-
1
-
-
73049167504
-
General conclusions: Telenomic mechanisms in cellular metabolism, growth, and differentiation
-
Monod, J. & Jacob, F. General conclusions: telenomic mechanisms in cellular metabolism, growth, and differentiation. Cold Spring Harb. Symp. Quant. Biol. 26, 389-401 (1961).
-
(1961)
Cold Spring Harb. Symp. Quant. Biol.
, vol.26
, pp. 389-401
-
-
Monod, J.1
Jacob, F.2
-
2
-
-
0015609281
-
The logical analysis of continuous, non-linear biochemical control networks
-
Glass, L. & Kauffman, S. A. The logical analysis of continuous, non-linear biochemical control networks. J. Theor. Biol. 39, 103-129 (1973).
-
(1973)
J. Theor. Biol.
, vol.39
, pp. 103-129
-
-
Glass, L.1
Kauffman, S.A.2
-
3
-
-
0016145568
-
Comparison of classical and autogenous systems of regulation in inducible operons
-
Savageau, M. A. Comparison of classical and autogenous systems of regulation in inducible operons. Nature 252, 546-549 (1974).
-
(1974)
Nature
, vol.252
, pp. 546-549
-
-
Savageau, M.A.1
-
4
-
-
0015993618
-
The large scale structure and dynamics of gene control circuits: An ensemble approach
-
Kauffman, S. The large scale structure and dynamics of gene control circuits: an ensemble approach. J. Theor. Biol. 44, 167-190 (1974).
-
(1974)
J. Theor. Biol.
, vol.44
, pp. 167-190
-
-
Kauffman, S.1
-
5
-
-
0016758861
-
Classification of biological networks by their qualitative dynamics
-
Glass, L. Classification of biological networks by their qualitative dynamics. J. Theor. Biol. 54, 85-107 (1975).
-
(1975)
J. Theor. Biol.
, vol.54
, pp. 85-107
-
-
Glass, L.1
-
6
-
-
0034175821
-
Towards a circuit engineering discipline
-
McAdams, H. H. & Arkin, A. Towards a circuit engineering discipline. Curr. Biol. 10, R318-R320 (2000).
-
(2000)
Curr. Biol.
, vol.10
-
-
McAdams, H.H.1
Arkin, A.2
-
7
-
-
0029028963
-
Circuit simulation of genetic networks
-
McAdams, H. H. & Shapiro, L. Circuit simulation of genetic networks. Science 269, 650-656 (1995).
-
(1995)
Science
, vol.269
, pp. 650-656
-
-
McAdams, H.H.1
Shapiro, L.2
-
8
-
-
0034688174
-
Construction of a genetic toggle switch in Escherichia coli
-
DOI 10.1038/35002131
-
Gardner, T. S., Cantor, C. R. & Collins, J. J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000). (Pubitemid 30062394)
-
(2000)
Nature
, vol.403
, Issue.6767
, pp. 339-342
-
-
Gardner, T.S.1
Cantor, C.R.2
Collins, J.J.3
-
9
-
-
0034688173
-
A synthetic oscillatory network of transcriptional regulators
-
Elowitz, M. B. & Leibler, S. A synthetic oscillatory network of transcriptional regulators. Nature 403, 335-338 (2000).
-
(2000)
Nature
, vol.403
, pp. 335-338
-
-
Elowitz, M.B.1
Leibler, S.2
-
10
-
-
0038241770
-
Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli
-
Atkinson, M. R., Savageau, M. A., Myers, J. T. & Ninfa, A. J. Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli. Cell 11 3, 597-607 (2003).
-
(2003)
Cell
, vol.11
, Issue.3
, pp. 597-607
-
-
Atkinson, M.R.1
Savageau, M.A.2
Myers, J.T.3
Ninfa, A.J.4
-
11
-
-
21444457242
-
Programmable ligand-controlled riboregulators of eukaryotic gene expression
-
DOI 10.1038/nbt1069
-
Bayer, T. S. & Smolke, C. D. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nature Biotech. 23, 337-343 (2005). (Pubitemid 41094422)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.3
, pp. 337-343
-
-
Bayer, T.S.1
Smolke, C.D.2
-
12
-
-
34447505900
-
A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells
-
Deans, T. L., Cantor, C. R. & Collins, J. J. A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell 130, 363-372 (2007).
-
(2007)
Cell
, vol.130
, pp. 363-372
-
-
Deans, T.L.1
Cantor, C.R.2
Collins, J.J.3
-
13
-
-
0141757323
-
Reprogramming control of an allosteric signaling switch through modular recombination
-
DOI 10.1126/science.1085945
-
Dueber, J. E., Yeh, B. J., Chak, K. & Lim, W. A. Reprogramming control of an allosteric signaling switch through modular recombination. Science 301, 1904-1908 (2003). (Pubitemid 37221395)
-
(2003)
Science
, vol.301
, Issue.5641
, pp. 1904-1908
-
-
Dueber, J.E.1
Yeh, B.J.2
Chak, K.3
Lim, W.A.4
-
14
-
-
66349125024
-
Synthetic gene networks that count
-
Friedland, A. E. et al. Synthetic gene networks that count. Science 324, 1199-1202 (2009).
-
(2009)
Science
, vol.324
, pp. 1199-1202
-
-
Friedland, A.E.1
-
15
-
-
33646565046
-
A tightly regulated inducible expression system utilizing the fim inversion recombination switch
-
Ham, T. S., Lee, S. K., Keasling, J. D. & Arkin, A. P. A tightly regulated inducible expression system utilizing the fim inversion recombination switch. Biotechnol. Bioeng. 94, 1-4 (2006).
-
(2006)
Biotechnol. Bioeng.
, vol.94
, pp. 1-4
-
-
Ham, T.S.1
Lee, S.K.2
Keasling, J.D.3
Arkin, A.P.4
-
16
-
-
50949122967
-
Design and construction of a double inversion recombination switch for heritable sequential genetic memory
-
Ham, T. S., Lee, S. K., Keasling, J. D. & Arkin, A. P. Design and construction of a double inversion recombination switch for heritable sequential genetic memory. PLoS ONE 3, e2815 (2008).
