
-
-
Yang, R.S.H.1
Dauterman, W.C.2
Hodgson, E.3
-
79
-
-
0036578528
-
Biodegradation of polychlorinated dibenzo-p-dioxins by recombinant yeast expressing rat CYP1A subfamily
-
Sakaki, T., Shinkyo, R., Takita, T., Ohta, M., and Inouye, K. (2002) Biodegradation of polychlorinated dibenzo-p-dioxins by recombinant yeast expressing rat CYP1A subfamily. Arch. Biochem. Biophys. 401, 91-98.
-
(2002)
Arch. Biochem. Biophys.
, vol.401
, pp. 91-98
-
-
Sakaki, T.1
Shinkyo, R.2
Takita, T.3
Ohta, M.4
Inouye, K.5
-
80
-
-
84961184149
-
Metagenomic and functional analyses of the consequences of reduction of bacterial diversity on soil functions and bioremediation in diesel-contaminated microcosms
-
Jung, J., Philippot, L., and Park, W. (2016) Metagenomic and functional analyses of the consequences of reduction of bacterial diversity on soil functions and bioremediation in diesel-contaminated microcosms. Sci. Rep. 6, 23012.
-
(2016)
Sci. Rep.
, vol.6
, pp. 23012
-
-
Jung, J.1
Philippot, L.2
Park, W.3
-
81
-
-
84855714036
-
Metagenomic analysis of the bioremediation of diesel-contaminated Canadian high arctic soils
-
Yergeau, E., Sanschagrin, S., Beaumier, D., and Greer, C. W. (2012) Metagenomic Analysis of the Bioremediation of Diesel-Contaminated Canadian High Arctic Soils. PLoS One 7, e30058.
-
(2012)
PLoS One
, vol.7
, pp. e30058
-
-
Yergeau, E.1
Sanschagrin, S.2
Beaumier, D.3
Greer, C.W.4
-
82
-
-
84963815343
-
Bioaccumulation of HMW PAHs in the roots of wild blackberry from the bor region (Serbia): Phytoremediation and biomonitoring aspects
-
Alagic, S. C., Jovanovic, V. P. S., Mitic, V. D., and Cvetkovic, J. S., Petrovic, G. M., and Stojanovic, G. S. (2016) Bioaccumulation of HMW PAHs in the roots of wild blackberry from the Bor region (Serbia): Phytoremediation and biomonitoring aspects. Sci. Total Environ. 562, 561-570.
-
(2016)
Sci. Total Environ.
, vol.562
, pp. 561-570
-
-
Alagic, S.C.1
Jovanovic, V.P.S.2
Mitic, V.D.3
Cvetkovic, J.S.4
Petrovic, G.M.5
Stojanovic, G.S.6
-
83
-
-
0033231710
-
Environmental behavior of explosives in groundwater from the milan army ammunition plant in aquatic and wetland plant treatments
-
Best, E. P. H., and Sprecher, S. L., Larson, S. L., Fredrickson, H. L., and Bader, D. F. (1999) Environmental behavior of explosives in groundwater from the Milan Army Ammunition Plant in aquatic and wetland plant treatments. Uptake and fate of TNT and RDX in plants. Chemosphere 39, 2057-2072.
-
(1999)
Uptake and Fate of TNT and RDX in Plants. Chemosphere
, vol.39
, pp. 2057-2072
-
-
Best, E.P.H.1
Sprecher, S.L.2
Larson, S.L.3
Fredrickson, H.L.4
Bader, D.F.5
-
84
-
-
0032816181
-
Herbicide metabolism and cross-tolerance in transgenic potato plants expressing human CYP1A1
-
Inui, H., Ueyama, Y., Shiota, N., Okhawa, Y., and Ohkawa, H. (1999) Herbicide metabolism and cross-tolerance in transgenic potato plants expressing human CYP1A1. Pestic. Biochem. Physiol. 64, 33-46.
-
(1999)
Pestic. Biochem. Physiol.
, vol.64
, pp. 33-46
-
-
Inui, H.1
Ueyama, Y.2
Shiota, N.3
Okhawa, Y.4
Ohkawa, H.5
-
85
-
-
0032813363
-
Engineering and biochemical characterization of the rat microsomal cytochrome P4501A1 fused to ferredoxin and ferredoxin-NADP(+) reductase from plant chloroplasts
-
Lacour, T., and Ohkawa, H. (1999) Engineering and biochemical characterization of the rat microsomal cytochrome P4501A1 fused to ferredoxin and ferredoxin-NADP(+) reductase from plant chloroplasts. Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol. 1433, 87-102.
-
(1999)
Biochim. Biophys. Acta, Protein Struct. Mol. Enzymol.
, vol.1433
, pp. 87-102
-
-
Lacour, T.1
Ohkawa, H.2
-
86
-
-
0034008241
-
Herbicide metabolism and cross-tolerance in transgenic potato plants co-expressing human CYP1A1, CYP2B6, and CYP2C19
-
Inui, H., Kodama, T., Ohkawa, Y., and Ohkawa, H. (2000) Herbicide metabolism and cross-tolerance in transgenic potato plants co-expressing human CYP1A1, CYP2B6, and CYP2C19. Pestic. Biochem. Physiol. 66, 116-129.
-
(2000)
Pestic. Biochem. Physiol.
, vol.66
, pp. 116-129
-
-
Inui, H.1
Kodama, T.2
Ohkawa, Y.3
Ohkawa, H.4
-
87
-
-
0035649032
-
Metabolism of herbicides and other chemicals in human cytochrome P450 species and in transgenic potato plants co-expressing human CYP1A1, CYP2B6 and CYP2C19
-
Inui, H., Shiota, N., Motoi, Y., Ido, Y., Inoue, T., Kodama, T., Ohkawa, Y., and Ohkawa, H. (2001) Metabolism of herbicides and other chemicals in human cytochrome P450 species and in transgenic potato plants co-expressing human CYP1A1, CYP2B6 and CYP2C19. J. Pestic. Sci. 26, 28-40.
-
(2001)
J. Pestic. Sci.
, vol.26
, pp. 28-40
-
-
Inui, H.1
Shiota, N.2
Motoi, Y.3
Ido, Y.4
Inoue, T.5
Kodama, T.6
Ohkawa, Y.7
Ohkawa, H.8
-
88
-
-
19944384932
-
Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides
-
Hirose, S., Kawahigashi, H., Ozawa, K., Shiota, N., Inui, H., Ohkawa, H., and Ohkawa, Y. (2005) Transgenic rice containing human CYP2B6 detoxifies various classes of herbicides. J. Agric. Food Chem. 53, 3461-3467.
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 3461-3467
-
-
Hirose, S.1
Kawahigashi, H.2
Ozawa, K.3
Shiota, N.4
Inui, H.5
Ohkawa, H.6
Ohkawa, Y.7
-
89
-
-
28444482841
-
Phytoremediation of metolachlor by transgenic rice plants expressing human CYP2B6
-
Kawahigashi, H., Hirose, S., Ohkawa, H., and Ohkawa, Y. (2005) Phytoremediation of metolachlor by transgenic rice plants expressing human CYP2B6. J. Agric. Food Chem. 53, 9155-9160.
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 9155-9160
-
-
Kawahigashi, H.1
Hirose, S.2
Ohkawa, H.3
Ohkawa, Y.4
-
90
-
-
27744514079
-
Transgenic rice plants expressing human CYP1A1 remediate the triazine herbicides atrazine and simazine
-
Kawahigashi, H., Hirose, S., Ohkawa, H., and Ohkawa, Y. (2005) Transgenic rice plants expressing human CYP1A1 remediate the triazine herbicides atrazine and simazine. J. Agric. Food Chem. 53, 8557-8564.
