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Volumn 13, Issue 12, 2016, Pages 691-706

Diet, microorganisms and their metabolites, and colon cancer

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; BUTYRIC ACID; CARCINOGEN; PLANT MEDICINAL PRODUCT; PROTEIN; SHORT CHAIN FATTY ACID; BUTYRIC ACID DERIVATIVE; FAT INTAKE;

EID: 84995414949     PISSN: 17595045     EISSN: 17595053     Source Type: Journal    
DOI: 10.1038/nrgastro.2016.165     Document Type: Review
Times cited : (808)

References (187)
  • 2
    • 84901020302 scopus 로고    scopus 로고
    • Geographic variation in colorectal cancer incidence and mortality age of onset and stage at diagnosis among American Indian and Alaska Native people 1990-2009
    • Perdue, D. G., Haverkamp, D., Perkins, C., Daley, C. M. & Provost, E. Geographic variation in colorectal cancer incidence and mortality, age of onset, and stage at diagnosis among American Indian and Alaska Native people, 1990-2009. Am. J. Public Health 104, S404-S414 (2014).
    • (2014) Am. J. Public Health , vol.104 , pp. S404-S414
    • Perdue, D.G.1    Haverkamp, D.2    Perkins, C.3    Daley, C.M.4    Provost, E.5
  • 3
    • 78049353079 scopus 로고    scopus 로고
    • Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33
    • Houlston, R. S. et al. Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26. 2, 12q13. 13 and 20q13. 33. Nat. Genet. 42, 973-977 (2010).
    • (2010) Nat. Genet. , vol.42 , pp. 973-977
    • Houlston, R.S.1
  • 4
    • 84901304828 scopus 로고    scopus 로고
    • Genome-wide diet-gene interaction analyses for risk of colorectal cancer
    • Figueiredo, J. C. et al. Genome-wide diet-gene interaction analyses for risk of colorectal cancer. PLoS Genet. 10, e1004228 (2014).
    • (2014) PLoS Genet. , vol.10 , pp. e1004228
    • Figueiredo, J.C.1
  • 5
    • 82255183575 scopus 로고    scopus 로고
    • Dietary fibre, whole grains, and risk of colorectal cancer: Systematic review and dose-response meta-analysis of prospective studies
    • Aune, D. et al. Dietary fibre, whole grains, and risk of colorectal cancer: systematic review and dose-response meta-analysis of prospective studies. BMJ 343, d6617 (2011).
    • (2011) BMJ , vol.343 , pp. d6617
    • Aune, D.1
  • 6
    • 82555191404 scopus 로고    scopus 로고
    • Dietary patterns and colorectal cancer: Systematic review and meta-analysis
    • Magalhães, B., Peleteiro, B. & Lunet, N. Dietary patterns and colorectal cancer: systematic review and meta-analysis. Eur. J. Cancer Prev. 21, 15-23 (2012).
    • (2012) Eur. J. Cancer Prev. , vol.21 , pp. 15-23
    • Magalhães, B.1    Peleteiro, B.2    Lunet, N.3
  • 9
    • 0019829568 scopus 로고
    • The causes of cancer: Quantitative estimates of avoidable risks of cancer in the United States today
    • Doll, R. & Peto, R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J. Natl Cancer Inst. 66, 1191-1308 (1981).
    • (1981) J. Natl Cancer Inst. , vol.66 , pp. 1191-1308
    • Doll, R.1    Peto, R.2
  • 10
    • 84930738140 scopus 로고    scopus 로고
    • Doll and Peto's quantitative estimates of cancer risks: Holding generally true for 35 years
    • Blot, W. J. & Tarone, R. E. Doll and Peto's quantitative estimates of cancer risks: holding generally true for 35 years. J. Natl Cancer Inst. 107, 44 (2015).
    • (2015) J. Natl Cancer Inst. , vol.107 , pp. 44
    • Blot, W.J.1    Tarone, R.E.2
  • 11
    • 0027104489 scopus 로고
    • Cancer in Japanese migrants to Hawaii: Interaction between genes and environment [French]
    • Le Marchand, L. & Kolonel, L. N. Cancer in Japanese migrants to Hawaii: interaction between genes and environment [French]. Rev. Épidémiol. Santé Publique 40, 425-430 (1992).
    • (1992) Rev. Épidémiol. Santé Publique , vol.40 , pp. 425-430
    • Le Marchand, L.1    Kolonel, L.N.2
  • 12
    • 84954441185 scopus 로고    scopus 로고
    • Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer
    • Nosho, K. et al. Association of Fusobacterium nucleatum with immunity and molecular alterations in colorectal cancer. World J. Gastroenterol. 22, 557-566 (2016).
    • (2016) World J. Gastroenterol. , vol.22 , pp. 557-566
    • Nosho, K.1
  • 13
    • 84863989936 scopus 로고    scopus 로고
    • A bacterial driver-passenger model for colorectal cancer: Beyond the usual suspects
    • Tjalsma, H., Boleij, A., Marchesi, J. R. & Dutilh, B. E. A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects. Nat. Rev. Microbiol. 10, 575-582 (2012).
    • (2012) Nat. Rev. Microbiol. , vol.10 , pp. 575-582
    • Tjalsma, H.1    Boleij, A.2    Marchesi, J.R.3    Dutilh, B.E.4
  • 14
    • 10044221016 scopus 로고    scopus 로고
    • Colorectal cancers in a new mouse model of familial adenomatous polyposis: Influence of genetic and environmental modifiers
    • Colnot, S. et al. Colorectal cancers in a new mouse model of familial adenomatous polyposis: influence of genetic and environmental modifiers. Lab. Invest. 84, 1619-1630 (2004).
    • (2004) Lab. Invest. , vol.84 , pp. 1619-1630
    • Colnot, S.1
  • 15
    • 44349149886 scopus 로고    scopus 로고
    • Butyrate and Wnt signaling: A possible solution to the puzzle of dietary fiber and colon cancer risk
    • Bordonaro, M., Lazarova, D. L. & Sartorelli, A. C. Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk Cell Cycle 7, 1178-1183 (2008).
    • (2008) Cell Cycle , vol.7 , pp. 1178-1183
    • Bordonaro, M.1    Lazarova, D.L.2    Sartorelli, A.C.3
  • 16
    • 0346749816 scopus 로고    scopus 로고
    • Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources
    • Beyer-Sehlmeyera, G. et al. Butyrate is only one of several growth inhibitors produced during gut flora-mediated fermentation of dietary fibre sources. Br. J. Nutr. 90, 1057-1070 (2003).
    • (2003) Br. J. Nutr. , vol.90 , pp. 1057-1070
    • Beyer-Sehlmeyera, G.1
  • 17
    • 84896724766 scopus 로고    scopus 로고
    • Molecular pathways: Gene-environment interactions regulating dietary fiber induction of proliferation and apoptosis via butyrate for cancer prevention
    • Bultman, S. J. Molecular pathways: gene-environment interactions regulating dietary fiber induction of proliferation and apoptosis via butyrate for cancer prevention. Clin. Cancer Res. 20, 799-803 (2014).
    • (2014) Clin. Cancer Res. , vol.20 , pp. 799-803
    • Bultman, S.J.1
  • 18
    • 84880331190 scopus 로고    scopus 로고
    • Cancer control and prevention: Nutrition and epigenetics
    • Verma, M. Cancer control and prevention: nutrition and epigenetics. Curr. Opin. Clin. Nutr. Metab. Care 16, 376-384 (2013).
    • (2013) Curr. Opin. Clin. Nutr. Metab. Care , vol.16 , pp. 376-384
    • Verma, M.1
  • 19
    • 84857782140 scopus 로고    scopus 로고
    • Modulation of Wnt/-catenin signaling pathway by bioactive food components
    • Tarapore, R. S., Siddiqui, I. A. & Mukhtar, H. Modulation of Wnt/-catenin signaling pathway by bioactive food components. Carcinogenesis 33, 483-491 (2012).
    • (2012) Carcinogenesis , vol.33 , pp. 483-491
    • Tarapore, R.S.1    Siddiqui, I.A.2    Mukhtar, H.3
  • 20
    • 84871883810 scopus 로고    scopus 로고
    • A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate
    • Fung, K. Y., Cosgrove, L., Lockett, T., Head, R. & Topping, D. L. A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate. Br. J. Nutr. 108, 820-831 (2012).
    • (2012) Br. J. Nutr. , vol.108 , pp. 820-831
    • Fung, K.Y.1    Cosgrove, L.2    Lockett, T.3    Head, R.4    Topping, D.L.5
  • 21
    • 84876953807 scopus 로고    scopus 로고
    • Epithelial cell proliferation arrest induced by lactate and acetate from Lactobacillus casei and Bifidobacterium breve
    • Matsuki, T. et al. Epithelial cell proliferation arrest induced by lactate and acetate from Lactobacillus casei and Bifidobacterium breve. PLoS ONE 8, e63053 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e63053
    • Matsuki, T.1
  • 22
    • 84963615071 scopus 로고    scopus 로고
    • Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats
    • Hu, Y. et al. Manipulation of the gut microbiota using resistant starch is associated with protection against colitis-associated colorectal cancer in rats. Carcinogenesis 37, 366-375 (2016).
