Protein delivery using engineered virus-like particles

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 41, 2011, Pages 16998-17003

  Kaczmarczyk, Stanislaw J ^a   Sitaraman, Kalavathy ^a   Young, Howard A ^b   Hughes, Stephen H ^b   Chatterjee, Deb K ^a  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Surface display; TRAIL

Indexed keywords

APOPTOSIS INDUCING FACTOR; CAPSID PROTEIN; DNA; FLUCYTOSINE; FLUOROURACIL; GAG PROTEIN; GAMMA INTERFERON; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; POL PROTEIN; RETROVIRUS VECTOR; STAT1 PROTEIN; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; BIOSAFETY; CANCER CHEMOTHERAPY; CELL VIABILITY; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; CYTOSOL; DRUG CYTOTOXICITY; EMBRYO; ENZYME ACTIVITY; GENOME; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; VIRAL GENE DELIVERY SYSTEM; VIRUS ENTRY; VIRUS LIKE AGENT;

ANIMALS; BASE SEQUENCE; CELL LINE; DNA, RECOMBINANT; GENES, GAG; GENETIC VECTORS; HEK293 CELLS; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; HUMANS; INTERFERON-GAMMA; MICE; MOLECULAR SEQUENCE DATA; RECOMBINANT FUSION PROTEINS; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSDUCTION, GENETIC; VACCINES, VIRUS-LIKE PARTICLE;

AVIAN RETROVIRUS; MURINAE;

EID: 80054762005     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1101874108     Document Type: Article

References (42)