-
(2005)
J. Agric. Food Chem.
, vol.53
, pp. 8557-8564
-
-
Kawahigashi, H.1
Hirose, S.2
Ohkawa, H.3
Ohkawa, Y.4
-
91
-
-
80053223746
-
Engineering plants for the phytoremediation of RDX in the presence of the co-contaminating explosive TNT
-
Rylott, E. L., and Budarina, M. V., Barker, A., Lorenz, A., Strand, S. E., and Bruce, N. C. (2011) Engineering plants for the phytoremediation of RDX in the presence of the co-contaminating explosive TNT. New Phytol. 192, 405-413.
-
(2011)
New Phytol.
, vol.192
, pp. 405-413
-
-
Rylott, E.L.1
Budarina, M.V.2
Barker, A.3
Lorenz, A.4
Strand, S.E.5
Bruce, N.C.6
-
92
-
-
0035653258
-
Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons
-
Li, Q. S., Ogawa, J., Schmid, R. D., and Shimizu, S. (2001) Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons. Appl. Environ. Microbiol. 67, 5735-5739.
-
(2001)
Appl. Environ. Microbiol.
, vol.67
, pp. 5735-5739
-
-
Li, Q.S.1
Ogawa, J.2
Schmid, R.D.3
Shimizu, S.4
-
93
-
-
84883226591
-
Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons
-
Syed, K., Porollo, A., Miller, D., and Yadav, J. S. (2013) Rational engineering of the fungal P450 monooxygenase CYP5136A3 to improve its oxidizing activity toward polycyclic aromatic hydrocarbons. Protein Eng., Des. Sel. 26, 553-557.
-
(2013)
Protein Eng., Des. Sel.
, vol.26
, pp. 553-557
-
-
Syed, K.1
Porollo, A.2
Miller, D.3
Yadav, J.S.4
-
94
-
-
0035081039
-
Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cyto-chrome P450cam)
-
Jones, J. P., O'Hare, E. J., and Wong, L. L. (2001) Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cyto-chrome P450cam). Eur. J. Biochem. 268, 1460-1467.
-
(2001)
Eur. J. Biochem.
, vol.268
, pp. 1460-1467
-
-
Jones, J.P.1
O'Hare, E.J.2
Wong, L.L.3
-
95
-
-
84882286824
-
Regioselective o-hydroxylation of monosubstituted benzenes by P450 BM3
-
Dennig, A., Lulsdorf, N., Liu, H., and Schwaneberg, U. (2013) Regioselective o-Hydroxylation of Monosubstituted Benzenes by P450 BM3. Angew. Chem., Int. Ed. 52, 8459-8462.
-
(2013)
Angew. Chem., Int. Ed.
, vol.52
, pp. 8459-8462
-
-
Dennig, A.1
Lulsdorf, N.2
Liu, H.3
Schwaneberg, U.4
-
96
-
-
84859245861
-
Protein and RNA engineering to customize microbial molecular reporting
-
Gredell, J. A., and Frei, C. S., and Cirino, P. C. (2012) Protein and RNA engineering to customize microbial molecular reporting. Biotechnol. J. 7, 477-499.
-
(2012)
Biotechnol. J.
, vol.7
, pp. 477-499
-
-
Gredell, J.A.1
Frei, C.S.2
Cirino, P.C.3
-
97
-
-
67649574151
-
Electrochemistry of cytochromes P450: Analysis of current-voltage characteristics of electrodes with immobilized cytochromes P450 for the screening of substrates and inhibitors
-
Shumyantseva, V. V., and Bulko, T. V., Kuznetsova, G. P., Samenkova, N. F., and Archakov, A. I. (2009) Electrochemistry of cytochromes P450: Analysis of current-voltage characteristics of electrodes with immobilized cytochromes P450 for the screening of substrates and inhibitors. Biochemistry (Moscow) 74, 438-444.
-
(2009)
Biochemistry (Moscow)
, vol.74
, pp. 438-444
-
-
Shumyantseva, V.V.1
Bulko, T.V.2
Kuznetsova, G.P.3
Samenkova, N.F.4
Archakov, A.I.5
-
98
-
-
84924386392
-
Cytochrome P450 bienzymes assembled on au/chitosan/reduced graphene oxide nanosheets for electrochemically-driven drug cascade metabolism
-
Lu, J. S., and Cui, D. M., Li, H. N., Zhang, Y. J., and Liu, S. Q. (2015) Cytochrome P450 bienzymes assembled on Au/chitosan/reduced graphene oxide nanosheets for electrochemically-driven drug cascade metabolism. Electrochim. Acta 165, 36-44.
-
(2015)
Electrochim. Acta
, vol.165
, pp. 36-44
-
-
Lu, J.S.1
Cui, D.M.2
Li, H.N.3
Zhang, Y.J.4
Liu, S.Q.5
-
99
-
-
84884999874
-
Human cytochrome P450 3A4 and a carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions
-
Xue, Q., Kato, D., Kamata, T., Guo, Q. H., and You, T. Y., and Niwa, O. (2013) Human cytochrome P450 3A4 and a carbon nanofiber modified film electrode as a platform for the simple evaluation of drug metabolism and inhibition reactions. Analyst 138, 6463-6468.
-
(2013)
Analyst
, vol.138
, pp. 6463-6468
-
-
Xue, Q.1
Kato, D.2
Kamata, T.3
Guo, Q.H.4
You, T.Y.5
Niwa, O.6
-
100
-
-
84856301031
-
Direct electrochemistry of cytochrome P450 in a biocompatible film composed of an epoxy polymer and acetylene black
-
Dai, C. Y., and Ding, Y. L., Li, M., and Fei, J. J. (2012) Direct electrochemistry of cytochrome P450 in a biocompatible film composed of an epoxy polymer and acetylene black. Microchim. Acta 176, 397-404.
-
(2012)
Microchim. Acta
, vol.176
, pp. 397-404
-
-
Dai, C.Y.1
Ding, Y.L.2
Li, M.3
Fei, J.J.4
-
101
-
-
84863918889
-
Electrochemically driven drug metabolism via cytochrome P450 2C9 isozyme microsomes with cytochrome P450 reductase and indium tin oxide nanoparticle composites
-
Xu, X., Wei, W., Huang, M. H., Yao, L., and Liu, S. Q. (2012) Electrochemically driven drug metabolism via cytochrome P450 2C9 isozyme microsomes with cytochrome P450 reductase and indium tin oxide nanoparticle composites. Chem. Commun. 48, 7802-7804.
-
(2012)
Chem. Commun.
, vol.48
, pp. 7802-7804
-
-
Xu, X.1
Wei, W.2
Huang, M.H.3
Yao, L.4
Liu, S.Q.5
-
102
-
-
84978719360
-
Expanding an efficient, electrically driven and CNT-tagged P450 system into the third dimension: A nanowired CNT-containing and enzyme-stabilising 3D sol-gel electrode
-
Llaudet, E. C., Darimont, D., Samba, R., Matiychyn, I., Stelzle, M., Weissenborn, M. J., and Hauer, B. (2016) Expanding an Efficient, Electrically Driven and CNT-Tagged P450 System into the Third Dimension: A Nanowired CNT-Containing and Enzyme-Stabilising 3D Sol-Gel Electrode. ChemBioChem 17, 1367-1373.
-
(2016)
ChemBioChem
, vol.17
, pp. 1367-1373
-
-
Llaudet, E.C.1
Darimont, D.2
Samba, R.3
Matiychyn, I.4
Stelzle, M.5
Weissenborn, M.J.6
Hauer, B.7
-
103
-
-
67650517516
-
Electrochemically driven drug metabolism by membranes containing human cytochrome P450
-
Mie, Y., Suzuki, M., and Komatsu, Y. (2009) Electrochemically Driven Drug Metabolism by Membranes Containing Human Cytochrome P450. J. Am. Chem. Soc. 131, 6646-6647.