-
(2008)
PLoS ONE
, vol.3
-
-
Ham, T.S.1
Lee, S.K.2
Keasling, J.D.3
Arkin, A.P.4
-
18
-
-
3042822415
-
An engineered epigenetic transgene switch in mammalian cells
-
DOI 10.1038/nbt980
-
Kramer, B. P. et al. An engineered epigenetic transgene switch in mammalian cells. Nature Biotech. 22, 867-870 (2004). (Pubitemid 38886606)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.7
, pp. 867-870
-
-
Kramer, B.P.1
Viretta, A.U.2
Baba, M.D.-E.3
Aubel, D.4
Weber, W.5
Fussenegger, M.6
-
19
-
-
34548856538
-
Rational design of memory in eukaryotic cells
-
Ajo-Franklin, C. M. et al. Rational design of memory in eukaryotic cells. Genes Dev. 21, 2271-2276 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 2271-2276
-
-
Ajo-Franklin, C.M.1
-
20
-
-
18344381476
-
A synthetic gene-metabolic oscillator
-
DOI 10.1038/nature03508
-
Fung, E. et al. A synthetic gene-metabolic oscillator. Nature 435, 118-122 (2005). (Pubitemid 40655919)
-
(2005)
Nature
, vol.435
, Issue.7038
, pp. 118-122
-
-
Fung, E.1
Wong, W.W.2
Suen, J.K.3
Bulter, T.4
Lee, S.-G.5
Liao, J.C.6
-
21
-
-
57049159362
-
A fast, robust and tunable synthetic gene oscillator
-
DOI 10.1038/nature07389, PII NATURE07389
-
Stricker, J. et al. A fast, robust and tunable synthetic gene oscillator. Nature 456, 516-519 (2008). (Pubitemid 352759003)
-
(2008)
Nature
, vol.456
, Issue.7221
, pp. 516-519
-
-
Stricker, J.1
Cookson, S.2
Bennett, M.R.3
Mather, W.H.4
Tsimring, L.S.5
Hasty, J.6
-
22
-
-
58249117722
-
A tunable synthetic mammalian oscillator
-
Tigges, M., Marquez-Lago, T. T., Stelling, J. & Fussenegger, M. A tunable synthetic mammalian oscillator. Nature 457, 309-312 (2009).
-
(2009)
Nature
, vol.457
, pp. 309-312
-
-
Tigges, M.1
Marquez-Lago, T.T.2
Stelling, J.3
Fussenegger, M.4
-
23
-
-
75149191906
-
A synchronized quorum of genetic clocks
-
Danino, T., Mondragon-Palomino, O., Tsimring, L. & Hasty, J. A synchronized quorum of genetic clocks. Nature 463, 326-330 (2010).
-
(2010)
Nature
, vol.463
, pp. 326-330
-
-
Danino, T.1
Mondragon-Palomino, O.2
Tsimring, L.3
Hasty, J.4
-
24
-
-
2342578714
-
Spatiotemporal control of gene expression with pulse-generating networks
-
DOI 10.1073/pnas.0307571101
-
Basu, S., Mehreja, R., Thiberge, S., Chen, M. T. & Weiss, R. Spatiotemporal control of gene expression with pulse-generating networks. Proc. Natl Acad. Sci. USA 101, 6355-6360 (2004). (Pubitemid 38585978)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6355-6360
-
-
Basu, S.1
Mehreja, R.2
Thiberge, S.3
Chen, M.-T.4
Weiss, R.5
-
25
-
-
34547916832
-
Environmental signal integration by a modular and gate
-
Anderson, J. C., Voigt, C. A. & Arkin, A. P. Environmental signal integration by a modular AND gate. Mol. Syst. Biol. 3, 133 (2007).
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 133
-
-
Anderson, J.C.1
Voigt, C.A.2
Arkin, A.P.3
-
26
-
-
0037165942
-
Combinatorial synthesis of genetic networks
-
DOI 10.1126/science.1067407
-
Guet, C. C., Elowitz, M. B., Hsing, W. & Leibler, S. Combinatorial synthesis of genetic networks. Science 296, 1466-1470 (2002). (Pubitemid 34553091)
-
(2002)
Science
, vol.296
, Issue.5572
, pp. 1466-1470
-
-
Guet, C.C.1
Elowitz, M.B.2
Hsing, W.3
Leibler, S.4
-
27
-
-
29344453148
-
Cellular logic with orthogonal ribosomes
-
DOI 10.1021/ja055338d
-
Rackham, O. & Chin, J. W. Cellular logic with orthogonal ribosomes. J. Am. Chem. Soc. 127, 17584-17585 (2005). (Pubitemid 43003356)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.50
, pp. 17584-17585
-
-
Rackham, O.1
Chin, J.W.2
-
28
-
-
34447310821
-
A universal RNAi-based logic evaluator that operates in mammalian cells
-
DOI 10.1038/nbt1307, PII NBT1307
-
Rinaudo, K. et al. A universal RNAi-based logic evaluator that operates in mammalian cells. Nature Biotech. 25, 795-801 (2007). (Pubitemid 47052185)
-
(2007)
Nature Biotechnology
, vol.25
, Issue.7
, pp. 795-801
-
-
Rinaudo, K.1
Bleris, L.2
Maddamsetti, R.3
Subramanian, S.4
Weiss, R.5
Benenson, Y.6
-
29
-
-
0042360338
-
A deoxyribozyme-based molecular automaton
-
DOI 10.1038/nbt862
-
Stojanovic, M. N. & Stefanovic, D. A deoxyribozyme-based molecular automaton. Nature Biotech. 21, 1069-1074 (2003). (Pubitemid 37064737)
-
(2003)
Nature Biotechnology
, vol.21
, Issue.9
, pp. 1069-1074
-
-
Stojanovic, M.N.1
Stefanovic, D.2
-
30
-
-
54249113318
-
Higher-order cellular information processing with synthetic RNA devices
-
Win, M. N. & Smolke, C. D. Higher-order cellular information processing with synthetic RNA devices. Science 322, 456-460 (2008).