    • (2016) Carcinogenesis , vol.37 , pp. 366-375
    • Hu, Y.1
  • 23
    • 84923916886 scopus 로고    scopus 로고
    • The interrelationships of the gut microbiome and inflammation in colorectal carcinogenesis
    • Cho, M., Carter, J., Harari, S. & Pei, Z. The interrelationships of the gut microbiome and inflammation in colorectal carcinogenesis. Clin. Lab. Med. 34, 699-710 (2014).
    • (2014) Clin. Lab. Med. , vol.34 , pp. 699-710
    • Cho, M.1    Carter, J.2    Harari, S.3    Pei, Z.4
  • 24
    • 79960895388 scopus 로고    scopus 로고
    • Microbial induction of immunity, inflammation and cancer
    • Greer, J. B. & O'Keefe, S. J. Microbial induction of immunity, inflammation and cancer. Front. Physiol. 1, 168 (2011).
    • (2011) Front. Physiol. , vol.1 , pp. 168
    • Greer, J.B.1    O'Keefe, S.J.2
  • 25
    • 84966389294 scopus 로고    scopus 로고
    • Diet microbiota and dysbiosis: A 'recipe' for colorectal cancer
    • Vipperla, K. & O'Keefe, S. J. Diet, microbiota, and dysbiosis: a 'recipe' for colorectal cancer. Food Funct. 7, 1731-1740 (2016).
    • (2016) Food Funct. , vol.7 , pp. 1731-1740
    • Vipperla, K.1    O'Keefe, S.J.2
  • 26
    • 0029813545 scopus 로고    scopus 로고
    • Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4+ TH1-like responses
    • Berg, D. J. et al. Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4+ TH1-like responses. J. Clin. Invest. 98, 1010-1020 (1996).
    • (1996) J. Clin. Invest. , vol.98 , pp. 1010-1020
    • Berg, D.J.1
  • 27
    • 67650299380 scopus 로고    scopus 로고
    • Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility
    • Uronis, J. M. et al. Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility. PLoS ONE 4, e6026 (2009).
    • (2009) PLoS ONE , vol.4 , pp. e6026
    • Uronis, J.M.1
  • 29
    • 84924040920 scopus 로고    scopus 로고
    • Structure of the gut microbiome following colonization with human feces determines colonic tumor burden
    • Baxter, N. T., Zackular, J. P., Chen, G. Y. & Schloss, P. D. Structure of the gut microbiome following colonization with human feces determines colonic tumor burden. Microbiome 2, 20 (2014).
    • (2014) Microbiome , vol.2 , pp. 20
    • Baxter, N.T.1    Zackular, J.P.2    Chen, G.Y.3    Schloss, P.D.4
  • 30
    • 84891585929 scopus 로고    scopus 로고
    • The gut microbiome modulates colon tumorigenesis
    • Zackular, J. P. et al. The gut microbiome modulates colon tumorigenesis. mBio 4, e00692-13 (2013).
    • (2013) MBio , vol.4 , pp. e00692-e00713
    • Zackular, J.P.1
  • 31
    • 84924026956 scopus 로고    scopus 로고
    • Potential of fecal microbiota for early-stage detection of colorectal cancer
    • Zeller, G. et al. Potential of fecal microbiota for early-stage detection of colorectal cancer. Mol. Syst. Biol. 10, 766 (2014).
    • (2014) Mol. Syst. Biol. , vol.10 , pp. 766
    • Zeller, G.1
  • 32
    • 84882354326 scopus 로고    scopus 로고
    • Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment
    • Kostic, A. D. et al. Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor-immune microenvironment. Cell Host Microbe 14, 207-215 (2013).
    • (2013) Cell Host Microbe , vol.14 , pp. 207-215
    • Kostic, A.D.1
  • 33
    • 85010756263 scopus 로고    scopus 로고
    • Fusobacterium nucleatum and T cells in colorectal carcinoma
    • Mima, K. et al. Fusobacterium nucleatum and T cells in colorectal carcinoma. JAMA Oncol. 1, 653-661 (2015).
    • (2015) JAMA Oncol. , vol.1 , pp. 653-661
    • Mima, K.1
  • 34
    • 84896527392 scopus 로고    scopus 로고
    • Fusobacterium in colonic flora and molecular features of colorectal carcinoma
    • Tahara, T. et al. Fusobacterium in colonic flora and molecular features of colorectal carcinoma. Cancer Res. 74, 1311-1318 (2014).
    • (2014) Cancer Res. , vol.74 , pp. 1311-1318
    • Tahara, T.1
  • 35
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu, S. et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat. Med. 15, 1016-1022 (2009).
    • (2009) Nat. Med. , vol.15 , pp. 1016-1022
    • Wu, S.1
  • 36
    • 33745593712 scopus 로고    scopus 로고
    • A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer
    • Toprak, N. U. et al. A possible role of Bacteroides fragilis enterotoxin in the aetiology of colorectal cancer. Clin. Microbiol. Infect. 12, 782-786 (2006).
    • (2006) Clin. Microbiol. Infect. , vol.12 , pp. 782-786
    • Toprak, N.U.1
  • 37
    • 84979256218 scopus 로고    scopus 로고
    • Reduction of murine colon tumorigenesis driven by enterotoxigenic Bacteroides fragilis using cefoxitin treatment
    • DeStefano Shields, C. E. et al. Reduction of murine colon tumorigenesis driven by enterotoxigenic Bacteroides fragilis using cefoxitin treatment. J. Infect. Dis. 214, 122-129 (2016).
    • (2016) J. Infect. Dis. , vol.214 , pp. 122-129
    • DeStefano Shields, C.E.1
  • 38
    • 84899121453 scopus 로고    scopus 로고
    • Microbiota of human breast tissue
    • Urbaniak, C. et al. Microbiota of human breast tissue. Appl. Environ. Microbiol. 80, 3007-3014 (2014).
    • (2014) Appl. Environ. Microbiol. , vol.80 , pp. 3007-3014
    • Urbaniak, C.1
  • 39
    • 84905966663 scopus 로고    scopus 로고
    • The gut microbiota and developmental programming of the testis in mice
    • Al-Asmakh, M. et al. The gut microbiota and developmental programming of the testis in mice. PLoS ONE 9, e103809 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e103809
    • Al-Asmakh, M.1
  • 40
    • 84961620579 scopus 로고    scopus 로고
    • Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid
    • Collado, M. C., Rautava, S., Aakko, J., Isolauri, E. & Salminen, S. Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid. Sci. Rep. 6, 23129 (2016).
    • (2016) Sci. Rep. , vol.6 , pp. 23129
    • Collado, M.C.1    Rautava, S.2    Aakko, J.3    Isolauri, E.4    Salminen, S.5
  • 41
    • 84905876836 scopus 로고    scopus 로고
    • Cancer-promoting effects of microbial dysbiosis
    • Sheflin, A. M., Whitney, A. K. & Weir, T. L. Cancer-promoting effects of microbial dysbiosis. Curr. Oncol. Rep. 16, 406 (2014).
    • (2014) Curr. Oncol. Rep. , vol.16 , pp. 406
    • Sheflin, A.M.1    Whitney, A.K.2    Weir, T.L.3
  • 42
    • 84897449654 scopus 로고    scopus 로고
    • Microbial dysbiosis is associated with human breast cancer
    • Xuan, C. et al. Microbial dysbiosis is associated with human breast cancer. PLoS ONE 9, e83744 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e83744
    • Xuan, C.1
  • 43
    • 84919643021 scopus 로고    scopus 로고
    • High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity
    • Schulz, M. D. et al. High-fat-diet-mediated dysbiosis promotes intestinal carcinogenesis independently of obesity. Nature 514, 508-512 (2014).
    • (2014) Nature , vol.514 , pp. 508-512
    • Schulz, M.D.1
  • 44
    • 77949371211 scopus 로고    scopus 로고
    • 99th Dahlem conference on infection inflammation and chronic inflammatory disorders: Darwinian medicine and the 'hygiene' or 'old friends' hypothesis
    • Rook, G. A. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: Darwinian medicine and the 'hygiene' or 'old friends' hypothesis. Clin. Exp. Immunol. 160, 70-79 (2010).
    • (2010) Clin. Exp. Immunol. , vol.160 , pp. 70-79
    • Rook, G.A.1
  • 45
    • 14544275997 scopus 로고    scopus 로고
    • Origins and evolution of the Western diet: Health implications for the 21st century
    • Cordain, L. et al. Origins and evolution of the Western diet: health implications for the 21st century. Am. J. Clin. Nutr. 81, 341-354 (2005).