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 6646-6647
-
-
Mie, Y.1
Suzuki, M.2
Komatsu, Y.3
-
104
-
-
79551694936
-
Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s
-
Krishnan, S., Wasalathanthri, D., Zhao, L. L., and Schenkman, J. B., and Rusling, J. F. (2011) Efficient Bioelectronic Actuation of the Natural Catalytic Pathway of Human Metabolic Cytochrome P450s. J. Am. Chem. Soc. 133, 1459-1465.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 1459-1465
-
-
Krishnan, S.1
Wasalathanthri, D.2
Zhao, L.L.3
Schenkman, J.B.4
Rusling, J.F.5
-
105
-
-
84968860900
-
State-of-the-art metabolic toxicity screening and pathway evaluation
-
Hvastkovs, E. G., and Rusling, J. F. (2016) State-of-the-Art Metabolic Toxicity Screening and Pathway Evaluation. Anal. Chem. 88, 4584-4599.
-
(2016)
Anal. Chem.
, vol.88
, pp. 4584-4599
-
-
Hvastkovs, E.G.1
Rusling, J.F.2
-
106
-
-
84863305265
-
Metabolic toxicity screening using electrochemiluminescence arrays coupled with enzyme-DNA biocolloid reactors and liquid chromatography-mass spectrometry
-
(Cooks, R. G., and Yeung, E. S., Eds.) Annual Reviews, Palo Alto, CA
-
Hvastkovs, E. G., and Schenkman, J. B., and Rusling, J. F. (2012) Metabolic Toxicity Screening Using Electrochemiluminescence Arrays Coupled with Enzyme-DNA Biocolloid Reactors and Liquid Chromatography-Mass Spectrometry, in Annual Review of Analytical Chemistry (Cooks, R. G., and Yeung, E. S., Eds.) Vol. 5, pp 79-105, Annual Reviews, Palo Alto, CA
-
(2012)
Annual Review of Analytical Chemistry
, vol.5
, pp. 79-105
-
-
Hvastkovs, E.G.1
Schenkman, J.B.2
Rusling, J.F.3
-
107
-
-
84865792935
-
Cytochrome P450 (CYP) enzymes and the development of CYP biosensors
-
Schneider, E., and Clark, D. S. (2013) Cytochrome P450 (CYP) enzymes and the development of CYP biosensors. Biosens. Bioelectron. 39, 1-13.
-
(2013)
Biosens. Bioelectron.
, vol.39
, pp. 1-13
-
-
Schneider, E.1
Clark, D.S.2
-
108
-
-
18044384858
-
Cytochrome P450 biosensors - A review
-
Bistolas, N, Wollenberger, U., Jung, C, and Scheller, F. W. (2005) Cytochrome P450 biosensors - a review. Biosens. Bioelectron. 20, 2408-2423.
-
(2005)
Biosens. Bioelectron.
, vol.20
, pp. 2408-2423
-
-
Bistolas, N.1
Wollenberger, U.2
Jung, C.3
Scheller, F.W.4
-
109
-
-
61849106498
-
A review of the use of genetically engineered enzymes in electrochemical biosensors
-
Campas, M., Prieto-Simon, B., and Marty, J.-L. (2009) A review of the use of genetically engineered enzymes in electrochemical biosensors. Semin. Cell Dev. Biol. 20, 3-9.
-
(2009)
Semin. Cell Dev. Biol.
, vol.20
, pp. 3-9
-
-
Campas, M.1
Prieto-Simon, B.2
Marty, J.-L.3
-
110
-
-
84946035249
-
Conductive composite biosensor system for electrochemical indinavir drug detection
-
2015
-
Ross, N., Hendricks-Leukes, N., Ajayi, R. F., Baker, P., and Iwuoha, E. I. (2015) Conductive Composite Biosensor System for Electrochemical Indinavir Drug Detection. J. Chem. 2015, 1-7.
-
(2015)
J. Chem.
, pp. 1-7
-
-
Ross, N.1
Hendricks-Leukes, N.2
Ajayi, R.F.3
Baker, P.4
Iwuoha, E.I.5
-
111
-
-
59049085371
-
Novel therapeutic biosensor for indinavir - A protease inhibitor antiretroviral drug
-
Ignaszak, A, Hendricks, N, Waryo, T., Songa, E., Jahed, N, Ngece, R, Al-Ahmed, A., Kgarebe, B., Baker, P., and Iwuoha, E. I. (2009) Novel therapeutic biosensor for indinavir-A protease inhibitor antiretroviral drug. J. Pharm. Biomed. Anal. 49, 498-501.
-
(2009)
J. Pharm. Biomed. Anal.
, vol.49
, pp. 498-501
-
-
Ignaszak, A.1
Hendricks, N.2
Waryo, T.3
Songa, E.4
Jahed, N.5
Ngece, R.6
Al-Ahmed, A.7
Kgarebe, B.8
Baker, P.9
Iwuoha, E.I.10
-
112
-
-
84986203206
-
A cytochrome P450 3A4 biosensor based on generation 4.0 PAMAM dendrimers for the detection of caffeine
-
Muller, M., Agarwal, N, and Kim, J. (2016) A Cytochrome P450 3A4 Biosensor Based on Generation 4.0 PAMAM Dendrimers for the Detection of Caffeine. Biosensors 6, 44.
-
(2016)
Biosensors
, vol.6
, pp. 44
-
-
Muller, M.1
Agarwal, N.2
Kim, J.3
-
113
-
-
84903131343
-
Cytochrome P450 2D6 based electrochemical sensor for the determination of codeine
-
Asturias-Arribas, L., Alonso-Lomillo, M. A., Dominguez-Renedo, O., and Arcos-Martinez, M. J. (2014) Cytochrome P450 2D6 based electrochemical sensor for the determination of codeine. Talanta 129, 315-319.
-
(2014)
Talanta
, vol.129
, pp. 315-319
-
-
Asturias-Arribas, L.1
Alonso-Lomillo, M.A.2
Dominguez-Renedo, O.3
Arcos-Martinez, M.J.4
-
114
-
-
84886016443
-
Continuous monitoring of naproxen by a cytochrome P450-based electrochemical sensor
-
Baj-Rossi, C., Jost, T. R, Cavallini, A., Grassi, F., De Micheli, G., and Carrara, S. (2014) Continuous monitoring of Naproxen by a cytochrome P450-based electrochemical sensor. Biosens. Bioelectron. 53, 283-287.
-
(2014)
Biosens. Bioelectron.
, vol.53
, pp. 283-287
-
-
Baj-Rossi, C.1
Jost, T.R.2
Cavallini, A.3
Grassi, F.4
De Micheli, G.5
Carrara, S.6
-
115
-
-
79959797180
-
A silver nanoparticle/Poly (8-anilino-1-naphthalene sulphonic acid) bio-electrochemical biosensor system for the analytical determination of ethambutol
-
Ngece, R. F., West, N, and Ndangili, P. M., Olowu, R. A., Williams, A., Hendricks, N., Mailu, S., Baker, P., and Iwuoha, E. (2011) A silver Nanoparticle/Poly (8-Anilino-1-Naphthalene Sulphonic Acid) Bio-electrochemical Biosensor System for the Analytical Determination of Ethambutol. Int. J. Electrochem. Sci. 6, 1820-1834.
-
(2011)
Int. J. Electrochem. Sci.