-
(2008)
Science
, vol.322
, pp. 456-460
-
-
Win, M.N.1
Smolke, C.D.2
-
31
-
-
17844374314
-
A synthetic multicellular system for programmed pattern formation
-
DOI 10.1038/nature03461
-
Basu, S., Gerchman, Y., Collins, C. H., Arnold, F. H. & Weiss, R. A synthetic multicellular system for programmed pattern formation. Nature 434, 1130-1134 (2005). (Pubitemid 40663491)
-
(2005)
Nature
, vol.434
, Issue.7037
, pp. 1130-1134
-
-
Basu, S.1
Gerchman, Y.2
Collins, C.H.3
Arnold, F.H.4
Weiss, R.5
-
32
-
-
14844358192
-
Ultrasensitivity and noise propagation in a synthetic transcriptional cascade
-
DOI 10.1073/pnas.0408507102
-
Hooshangi, S., Thiberge, S. & Weiss, R. Ultrasensitivity and noise propagation in a synthetic transcriptional cascade. Proc. Natl Acad. Sci. USA 102, 3581-3586 (2005). (Pubitemid 40354655)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.10
, pp. 3581-3586
-
-
Hooshangi, S.1
Thiberge, S.2
Weiss, R.3
-
33
-
-
67649840194
-
An externally tunable bacterial band-pass filter
-
Sohka, T. et al. An externally tunable bacterial band-pass filter. Proc. Natl Acad. Sci. USA 106, 10135-10140 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 10135-10140
-
-
Sohka, T.1
-
34
-
-
2942614884
-
Programmable cells: Interfacing natural and engineered gene networks
-
DOI 10.1073/pnas.0402940101
-
Kobayashi, H. et al. Programmable cells: interfacing natural and engineered gene networks. Proc. Natl Acad. Sci. USA 101, 8414-8419 (2004). (Pubitemid 38736589)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.22
, pp. 8414-8419
-
-
Kobayashi, H.1
Kaern, M.2
Araki, M.3
Chung, K.4
Gardner, T.S.5
Cantor, C.R.6
Collins, J.J.7
-
35
-
-
1942467023
-
Programmed population control by cell-cell communication and regulated killing
-
You, L., Cox, R. S., Weiss, R. & Arnold, F. H. Programmed population control by cell-cell communication and regulated killing. Nature 428, 868-871 (2004).
-
(2004)
Nature
, vol.428
, pp. 868-871
-
-
You, L.1
Cox, R.S.2
Weiss, R.3
Arnold, F.H.4
-
36
-
-
70450223309
-
Synthetic biology: Understanding biological design from synthetic circuits
-
Mukherji, S. & van Oudenaarden, A. Synthetic biology: understanding biological design from synthetic circuits. Nature Rev. Genet. 10, 859-871 (2009).
-
(2009)
Nature Rev. Genet.
, vol.10
, pp. 859-871
-
-
Mukherji, S.1
Van Oudenaarden, A.2
-
37
-
-
0023645007
-
Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells
-
Brown, M. et al. Lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell 49, 603-612 (1987).
-
(1987)
Cell
, vol.49
, pp. 603-612
-
-
Brown, M.1
-
38
-
-
0024405257
-
Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor
-
Deuschle, U. et al. Regulated expression of foreign genes in mammalian cells under the control of coliphage T3 RNA polymerase and lac repressor. Proc. Natl Acad. Sci. USA 86, 5400-5404 (1989).
-
(1989)
Proc. Natl Acad. Sci. USA
, vol.86
, pp. 5400-5404
-
-
Deuschle, U.1
-
39
-
-
0023666091
-
The inducible lac operator-repressor system is functional in mammalian cells
-
Hu, M. C. & Davidson, N. The inducible lac operator-repressor system is functional in mammalian cells. Cell 48, 555-566 (1987).
-
(1987)
Cell
, vol.48
, pp. 555-566
-
-
Hu, M.C.1
Davidson, N.2
-
41
-
-
0033767759
-
Streptogramin-based gene regulation systems for mammalian cells
-
Fussenegger, M. et al. Streptogramin-based gene regulation systems for mammalian cells. Nature Biotech. 18, 1203-1208 (2000).
-
(2000)
Nature Biotech.
, vol.18
, pp. 1203-1208
-
-
Fussenegger, M.1
-
42
-
-
0026720075
-
Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
-
Gossen, M. & Bujard, H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl Acad. Sci. USA 89, 5547-5551 (1992).
-
(1992)
Proc. Natl Acad. Sci. USA
, vol.89
, pp. 5547-5551
-
-
Gossen, M.1
Bujard, H.2
-
43
-
-
0036714926
-
Macrolide-based transgene control in mammalian cells and mice
-
Weber, W. et al. Macrolide-based transgene control in mammalian cells and mice. Nature Biotech. 20, 901-907 (2002).
-
(2002)
Nature Biotech.
, vol.20
, pp. 901-907
-
-
Weber, W.1
-
44
-
-
0037298235
-
A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR
-
Neddermann, P. et al. A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR. EMBO Rep. 4, 159-165 (2003).
-
(2003)
EMBO Rep.
, vol.4
, pp. 159-165
-
-
Neddermann, P.1
-
45
-
-
0242348870
-
Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice
-
Weber, W. et al. Streptomyces-derived quorum-sensing systems engineered for adjustable transgene expression in mammalian cells and mice. Nucleic Acids Res. 31, e71 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Weber, W.1
-
46
-
-
26444488248
-
A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1
-
Malphettes, L. et al. A novel mammalian expression system derived from components coordinating nicotine degradation in arthrobacter nicotinovorans pAO1. Nucleic Acids Res. 33, e107 (2005).
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Malphettes, L.1
-
47
-
-
33751268632
-
The cumate gene-switch: A system for regulated expression in mammalian cells
-
Mullick, A. et al. The cumate gene-switch: a system for regulated expression in mammalian cells. BMC Biotechnol. 6, 43 (2006).
-
(2006)
BMC Biotechnol.
