Biochemical characterization of rat P450 2C11 fused to rat or bacterial NADPH-P450 reductase domains

Biochemistry

Volumn 39, Issue 17, 2000, Pages 5196-5205

  Helvig, Christian ^a   Capdevila, Jorge H ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C; CYTOCHROME P450; CYTOCHROME P450 REDUCTASE; HEME; HYDROGEN PEROXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME MECHANISM; ENZYME METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; RAT; REDUCTION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BACTERIAL PROTEINS; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; NADH, NADPH OXIDOREDUCTASES; NADPH-FERRIHEMOPROTEIN REDUCTASE; PROTEIN ENGINEERING; PROTEIN FOLDING; RATS; RECOMBINANT FUSION PROTEINS; STEROID 16-ALPHA-HYDROXYLASE; STEROID HYDROXYLASES;

ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; RODENTIA;

EID: 0034595407     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi992578v     Document Type: Article

References (55)

1. Makita, K., Falck, J. R., and Capdevila, J. H. (1996) FASEB J. 10, 1456-1463.
2. Kagawa, N., and Waterman, M. R. (1995) in Cytochrome P450: Structure and Biochemistry (de Montellano, P. O., Ed.) pp 419-442, Plenum Press, New York.
3. Fu, O. K., Portale, A. A., and Miller, W. L. (1997) DNA Cell Biol. 16, 1499-1507.
4. Li, J., Nagpal, P., Vitart, V., McMorris, T. C., and Chory, J. (1996) Science 272, 398-401.
5. Murakami, H., Yabusaki, Y., Sakaki, M., and Ohkawa, H. (1987) DNA 6, 189-197.
6. Shet, M. S., Fisher, C. W., Arlotto, M. P., Shackleton, C. H., Holmans, P. L., Martin-Wixtrom, C. A., Saeki, Y., and Estabrook R. W. (1994) Arch. Biochem. Biophys. 311, 402-417.
7. Fisher, C. W., Shet, M. S., and Estabrook, R. W. (1996) Methods Enzymol. 272, 15-25.
8. Shet, M. S., Faulkner, K. M., Holmans, P. L., Fisher, C. W., and Estabrook R. W. (1995) Arch. Biochem. Biophys. 318, 314-321.
9. Fisher, C. W., Shet, M. S., Claudle, D. L., Martin-Wixtrom, C. A., and Estabrook (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 10817-10821.
10. Narhi, L. O., and Fulco, A. J. (1986) J. Biol. Chem. 261, 7160-7169.
11. Wen, L. P., and Fulco A. J. (1987) J. Biol. Chem. 262, 6676-6682.
12. Graham-Lorence, S., Truan, G., Peterson, J. A., Falck, J. R., Wei, S., Helvig, C., and Capdevila, J. H. (1997) J. Biol. Chem. 272, 1127-1135.
13. Miura, Y., and Fulco, A. J. (1975) Biochim. Biophys. Acta 388, 305-317.
14. Ho, P. P., and Fulco A. J. (1976) Biochim. Biophys. Acta 431, 249-256.
15. Ravichandran, K. G., Boddupalli, S. S., Hasermann, C. A., Peterson, J. A., and Deisenhofer, J. (1993) Science 261, 731-736.
16. McMillan, K., Bredt, D. S., Hirsch, D. J., Snyder, S. H., Clarck, J. E., and Master, B. S. I. (1992) Proc. Natl. Acad. Sci. U.S.A. 89, 11141-11145.
17. Geller, D. A., Lowenstein, C. J., Shapiro, R. A., Nussler, A. K., DiSilvio, M., Wang S. C., Nakayama, O. K., Simmons, R. L, Snyder, S. H., and Billiar, T. R. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 3491-3495.
18. Nakayama, N., Takemae, A., and Shoun H. (1996) J. Biochem. 119, 435-440.
19. Oliw, E. H., Bylund, J., and Herman, C. (1996) Lipids 31, 1003-1021.
20. MacGiff, J. C., Steinberg, M., and Quilley, J. (1996) Trends Cardiovasc. Med. 6, 4-10.
21. Harder, D. R., Lange, A. R., Gebremedhin, D., Birks, E. K., and Roman, R. J. (1997) J. Vasc. Res. 32, 79-92.
22. McGiff, J. C., and Quilley, J. (1999) Am. J. Physiol. 277, R607-R623.