, vol.6
, pp. 1820-1834
-
-
Ngece, R.F.1
West, N.2
Ndangili, P.M.3
Olowu, R.A.4
Williams, A.5
Hendricks, N.6
Mailu, S.7
Baker, P.8
Iwuoha, E.9
-
116
-
-
42649117782
-
CYP450 biosensors based on gold chips for antiepileptic drugs determination
-
Alonso-Lomillo, M. A., Gonzalo-Ruiz, J., Dominguez-Renedo, O., Munoz, F., and Arcos-Martinez, M. J. (2008) CYP450 biosensors based on gold chips for antiepileptic drugs determination. Biosens. Bioelectron. 23, 1733-1737.
-
(2008)
Biosens. Bioelectron.
, vol.23
, pp. 1733-1737
-
-
Alonso-Lomillo, M.A.1
Gonzalo-Ruiz, J.2
Dominguez-Renedo, O.3
Munoz, F.4
Arcos-Martinez, M.J.5
-
117
-
-
34547699369
-
Amperometric responses of CYP2D6 drug metabolism nanobiosensor for sertraline: A selective serotonin reuptake inhibitor
-
Iwuoha, E., Ngece, R., Klink, M., and Baker, P. (2007) Amperometric responses of CYP2D6 drug metabolism nanobiosensor for sertraline: a selective serotonin reuptake Inhibitor. IET Nanobiotechnol. 1, 62-67.
-
(2007)
IET Nanobiotechnol.
, vol.1
, pp. 62-67
-
-
Iwuoha, E.1
Ngece, R.2
Klink, M.3
Baker, P.4
-
118
-
-
84871763538
-
Electrochemical determination of cocaine using screen-printed cytochrome P450 2B4 based biosensors
-
Asturias-Arribas, L., Alonso-Lomillo, M. A., Dominguez-Renedo, O., and Arcos-Martinez, M. J. (2013) Electrochemical determination of cocaine using screen-printed cytochrome P450 2B4 based biosensors. Talanta 105, 131-134.
-
(2013)
Talanta
, vol.105
, pp. 131-134
-
-
Asturias-Arribas, L.1
Alonso-Lomillo, M.A.2
Dominguez-Renedo, O.3
Arcos-Martinez, M.J.4
-
119
-
-
78650176726
-
CYP450 biosensors based on screen-printed carbon electrodes for the determination of cocaine
-
Asturias-Arribas, L., Alonso-Lomillo, M. A., Dominguez-Renedo, O., and Arcos-Martinez, M. J. (2011) CYP450 biosensors based on screen-printed carbon electrodes for the determination of cocaine. Anal. Chim. Acta 685, 15-20.
-
(2011)
Anal. Chim. Acta
, vol.685
, pp. 15-20
-
-
Asturias-Arribas, L.1
Alonso-Lomillo, M.A.2
Dominguez-Renedo, O.3
Arcos-Martinez, M.J.4
-
120
-
-
84872466919
-
An amperometric biosensor based on human cytochrome P450 2C9 in polyacrylamide hydrogel films for bisphenol A determination
-
Sun, P. Y., and Wu, Y. H. (2013) An amperometric biosensor based on human cytochrome P450 2C9 in polyacrylamide hydrogel films for bisphenol A determination. Sens. Actuators, B 178, 113-118.
-
(2013)
Sens. Actuators, B
, vol.178
, pp. 113-118
-
-
Sun, P.Y.1
Wu, Y.H.2
-
121
-
-
59949089761
-
Mcrosomal cytochrome P450-3A4 (CYP3A4) nanobiosensor for the determination of 2,4-dichlorophenol - An endocrine disruptor compound
-
Hendricks, N. R., and Waryo, T. T., Arotiba, O., Jahed, N, Baker, P. G. L., and Iwuoha, E. I. (2009) Mcrosomal cytochrome P450-3A4 (CYP3A4) nanobiosensor for the determination of 2,4-dichlorophenol-An endocrine disruptor compound. Electrochim. Acta 54, 1925-1931.
-
(2009)
Electrochim. Acta
, vol.54
, pp. 1925-1931
-
-
Hendricks, N.R.1
Waryo, T.T.2
Arotiba, O.3
Jahed, N.4
Baker, P.G.L.5
Iwuoha, E.I.6
-
122
-
-
79958091445
-
Direct electrochemistry of cytochrome P450 6A1 in mimic bio-membrane and its application for pesticides sensing
-
Wu, Y. H. (2011) Direct electrochemistry of cytochrome P450 6A1 in mimic bio-membrane and its application for pesticides sensing. Sens. Actuators, B 156, 773-778.
-
(2011)
Sens. Actuators, B
, vol.156
, pp. 773-778
-
-
Wu, Y.H.1
-
123
-
-
78650605533
-
An amperometric biosensor based on rat cytochrome P450 1A1 for benzo a pyrene determination
-
Wu, Y. H., and Liu, X. Q., Zhang, L., and Wang, C. T. (2011) An amperometric biosensor based on rat cytochrome P450 1A1 for benzo a pyrene determination. Biosens. Bioelectron. 26, 2177-2182.
-
(2011)
Biosens. Bioelectron.
, vol.26
, pp. 2177-2182
-
-
Wu, Y.H.1
Liu, X.Q.2
Zhang, L.3
Wang, C.T.4
-
124
-
-
84943600440
-
Mimicking enzymatic effects of cytochrome P450 by an efficient biosensor for in vitro detection of DNA damage
-
Jalalvand, A. R., and Gholivand, M. B., Goicoechea, H. C., Skov, T., and Mansouri, K. (2015) Mimicking enzymatic effects of cytochrome P450 by an efficient biosensor for in vitro detection of DNA damage. Int. J. Biol. Macromol. 79, 1004-1010.
-
(2015)
Int. J. Biol. Macromol.
, vol.79
, pp. 1004-1010
-
-
Jalalvand, A.R.1
Gholivand, M.B.2
Goicoechea, H.C.3
Skov, T.4
Mansouri, K.5
-
125
-
-
35548933849
-
Rational engineering of human cytochrome P450 2B6 for enhanced expression and stability: Importance of a Leu(264)-> Phe substitution
-
Kumar, S., Zhao, Y., Sun, L., Negi, S. S., and Halpert, J. R., and Muralidhara, B. K. (2007) Rational engineering of human cytochrome P450 2B6 for enhanced expression and stability: Importance of a Leu(264)-> Phe substitution. Mol. Pharmacol. 72, 1191-1199.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 1191-1199
-
-
Kumar, S.1
Zhao, Y.2
Sun, L.3
Negi, S.S.4
Halpert, J.R.5
Muralidhara, B.K.6
-
126
-
-
84944097455
-
Whole-cell amperometric biosensor for screening of cytochrome P450 inhibitors
-
Yoetz-Kopelman, T., Porat-Ophir, C., Shacham-Diamand, Y., and Freeman, A. (2016) Whole-cell amperometric biosensor for screening of cytochrome P450 inhibitors. Sens. Actuators, B 223, 392-399.
-
(2016)
Sens. Actuators, B
, vol.223
, pp. 392-399
-
-
Yoetz-Kopelman, T.1
Porat-Ophir, C.2
Shacham-Diamand, Y.3
Freeman, A.4
-
127
-
-
0036028905
-
Optical biosensor and scanning probe microscopy studies of cytochrome P450 interactions with redox partners and phospholipid layers
-
Archakov, A. I., and Ivanov, Y. D. (2002) Optical biosensor and scanning probe microscopy studies of cytochrome P450 interactions with redox partners and phospholipid layers. Methods Enzymol. 357, 94-103.
-
(2002)
Methods Enzymol.