1. Federspiel MJ, Bates P, Young JA, Varmus HE, Hughes SH (1994) A system for tissue-specific gene targeting: Transgenic mice susceptible to subgroup A avian leukosis virus-based retroviral vectors. Proc Natl Acad Sci USA 91:11241-11245. (Pubitemid 24349662)
2. Bockamp E, et al. (2008) Conditional transgenic mouse models: From the basics to genome-wide sets of knockouts and current studies of tissue regeneration. Regen Med 3:217-235. (Pubitemid 351546461)
3. Hare S, et al. (2009) A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75. PLoS Pathog 5:e1000259.
4. Huang S, Kawabe Y, Ito A, Kamihira M (2010) Cre recombinase-mediated site-specific modification of a cellular genome using an integrase-defective retroviral vector. Biotechnol Bioeng 107:717-729.
5. Capecchi MR (1980) High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell 22:479-488.
6. Bar-Sagi D, Feramisco JR (1985) Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation. Cell 42:841-848.
7. Campbell PL, McCluskey J, Yeo JP, Toh BH (1995) Electroporation of antibodies into mammalian cells. Methods Mol Biol 48:83-92.
8. Abarzúa P, LoSardo JE, Gubler ML, Neri A (1995) Microinjection of monoclonal anti-body PAb421 into human SW480 colorectal carcinoma cells restores the transcription activation function to mutant p53. Cancer Res 55:3490-3494.
9. Theiss C, Meller K (2002) Microinjected anti-actin antibodies decrease gap junctional intercellular commmunication in cultured astrocytes. Exp Cell Res 281:197-204. (Pubitemid 36250364)
10. Narayanan A, et al. (2003) Nuclear RanGTP is not required for targeting small nucleolar RNAs to the nucleolus. J Cell Sci 116:177-186. (Pubitemid 36113976)
11. Schwarze SR, Hruska KA, Dowdy SF (2000) Protein transduction: Unrestricted delivery into all cells? Trends Cell Biol 10:290-295. (Pubitemid 30387038)
12. Fenton M, Bone N, Sinclair AJ (1998) The efficient and rapid import of a peptide into primary B and T lymphocytes and a lymphoblastoid cell line. J Immunol Methods 212: 41-48. (Pubitemid 28288185)
13. Murriel CL, Dowdy SF (2006) Influence of protein transduction domains on intracellular delivery of macromolecules. Expert Opin Drug Deliv 3:739-746. (Pubitemid 44781846)
14. Richard JP, et al. (2003) Cell-penetrating peptides. A reevaluation of the mechanism of cellular uptake. J Biol Chem 278:585-590. (Pubitemid 36043612)
15. Schwarze SR, Dowdy SF (2000) In vivo protein transduction: Intracellular delivery of biologically active proteins, compounds and DNA. Trends Pharmacol Sci 21:45-48. (Pubitemid 30100337)
16. Säälik P, et al. (2004) Protein cargo delivery properties of cell-penetrating peptides. A comparative study. Bioconjug Chem 15:1246-1253. (Pubitemid 39552013)
17. Drin G, Cottin S, Blanc E, Rees AR, Temsamani J (2003) Studies on the internalization mechanism of cationic cell-penetrating peptides. J Biol Chem 278:31192-31201. (Pubitemid 36994635)
18. Fischer R, Köhler K, Fotin-Mleczek M, Brock R (2004) A stepwise dissection of the intracellular fate of cationic cell-penetrating peptides. J Biol Chem 279:12625-12635. (Pubitemid 38445834)
19. Wagstaff KM, Jans DA (2006) Protein transduction: Cell penetrating peptides and their therapeutic applications. Curr Med Chem 13:1371-1387.
20. Ramqvist T, Andreasson K, Dalianis T (2007) Vaccination, immune and gene therapy based on virus-like particles against viral infections and cancer. Expert Opin Biol Ther 7:997-1007. (Pubitemid 47204356)
21. Grgacic EV, Anderson DA (2006) Virus-like particles: Passport to immune recognition. Methods 40:60-65. (Pubitemid 44415499)
22. Garcea RL, Gissmann L (2004) Virus-like particles as vaccines and vessels for the delivery of small molecules. Curr Opin Biotechnol 15:513-517. (Pubitemid 39551003)
23. Ludwig C, Wagner R (2007) Virus-like particles-universal molecular toolboxes. Curr Opin Biotechnol 18:537-545.
24. Jennings GT, Bachmann MF (2008) The coming of age of virus-like particle vaccines. Biol Chem 389:521-536. (Pubitemid 351874198)
25. Peretti S, Schiavoni I, Pugliese K, Federico M (2005) Cell death induced by the herpes simplex virus-1 thymidine kinase delivered by human immunodeficiency virus-1-based virus-like particles. Mol Ther 12:1185-1196. (Pubitemid 41723053)
26. Peretti S, Schiavoni I, Pugliese K, Federico M (2006) Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles. Virology 345:115-126. (Pubitemid 43107577)
27. Muratori C, Bona R, Federico M (2010) Lentivirus-based virus-like particles as a new protein delivery tool. Methods Mol Biol 614:111-124.
28. Voelkel C, et al. (2010) Protein transduction from retroviral Gag precursors. Proc Natl Acad Sci USA 107:7805-7810.
29. Voynow SL, Coffin JMJ (1985) Truncated gag-related proteins are produced by large deletion mutants of Rous sarcoma virus and form virus particles. J Virol 55:79-85. (Pubitemid 15048692)
30. Krishna NK, Campbell S, Vogt VM, Wills JW (1998) Genetic determinants of Rous sarcoma virus particles size. J Virol 72:564-577. (Pubitemid 28048873)
31. Weldon RA, Jr., Erdie CR, Oliver MG, Wills JW (1990) Incorporation of chimeric gag protein into retroviral particles. J Virol 64:4169-4179. (Pubitemid 20279824)
32. Vogt VM, Simon MN (1999) Mass determination of Rous sarcoma virus virions by scanning transmission electron microscopy. J Virol 73:7050-7055. (Pubitemid 29327893)
33. Hughes SH, Greenhouse JJ, Petropoulos CJ, Sutrave P (1987) Adaptor plasmids simplify the insertion of foreign DNA into helper-independent retroviral vectors. J Virol 61: 3004-3012. (Pubitemid 17131484)
34. Coffin JM, Hughes SH, Varmus, HE, eds (1997) Retroviruses (Cold Spring Harbor Lab Press, Cold Spring Harbor, NY).
35. Lindberg LG (1968) Virus-like particles in Rous rat sarcoma. Acta Pathol Microbiol Scand 74:189-198.
36. Kaczmarczyk SJ, Green JE (2001) A single vector containing modified cre recombinase and LOX recombination sequences for inducible tissue-specific amplification of gene expression. Nucleic Acids Res 29:e56.
37. Corish P, Tyler-Smith C (1999) Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 12:1035-1040. (Pubitemid 30011478)
38. LeBlanc HN, Ashkenazi A (2003) Apo2L/TRAIL and its death and decoy receptors. Cell Death Differ 10:66-75. (Pubitemid 36511833)
39. Falschlehner C, Emmerich CH, Gerlach B, Walczak H (2007) TRAIL signalling: Decisions between life and death. Int J Biochem Cell Biol 39:1462-1475. (Pubitemid 47031030)
40. Walczak H, et al. (1999) Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 5:157-163. (Pubitemid 29068521)
41. Yang Y, Leggat D, Herbert A, Roberts PC, Sundick RS (2009) A novel method to incorporate bioactive cytokines as adjuvants on the surface of virus particles. J Interferon Cytokine Res 29:9-22.
42. Carr CM, Kim PS (1993) A spring-loaded mechanism for the conformational change of influenza hemagglutinin. Cell 73:823-832. (Pubitemid 23159019)