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 341-354
    • Cordain, L.1
  • 46
    • 84866948370 scopus 로고    scopus 로고
    • Evidence for dietary change but not landscape use in South African early hominins
    • Balter, V., Braga, J., Telouk, P. & Thackeray, J. F. Evidence for dietary change but not landscape use in South African early hominins. Nature 489, 558-560 (2012).
    • (2012) Nature , vol.489 , pp. 558-560
    • Balter, V.1    Braga, J.2    Telouk, P.3    Thackeray, J.F.4
  • 48
    • 80054096785 scopus 로고    scopus 로고
    • The diets of early hominins
    • Ungar, P. S. & Sponheimer, M. The diets of early hominins. Science 334, 190-193 (2011).
    • (2011) Science , vol.334 , pp. 190-193
    • Ungar, P.S.1    Sponheimer, M.2
  • 49
    • 33846078440 scopus 로고    scopus 로고
    • Why do African Americans get more colon cancer than Native Africans
    • O'Keefe, S. J. et al. Why do African Americans get more colon cancer than Native Africans J. Nutr. 137, 175S-182S (2007).
    • (2007) J. Nutr. , vol.137 , pp. 175S-182S
    • O'Keefe, S.J.1
  • 50
    • 84929094853 scopus 로고    scopus 로고
    • Fat, fibre and cancer risk in African Americans and rural Africans
    • O'Keefe, S. J. et al. Fat, fibre and cancer risk in African Americans and rural Africans. Nat. Commun. 6, 6342 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 6342
    • O'Keefe, S.J.1
  • 51
    • 84879456755 scopus 로고    scopus 로고
    • Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans
    • Ou, J. et al. Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans. Am. J. Clin. Nutr. 98, 111-120 (2013).
    • (2013) Am. J. Clin. Nutr. , vol.98 , pp. 111-120
    • Ou, J.1
  • 52
    • 0022606848 scopus 로고
    • Starch utilization by the human large intestinal microflora
    • Macfarlane, G. T. & Englyst, H. N. Starch utilization by the human large intestinal microflora. J. Appl. Bacteriol. 60, 195-201 (1986).
    • (1986) J. Appl. Bacteriol. , vol.60 , pp. 195-201
    • MacFarlane, G.T.1    Englyst, H.N.2
  • 53
    • 0026586542 scopus 로고
    • Comparison of fermentation reactions in different regions of the human colon
    • Macfarlane, G. T., Gibson, G. R. & Cummings, J. H. Comparison of fermentation reactions in different regions of the human colon. J. Appl. Bacteriol. 72, 57-64 (1992).
    • (1992) J. Appl. Bacteriol. , vol.72 , pp. 57-64
    • MacFarlane, G.T.1    Gibson, G.R.2    Cummings, J.H.3
  • 54
    • 0030032123 scopus 로고    scopus 로고
    • Digestion and physiological properties of resistant starch in the human large bowel
    • Cummings, J. H., Beatty, E. R., Kingman, S. M., Bingham, S. A. & Englyst, H. N. Digestion and physiological properties of resistant starch in the human large bowel. Br. J. Nutr. 75, 733-747 (1996).
    • (1996) Br. J. Nutr. , vol.75 , pp. 733-747
    • Cummings, J.H.1    Beatty, E.R.2    Kingman, S.M.3    Bingham, S.A.4    Englyst, H.N.5
  • 55
    • 0019940133 scopus 로고
    • Utilization of nutrients by isolated epithelial cells of the rat colon
    • Roediger, W. E. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology 83, 424-429 (1982).
    • (1982) Gastroenterology , vol.83 , pp. 424-429
    • Roediger, W.E.1
  • 56
    • 84921454304 scopus 로고    scopus 로고
    • Links between diet, gut microbiota composition and gut metabolism
    • Flint, H. J., Duncan, S. H., Scott, K. P. & Louis, P. Links between diet, gut microbiota composition and gut metabolism. Proc. Nutr. Soc. 74, 13-22 (2015).
    • (2015) Proc. Nutr. Soc. , vol.74 , pp. 13-22
    • Flint, H.J.1    Duncan, S.H.2    Scott, K.P.3    Louis, P.4
  • 57
    • 0037509909 scopus 로고    scopus 로고
    • Regulation of short-chain fatty acid production
    • Macfarlane, S. & Macfarlane, G. T. Regulation of short-chain fatty acid production. Proc. Nutr. Soc. 62, 67-72 (2003).
    • (2003) Proc. Nutr. Soc. , vol.62 , pp. 67-72
    • MacFarlane, S.1    MacFarlane, G.T.2
  • 58
    • 85047689124 scopus 로고    scopus 로고
    • Bacteria colonic fermentation, and gastrointestinal health
    • Macfarlane, G. T. & Macfarlane, S. Bacteria, colonic fermentation, and gastrointestinal health. J. AOAC Int. 95, 50-60 (2012).
    • (2012) J. AOAC Int. , vol.95 , pp. 50-60
    • MacFarlane, G.T.1    MacFarlane, S.2
  • 59
    • 33847233644 scopus 로고    scopus 로고
    • Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
    • Duncan, S. H. et al. Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces. Appl. Environ. Microbiol. 73, 1073-1078 (2007).
    • (2007) Appl. Environ. Microbiol. , vol.73 , pp. 1073-1078
    • Duncan, S.H.1
  • 60
    • 48649087037 scopus 로고    scopus 로고
    • Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon
    • Waldecker, M., Kautenburger, T., Daumann, H., Busch, C. & Schrenk, D. Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colon. J. Nutr. Biochem. 19, 587-593 (2008).
    • (2008) J. Nutr. Biochem. , vol.19 , pp. 587-593
    • Waldecker, M.1    Kautenburger, T.2    Daumann, H.3    Busch, C.4    Schrenk, D.5
  • 61
    • 80054111810 scopus 로고    scopus 로고
    • Fermentation in the human large intestine: Its physiologic consequences and the potential contribution of prebiotics
    • Macfarlane, G. T. & Macfarlane, S. Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics. J. Clin. Gastroenterol. 45, S120-S127 (2011).
    • (2011) J. Clin. Gastroenterol. , vol.45 , pp. S120-S127
    • MacFarlane, G.T.1    MacFarlane, S.2
  • 62
    • 84899892790 scopus 로고    scopus 로고
    • The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism
    • Frost, G. et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat. Commun. 5, 3611 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 3611
    • Frost, G.1
  • 63
    • 78650179808 scopus 로고    scopus 로고
    • Biological effects of propionic acid in humans; Metabolism, potential applications and underlying mechanisms
    • Al-Lahham, S. H., Peppelenbosch, M. P., Roelofsen, H., Vonk, R. J. & Venema, K. Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. Biochim. Biophys. Acta 1801, 1175-1183 (2010).
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 1175-1183
    • Al-Lahham, S.H.1    Peppelenbosch, M.P.2    Roelofsen, H.3    Vonk, R.J.4    Venema, K.5
  • 64
    • 0025360099 scopus 로고
    • Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers
    • Venter, C. S., Vorster, H. H. & Cummings, J. H. Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers. Am. J. Gastroenterol. 85, 549-553 (1990).
    • (1990) Am. J. Gastroenterol. , vol.85 , pp. 549-553
    • Venter, C.S.1    Vorster, H.H.2    Cummings, J.H.3
  • 65
    • 84941879755 scopus 로고    scopus 로고
    • Short-chain fatty acids in control of body weight and insulin sensitivity
    • Canfora, E. E., Jocken, J. W. & Blaak, E. E. Short-chain fatty acids in control of body weight and insulin sensitivity. Nat. Rev. Endocrinol. 11, 577-591 (2015).
    • (2015) Nat. Rev. Endocrinol. , vol.11 , pp. 577-591
    • Canfora, E.E.1    Jocken, J.W.2    Blaak, E.E.3
  • 66
    • 0029897422 scopus 로고    scopus 로고
    • Importance of colonic support for energy absorption as small-bowel failure proceeds
    • Nordgaard, I., Hansen, B. S. & Mortensen, P. B. Importance of colonic support for energy absorption as small-bowel failure proceeds. Am. J. Clin. Nutr. 64, 222-231 (1996).
    • (1996) Am. J. Clin. Nutr. , vol.64 , pp. 222-231
    • Nordgaard, I.1    Hansen, B.S.2    Mortensen, P.B.3
  • 67
    • 0028841956 scopus 로고
    • Does digestibility of meat protein help explain large bowel cancer risk
    • Silvester, K. R. & Cummings, J. H. Does digestibility of meat protein help explain large bowel cancer risk Nutr. Cancer 24, 279-288 (1995).
    • (1995) Nutr. Cancer , vol.24 , pp. 279-288
    • Silvester, K.R.1    Cummings, J.H.2
  • 68
    • 84855310228 scopus 로고    scopus 로고
    • Relevance of protein fermentation to gut health
    • Windey, K., De Preter, V. & Verbeke, K. Relevance of protein fermentation to gut health. Mol. Nutr. Food Res. 56, 184-196 (2012).