, vol.357
, pp. 94-103
-
-
Archakov, A.I.1
Ivanov, Y.D.2
-
128
-
-
84940510859
-
Substrate binding to cytochrome P450-2J2 in nanodiscs detected by nanoplasmonic lycurgus cup arrays
-
Plucinski, L., and Gartia, M. R., Arnold, W. R., Ameen, A., Chang, T. W., Hsiao, A., and Liu, G. L., and Das, A. (2016) Substrate binding to cytochrome P450-2J2 in Nanodiscs detected by nanoplasmonic Lycurgus cup arrays. Biosens. Bioelectron. 75, 337-346.
-
(2016)
Biosens. Bioelectron.
, vol.75
, pp. 337-346
-
-
Plucinski, L.1
Gartia, M.R.2
Arnold, W.R.3
Ameen, A.4
Chang, T.W.5
Hsiao, A.6
Liu, G.L.7
Das, A.8
-
129
-
-
84862518484
-
Microarray of human P450 with an integrated oxygen sensing film for high-throughput detection of metabolic activities
-
Chang, G., Mori, Y., Mori, S., Irie, T., Nagai, H., Goto, T., Tatsu, Y., Imaishi, H., and Morigaki, K. (2012) Microarray of Human P450 with an Integrated Oxygen Sensing Film for High-Throughput Detection of Metabolic Activities. Anal. Chem. 84, 5292-5297.
-
(2012)
Anal. Chem.
, vol.84
, pp. 5292-5297
-
-
Chang, G.1
Mori, Y.2
Mori, S.3
Irie, T.4
Nagai, H.5
Goto, T.6
Tatsu, Y.7
Imaishi, H.8
Morigaki, K.9
-
130
-
-
79954524162
-
Vertically integrated human P450 and oxygen sensing film for the assays of P450 metabolic activities
-
Chang, G., Morigaki, K., Tatsu, Y., Hikawa, T., Goto, T., and Imaishi, H. (2011) Vertically Integrated Human P450 and Oxygen Sensing Film for the Assays of P450 Metabolic Activities. Anal. Chem. 83, 2956-2963.
-
(2011)
Anal. Chem.
, vol.83
, pp. 2956-2963
-
-
Chang, G.1
Morigaki, K.2
Tatsu, Y.3
Hikawa, T.4
Goto, T.5
Imaishi, H.6
-
131
-
-
84897518404
-
SoxR as a single-cell biosensor for NADPH-consuming enzymes in Escherichia coli
-
Siedler, S., Schendzielorz, G., Binder, S., Eggeling, L., Bringer, S., and Bott, M. (2014) SoxR as a Single-Cell Biosensor for NADPH-Consuming Enzymes in Escherichia coli. ACS Synth. Biol. 3, 41-47.
-
(2014)
ACS Synth. Biol.
, vol.3
, pp. 41-47
-
-
Siedler, S.1
Schendzielorz, G.2
Binder, S.3
Eggeling, L.4
Bringer, S.5
Bott, M.6
-
132
-
-
77951107086
-
Synthetic biology: Applications come of age
-
Khalil, A. S., and Collins, J. J. (2010) Synthetic biology: applications come of age. Nat. Rev. Genet. 11, 367-379.
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 367-379
-
-
Khalil, A.S.1
Collins, J.J.2
-
133
-
-
84455202507
-
Detection of water toxicity using cytochrome P450 transgenic zebrafish as live biosensor: For polychlorinated biphenyls toxicity
-
Hung, K. W. V., Suen, M. F. K., Chen, Y. F., and Cai, H. B., Mo, Z. X., and Yung, K. K. L. (2012) Detection of water toxicity using cytochrome P450 transgenic zebrafish as live biosensor: For polychlorinated biphenyls toxicity. Biosens. Bioelectron. 31, 548-553.
-
(2012)
Biosens. Bioelectron.
, vol.31
, pp. 548-553
-
-
Hung, K.W.V.1
Suen, M.F.K.2
Chen, Y.F.3
Cai, H.B.4
Mo, Z.X.5
Yung, K.K.L.6
-
134
-
-
0001477412
-
-
(Adolph, K. W., Ed.) Academic Press, Orlando, FL
-
Shimada, T., Oda, Y., Yamazaki, H., Mimura, M., and Guengerich, F. P. (1994) SOS function tests for studies of chemical carcinogenesis in Salmonella typhimurium TA 1535/pSK1002, NM2009, and NM3009 Methods in Molecular Genetics, Gene and Chromosome Analysis (Adolph, K. W., Ed.) Vol. 5, pp 342-355, Academic Press, Orlando, FL.
-
(1994)
SOS Function Tests for Studies of Chemical Carcinogenesis in Salmonella Typhimurium TA 1535/pSK1002, NM2009, and NM3009 Methods in Molecular Genetics, Gene and Chromosome Analysis
, vol.5
, pp. 342-355
-
-
Shimada, T.1
Oda, Y.2
Yamazaki, H.3
Mimura, M.4
Guengerich, F.P.5
-
135
-
-
0021891433
-
Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens
-
Oda, Y., Nakamura, S.-i., Oki, I., Kato, T., and Shinagawa, H. (1985) Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens. Mutat. Res. 147, 219-229.
-
(1985)
Mutat. Res.
, vol.147
, pp. 219-229
-
-
Oda, Y.1
Nakamura, S.-I.2
Oki, I.3
Kato, T.4
Shinagawa, H.5
-
136
-
-
0032967962
-
Development of a new genotoxicity test system with salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase
-
Aryal, P., Yoshikawa, K., Terashita, T., Guengerich, F. P., Shimada, T., and Oda, Y. (1999) Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 442, 113-120.
-
(1999)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.442
, pp. 113-120
-
-
Aryal, P.1
Yoshikawa, K.2
Terashita, T.3
Guengerich, F.P.4
Shimada, T.5
Oda, Y.6
-
137
-
-
0035978747
-
Metabolic activation of heterocyclic amines and other procarcinogens in salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase
-
Oda, Y., Aryal, P., Terashita, T., Gillam, E. M. J., Guengerich, F. P., and Shimada, T. (2001) Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 492, 81-90.
-
(2001)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.492
, pp. 81-90
-
-
Oda, Y.1
Aryal, P.2
Terashita, T.3
Gillam, E.M.J.4
Guengerich, F.P.5
Shimada, T.6
-
138
-
-
77957352023
-
UvrB gene deletion enhances SOS chromotest sensitivity for nitroreductases that preferentially generate the 4-hydroxylamine metabolite of the anti-cancer prodrug CB1954
-
Prosser, G. A., and Patterson, A. V., and Ackerley, D. F. (2010) uvrB gene deletion enhances SOS chromotest sensitivity for nitroreductases that preferentially generate the 4-hydroxylamine metabolite of the anti-cancer prodrug CB1954. J. Biotechnol. 150, 190-194.
-
(2010)
J. Biotechnol.
, vol.150
, pp. 190-194
-
-
Prosser, G.A.1
Patterson, A.V.2
Ackerley, D.F.3
-
139
-
-
78449243843
-
Lux-biosensors for detection of SOS-response, heat shock, and oxidative stress
-
Kotova, V. Y., and Manukhov, I. V., and Zavilgelskii, G. B. (2010) Lux-biosensors for detection of SOS-response, heat shock, and oxidative stress. Appl. Biochem. Microbiol. 46, 781-788.
-
(2010)
Appl. Biochem. Microbiol.
, vol.46
, pp. 781-788
-
-
Kotova, V.Y.1
Manukhov, I.V.2
Zavilgelskii, G.B.3
-
140
-
-
84863232686
-
An E. Coli SOS-EGFP biosensor for fast and sensitive detection of DNA damaging agents
-
Chen, Z., Lu, M., Zou, D., and Wang, H. (2012) An E. coli SOS-EGFP biosensor for fast and sensitive detection of DNA damaging agents. J. Environ. Sci. 24, 541-549.
