Development of a panel of high-throughput reporter-gene assays to detect genotoxicity and oxidative stress

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 760, Issue , 2014, Pages 23-32

  Van der Linden, Sander C ^a   von Bergh, Anne R M ^b   van Vught Lussenburg, Barbara M A ^a   Jonker, Lydia R A ^a   Teunis, Marc ^b   Krul, Cyrille A M ^b   van der Burg, Bart ^a  

^a BIODETECTION SYSTEMS B V   (Netherlands)

^b UNIVERSITY OF APPLIED SCIENCES UTRECHT   (Netherlands)

Author keywords

CALUX; Genotoxicity; High throughput screening; Oxidative stress

Indexed keywords

LUCIFERASE; NFE2L2 PROTEIN, HUMAN; PROTEIN P53; TRANSCRIPTION FACTOR NRF2; XENOBIOTIC AGENT;

CELL SURVIVAL; CLASSIFICATION; DNA DAMAGE; DNA RESPONSIVE ELEMENT; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HUMAN; LUMINESCENCE; METABOLISM; MUTAGEN TESTING; OXIDATIVE STRESS; PROCEDURES; REPORTER GENE; REPRODUCIBILITY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, REPORTER; HUMANS; LUCIFERASES; LUMINESCENT MEASUREMENTS; MUTAGENICITY TESTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; XENOBIOTICS;

EID: 84895065935     PISSN: 13835718     EISSN: 18793592     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2013.09.009     Document Type: Article

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