    • (2012) Mol. Nutr. Food Res. , vol.56 , pp. 184-196
    • Windey, K.1    De Preter, V.2    Verbeke, K.3
  • 69
    • 84948845104 scopus 로고    scopus 로고
    • Production of butyrate from lysine and the Amadori product fructoselysine by a human gut commensal
    • Bui, T. P. et al. Production of butyrate from lysine and the Amadori product fructoselysine by a human gut commensal. Nat. Commun. 6, 10062 (2015).
    • (2015) Nat. Commun. , vol.6 , pp. 10062
    • Bui, T.P.1
  • 70
    • 0018070611 scopus 로고
    • Diet and cell growth modulation by ammonia
    • Visek, W. J. Diet and cell growth modulation by ammonia. Am. J. Clin. Nutr. 31, S216-S220 (1978).
    • (1978) Am. J. Clin. Nutr. , vol.31 , pp. S216-S220
    • Visek, W.J.1
  • 71
    • 0023918030 scopus 로고
    • Effects of ammonium acetate and sodium cholate on N-methyl-N-nitro-N-nitrosoguanidine-induced colon carcinogenesis of rats
    • Clinton, S. K., Bostwick, D. G., Olson, L. M., Mangian, H. J. & Visek, W. J. Effects of ammonium acetate and sodium cholate on N-methyl-N-nitro-N-nitrosoguanidine-induced colon carcinogenesis of rats. Cancer Res. 48, 3035-3039 (1988).
    • (1988) Cancer Res. , vol.48 , pp. 3035-3039
    • Clinton, S.K.1    Bostwick, D.G.2    Olson, L.M.3    Mangian, H.J.4    Visek, W.J.5
  • 72
    • 0029071838 scopus 로고
    • Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC
    • Mirvish, S. S. Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC. Cancer Lett. 93, 17-48 (1995).
    • (1995) Cancer Lett. , vol.93 , pp. 17-48
    • Mirvish, S.S.1
  • 73
    • 3242794269 scopus 로고    scopus 로고
    • Meat-related mutagens/carcinogens in the etiology of colorectal cancer
    • Cross, A. J. & Sinha, R. Meat-related mutagens/carcinogens in the etiology of colorectal cancer. Environ. Mol. Mutagen. 44, 44-55 (2004).
    • (2004) Environ. Mol. Mutagen. , vol.44 , pp. 44-55
    • Cross, A.J.1    Sinha, R.2
  • 74
    • 0029959961 scopus 로고    scopus 로고
    • Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer
    • Bingham, S. A. et al. Does increased endogenous formation of N-nitroso compounds in the human colon explain the association between red meat and colon cancer Carcinogenesis 17, 515-523 (1996).
    • (1996) Carcinogenesis , vol.17 , pp. 515-523
    • Bingham, S.A.1
  • 75
    • 84863436944 scopus 로고    scopus 로고
    • Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10/mice
    • Devkota, S. et al. Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10/mice. Nature. 487, 104-108 (2012).
    • (2012) Nature , vol.487 , pp. 104-108
    • Devkota, S.1
  • 77
    • 67651001726 scopus 로고    scopus 로고
    • Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats
    • Wallace, J. L., Vong, L., McKnight, W., Dicay, M. & Martin, G. R. Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats. Gastroenterology 137, 569-578, (2009).
    • (2009) Gastroenterology , vol.137 , pp. 569-578
    • Wallace, J.L.1    Vong, L.2    McKnight, W.3    Dicay, M.4    Martin, G.R.5
  • 78
    • 84979742634 scopus 로고    scopus 로고
    • Hydrogen sulfide-releasing anti-inflammatory drugs for chemoprevention and treatment of cancer
    • Ianaro, A., Cirino, G. & Wallace, J. L. Hydrogen sulfide-releasing anti-inflammatory drugs for chemoprevention and treatment of cancer. Pharmacol. Res. 111, 652-658 (2016).
    • (2016) Pharmacol. Res. , vol.111 , pp. 652-658
    • Ianaro, A.1    Cirino, G.2    Wallace, J.L.3
  • 79
    • 84907599036 scopus 로고    scopus 로고
    • Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer
    • Elsheikh, W., Blackler, R. W., Flannigan, K. L. & Wallace, J. L. Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer. Nitric Oxide 41, 131-137 (2014).
    • (2014) Nitric Oxide , vol.41 , pp. 131-137
    • Elsheikh, W.1    Blackler, R.W.2    Flannigan, K.L.3    Wallace, J.L.4
  • 80
    • 84869228196 scopus 로고    scopus 로고
    • Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis
    • De Preter, V. et al. Decreased mucosal sulfide detoxification is related to an impaired butyrate oxidation in ulcerative colitis. Inflamm. Bowel Dis. 18, 2371-2380 (2012).
    • (2012) Inflamm. Bowel Dis. , vol.18 , pp. 2371-2380
    • De Preter, V.1
  • 81
    • 70350029623 scopus 로고    scopus 로고
    • Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization
    • McCall, I. C. et al. Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization. Toxicol. Appl. Pharmacol. 241, 61-70 (2009).
    • (2009) Toxicol. Appl. Pharmacol. , vol.241 , pp. 61-70
    • McCall, I.C.1
  • 82
    • 0029883793 scopus 로고    scopus 로고
    • Resistant starch lowers fecal concentrations of ammonia and phenols in humans
    • Birkett, A., Muir, J., Phillips, J., Jones, G. & O'Dea, K. Resistant starch lowers fecal concentrations of ammonia and phenols in humans. Am. J. Clin. Nutr. 63, 766-772 (1996).
    • (1996) Am. J. Clin. Nutr. , vol.63 , pp. 766-772
    • Birkett, A.1    Muir, J.2    Phillips, J.3    Jones, G.4    O'Dea, K.5
  • 83
    • 6944251246 scopus 로고    scopus 로고
    • The in vivo use of the stable isotope-labelled biomarkers lactose-[15N]ureide and [2H4]tyrosine to assess the effects of pro-and prebiotics on the intestinal flora of healthy human volunteers
    • De Preter, V. et al. The in vivo use of the stable isotope-labelled biomarkers lactose-[15N]ureide and [2H4]tyrosine to assess the effects of pro-and prebiotics on the intestinal flora of healthy human volunteers. Br. J. Nutr. 92, 439-446 (2004).
    • (2004) Br. J. Nutr. , vol.92 , pp. 439-446
    • De Preter, V.1
  • 84
    • 33846878508 scopus 로고    scopus 로고
    • Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients
    • Rafter, J. et al. Dietary synbiotics reduce cancer risk factors in polypectomized and colon cancer patients. Am. J. Clin. Nutr. 85, 488-496 (2007).
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 488-496
    • Rafter, J.1
  • 85
    • 84905859180 scopus 로고    scopus 로고
    • Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: A randomized trial
    • Humphreys, K. J. et al. Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: a randomized trial. Cancer Prev. Res. (Phila. ) 7, 786-795 (2014).
    • (2014) Cancer Prev. Res. (Phila. ) , vol.7 , pp. 786-795
    • Humphreys, K.J.1
  • 86
    • 84945237892 scopus 로고    scopus 로고
    • Butyrate inhibits pro-proliferative MIR-92a by diminishing c-Myc-induced MIR-17-92a cluster transcription in human colon cancer cells
    • Hu, S., Liu, L., Chang, E. B., Wang, J. Y. & Raufman, J. P. Butyrate inhibits pro-proliferative miR-92a by diminishing c-Myc-induced miR-17-92a cluster transcription in human colon cancer cells. Mol. Cancer 14, 180 (2015).
    • (2015) Mol. Cancer , vol.14 , pp. 180
    • Hu, S.1    Liu, L.2    Chang, E.B.3    Wang, J.Y.4    Raufman, J.P.5
  • 87
    • 84876920542 scopus 로고    scopus 로고
    • Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma
    • Chen, H. M. et al. Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma. Am. J. Clin. Nutr. 97, 1044-1052 (2013).
    • (2013) Am. J. Clin. Nutr. , vol.97 , pp. 1044-1052
    • Chen, H.M.1
  • 88
    • 84855923925 scopus 로고    scopus 로고
    • Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
    • Wang, T. et al. Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers. ISME J. 6, 320-329 (2012).
    • (2012) ISME J. , vol.6 , pp. 320-329
    • Wang, T.1
  • 89
    • 84872677660 scopus 로고    scopus 로고
    • The microbiota and its metabolites in colonic mucosal health and cancer risk
    • Vipperla, K. & O'Keefe, S. J. The microbiota and its metabolites in colonic mucosal health and cancer risk. Nutr. Clin. Pract. 27, 624-635 (2012).