-
(2012)
J. Environ. Sci.
, vol.24
, pp. 541-549
-
-
Chen, Z.1
Lu, M.2
Zou, D.3
Wang, H.4
-
141
-
-
0036133084
-
Green fluorescent protein-based biosensor for detecting SOS-inducing activity of genotoxic compounds
-
Kostrzynska, M., and Leung, K. T., Lee, H., and Trevors, J. T. (2002) Green fluorescent protein-based biosensor for detecting SOS-inducing activity of genotoxic compounds. J. Microbiol. Methods 48, 43-51.
-
(2002)
J. Microbiol. Methods
, vol.48
, pp. 43-51
-
-
Kostrzynska, M.1
Leung, K.T.2
Lee, H.3
Trevors, J.T.4
-
142
-
-
84930796551
-
Toward a high-throughput screening platform for directed evolution of enzymes that activate genotoxic prodrugs
-
Copp, J. N., and Williams, E. M., Rich, M. H., Patterson, A. V., and Smaill, J. B., and Ackerley, D. F. (2014) Toward a high-throughput screening platform for directed evolution of enzymes that activate genotoxic prodrugs. Protein Eng., Des. Sel. 27, 399-403.
-
(2014)
Protein Eng., Des. Sel.
, vol.27
, pp. 399-403
-
-
Copp, J.N.1
Williams, E.M.2
Rich, M.H.3
Patterson, A.V.4
Smaill, J.B.5
Ackerley, D.F.6
-
143
-
-
84873734868
-
Construction and evaluation of two biosensors based on yeast transcriptional response to genotoxic chemicals
-
Wei, T., Zhang, C., Xu, X., Hanna, M., and Zhang, X. H., Wang, Y., Dai, H. P., and Xiao, W. (2013) Construction and evaluation of two biosensors based on yeast transcriptional response to genotoxic chemicals. Biosens. Bioelectron. 44, 138-145.
-
(2013)
Biosens. Bioelectron.
, vol.44
, pp. 138-145
-
-
Wei, T.1
Zhang, C.2
Xu, X.3
Hanna, M.4
Zhang, X.H.5
Wang, Y.6
Dai, H.P.7
Xiao, W.8
-
144
-
-
33746309471
-
High-speciticity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay
-
Hastwell, P. W., and Chai, L. L., Roberts, K. J., Webster, T. W., and Harvey, J. S., Rees, R. W., and Walmsley, R. M. (2006) High-speciticity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 607, 160-175.
-
(2006)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.607
, pp. 160-175
-
-
Hastwell, P.W.1
Chai, L.L.2
Roberts, K.J.3
Webster, T.W.4
Harvey, J.S.5
Rees, R.W.6
Walmsley, R.M.7
-
145
-
-
53249113140
-
A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals
-
Ohno, K., Ishihata, K., Tanaka-Azuma, Y., and Yamada, T. (2008) A genotoxicity test system based on p53R2 gene expression in human cells: Assessment of its reactivity to various classes of genotoxic chemicals. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 656, 27-35.
-
(2008)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.656
, pp. 27-35
-
-
Ohno, K.1
Ishihata, K.2
Tanaka-Azuma, Y.3
Yamada, T.4
-
146
-
-
74649086274
-
The development of RAD51C, cystatin A, p53 and nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development
-
Westerink, W. M. A., Stevenson, J. C. R., Horbach, G. J., and Schoonen, W. (2010) The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 696, 21-40.
-
(2010)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.696
, pp. 21-40
-
-
Westerink, W.M.A.1
Stevenson, J.C.R.2
Horbach, G.J.3
Schoonen, W.4
-
147
-
-
77950174369
-
Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression
-
Zager, V., Cemazar, M., Hreljac, I., Lah, T. T., Sersa, G., and Filipic, M. (2010) Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression. Radiol. Oncol. 44, 42-51.
-
(2010)
Radiol. Oncol.
, vol.44
, pp. 42-51
-
-
Zager, V.1
Cemazar, M.2
Hreljac, I.3
Lah, T.T.4
Sersa, G.5
Filipic, M.6
-
148
-
-
79954613640
-
Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment
-
Hendriks, G., Atallah, M., Raamsman, M., Morolli, B., van der Putten, H., Jaadar, H., Tijdens, I., Esveldt-van Lange, R., Mullenders, L., van de Water, B., and Vrieling, H. (2011) Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment. Mutat. Res., Fundam. Mol. Mech. Mutagen. 709-10, 49-59.
-
(2011)
Mutat. Res., Fundam. Mol. Mech. Mutagen.
, vol.709
, Issue.10
, pp. 49-59
-
-
Hendriks, G.1
Atallah, M.2
Raamsman, M.3
Morolli, B.4
Van Der Putten, H.5
Jaadar, H.6
Tijdens, I.7
Esveldt-Van Lange, R.8
Mullenders, L.9
Van De Water, B.10
Vrieling, H.11
-
149
-
-
84555188954
-
The ToxTracker assay: Novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals
-
Hendriks, G., Atallah, M., Morolli, B., Calleja, F., Ras-Verloop, N., Huijskens, I., Raamsman, M., van de Water, B., and Vrieling, H. (2012) The ToxTracker Assay: Novel GFP Reporter Systems that Provide Mechanistic Insight into the Genotoxic Properties of Chemicals. Toxicol. Sci. 125, 285-298.
-
(2012)
Toxicol. Sci.
, vol.125
, pp. 285-298
-
-
Hendriks, G.1
Atallah, M.2
Morolli, B.3
Calleja, F.4
Ras-Verloop, N.5
Huijskens, I.6
Raamsman, M.7
Van De Water, B.8
Vrieling, H.9
-
150
-
-
84869069268
-
Development of a high-throughput gaussia luciferase reporter assay for the activation of the GADD45a gene by mutagens, promutagens, clastogens, and aneugens
-
Hughes, C., Rabinowitz, A., Tate, M., Birrell, L., Allsup, J., Billinton, N., and Walmsley, R. M. (2012) Development of a High-Throughput Gaussia Luciferase Reporter Assay for the Activation of the GADD45a Gene by Mutagens, Promutagens, Clastogens, and Aneugens. J. Biomol. Screening 17, 1302-1315.
-
(2012)
J. Biomol. Screening
, vol.17
, pp. 1302-1315
-
-
Hughes, C.1
Rabinowitz, A.2
Tate, M.3
Birrell, L.4
Allsup, J.5
Billinton, N.6
Walmsley, R.M.7
-
151
-
-
84901311454
-
A cell-based biosensor system HepG2CDKN1A-dsred for rapid and simple detection of genotoxic agents
-
Blagus, T., Zager, V., Cemazar, M., Sersa, G., Kamensek, U., Zegura, B., Nunic, J., and Filipic, M. (2014) A cell-based biosensor system HepG2CDKN1A-DsRed for rapid and simple detection of genotoxic agents. Biosens. Bioelectron. 61, 102-111.
-
(2014)
Biosens. Bioelectron.
, vol.61
, pp. 102-111
-
-
Blagus, T.1
Zager, V.2
Cemazar, M.3
Sersa, G.4
Kamensek, U.5
Zegura, B.6
Nunic, J.7
Filipic, M.8
-
152
-
-
84901300409
-
Fluorescence-based recombination assay for sensitive and specific detection of genotoxic carcinogens in human cells
-
Ireno, I. C., Baumann, C., Stober, R., Hengstler, J. G., and Wiesmuller, L. (2014) Fluorescence-based recombination assay for sensitive and specific detection of genotoxic carcinogens in human cells. Arch. Toxicol. 88, 1141-1159.