, vol.6
, pp. 43
-
-
Mullick, A.1
-
48
-
-
33646100778
-
A genetic redox sensor for mammalian cells
-
Weber, W., Link, N. & Fussenegger, M. A genetic redox sensor for mammalian cells. Metab. Eng. 8, 273-280 (2006).
-
(2006)
Metab. Eng.
, vol.8
, pp. 273-280
-
-
Weber, W.1
Link, N.2
Fussenegger, M.3
-
49
-
-
8344248749
-
Gas-inducible transgene expression in mammalian cells and mice
-
DOI 10.1038/nbt1021
-
Weber, W. et al. Gas-inducible transgene expression in mammalian cells and mice. Nature Biotech. 22, 1440-1444 (2004). (Pubitemid 39482865)
-
(2004)
Nature Biotechnology
, vol.22
, Issue.11
, pp. 1440-1444
-
-
Weber, W.1
Rimann, M.2
Spielmann, M.3
Keller, B.4
Daoud-El Baba, M.5
Aubel, D.6
Weber, C.C.7
Fussenegger, M.8
-
50
-
-
0034006644
-
A temperature-regulated replicon-based DNA expression system
-
Boorsma, M. et al. A temperature-regulated replicon-based DNA expression system. Nature Biotech. 18, 429-432 (2000).
-
(2000)
Nature Biotech.
, vol.18
, pp. 429-432
-
-
Boorsma, M.1
-
51
-
-
0038239238
-
Conditional human VEGF-mediated vascularization in chicken embryos using a novel temperature-inducible gene regulation (TIGR) system
-
Weber, W. et al. Conditional human VEGF-mediated vascularization in chicken embryos using a novel temperature-inducible gene regulation (TIGR) system. Nucleic Acids Res. 31, e69 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
-
-
Weber, W.1
-
52
-
-
62549134078
-
A synthetic mammalian electro-genetic transcription circuit
-
Weber, W. et al. A synthetic mammalian electro-genetic transcription circuit. Nucleic Acids Res. 37, e33 (2009).
-
(2009)
Nucleic Acids Res.
, vol.37
-
-
Weber, W.1
-
53
-
-
0035656688
-
Non-coding RNA genes and the modern RNA world
-
Eddy, S. R. Non-coding RNA genes and the modern RNA world. Nature Rev. Genet. 2, 919-929 (2001).
-
(2001)
Nature Rev. Genet.
, vol.2
, pp. 919-929
-
-
Eddy, S.R.1
-
54
-
-
0037062949
-
The chemical repertoire of natural ribozymes
-
Doudna, J. A. & Cech, T. R. The chemical repertoire of natural ribozymes. Nature 418, 222-228 (2002).
-
(2002)
Nature
, vol.418
, pp. 222-228
-
-
Doudna, J.A.1
Cech, T.R.2
-
55
-
-
0021013526
-
The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme
-
Guerrier-Takada, C., Gardiner, K., Marsh, T., Pace, N. & Altman, S. The RNA moiety of ribonuclease P is the catalytic subunit of the enzyme. Cell 35, 849-857 (1983).
-
(1983)
Cell
, vol.35
, pp. 849-857
-
-
Guerrier-Takada, C.1
Gardiner, K.2
Marsh, T.3
Pace, N.4
Altman, S.5
-
56
-
-
0020417286
-
Self-splicing RNA: Autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena
-
Kruger, K. et al. Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. Cell 31, 147-157 (1982).
-
(1982)
Cell
, vol.31
, pp. 147-157
-
-
Kruger, K.1
-
57
-
-
0027751663
-
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
-
Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
-
(1993)
Cell
, vol.75
, pp. 843-854
-
-
Lee, R.C.1
Feinbaum, R.L.2
Ambros, V.3
-
58
-
-
0346070776
-
RNAs involved in copy-number control and incompatibility of plasmid R1
-
Stougaard, P., Molin, S. & Nordstrom, K. RNAs involved in copy-number control and incompatibility of plasmid R1. Proc. Natl Acad. Sci. USA 78, 6008-6012 (1981).
-
(1981)
Proc. Natl Acad. Sci. USA
, vol.78
, pp. 6008-6012
-
-
Stougaard, P.1
Molin, S.2
Nordstrom, K.3
-
59
-
-
85041131924
-
Antisense RNA control in bacteria, phages, and plasmids
-
Wagner, E. G. H. & Simons, R. W. Antisense RNA control in bacteria, phages, and plasmids. Annu. Rev. Microbiol. 48, 713-742 (1994).
-
(1994)
Annu. Rev. Microbiol.
, vol.48
, pp. 713-742
-
-
Wagner, E.G.H.1
Simons, R.W.2
-
60
-
-
33646582649
-
RNA synthetic biology
-
Isaacs, F. J., Dwyer, D. J. & Collins, J. J. RNA synthetic biology. Nature Biotech. 24, 545-554 (2006).
-
(2006)
Nature Biotech.
, vol.24
, pp. 545-554
-
-
Isaacs, F.J.1
Dwyer, D.J.2
Collins, J.J.3
-
61
-
-
0033230755
-
A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes
-
Gelfand, M. S., Mironov, A. A., Jomantas, J., Kozlov, Y. I. & Perumov, D. A. A conserved RNA structure element involved in the regulation of bacterial riboflavin synthesis genes. Trends Genet. 15, 439-442 (1999).
-
(1999)
Trends Genet.
, vol.15
, pp. 439-442
-
-
Gelfand, M.S.1
Mironov, A.A.2
Jomantas, J.3
Kozlov, Y.I.4
Perumov, D.A.5
-
62
-
-
0037031594
-
An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes
-
Johansson, J. et al. An RNA thermosensor controls expression of virulence genes in Listeria monocytogenes. Cell 110, 551-561 (2002).