    • (2012) Nutr. Clin. Pract. , vol.27 , pp. 624-635
    • Vipperla, K.1    O'Keefe, S.J.2
  • 90
    • 0036846899 scopus 로고    scopus 로고
    • Dietary fiber down-regulates colonic tumor necrosis factor and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats
    • Rodriguez-Cabezas, M. E. et al. Dietary fiber down-regulates colonic tumor necrosis factor and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. J. Nutr. 132, 3263-3271 (2002).
    • (2002) J. Nutr. , vol.132 , pp. 3263-3271
    • Rodriguez-Cabezas, M.E.1
  • 91
    • 0034062353 scopus 로고    scopus 로고
    • The luminal short-chain fatty acid butyrate modulates NF-kB activity in a human colonic epithelial cell line
    • Inan, M. S. et al. The luminal short-chain fatty acid butyrate modulates NF-kB activity in a human colonic epithelial cell line. Gastroenterology 118, 724-734 (2000).
    • (2000) Gastroenterology , vol.118 , pp. 724-734
    • Inan, M.S.1
  • 92
    • 33751093301 scopus 로고    scopus 로고
    • Upregulation of BAK by butyrate in the colon is associated with increased Sp3 binding
    • Chirakkal, H. et al. Upregulation of BAK by butyrate in the colon is associated with increased Sp3 binding. Oncogene 25, 7192-7200 (2006).
    • (2006) Oncogene , vol.25 , pp. 7192-7200
    • Chirakkal, H.1
  • 93
    • 0036252352 scopus 로고    scopus 로고
    • The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation
    • Hinnebusch, B. F., Meng, S., Wu, J. T., Archer, S. Y. & Hodin, R. A. The effects of short-chain fatty acids on human colon cancer cell phenotype are associated with histone hyperacetylation. J. Nutr. 132, 1012-1017 (2002).
    • (2002) J. Nutr. , vol.132 , pp. 1012-1017
    • Hinnebusch, B.F.1    Meng, S.2    Wu, J.T.3    Archer, S.Y.4    Hodin, R.A.5
  • 94
    • 33745301716 scopus 로고    scopus 로고
    • The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype
    • Comalada, M. et al. The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype. J. Cancer Res. Clin. Oncol. 132, 487-497 (2006).
    • (2006) J. Cancer Res. Clin. Oncol. , vol.132 , pp. 487-497
    • Comalada, M.1
  • 95
    • 0035712906 scopus 로고    scopus 로고
    • Sodium butyrate enhances complement-mediated cell injury via down-regulation of decay-accelerating factor expression in colonic cancer cells
    • Andoh, A., Shimada, M., Araki, Y., Fujiyama, Y. & Bamba, T. Sodium butyrate enhances complement-mediated cell injury via down-regulation of decay-accelerating factor expression in colonic cancer cells. Cancer Immunol. Immunother. 50, 663-672 (2002).
    • (2002) Cancer Immunol. Immunother. , vol.50 , pp. 663-672
    • Andoh, A.1    Shimada, M.2    Araki, Y.3    Fujiyama, Y.4    Bamba, T.5
  • 96
    • 26244457666 scopus 로고    scopus 로고
    • Effect of sodium butyrate on pro-matrix metalloproteinase-9 and-2 differential secretion in pediatric tumors and cell lines
    • Rodrguez-Salvador, J. et al. Effect of sodium butyrate on pro-matrix metalloproteinase-9 and-2 differential secretion in pediatric tumors and cell lines. J. Exp. Clin. Cancer Res. 24, 463-473 (2005).
    • (2005) J. Exp. Clin. Cancer Res. , vol.24 , pp. 463-473
    • Rodrguez-Salvador, J.1
  • 97
    • 13244255231 scopus 로고    scopus 로고
    • Prolonged butyrate treatment inhibits the migration and invasion potential of HT1080 tumor cells
    • Zeng, H. & Briske-Anderson, M. Prolonged butyrate treatment inhibits the migration and invasion potential of HT1080 tumor cells. J. Nutr. 135, 291-295 (2005).
    • (2005) J. Nutr. , vol.135 , pp. 291-295
    • Zeng, H.1    Briske-Anderson, M.2
  • 98
    • 0037462884 scopus 로고    scopus 로고
    • Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1 nuclear translocation
    • Zgouras, D., Wachtershauser, A., Frings, D. & Stein, J. Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-1 nuclear translocation. Biochem. Biophys. Res. Commun. 300, 832-838 (2003).
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 832-838
    • Zgouras, D.1    Wachtershauser, A.2    Frings, D.3    Stein, J.4
  • 99
    • 0141645569 scopus 로고    scopus 로고
    • Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E1 and E2 production by intestinal myofibroblasts
    • Willemsen, L. E., Koetsier, M. A., van Deventer, S. J. & van Tol, E. A. Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E1 and E2 production by intestinal myofibroblasts. Gut 52, 1442-1447 (2003).
    • (2003) Gut , vol.52 , pp. 1442-1447
    • Willemsen, L.E.1    Koetsier, M.A.2    Van Deventer, S.J.3    Van Tol, E.A.4
  • 100
    • 0029924943 scopus 로고    scopus 로고
    • Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model
    • D'Argenio, G. et al. Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. Gastroenterology 110, 1727-1734 (1996).
    • (1996) Gastroenterology , vol.110 , pp. 1727-1734
    • D'Argenio, G.1
  • 101
    • 0038523850 scopus 로고    scopus 로고
    • Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: Relevance of signalling pathways
    • Schauber, J. et al. Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways. Gut 52, 735-741 (2003).
    • (2003) Gut , vol.52 , pp. 735-741
    • Schauber, J.1
  • 102
    • 21344468601 scopus 로고    scopus 로고
    • Anti-inflammatory properties of heat shock protein 70 and butyrate on Salmonella-induced interleukin-8 secretion in enterocyte-like Caco-2 cells
    • Malago, J. J., Koninkx, J. F., Tooten, P. C., van Liere, E. A. & van Dijk, J. E. Anti-inflammatory properties of heat shock protein 70 and butyrate on Salmonella-induced interleukin-8 secretion in enterocyte-like Caco-2 cells. Clin. Exp. Immunol. 141, 62-71 (2005).
    • (2005) Clin. Exp. Immunol. , vol.141 , pp. 62-71
    • Malago, J.J.1    Koninkx, J.F.2    Tooten, P.C.3    Van Liere, E.A.4    Van Dijk, J.E.5
  • 103
    • 84881068658 scopus 로고    scopus 로고
    • The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
    • Smith, P. M. et al. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 341, 569-573 (2013).
    • (2013) Science , vol.341 , pp. 569-573
    • Smith, P.M.1
  • 104
    • 79251644886 scopus 로고    scopus 로고
    • The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer
    • Hu, S. et al. The microbe-derived short chain fatty acid butyrate targets miRNA-dependent p21 gene expression in human colon cancer. PLoS ONE 6, e16221 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e16221
    • Hu, S.1
  • 105
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He, L. et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005).
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1
  • 106
    • 80051574976 scopus 로고    scopus 로고
    • MicroRNA (miRNA) expression is regulated by butyrate-induced epigenetic modulation of gene expression in bovine cells
    • Li, C.-J., Li, R. W. & Elsasser, T. H. MicroRNA (miRNA) expression is regulated by butyrate-induced epigenetic modulation of gene expression in bovine cells. Genet. Epigenet. 3, 23-32 (2010).
    • (2010) Genet. Epigenet. , vol.3 , pp. 23-32
    • Li, C.-J.1    Li, R.W.2    Elsasser, T.H.3
  • 107
    • 84876425427 scopus 로고    scopus 로고
    • Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic MIR-17-92 cluster
    • Humphreys, K. J., Cobiac, L., Le Leu, R. K., Van der Hoek, M. B. & Michael, M. Z. Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Mol. Carcinog. 52, 459-474 (2013).
    • (2013) Mol. Carcinog. , vol.52 , pp. 459-474
    • Humphreys, K.J.1    Cobiac, L.2    Le Leu, R.K.3    Van Der Hoek, M.B.4    Michael, M.Z.5
  • 109
    • 84870389262 scopus 로고    scopus 로고
    • The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation
    • Donohoe, D. R. et al. The Warburg effect dictates the mechanism of butyrate-mediated histone acetylation and cell proliferation. Mol. Cell 48, 612-626 (2012).
    • (2012) Mol. Cell , vol.48 , pp. 612-626
    • Donohoe, D.R.1
  • 110
    • 84911993839 scopus 로고    scopus 로고
    • A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner
    • Donohoe, D. R. et al. A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota-and butyrate-dependent manner. Cancer Discov. 4, 1387-1397 (2014).
    • (2014) Cancer Discov. , vol.4 , pp. 1387-1397
    • Donohoe, D.R.1
  • 111
    • 84904543667 scopus 로고    scopus 로고
    • Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells
    • Belcheva, A. et al. Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells. Cell 158, 288-299 (2014).
