Structure-guided recombination creates an artificial family of cytochromes P450

PLoS Biology

Volumn 4, Issue 5, 2006, Pages 789-798

  Otey, Christopher R ^a   Landwehr, Marco ^b   Endelman, Jeffrey B ^c   Hiraga, Kaori ^b,d   Bloom, Jesse D ^b   Arnold, Frances H ^a,b,c  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b California Institute of Technology   (United States)

^c California Institute of Technology   (United States)

^d WADSWORTH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHIMERIC PROTEIN; CYTOCHROME P450; HEMOPROTEIN; LAURIC ACID DERIVATIVE; P NITROPHENOXYDODECANOIC ACID; P-NITROPHENOXYDODECANOIC ACID; RECOMBINANT PROTEIN;

ARTICLE; CATALYSIS; CELL DISRUPTION; CHIMERA; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; LOGISTIC REGRESSION ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; THERMOSTABILITY; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME STABILITY; GENETIC RECOMBINATION; GENETICS; HEAT; METABOLISM; METHODOLOGY; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN FOLDING; STATISTICAL MODEL;

AMINO ACID SEQUENCE; CYTOCHROME P-450 ENZYME SYSTEM; ENZYME STABILITY; HEAT; LAURATES; LOGISTIC MODELS; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN FOLDING; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT;

EID: 33646753362     PISSN: 15457885     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.0040112     Document Type: Article

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