-
(2002)
Cell
, vol.110
, pp. 551-561
-
-
Johansson, J.1
-
63
-
-
0034730125
-
A trans-acting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structures
-
Lease, R. A. & Belfort, M. A trans-acting RNA as a control switch in Escherichia coli: DsrA modulates function by forming alternative structures. Proc. Natl Acad. Sci. USA 97, 9919-9924 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 9919-9924
-
-
Lease, R.A.1
Belfort, M.2
-
64
-
-
0036437019
-
And mode of action of the second small RNA activator of RpoS translation
-
Majdalani, N., Hernandez, D. & Gottesman, S. Regulation and mode of action of the second small RNA activator of RpoS translation, RprA. Mol. Microbiol. 46, 813-826 (2002).
-
(2002)
RprA. Mol. Microbiol.
, vol.46
, pp. 813-826
-
-
Majdalani, N.1
Hernandez, D.2
Regulation, G.S.3
-
65
-
-
0038210214
-
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria
-
Mandal, M., Boese, B., Barrick, J. E., Winkler, W. C. & Breaker, R. R. Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. Cell 11 3, 577-586 (2003).
-
(2003)
Cell
, vol.11
, Issue.3
, pp. 577-586
-
-
Mandal, M.1
Boese, B.2
Barrick, J.E.3
Winkler, W.C.4
Breaker, R.R.5
-
66
-
-
18744396047
-
Sensing small molecules by nascent RNA: A mechanism to control transcription in bacteria
-
Mironov, A. S. et al. Sensing small molecules by nascent RNA: a mechanism to control transcription in bacteria. Cell 111, 747-756 (2002).
-
(2002)
Cell
, vol.111
, pp. 747-756
-
-
Mironov, A.S.1
-
67
-
-
0001641104
-
32: Evidence for a built-in RNA thermosensor
-
32: evidence for a built-in RNA thermosensor. Genes Dev. 13, 655-665 (1999).
-
(1999)
Genes Dev.
, vol.13
, pp. 655-665
-
-
Morita, M.T.1
-
68
-
-
0037206833
-
Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
-
Winkler, W., Nahvi, A. & Breaker, R. R. Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature 419, 952-956 (2002).
-
(2002)
Nature
, vol.419
, pp. 952-956
-
-
Winkler, W.1
Nahvi, A.2
Breaker, R.R.3
-
69
-
-
1642586299
-
Control of gene expression by a natural metabolite-responsive ribozyme
-
Winkler, W. C., Nahvi, A., Roth, A., Collins, J. A. & Breaker, R. R. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 428, 281-286 (2004).
-
(2004)
Nature
, vol.428
, pp. 281-286
-
-
Winkler, W.C.1
Nahvi, A.2
Roth, A.3
Collins, J.A.4
Breaker, R.R.5
-
70
-
-
27144527479
-
Regulation of bacterial gene expression by riboswitches
-
Winkler, W. C. & Breaker, R. R. Regulation of bacterial gene expression by riboswitches. Annu. Rev. Microbiol. 59, 487-517 (2005).
-
(2005)
Annu. Rev. Microbiol.
, vol.59
, pp. 487-517
-
-
Winkler, W.C.1
Breaker, R.R.2
-
71
-
-
0038275920
-
Translation repression by antisense sequences
-
Good, L. Translation repression by antisense sequences. Cell. Mol. Life Sci. 60, 854-861 (2003).
-
(2003)
Cell. Mol. Life Sci.
, vol.60
, pp. 854-861
-
-
Good, L.1
-
72
-
-
0037107776
-
Automated selection of aptamers against protein targets translated in vitro: From gene to aptamer
-
Cox, J. C. et al. Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer. Nucleic Acids Res. 30, e108 (2002).
-
(2002)
Nucleic Acids Res.
, vol.30
-
-
Cox, J.C.1
-
73
-
-
0025074907
-
In vitro selection of RNA molecules that bind specific ligands
-
Ellington, A. D. & Szostak, J. W. In vitro selection of RNA molecules that bind specific ligands. Nature 346, 818-822 (1990).
-
(1990)
Nature
, vol.346
, pp. 818-822
-
-
Ellington, A.D.1
Szostak, J.W.2
-
74
-
-
0034603154
-
Adaptive recognition by nucleic acid aptamers
-
Hermann, T. & Patel, D. J. Adaptive recognition by nucleic acid aptamers. Science 287, 820-825 (2000).
-
(2000)
Science
, vol.287
, pp. 820-825
-
-
Hermann, T.1
Patel, D.J.2
-
75
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk, C. & Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase. Science 249, 505-510 (1990).
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
76
-
-
4644275337
-
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage
-
Yen, L. et al. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature 431, 471-476 (2004).
-
(2004)
Nature
, vol.431
, pp. 471-476
-
-
Yen, L.1
-
77
-
-
0038752617
-
Computational design of receptor and sensor proteins with novel functions
-
Looger, L. L., Dwyer, M. A., Smith, J. J. & Hellinga, H. W. Computational design of receptor and sensor proteins with novel functions. Nature 423, 185-190 (2003).
-
(2003)
Nature
, vol.423
, pp. 185-190
-
-
Looger, L.L.1
Dwyer, M.A.2
Smith, J.J.3
Hellinga, H.W.4
-
78
-
-
44649153450
-
Rewiring the specificity of two-component signal transduction systems
-
Skerker, J. M. et al. Rewiring the specificity of two-component signal transduction systems. Cell 133, 1043-1054 (2008).
-
(2008)
Cell
, vol.133
, pp. 1043-1054
-
-
Skerker, J.M.1
-
79
-
-
40849100220
-
Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics
-
Bashor, C. J., Helman, N. C., Yan, S. & Lim, W. A. Using engineered scaffold interactions to reshape MAP kinase pathway signaling dynamics. Science 319, 1539-1543 (2008).
-
(2008)
Science
, vol.319
, pp. 1539-1543
-
-
Bashor, C.J.1
Helman, N.C.2
Yan, S.3
Lim, W.A.4
-
80
-
-
28544442417
-
Synthetic biology: Engineering Escherichia coli to see light
-
Levskaya, A. et al. Synthetic biology: engineering Escherichia coli to see light. Nature 438, 441-442 (2005).