    • (2014) Cell , vol.158 , pp. 288-299
    • Belcheva, A.1
  • 112
    • 84957561694 scopus 로고    scopus 로고
    • Grain-rich diets altered the colonic fermentation and mucosa-associated bacterial communities and induced mucosal injuries in goats
    • Ye, H., Liu, J., Feng, P., Zhu, W. & Mao, S. Grain-rich diets altered the colonic fermentation and mucosa-associated bacterial communities and induced mucosal injuries in goats. Sci. Rep. 6, 20329 (2016).
    • (2016) Sci. Rep. , vol.6 , pp. 20329
    • Ye, H.1    Liu, J.2    Feng, P.3    Zhu, W.4    Mao, S.5
  • 113
    • 79960979008 scopus 로고    scopus 로고
    • Ruminant Nutrition Symposium: Productivity, digestion, and health responses to hindgut acidosis in ruminants
    • Gressley, T. F., Hall, M. B. & Armentano, L. E. Ruminant Nutrition Symposium: productivity, digestion, and health responses to hindgut acidosis in ruminants. J. Anim. Sci. 89, 1120-1130 (2011).
    • (2011) J. Anim. Sci. , vol.89 , pp. 1120-1130
    • Gressley, T.F.1    Hall, M.B.2    Armentano, L.E.3
  • 114
    • 84929379493 scopus 로고    scopus 로고
    • D-lactic acidosis: An underrecognized complication of short bowel syndrome
    • Kowlgi, N. G. & Chhabra, L. D-lactic acidosis: an underrecognized complication of short bowel syndrome. Gastroenterol. Res. Pract. 2015, 476215 (2015).
    • (2015) Gastroenterol. Res. Pract. , vol.2015 , pp. 476215
    • Kowlgi, N.G.1    Chhabra, L.2
  • 115
    • 81555222582 scopus 로고    scopus 로고
    • Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon
    • Winter, J. et al. Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon. Cancer Prev. Res. (Phila. ) 4, 1920-1928 (2011).
    • (2011) Cancer Prev. Res. (Phila. ) , vol.4 , pp. 1920-1928
    • Winter, J.1
  • 116
    • 33646417960 scopus 로고    scopus 로고
    • Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats
    • Toden, S., Bird, A. R., Topping, D. L. & Conlon, M. A. Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats. Cancer Biol. Ther. 5, 267-272 (2006).
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 267-272
    • Toden, S.1    Bird, A.R.2    Topping, D.L.3    Conlon, M.A.4
  • 117
    • 34047257837 scopus 로고    scopus 로고
    • Differential effects of dietary whey, casein and soya on colonic DNA damage and large bowel SCFA in rats fed diets low and high in resistant starch
    • Toden, S., Bird, A. R., Topping, D. L. & Conlon, M. A. Differential effects of dietary whey, casein and soya on colonic DNA damage and large bowel SCFA in rats fed diets low and high in resistant starch. Br. J. Nutr. 97, 535-543 (2007).
    • (2007) Br. J. Nutr. , vol.97 , pp. 535-543
    • Toden, S.1    Bird, A.R.2    Topping, D.L.3    Conlon, M.A.4
  • 118
    • 0031975481 scopus 로고    scopus 로고
    • Effects of resistant starch on the colon in healthy volunteers: Possible implications for cancer prevention
    • Hylla, S. et al. Effects of resistant starch on the colon in healthy volunteers: possible implications for cancer prevention. Am. J. Clin. Nutr. 67, 136-142 (1998).
    • (1998) Am. J. Clin. Nutr. , vol.67 , pp. 136-142
    • Hylla, S.1
  • 119
    • 0028314302 scopus 로고
    • Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation
    • van Munster, I. P., Tangerman, A. & Nagengast, F. M. Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation. Dig. Dis. Sci. 39, 834-842 (1994).
    • (1994) Dig. Dis. Sci. , vol.39 , pp. 834-842
    • Van Munster, I.P.1    Tangerman, A.2    Nagengast, F.M.3
  • 120
    • 68749119436 scopus 로고    scopus 로고
    • Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre
    • Scharlau, D. et al. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat. Res. 682, 39-53 (2009).
    • (2009) Mutat. Res. , vol.682 , pp. 39-53
    • Scharlau, D.1
  • 122
    • 79955383693 scopus 로고    scopus 로고
    • High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health
    • Russell, W. R. et al. High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health. Am. J. Clin. Nutr. 93, 1062-1072 (2011).
    • (2011) Am. J. Clin. Nutr. , vol.93 , pp. 1062-1072
    • Russell, W.R.1
  • 123
    • 84924565327 scopus 로고    scopus 로고
    • A survey of modulation of gut microbiota by dietary polyphenols
    • Dueas, M. et al. A survey of modulation of gut microbiota by dietary polyphenols. Biomed. Res. Int. 2015, 850902 (2015).
    • (2015) Biomed. Res. Int. , vol.2015 , pp. 850902
    • Dueas, M.1
  • 124
    • 78049512483 scopus 로고    scopus 로고
    • Novel approaches for analysing gut microbes and dietary polyphenols: Challenges and opportunities
    • Kemperman, R. A., Bolca, S., Roger, L. C. & Vaughan, E. E. Novel approaches for analysing gut microbes and dietary polyphenols: challenges and opportunities. Microbiology 156, 3224-3231 (2010).
    • (2010) Microbiology , vol.156 , pp. 3224-3231
    • Kemperman, R.A.1    Bolca, S.2    Roger, L.C.3    Vaughan, E.E.4
  • 125
    • 79955017875 scopus 로고    scopus 로고
    • Molecular binding of black tea theaflavins to biological membranes: Relationship to bioactivities
    • Sirk, T. W., Friedman, M. & Brown, E. F. Molecular binding of black tea theaflavins to biological membranes: relationship to bioactivities. J. Agric. Food Chem. 59, 3780-3787 (2011).
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 3780-3787
    • Sirk, T.W.1    Friedman, M.2    Brown, E.F.3
  • 127
    • 84944096442 scopus 로고    scopus 로고
    • Impact of palm date consumption on microbiota growth and large intestinal health: A randomised, controlled, cross-over, human intervention study
    • Eid, N. et al. Impact of palm date consumption on microbiota growth and large intestinal health: a randomised, controlled, cross-over, human intervention study. Br. J. Nutr. 114, 1226-1236 (2015).
    • (2015) Br. J. Nutr. , vol.114 , pp. 1226-1236
    • Eid, N.1
  • 128
    • 84962281072 scopus 로고    scopus 로고
    • In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: A new potentiality for ellagitannin metabolites against cancer
    • Nuez-Snchez, M. A. et al. In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: a new potentiality for ellagitannin metabolites against cancer. Food Chem. Toxicol. 92, 8-16 (2016).
    • (2016) Food Chem. Toxicol. , vol.92 , pp. 8-16
    • Nuez-Snchez, M.A.1
  • 129
    • 84866381930 scopus 로고    scopus 로고
    • Intestinal ellagitannin metabolites ameliorate cytokine-induced inflammation and associated molecular markers in human colon fibroblasts
    • Gimnez-Bastida, J. A. et al. Intestinal ellagitannin metabolites ameliorate cytokine-induced inflammation and associated molecular markers in human colon fibroblasts. J. Agric. Food Chem. 60, 8866-8876 (2012).
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 8866-8876
    • Gimnez-Bastida, J.A.1
  • 130
    • 84949991156 scopus 로고    scopus 로고
    • Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: The role of cell metabolism
    • Gonzlez-Sarras, A., Nuez-Snchez, M. A., Garca-Villalba, R., Toms-Barbern, F. A. & Espn, J. C. Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism. Eur. J. Nutr. http://dx. doi. org/10. 1007/s00394-015-1131-7 (2015).
    • (2015) Eur. J. Nutr.
    • Gonzlez-Sarras, A.1    Nuez-Snchez, M.A.2    Garca-Villalba, R.3    Toms-Barbern, F.A.4    Espn, J.C.5
  • 131
    • 84904320624 scopus 로고    scopus 로고
    • A phase Ib study of the effects of black raspberries on rectal polyps in patients with familial adenomatous polyposis
    • Wang, L. S. et al. A phase Ib study of the effects of black raspberries on rectal polyps in patients with familial adenomatous polyposis. Cancer Prev. Res. (Phila. ) 7, 666-674 (2014).
    • (2014) Cancer Prev. Res. (Phila. ) , vol.7 , pp. 666-674
    • Wang, L.S.1
  • 132
    • 34548481540 scopus 로고    scopus 로고
    • Cancer prevention with freeze-dried berries and berry components
    • Stoner, G. D. et al. Cancer prevention with freeze-dried berries and berry components. Semin. Cancer Biol. 17, 403-410 (2007).
    • (2007) Semin. Cancer Biol. , vol.17 , pp. 403-410
    • Stoner, G.D.1
  • 133
    • 84861552107 scopus 로고    scopus 로고
    • Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers
    • Queipo-Ortuno, M. I. et al. Influence of red wine polyphenols and ethanol on the gut microbiota ecology and biochemical biomarkers. Am. J. Clin. Nutr. 95, 1323-1334 (2012).