-
(2014)
Arch. Toxicol.
, vol.88
, pp. 1141-1159
-
-
Ireno, I.C.1
Baumann, C.2
Stober, R.3
Hengstler, J.G.4
Wiesmuller, L.5
-
153
-
-
84895065935
-
Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress
-
van der Linden, S. C., von Bergh, A. R. M., van Vught-Lussenburg, B. M. A., Jonker, L. R. A., Teunis, M., Krul, C. A. M., and van der Burg, B. (2014) Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 760, 23-32.
-
(2014)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.760
, pp. 23-32
-
-
Van Der Linden, S.C.1
Von Bergh, A.R.M.2
Van Vught-Lussenburg, B.M.A.3
Jonker, L.R.A.4
Teunis, M.5
Krul, C.A.M.6
Van Der Burg, B.7
-
154
-
-
84963796193
-
The extended ToxTracker assay discriminates between induction of DNA damage, oxidative stress, and protein misfolding
-
Hendriks, G., and Derr, R. S., Misovic, B., Morolli, B., Calleja, F., and Vrieling, H. (2016) The Extended ToxTracker Assay Discriminates Between Induction of DNA Damage, Oxidative Stress, and Protein Misfolding. Toxicol. Sci. 150, 190-203.
-
(2016)
Toxicol. Sci.
, vol.150
, pp. 190-203
-
-
Hendriks, G.1
Derr, R.S.2
Misovic, B.3
Morolli, B.4
Calleja, F.5
Vrieling, H.6
-
155
-
-
84884702584
-
Evaluation of the GADD45 alpha-GFP GreenScreen HC assay for rapid and reliable in vitro early genotoxicity screening
-
Luzy, A. P., Orsini, N., Linget, J. M., and Bouvier, G. (2013) Evaluation of the GADD45 alpha-GFP GreenScreen HC assay for rapid and reliable in vitro early genotoxicity screening. J. Appl. Toxicol. 33, 1303-1315.
-
(2013)
J. Appl. Toxicol.
, vol.33
, pp. 1303-1315
-
-
Luzy, A.P.1
Orsini, N.2
Linget, J.M.3
Bouvier, G.4
-
156
-
-
85027688057
-
A comparative study into the high specificity of GreenScreen HC in relation to other in-vitro genotoxicity tests in the human lymphoblastoid cell line TK6
-
Topham, C., Hastwell, P., and Walmsley, R. (2007) A comparative study into the high specificity of GreenScreen HC in relation to other in-vitro genotoxicity tests in the human lymphoblastoid cell line TK6. Mutagenesis 22, 452-453.
-
(2007)
Mutagenesis
, vol.22
, pp. 452-453
-
-
Topham, C.1
Hastwell, P.2
Walmsley, R.3
-
157
-
-
49649106099
-
Interlaboratory assessment of the green-screen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method
-
Billinton, N., and Hastwell, P. W., Beerens, D., Birrell, L., Ellis, P., Maskell, S., Webster, T. W., Windebank, S., Woestenborghs, F., Lynch, A. M., Scott, A. D., Tweats, D. J., van Gompel, J., Rees, R. W., and Walmsley, R. M. (2008) Interlaboratory assessment of the Green-Screen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method. Mutat. Res., Genet. Toxicol. Environ. Mutagen. 653, 23-33.
-
(2008)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.653
, pp. 23-33
-
-
Billinton, N.1
Hastwell, P.W.2
Beerens, D.3
Birrell, L.4
Ellis, P.5
Maskell, S.6
Webster, T.W.7
Windebank, S.8
Woestenborghs, F.9
Lynch, A.M.10
Scott, A.D.11
Tweats, D.J.12
Van Gompel, J.13
Rees, R.W.14
Walmsley, R.M.15
-
158
-
-
85027719155
-
Incorporation of the GADD45-GFP greenscreen HC assay into pre-clinical drug development screening to reduce compound attrition
-
Hastwell, P. W., and Dilmamode, B. Z., Powney, B. L., Brown, A. J., and Harvey, J. S., Lynch, A. M., Rees, R. W., and Rees, S. (2009) Incorporation of the GADD45-GFP greenscreen HC assay into pre-clinical drug development screening to reduce compound attrition. Mutagenesis 24, 549-549.
-
(2009)
Mutagenesis
, vol.24
, pp. 549
-
-
Hastwell, P.W.1
Dilmamode, B.Z.2
Powney, B.L.3
Brown, A.J.4
Harvey, J.S.5
Lynch, A.M.6
Rees, R.W.7
Rees, S.8
-
159
-
-
70349512691
-
Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast (TM) chemicals
-
Knight, A. W., Little, S., Houck, K., Dix, D., Judson, R., Richard, A., McCarroll, N., Akerman, G., Yang, C. H., Birrell, L., and Walmsley, R. M. (2009) Evaluation of high-throughput genotoxicity assays used in profiling the US EPA ToxCast (TM) chemicals. Regul. Toxicol. Pharmacol. 55, 188-199.
-
(2009)
Regul. Toxicol. Pharmacol.
, vol.55
, pp. 188-199
-
-
Knight, A.W.1
Little, S.2
Houck, K.3
Dix, D.4
Judson, R.5
Richard, A.6
McCarroll, N.7
Akerman, G.8
Yang, C.H.9
Birrell, L.10
Walmsley, R.M.11
-
160
-
-
77953916495
-
A pre-validation transferability study of the green screen HC GADD45a-GFP assay with a metabolic activation system (S9)
-
Billinton, N., Bruce, S., Hansen, J. R., and Hastwell, P. W., Jagger, C., McComb, C., Klug, M. L., Pant, K., Rabinowitz, A., Rees, R., Tate, M., Vinggaard, A. M., and Walmsley, R. M. (2010) A pre-validation transferability study of the Green Screen HC GADD45a-GFP assay with a metabolic activation system (S9). Mutat. Res., Genet. Toxicol. Environ. Mutagen. 700, 44-50.
-
(2010)
Mutat. Res., Genet. Toxicol. Environ. Mutagen.
, vol.700
, pp. 44-50
-
-
Billinton, N.1
Bruce, S.2
Hansen, J.R.3
Hastwell, P.W.4
Jagger, C.5
McComb, C.6
Klug, M.L.7
Pant, K.8
Rabinowitz, A.9
Rees, R.10
Tate, M.11
Vinggaard, A.M.12
Walmsley, R.M.13
-
161
-
-
84876732445
-
Cellular-signaling pathways unveil the carcinogenic potential of chemicals
-
Hendriks, G., van de Water, B., Schoonen, W., and Vrieling, H. (2013) Cellular-signaling pathways unveil the carcinogenic potential of chemicals. J. Appl. Toxicol. 33, 399-409.
-
(2013)
J. Appl. Toxicol.
, vol.33
, pp. 399-409
-
-
Hendriks, G.1
Van De Water, B.2
Schoonen, W.3
Vrieling, H.4
-
162
-
-
84884179017
-
The adverse outcome pathway concept: A pragmatic tool in toxicology
-
Vinken, M. (2013) The adverse outcome pathway concept: A pragmatic tool in toxicology. Toxicology 312, 158-165.
-
(2013)
Toxicology
, vol.312
, pp. 158-165
-
-
Vinken, M.1
-
163
-
-
84883187061
-
A high content screening assay to predict human drug-induced liver injury during drug discovery
-
Persson, M., and Loye, A. F., Mow, T., and Hornberg, J. J. (2013) A high content screening assay to predict human drug-induced liver injury during drug discovery. J. Pharmacol. Toxicol. Methods 68, 302-313.