-
(2005)
Nature
, vol.438
, pp. 441-442
-
-
Levskaya, A.1
-
81
-
-
70350070364
-
Spatiotemporal control of cell signalling using a light-switchable protein interaction
-
Levskaya, A., Weiner, O. D., Lim, W. A. & Voigt, C. A. Spatiotemporal control of cell signalling using a light-switchable protein interaction. Nature 461, 997-1001 (2009).
-
(2009)
Nature
, vol.461
, pp. 997-1001
-
-
Levskaya, A.1
Weiner, O.D.2
Lim, W.A.3
Voigt, C.A.4
-
82
-
-
67549145283
-
A synthetic genetic edge detection program
-
Tabor, J. J. et al. A synthetic genetic edge detection program. Cell 137, 1272-1281 (2009).
-
(2009)
Cell
, vol.137
, pp. 1272-1281
-
-
Tabor, J.J.1
-
83
-
-
34548447567
-
Mutations of the Igβ gene cause agammaglobulinemia in man
-
Ferrari, S. et al. Mutations of the Igβ gene cause agammaglobulinemia in man. J. Exp. Med. 204, 2047-2051 (2007).
-
(2007)
J. Exp. Med.
, vol.204
, pp. 2047-2051
-
-
Ferrari, S.1
-
84
-
-
58149398620
-
Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice
-
Becker, M. M. et al. Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice. Proc. Natl Acad. Sci. USA 105, 19944-19949 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 19944-19949
-
-
Becker, M.M.1
-
85
-
-
26444490055
-
Characterization of the reconstructed 1918 Spanish influenza pandemic virus
-
Tumpey, T. M. et al. Characterization of the reconstructed 1918 Spanish influenza pandemic virus. Science 310, 77-80 (2005).
-
(2005)
Science
, vol.310
, pp. 77-80
-
-
Tumpey, T.M.1
-
86
-
-
3042741121
-
Engineered riboregulators enable post-transcriptional control of gene expression
-
Isaacs, F. J. et al. Engineered riboregulators enable post-transcriptional control of gene expression. Nature Biotech. 22, 841-847 (2004).
-
(2004)
Nature Biotech.
, vol.22
, pp. 841-847
-
-
Isaacs, F.J.1
-
87
-
-
33947247352
-
Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli
-
Dwyer, D. J., Kohanski, M. A., Hayete, B. & Collins, J. J. Gyrase inhibitors induce an oxidative damage cellular death pathway in Escherichia coli. Mol. Syst. Biol. 3, 91 (2007).
-
(2007)
Mol. Syst. Biol.
, vol.3
, pp. 91
-
-
Dwyer, D.J.1
Kohanski, M.A.2
Hayete, B.3
Collins, J.J.4
-
88
-
-
34548213103
-
A common mechanism of cellular death induced by bactericidal antibiotics
-
Kohanski, M. A., Dwyer, D. J., Hayete, B., Lawrence, C. A. & Collins, J. J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130, 797-810 (2007).
-
(2007)
Cell
, vol.130
, pp. 797-810
-
-
Kohanski, M.A.1
Dwyer, D.J.2
Hayete, B.3
Lawrence, C.A.4
Collins, J.J.5
-
89
-
-
55449126342
-
Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death
-
Kohanski, M. A., Dwyer, D. J., Wierzbowski, J., Cottarel, G. & Collins, J. J. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death. Cell 135, 679-690 (2008).
-
(2008)
Cell
, vol.135
, pp. 679-690
-
-
Kohanski, M.A.1
Dwyer, D.J.2
Wierzbowski, J.3
Cottarel, G.4
Collins, J.J.5
-
90
-
-
48249141397
-
A synthetic mammalian gene circuit reveals antituberculosis compounds
-
Weber, W. et al. A synthetic mammalian gene circuit reveals antituberculosis compounds. Proc. Natl Acad. Sci. USA 105, 9994-9998 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 9994-9998
-
-
Weber, W.1
-
91
-
-
34547448587
-
Dispersing biofilms with engineered enzymatic bacteriophage
-
Lu, T. K. & Collins, J. J. Dispersing biofilms with engineered enzymatic bacteriophage. Proc. Natl Acad. Sci. USA 104, 11197-11202 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 11197-11202
-
-
Lu, T.K.1
Collins, J.J.2
-
92
-
-
63849290890
-
Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy
-
Lu, T. K. & Collins, J. J. Engineered bacteriophage targeting gene networks as adjuvants for antibiotic therapy. Proc. Natl Acad. Sci. USA 106, 4629-4634 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4629-4634
-
-
Lu, T.K.1
Collins, J.J.2
-
93
-
-
0034759057
-
Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy
-
Ramachandra, M. et al. Re-engineering adenovirus regulatory pathways to enhance oncolytic specificity and efficacy. Nature Biotech. 19, 1035-1041 (2001).
-
(2001)
Nature Biotech.
, vol.19
, pp. 1035-1041
-
-
Ramachandra, M.1
-
94
-
-
29144482539
-
Environmentally controlled invasion of cancer cells by engineered bacteria
-
Anderson, J. C., Clarke, E. J., Arkin, A. P. & Voigt, C. A. Environmentally controlled invasion of cancer cells by engineered bacteria. J. Mol. Biol. 355, 619-627 (2006).
-
(2006)
J. Mol. Biol.
, vol.355
, pp. 619-627
-
-
Anderson, J.C.1
Clarke, E.J.2
Arkin, A.P.3
Voigt, C.A.4
-
95
-
-
69949126005
-
Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
-
Stavreva, D. A. et al. Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nature Cell Biol. 11, 1093-1102 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 1093-1102
-
-
Stavreva, D.A.1
-
96
-
-
33847302013
-
A synthetic time-delay circuit in mammalian cells and mice
-
DOI 10.1073/pnas.0606398104
-
Weber, W. et al. A synthetic time-delay circuit in mammalian cells and mice. Proc. Natl Acad. Sci. USA 104, 2643-2648 (2007). (Pubitemid 46327933)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.8
, pp. 2643-2648
-
-
Weber, W.1
Stelling, J.2
Rimann, M.3
Keller, B.4
Daoud-El Baba, M.5
Weber, C.C.6
Aubel, D.7
Fussenegger, M.8
-
97
-
-
66049143446
-
Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt
-
Dean, J. T. et al. Resistance to diet-induced obesity in mice with synthetic glyoxylate shunt. Cell Metab. 9, 525-536 (2009).