23. Stec, D. E., Deng, A. Y., Rapp, J. P., and Roman, R. J. (1996) Hypertension 27, 564-568.
24. Karara, A., Makita, K., Jacobson, H. R., Falck, J. R., Guengerich, F. P., DuBois, R. N., and Capdevila, J. H. (1993) J. Biol. Chem. 268, 13565-13570.
25. Cederbaum, A. I. (1998) Biofactors 8, 93-96.
26. Guengerich, F. P., Dannan, G. A., Wright, S. T., Martin, M. V., and Kaminsky, L. S. (1982) Biochemistry 21, 6019-6030.
27. Gillam, E. M., Baba, T., Kim, B. R., Ohmori, S., and Guengerich, F. P. (1993) Arch. Biochem. Biophys. 305, 123-131.
28. Gillam, E. M., Guo, Z., Ueng, Y. F., Yamazaki, H., Cock, I., Reilly, P. E., Hooper, W. D., and Guengerich, F. P. (1995) Arch. Biochem. Biophys. 317, 374-384.
29. Boddupali, S. S., Oster, T., Estabroock, R. W., and Peterson, J. A. (1992) J. Biol. Chem. 267, 10375-10380.
30. Porter, T. D., and Kasper, C. B. (1985) Proc. Natl. Acad. Sci. U.S.A. 82, 973-977.
31. Govindaraj, S., and Poulos, T. L. (1995) Biochemistry 34, 11221-11226.
32. Ruettinger, R. T., Wen, L. P., and Fulco, A. J. (1989) J. Biol. Chem. 264, 10987-10995.
33. Bauer, S., and Shiloach, J. (1974) Biotechnol. Bioeng. 16, 933-941.
34. Omura, T., and Sato, R. (1964) J. Biol. Chem. 239, 2370-2378.
35. Capdevila, J. H., Falck, J. R., Dishman, E., and Karara, A. (1990) Methods Enzymol. 187, 385-394.
36. Capdevila, J. H., Wei, S., Yan, Y., Karara, A., Jacobson, H. R., Falk, J. R., Guengerich, F. P., and Dubois, R. N. (1992) J. Biol. Chem. 267, 21720-21726.
37. Hildebrandt, A. G., and Roots, I. (1975) Arch. Biochem. Biophys. 171, 385-397.
38. Barnes, H. J., Arlotto, M. P., and Waterman, M. R. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 5597-5601.
39. Barnes, H. (1996) Methods Enzymol. 272, 3-14.
40. Pernecky, S. J., and Coon M. J. (1996) Methods Enzymol. 272, 25-34.
41. Jenkins, C. M., and Waterman, M. R. (1998) Biochemistry 37, 6106-6113.
42. Helvig, C., Dishman, E., and Capdevila, J. H. (1998) Biochemistry 37, 12546-12558.
43. Shet, M. S., Fisher, C. W., Holmans, P. L, and Estabrook R. W. (1996) Arch. Biochem. Biophys. 330, 199-208.
44. Lu, A. Y. H., Junk, K. W., and Coon, M. J. (1969) J. Biol. Chem. 244, 3714-3721.
45. Black, S. D., and Coon, M. J. (1982) J. Biol. Chem. 257, 5929-5938.
46. Parikh, A., and Guengerich, F. P. (1997) Protein Expression Purif. 3, 346-354.
47. Chaurasia, C. S., Alterman, M. A., Lu, P., and Hanziik, P. P. (1995) Arch. Biochem. Biophys. 317, 161-169.
48. Govindaraj, S., and Poulos, T. L. (1996) Protein Sci. 5, 1389-1393.
49. Gunsalus, I. C., Meeks, J. R., Lipscomb, J. D., Debrunner, P., and Munck, E. (1974) in Molecular Mechanisms of Oxygen Activation (Hayaishi, O., Ed.) Chapter 14, pp 559-613, Academic Press, New York.
50. Makino, R., Iizuka, T., Sakaguchi, K., and Ishimura, Y. (1982) in Oxygenase and Oxygen Metabolism (Nozaki, M., Yamamoto, S., Ishimura, Y., Coon, M. J., Ernster, L., and Estabrook, R. W., Eds.) pp 467-477, Academic Press, New York.
51. Loida, P. J., and Sligar, S. G. (1993) Biochemistry 32, 11530-11538.
52. Li, H., and Poulos, T. L. (1997) Nat. Struct. Biol. 4, 140-146.
53. Li, H. Y., and Poulos, T. L. (1995) Acta Crystallogr. D51, 21-32.
54. Modi, S., Primrose, W. U., Boyle, J. M. B., Gibson, C. F., Lian, L.-Y., and Roberts, G. C. K. (1995) Biochemistry 4, 8982-8988.
55. Chen, J. K., Wang, D. W., Falck, J. R., Capdevila, J., and Harris, R. C. (1999) J. Biol. Chem. 274, 4764-4769.