A pre-validation transferability study of the GreenScreen HC GADD45a-GFP assay with a metabolic activation system (S9)

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 700, Issue 1-2, 2010, Pages 44-50

  Billinton, Nicholas ^a   Bruce, Shannon ^b   Hansen, Julia Rytter ^c   Hastwell, Paul W ^d   Jagger, Christopher ^a   McComb, Catriona ^d   Klug, Michelle L ^b   Pant, Kamala ^b   Rabinowitz, Adam ^a   Rees, Robert ^d   Tate, Matthew ^a,e   Vinggaard, Anne Marie ^c   Walmsley, Richard M ^a,e  

^a Gentronix Ltd   (United Kingdom)

^b BioReliance Corporation   (United States)

^c LEO PHARMA A S   (Denmark)

^d GLAXOSMITHKLINE   (United Kingdom)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

ECVAM; GADD45a; Genotoxicity; GreenScreen HC; Pre validation; Transferability

Indexed keywords

2,4 DINITROPHENOL; 6 CHRYSENAMINE; AFLATOXIN B1; AROCLOR 1254; BENZO[A]PYRENE; CHRYSENE DERIVATIVE; CYCLOPHOSPHAMIDE; GREEN FLUORESCENT PROTEIN; MANNITOL; PHENFORMIN; PHTHALIC ANHYDRIDE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASSAY; CELL VIABILITY; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE; GENOTOXICITY; GREENSCREEN HUMAN CELL GADD45A GENE GFP GENE GENOTOXICITY ASSAY; HUMAN; HUMAN CELL; MALE; METABOLIC ACTIVATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; RELIABILITY; REPORTER GENE; REPRODUCIBILITY; VALIDATION PROCESS;

BIOTRANSFORMATION; CELL CYCLE PROTEINS; CELL LINE; GREEN FLUORESCENT PROTEINS; HUMANS; MUTAGENICITY TESTS; NUCLEAR PROTEINS; REPRODUCIBILITY OF RESULTS;

EID: 77953916495     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2010.05.001     Document Type: Article

References (12)

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