    • (2012) Am. J. Clin. Nutr. , vol.95 , pp. 1323-1334
    • Queipo-Ortuno, M.I.1
  • 134
    • 84921635559 scopus 로고    scopus 로고
    • Coffee consumption and risk of colorectal cancer: The Japan Collaborative Cohort Study
    • Yamada, H. et al. Coffee consumption and risk of colorectal cancer: the Japan Collaborative Cohort Study. J. Epidemiol. 24, 370-378 (2014).
    • (2014) J. Epidemiol. , vol.24 , pp. 370-378
    • Yamada, H.1
  • 135
    • 84947282178 scopus 로고    scopus 로고
    • Coffee intake, recurrence, and mortality in stage III colon cancer: Results from CALGB 89803 (Alliance)
    • Guercio, B. J. et al. Coffee intake, recurrence, and mortality in stage III colon cancer: results from CALGB 89803 (Alliance). J. Clin. Oncol. 33, 3598-3607 (2015).
    • (2015) J. Clin. Oncol. , vol.33 , pp. 3598-3607
    • Guercio, B.J.1
  • 136
    • 84877315225 scopus 로고    scopus 로고
    • Dietary polyphenols and colorectal cancer risk: The Fukuoka colorectal cancer study
    • Wang, Z. J. et al. Dietary polyphenols and colorectal cancer risk: the Fukuoka colorectal cancer study. World J. Gastroenterol. 19, 2683-2690 (2013).
    • (2013) World J. Gastroenterol. , vol.19 , pp. 2683-2690
    • Wang, Z.J.1
  • 138
    • 84929658789 scopus 로고    scopus 로고
    • Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer
    • Guertin, K. A. et al. Serum biomarkers of habitual coffee consumption may provide insight into the mechanism underlying the association between coffee consumption and colorectal cancer. Am. J. Clin. Nutr. 101, 1000-1011 (2015).
    • (2015) Am. J. Clin. Nutr. , vol.101 , pp. 1000-1011
    • Guertin, K.A.1
  • 139
    • 0025687278 scopus 로고
    • Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women
    • Willett, W. C., Stampfer, M. J., Colditz, G. A., Rosner, B. A. & Speizer, F. E. Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N. Engl. J. Med. 323, 1664-1672 (1990).
    • (1990) N. Engl. J. Med. , vol.323 , pp. 1664-1672
    • Willett, W.C.1    Stampfer, M.J.2    Colditz, G.A.3    Rosner, B.A.4    Speizer, F.E.5
  • 141
    • 84984644975 scopus 로고    scopus 로고
    • High-fat diets rich in dietary saturated fat protect against azoxymethane/dextran sulfate sodium induced colon cancer
    • Enos, R. T. et al. High-fat diets rich in dietary saturated fat protect against azoxymethane/dextran sulfate sodium induced colon cancer. Am. J. Physiol. Gastrointest. Liver Physiol. 310, G906-G919 (2016).
    • (2016) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.310 , pp. G906-G919
    • Enos, R.T.1
  • 142
    • 84931560567 scopus 로고    scopus 로고
    • Dietary and biomarker estimates of fatty acids and risk of colorectal cancer
    • Hodge, A. M. et al. Dietary and biomarker estimates of fatty acids and risk of colorectal cancer. Int. J. Cancer 137, 1224-1234 (2015).
    • (2015) Int. J. Cancer , vol.137 , pp. 1224-1234
    • Hodge, A.M.1
  • 143
    • 84975127398 scopus 로고    scopus 로고
    • Effects of an high-fat diet enriched in lard or in fish oil on the hypothalamic amp-activated protein kinase and inflammatory mediators
    • Viggiano, E. et al. Effects of an high-fat diet enriched in lard or in fish oil on the hypothalamic amp-activated protein kinase and inflammatory mediators. Front. Cell. Neurosci. 10, 150 (2016).
    • (2016) Front. Cell. Neurosci. , vol.10 , pp. 150
    • Viggiano, E.1
  • 144
    • 84960193503 scopus 로고    scopus 로고
    • High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
    • Beyaz, S. et al. High-fat diet enhances stemness and tumorigenicity of intestinal progenitors. Nature 531, 53-58 (2016).
    • (2016) Nature , vol.531 , pp. 53-58
    • Beyaz, S.1
  • 145
    • 77649179672 scopus 로고    scopus 로고
    • Eicosanoids and cancer
    • Wang, D. & Dubois, R. N. Eicosanoids and cancer. Nat. Rev. Cancer 10, 181-193 (2010).
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 181-193
    • Wang, D.1    Dubois, R.N.2
  • 146
    • 0034010274 scopus 로고    scopus 로고
    • Identification and characterization of a bile acid 7-dehydroxylation operon in Clostridium sp strain TO-931, a highly active 7-dehydroxylating strain isolated from human feces
    • Wells, J. E. & Hylemon, P. B. Identification and characterization of a bile acid 7-dehydroxylation operon in Clostridium sp. strain TO-931, a highly active 7-dehydroxylating strain isolated from human feces. Appl. Environ. Microbiol. 66, 1107-1113 (2000).
    • (2000) Appl. Environ. Microbiol. , vol.66 , pp. 1107-1113
    • Wells, J.E.1    Hylemon, P.B.2
  • 147
    • 80052739162 scopus 로고    scopus 로고
    • Carcinogenicity of deoxycholate, a secondary bile acid
    • Bernstein, C. et al. Carcinogenicity of deoxycholate, a secondary bile acid. Arch. Toxicol. 85, 863-871 (2011).
    • (2011) Arch. Toxicol. , vol.85 , pp. 863-871
    • Bernstein, C.1
  • 148
    • 77955914922 scopus 로고    scopus 로고
    • Bile acids are multifunctional modulators of the Barrett's carcinogenesis
    • Burnat, G., Majka, J. & Konturek, P. C. Bile acids are multifunctional modulators of the Barrett's carcinogenesis. J. Physiol. Pharmacol. 61, 185-192 (2010).
    • (2010) J. Physiol. Pharmacol. , vol.61 , pp. 185-192
    • Burnat, G.1    Majka, J.2    Konturek, P.C.3
  • 150
    • 9044253329 scopus 로고    scopus 로고
    • Randomized, double-blinded, placebo-controlled study of effect of wheat bran fiber and calcium on fecal bile acids in patients with resected adenomatous colon polyps
    • Alberts, D. S. et al. Randomized, double-blinded, placebo-controlled study of effect of wheat bran fiber and calcium on fecal bile acids in patients with resected adenomatous colon polyps. J. Natl Cancer Inst. 88, 81-92 (1996).
    • (1996) J. Natl Cancer Inst. , vol.88 , pp. 81-92
    • Alberts, D.S.1
  • 151
    • 0033921581 scopus 로고    scopus 로고
    • Protective effect of the bile salt hydrolase-active Lactobacillus reuteri against bile salt cytotoxicity
    • De Boever, P. et al. Protective effect of the bile salt hydrolase-active Lactobacillus reuteri against bile salt cytotoxicity. Appl. Microbiol. Biotechnol. 53, 709-714 (2000).
    • (2000) Appl. Microbiol. Biotechnol. , vol.53 , pp. 709-714
    • De Boever, P.1
  • 152
    • 84948682506 scopus 로고    scopus 로고
    • Dietary polyphenols increase fecal mucin and immunoglobulin A and ameliorate the disturbance in gut microbiota caused by a high fat diet
    • Taira, T. et al. Dietary polyphenols increase fecal mucin and immunoglobulin A and ameliorate the disturbance in gut microbiota caused by a high fat diet. J. Clin. Biochem. Nutr. 57, 212-216 (2015).
    • (2015) J. Clin. Biochem. Nutr. , vol.57 , pp. 212-216
    • Taira, T.1
  • 153
    • 84979584538 scopus 로고    scopus 로고
    • Protective effect of agaro-oligosaccharides on gut dysbiosis and colon tumorigenesis in high-fat diet-fed mice
    • Higashimura, Y. et al. Protective effect of agaro-oligosaccharides on gut dysbiosis and colon tumorigenesis in high-fat diet-fed mice. Am. J. Physiol. Gastrointest. Liver Physiol. 310, G367-G375 (2016).
    • (2016) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.310 , pp. G367-G375
    • Higashimura, Y.1
  • 154
    • 0029994786 scopus 로고    scopus 로고
    • Effect of amount and types of dietary fat on intestinal bacterial 7-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion
    • Reddy, B. S., Simi, B., Patel, N., Aliaga, C. & Rao, C. V. Effect of amount and types of dietary fat on intestinal bacterial 7-dehydroxylase and phosphatidylinositol-specific phospholipase C and colonic mucosal diacylglycerol kinase and PKC activities during stages of colon tumor promotion. Cancer Res. 56, 2314-2320 (1996).