-
(2013)
J. Pharmacol. Toxicol. Methods
, vol.68
, pp. 302-313
-
-
Persson, M.1
Loye, A.F.2
Mow, T.3
Hornberg, J.J.4
-
164
-
-
84889586629
-
Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes
-
Garside, H., and Marcoe, K. F., Chesnut-Speelman, J., Foster, A. J., Muthas, D., and Kenna, J. G., Warrior, U., Bowes, J., and Baumgartner, J. 2014. Evaluation of the use of imaging parameters for the detection of compound-induced hepatotoxicity in 384-well cultures of HepG2 cells and cryopreserved primary human hepatocytes. Toxicol. In Vitro 28, 171-181.
-
(2014)
Toxicol. in Vitro
, vol.28
, pp. 171-181
-
-
Garside, H.1
Marcoe, K.F.2
Chesnut-Speelman, J.3
Foster, A.J.4
Muthas, D.5
Kenna, J.G.6
Warrior, U.7
Bowes, J.8
Baumgartner, J.9
-
165
-
-
84902106571
-
High-content analysis in toxicology: Screening substances for human toxicity potential, elucidating subcellular mechanisms and in vivo use as translational safety biomarkers
-
O'Brien, P. J. (2014) High-Content Analysis in Toxicology: Screening Substances for Human Toxicity Potential, Elucidating Subcellular Mechanisms and In Vivo Use as Translational Safety Biomarkers. Basic Clin. Pharmacol. Toxicol. 115, 4-17.
-
(2014)
Basic Clin. Pharmacol. Toxicol.
, vol.115
, pp. 4-17
-
-
O'Brien, P.J.1
-
166
-
-
49049092192
-
Uniform threshold intensity distribution-based quantitative multivariate imaging cytometry
-
Naoghare, P. K., and Kim, M. J., and Song, J. M. (2008) Uniform threshold intensity distribution-based quantitative multivariate imaging cytometry. Anal. Chem. 80, 5407-5417.
-
(2008)
Anal. Chem.
, vol.80
, pp. 5407-5417
-
-
Naoghare, P.K.1
Kim, M.J.2
Song, J.M.3
-
167
-
-
84936757411
-
Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses
-
Zhang, Q., Bhattacharya, S., Conolly, R. B., and Clewell, H. J., Kaminski, N. E., and Andersen, M. E. (2014) Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses. Environ. Health Perspect. 122, 1261-1270.
-
(2014)
Environ. Health Perspect.
, vol.122
, pp. 1261-1270
-
-
Zhang, Q.1
Bhattacharya, S.2
Conolly, R.B.3
Clewell, H.J.4
Kaminski, N.E.5
Andersen, M.E.6
-
168
-
-
84949575568
-
Synthetic biology for pharmaceutical drug discovery
-
Trosset, J. Y., and Carbonell, P. (2015) Synthetic biology for pharmaceutical drug discovery. Drug Des., Dev. Ther. 9, 6285-6302.
-
(2015)
Drug Des., Dev. Ther.
, vol.9
, pp. 6285-6302
-
-
Trosset, J.Y.1
Carbonell, P.2
-
169
-
-
34547916832
-
Environmental signal integration by a modular AND gate
-
Anderson, J. C., and Voigt, C. A., and Arkin, A. P. (2007) Environmental signal integration by a modular AND gate. Mol. Syst. Biol., Vol. 3, DOI: 10.1038/msb4100173.
-
(2007)
Mol. Syst. Biol.
, vol.3
-
-
Anderson, J.C.1
Voigt, C.A.2
Arkin, A.P.3
-
170
-
-
80054762005
-
Protein delivery using engineered viruslike particles
-
Kaczmarczyk, S. J., Sitaraman, K., Young, H. A., and Hughes, S. H., and Chatterjee, D. K. (2011) Protein delivery using engineered viruslike particles. Proc. Natl. Acad. Sci. U. S. A. 108, 16998-17003.
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 16998-17003
-
-
Kaczmarczyk, S.J.1
Sitaraman, K.2
Young, H.A.3
Hughes, S.H.4
Chatterjee, D.K.5
-
171
-
-
84926470511
-
Higher order assembly of virus-like particles (VLPs) mediated by multi-valent protein linkers
-
Uchida, M., LaFrance, B., Broomell, C. C., and Prevelige, P. E., and Douglas, T. (2015) Higher Order Assembly of Virus-like Particles (VLPs) Mediated by Multi-valent Protein Linkers. Small 11, 1562-1570.
-
(2015)
Small
, vol.11
, pp. 1562-1570
-
-
Uchida, M.1
LaFrance, B.2
Broomell, C.C.3
Prevelige, P.E.4
Douglas, T.5
-
172
-
-
79959514813
-
A synthetic optogenetic transcription device enhances blood-glucose homeostasis in mice
-
Ye, H. F., Daoud-El Baba, M., Peng, R. W., and Fussenegger, M. (2011) A Synthetic Optogenetic Transcription Device Enhances Blood-Glucose Homeostasis in Mice. Science 332, 1565-1568.
-
(2011)
Science
, vol.332
, pp. 1565-1568
-
-
Ye, H.F.1
Daoud-El Baba, M.2
Peng, R.W.3
Fussenegger, M.4
-
173
-
-
84872001455
-
Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome
-
Ye, H. F., Charpin-El Hamri, G., Zwicky, K., Christen, M., Folcher, M., and Fussenegger, M. (2013) Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome. Proc. Natl. Acad. Sci. U. S. A. 110, 141-146.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 141-146
-
-
Ye, H.F.1
Charpin-El Hamri, G.2
Zwicky, K.3
Christen, M.4
Folcher, M.5
Fussenegger, M.6
-
174
-
-
83855163433
-
Emerging biomedical applications of synthetic biology
-
Weber, W., and Fussenegger, M. (2012) Emerging biomedical applications of synthetic biology. Nat. Rev. Genet. 13, 21-35.
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 21-35
-
-
Weber, W.1
Fussenegger, M.2
-
175
-
-
80053495138
-
DNAMediated assembly of cytochrome P450 BM3 subdomains
-
Erkelenz, M., and Kuo, C. H., and Niemeyer, C. M. (2011) DNAMediated Assembly of Cytochrome P450 BM3 Subdomains. J. Am. Chem. Soc. 133, 16111-16118.
-
(2011)
J. Am. Chem. Soc.
, vol.133
, pp. 16111-16118
-
-
Erkelenz, M.1
Kuo, C.H.2
Niemeyer, C.M.3
-
176
-
-
84938293809
-
Sequence modifications and heterologous expression of eukaryotic cytochromes P450 in Escherichia coli
-
Ichinose, H., Hatakeyama, M., and Yamauchi, Y. (2015) Sequence modifications and heterologous expression of eukaryotic cytochromes P450 in Escherichia coli. J. Biosci. Bioeng. 120, 268-274.
-
(2015)
J. Biosci. Bioeng.
, vol.120
, pp. 268-274
-
-
Ichinose, H.1
Hatakeyama, M.2
Yamauchi, Y.3
-
177
-
-
84890178034
-
Advances in genetic circuit design: Novel biochemistries, deep part mining, and precision gene expression
-
Nielsen, A. A. K., Segall-Shapiro, T. H., and Voigt, C. A. (2013) Advances in genetic circuit design: novel biochemistries, deep part mining, and precision gene expression. Curr. Opin. Chem. Biol. 17, 878-892.
-
(2013)
Curr. Opin. Chem. Biol.
, vol.17
, pp. 878-892
-
-
Nielsen, A.A.K.1
Segall-Shapiro, T.H.2
Voigt, C.A.3
|