-
(2009)
Cell Metab.
, vol.9
, pp. 525-536
-
-
Dean, J.T.1
-
98
-
-
45049086849
-
Biofuel alternatives to ethanol: Pumping the microbial well
-
Fortman, J. L. et al. Biofuel alternatives to ethanol: pumping the microbial well. Trends Biotechnol. 26, 375-381 (2008).
-
(2008)
Trends Biotechnol.
, vol.26
, pp. 375-381
-
-
Fortman, J.L.1
-
99
-
-
70349281876
-
Engineering for biofuels: Exploiting innate microbial capacity or importing biosynthetic potential? Nature Rev
-
Alper, H. & Stephanopoulos, G. Engineering for biofuels: exploiting innate microbial capacity or importing biosynthetic potential? Nature Rev. Microbiol. 7, 715-723 (2009).
-
(2009)
Microbiol.
, vol.7
, pp. 715-723
-
-
Alper, H.1
Stephanopoulos, G.2
-
100
-
-
0022970603
-
Acetone-butanol fermentation revisited
-
Jones, D. T. & Woods, D. R. Acetone-butanol fermentation revisited. Microbiol. Rev. 50, 484-524 (1986).
-
(1986)
Microbiol. Rev.
, vol.50
, pp. 484-524
-
-
Jones, D.T.1
Woods, D.R.2
-
101
-
-
0037337740
-
Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum
-
Tummala, S. B., Welker, N. E. & Papoutsakis, E. T. Design of antisense RNA constructs for downregulation of the acetone formation pathway of Clostridium acetobutylicum. J. Bacteriol. 185, 1923-1934 (2003).
-
(2003)
J. Bacteriol.
, vol.185
, pp. 1923-1934
-
-
Tummala, S.B.1
Welker, N.E.2
Papoutsakis, E.T.3
-
102
-
-
36248966555
-
Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum
-
Shao, L. et al. Targeted gene disruption by use of a group II intron (targetron) vector in Clostridium acetobutylicum. Cell Res. 17, 963-965 (2007).
-
(2007)
Cell Res.
, vol.17
, pp. 963-965
-
-
Shao, L.1
-
103
-
-
38049162218
-
Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli
-
Inui, M. et al. Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli. Appl. Microbiol. Biotechnol. 77, 1305-1316 (2008).
-
(2008)
Appl. Microbiol. Biotechnol.
, vol.77
, pp. 1305-1316
-
-
Inui, M.1
-
104
-
-
38049001166
-
Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels
-
Atsumi, S., Hanai, T. & Liao, J. C. Non-fermentative pathways for synthesis of branched-chain higher alcohols as biofuels. Nature 451, 86-89 (2008).
-
(2008)
Nature
, vol.451
, pp. 86-89
-
-
Atsumi, S.1
Hanai, T.2
Liao, J.C.3
-
105
-
-
0038391517
-
Engineering a mevalonate pathway in Escherichia coli for production of terpenoids
-
Martin, V. J., Pitera, D. J., Withers, S. T., Newman, J. D. & Keasling, J. D. Engineering a mevalonate pathway in Escherichia coli for production of terpenoids. Nature Biotech. 21, 796-802 (2003).
-
(2003)
Nature Biotech.
, vol.21
, pp. 796-802
-
-
Martin, V.J.1
Pitera, D.J.2
Withers, S.T.3
Newman, J.D.4
Keasling, J.D.5
-
106
-
-
33645870422
-
Production of the antimalarial drug precursor artemisinic acid in engineered yeast
-
Ro, D. K. et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440, 940-943 (2006).
-
(2006)
Nature
, vol.440
, pp. 940-943
-
-
Ro, D.K.1
-
107
-
-
75749125061
-
Microbial production of fatty-acid-derived fuels and chemicals from plant biomass
-
Steen, E. J. et al. Microbial production of fatty-acid-derived fuels and chemicals from plant biomass. Nature 463, 559-562 (2010).
-
(2010)
Nature
, vol.463
, pp. 559-562
-
-
Steen, E.J.1
-
108
-
-
70149113922
-
Synthesis of methyl halides from biomass using engineered microbes
-
Bayer, T. S. et al. Synthesis of methyl halides from biomass using engineered microbes. J. Am. Chem. Soc. 131, 6508-6515 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 6508-6515
-
-
Bayer, T.S.1
-
109
-
-
70350493673
-
Complete reconstitution of a highly reducing iterative polyketide synthase
-
Ma, S. M. et al. Complete reconstitution of a highly reducing iterative polyketide synthase. Science 326, 589-592 (2009).
-
(2009)
Science
, vol.326
, pp. 589-592
-
-
Ma, S.M.1
-
110
-
-
8144226497
-
Total synthesis of long DNA sequences: Synthesis of a contiguous 32-kb polyketide synthase gene cluster
-
Kodumal, S. J. et al. Total synthesis of long DNA sequences: synthesis of a contiguous 32-kb polyketide synthase gene cluster. Proc. Natl Acad. Sci. USA 101, 15573-15578 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 15573-15578
-
-
Kodumal, S.J.1
-
111
-
-
24644515752
-
Tuning genetic control through promoter engineering
-
Alper, H., Fischer, C., Nevoigt, E. & Stephanopoulos, G. Tuning genetic control through promoter engineering. Proc. Natl Acad. Sci. USA 102, 12678-12683 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 12678-12683
-
-
Alper, H.1
Fischer, C.2
Nevoigt, E.3
Stephanopoulos, G.4
-
112
-
-
66149172363
-
Model-guided construction of synthetic gene networks with predicted functions
-
Ellis, T., Wang, X. & Collins, J. J. Diversity-based, model-guided construction of synthetic gene networks with predicted functions. Nature Biotech. 27, 465-471 (2009).
-
(2009)
Nature Biotech.
, vol.27
, pp. 465-471
-
-
Ellis, T.1
Wang, X.2
Diversity-Based, J.C.J.3
-
113
-
-
71849110893
-
Next-generation synthetic gene networks
-
Lu, T. K., Khalil, A. S. & Collins, J. J. Next-generation synthetic gene networks. Nature Biotech. 27, 1139-1150 (2009).
-
(2009)
Nature Biotech.
, vol.27
, pp. 1139-1150
-
-
Lu, T.K.1
Khalil, A.S.2
Collins, J.J.3
-
114
-
-
33748953866
-
Genetic parts to program bacteria
-
Voigt, C. A. Genetic parts to program bacteria. Curr. Opin. Biotechnol. 17, 548-557 (2006).
-
(2006)
Curr. Opin. Biotechnol.
, vol.17
, pp. 548-557
-
-
Voigt, C.A.1
-
115
-
-
70349303484
-
Engineering the Salmonella type III secretion system to export spider silk monomers
-
Widmaier, D. M. et al. Engineering the Salmonella type III secretion system to export spider silk monomers. Mol. Syst. Biol. 5, 309 (2009).
-
(2009)
Mol. Syst. Biol.
, vol.5
, pp. 309
-
-
Widmaier, D.M.1
-
116
-
-
67650376275
-
Adaptive prediction of environmental changes by microorganisms
-
Mitchell, A. et al. Adaptive prediction of environmental changes by microorganisms. Nature 460, 220-224 (2009).
-
(2009)
Nature
, vol.460
, pp. 220-224
-
-
Mitchell, A.1
-
117
-
-
45549085296
-
Predictive behavior within microbial genetic networks
-
Tagkopoulos, I., Liu, Y. C. & Tavazoie, S. Predictive behavior within microbial genetic networks. Science 320, 1313-1317 (2008).
-
(2008)
Science
, vol.320
, pp. 1313-1317
-
-
Tagkopoulos, I.1
Liu, Y.C.2
Tavazoie, S.3
-
118
-
-
66849127702
-
Molecular circuits for associative learning in single-celled organisms
-
Fernando, C. T. et al. Molecular circuits for associative learning in single-celled organisms. J. R. Soc. Interface 6, 463-469 (2009).
-
(2009)
J. R. Soc. Interface
, vol.6
, pp. 463-469
-
-
Fernando, C.T.1
-
119
-
-
34548533820
-
Designing sequential transcription logic: A simple genetic circuit for conditional memory
-
Fritz, G., Buchler, N. E., Hwa, T. & Gerland, U. Designing sequential transcription logic: a simple genetic circuit for conditional memory. Syst. Synth. Biol. 1, 89-98 (2007).
-
(2007)
Syst. Synth. Biol.
, vol.1
, pp. 89-98
-
-
Fritz, G.1
Buchler, N.E.2
Hwa, T.3
Gerland, U.4
-
120
-
-
0033593306
-
Molecular bases for circadian clocks
-
Dunlap, J. C. Molecular bases for circadian clocks. Cell 96, 271-290 (1999).
-
(1999)
Cell
, vol.96
, pp. 271-290
-
-
Dunlap, J.C.1
-
121
-
-
68949161807
-
Programming cells by multiplex genome engineering and accelerated evolution
-
Wang, H. H. et al. Programming cells by multiplex genome engineering and accelerated evolution. Nature 460, 894-898 (2009).
-
(2009)
Nature
, vol.460
, pp. 894-898
-
-
Wang, H.H.1
-
122
-
-
0242416539
-
Noise in eukaryotic gene expression
-
Blake, W. J., Kærn, M., Cantor, C. R. & Collins, J. J. Noise in eukaryotic gene expression. Nature 422, 633-637 (2003).
-
(2003)
Nature
, vol.422
, pp. 633-637
-
-
Blake, W.J.1
Kærn, M.2
Cantor, C.R.3
Collins, J.J.4
-
123
-
-
32844455250
-
A bottom-up approach to gene regulation
-
Guido, N. J. et al. A bottom-up approach to gene regulation. Nature 439, 856-860 (2006).
-
(2006)
Nature
, vol.439
, pp. 856-860
-
-
Guido, N.J.1
-
124
-
-
70349964350
-
Automated design of synthetic ribosome binding sites to control protein expression
-
Salis, H. M., Mirsky, E. A. & Voigt, C. A. Automated design of synthetic ribosome binding sites to control protein expression. Nature Biotech. 27, 946-950 (2009).
-
(2009)
Nature Biotech.
, vol.27
, pp. 946-950
-
-
Salis, H.M.1
Mirsky, E.A.2
Voigt, C.A.3
-
125
-
-
68449088806
-
Synthetic protein scaffolds provide modular control over metabolic flux
-
Dueber, J. E. et al. Synthetic protein scaffolds provide modular control over metabolic flux. Nature Biotech. 27, 753-759 (2009).
-
(2009)
Nature Biotech.
, vol.27
, pp. 753-759
-
-
Dueber, J.E.1
-
126
-
-
39449112551
-
Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome
-
Gibson, D. G. et al. Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome. Science 319, 1215-1220 (2008).
-
(2008)
Science
, vol.319
, pp. 1215-1220
-
-
Gibson, D.G.1
-
127
-
-
31044439550
-
Essential genes of a minimal bacterium
-
Glass, J. I. et al. Essential genes of a minimal bacterium. Proc. Natl Acad. Sci. USA 103, 425-430 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 425-430
-
-
Glass, J.I.1
-
128
-
-
34547755976
-
Genome transplantation in bacteria: Changing one species to another
-
Lartigue, C. et al. Genome transplantation in bacteria: changing one species to another. Science 317, 632-638 (2007).
-
(2007)
Science
, vol.317
, pp. 632-638
-
-
Lartigue, C.1
-
129
-
-
70349324305
-
Creating bacterial strains from genomes that have been cloned and engineered in yeast
-
Lartigue, C. et al. Creating bacterial strains from genomes that have been cloned and engineered in yeast. Science 325, 1693-1696 (2009).
-
(2009)
Science
, vol.325
, pp. 1693-1696
-
-
Lartigue, C.1
|