    • (1996) Cancer Res. , vol.56 , pp. 2314-2320
    • Reddy, B.S.1    Simi, B.2    Patel, N.3    Aliaga, C.4    Rao, C.V.5
  • 155
    • 38349161648 scopus 로고    scopus 로고
    • Westernizing diets influence fat intake, red blood cell fatty acid composition, and health in remote Alaskan Native communities in the Center for Alaska Native Health Study
    • Bersamin, A., Luick, B. R., King, I. B., Stern, J. S. & Zidenberg-Cherr, S. Westernizing diets influence fat intake, red blood cell fatty acid composition, and health in remote Alaskan Native communities in the Center for Alaska Native Health Study. J. Am. Diet. Assoc. 108, 266-273 (2008).
    • (2008) J. Am. Diet. Assoc. , vol.108 , pp. 266-273
    • Bersamin, A.1    Luick, B.R.2    King, I.B.3    Stern, J.S.4    Zidenberg-Cherr, S.5
  • 156
    • 33750284280 scopus 로고    scopus 로고
    • Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: Nutritional implications for chronic diseases
    • Simopoulos, A. P. Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomed. Pharmacother. 60, 502-507 (2006).
    • (2006) Biomed. Pharmacother. , vol.60 , pp. 502-507
    • Simopoulos, A.P.1
  • 157
    • 77952304753 scopus 로고    scopus 로고
    • Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans
    • Kim, S., Sandler, D. P., Galanko, J., Martin, C. & Sandler, R. S. Intake of polyunsaturated fatty acids and distal large bowel cancer risk in whites and African Americans. Am. J. Epidemiol. 171, 969-979 (2010).
    • (2010) Am. J. Epidemiol. , vol.171 , pp. 969-979
    • Kim, S.1    Sandler, D.P.2    Galanko, J.3    Martin, C.4    Sandler, R.S.5
  • 158
    • 78049287658 scopus 로고    scopus 로고
    • Dietary fish oil alters T lymphocyte cell populations and exacerbates disease in a mouse model of inflammatory colitis
    • Woodworth, H. L. et al. Dietary fish oil alters T lymphocyte cell populations and exacerbates disease in a mouse model of inflammatory colitis. Cancer Res. 70, 7960-7969 (2010).
    • (2010) Cancer Res. , vol.70 , pp. 7960-7969
    • Woodworth, H.L.1
  • 159
    • 73349119392 scopus 로고    scopus 로고
    • Fish oil ingestion reduces the number of aberrant crypt foci and adenoma in 1, 2-dimethylhydrazine-induced colon cancer in rats
    • Moreira, A. P. B. et al. Fish oil ingestion reduces the number of aberrant crypt foci and adenoma in 1, 2-dimethylhydrazine-induced colon cancer in rats. Braz. J. Med. Biol. Res. 42, 1167-1172 (2009).
    • (2009) Braz. J. Med. Biol. Res. , vol.42 , pp. 1167-1172
    • Moreira, A.P.B.1
  • 161
    • 13844266089 scopus 로고    scopus 로고
    • Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells
    • Hofmanov, J., Vaculov, A., Lojek, A. & Kozubk, A. Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells. Eur. J. Nutr. 44, 40-51 (2005).
    • (2005) Eur. J. Nutr. , vol.44 , pp. 40-51
    • Hofmanov, J.1    Vaculov, A.2    Lojek, A.3    Kozubk, A.4
  • 162
    • 36148957839 scopus 로고    scopus 로고
    • Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca2+ accumulation in colonocytes
    • Kolar, S. S. N. et al. Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca2+ accumulation in colonocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G935-G943 (2007).
    • (2007) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.293 , pp. G935-G943
    • Kolar, S.S.N.1
  • 165
    • 84941935477 scopus 로고    scopus 로고
    • Obesity as a risk factor in cancer: A national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology
    • Goday, A. et al. Obesity as a risk factor in cancer: a national consensus of the Spanish Society for the Study of Obesity and the Spanish Society of Medical Oncology. Clin. Transl Oncol. 17, 763-771 (2015).
    • (2015) Clin. Transl Oncol. , vol.17 , pp. 763-771
    • Goday, A.1
  • 166
    • 84964000638 scopus 로고    scopus 로고
    • Changes seen in gut bacteria content and distribution with obesity: Causation or association
    • Bell, D. S. Changes seen in gut bacteria content and distribution with obesity: causation or association Postgrad. Med. 127, 863-868 (2015).
    • (2015) Postgrad. Med. , vol.127 , pp. 863-868
    • Bell, D.S.1
  • 167
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Turnbaugh, P. et al. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature 444, 1027-1031 (2006).
    • (2006) Nature , vol.444 , pp. 1027-1031
    • Turnbaugh, P.1
  • 168
    • 73949137604 scopus 로고    scopus 로고
    • Microbiota and SCFA in lean and overweight healthy subjects
    • Schwiertz, A. et al. Microbiota and SCFA in lean and overweight healthy subjects. Obesity 18, 190-195 (2009).
    • (2009) Obesity , vol.18 , pp. 190-195
    • Schwiertz, A.1
  • 169
    • 84976274744 scopus 로고    scopus 로고
    • The gut microbiome and obesity
    • John, G. K. & Mullin, G. E. The gut microbiome and obesity. Curr. Oncol. Rep. 18, 45 (2016).
    • (2016) Curr. Oncol. Rep. , vol.18 , pp. 45
    • John, G.K.1    Mullin, G.E.2
  • 170
    • 85019799156 scopus 로고    scopus 로고
    • Sa1465 Obesity and colon cancer risk: Is it the fat
    • Ou, J. et al. Sa1465 Obesity and colon cancer risk: is it the fat Gastroenterology 142, S-313 (2012).
    • (2012) Gastroenterology , vol.142 , pp. S-313
    • Ou, J.1
  • 171
    • 0038479410 scopus 로고    scopus 로고
    • Dietary fibre for the prevention of colorectal adenomas and carcinomas
    • Asano, T. K. & McLeod, R. S. Dietary fibre for the prevention of colorectal adenomas and carcinomas. Cochrane Database Syst. Rev. 2, CD003430 (2002).
    • (2002) Cochrane Database Syst. Rev. , vol.2 , pp. CD003430
    • Asano, T.K.1    McLeod, R.S.2
  • 172
    • 0034690234 scopus 로고    scopus 로고
    • Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas
    • Schatzkin, A. et al. Lack of effect of a low-fat, high-fiber diet on the recurrence of colorectal adenomas. N. Engl. J. Med. 342, 1149-1155 (2000).
    • (2000) N. Engl. J. Med. , vol.342 , pp. 1149-1155
    • Schatzkin, A.1
  • 173
    • 0015543957 scopus 로고
    • Diseases of the alimentary tract and western diets
    • Burkitt, D. P. Diseases of the alimentary tract and western diets. Pathol. Microbiol. (Basel) 39, 177-186 (1971).
    • (1971) Pathol. Microbiol. (Basel) , vol.39 , pp. 177-186
    • Burkitt, D.P.1
  • 174
    • 33745667322 scopus 로고    scopus 로고
    • High dry bean intake and reduced risk of advanced colorectal adenoma recurrence among participants in the polyp prevention trial
    • Lanza, E. et al. High dry bean intake and reduced risk of advanced colorectal adenoma recurrence among participants in the polyp prevention trial. J. Nutr. 136, 1896-1903 (2006).
    • (2006) J. Nutr. , vol.136 , pp. 1896-1903
    • Lanza, E.1
  • 175
    • 55949098392 scopus 로고    scopus 로고
    • Position of the American Dietetic Association: Health implications of dietary fiber
    • Slavin, J. L. Position of the American Dietetic Association: health implications of dietary fiber. J. Am. Diet Assoc. 108, 1716-1731 (2008).
    • (2008) J. Am. Diet Assoc. , vol.108 , pp. 1716-1731
    • Slavin, J.L.1
  • 176
    • 84966611782 scopus 로고    scopus 로고
    • U. S. Department of Health and Human Services and U. S. Department of Agriculture
    • U. S. Department of Health and Human Services and U. S. Department of Agriculture. 2015-2020 Dietary Guidelines for Americans. 8th Edition. http://health. gov/dietaryguidelines/2015/guidelines/(2015).
    • (2015) 2015-2020 Dietary Guidelines for Americans. 8th Edition
  • 177
    • 84944685213 scopus 로고    scopus 로고
    • Scientific Advisory Committee on Nutrition
    • Scientific Advisory Committee on Nutrition. SACN Carbohydrates and Health Report. https://www. gov. uk/government/publications/sacn-carbohydrates-and-health-report (2015).
    • (2015) SACN Carbohydrates and Health Report
  • 179
    • 77955782296 scopus 로고    scopus 로고
    • Scientific opinion on dietary reference values for carbohydrates and dietary fibre
    • EFSA Panel on Dietetic Products, Nutrition, and Allergies
    • EFSA Panel on Dietetic Products, Nutrition, and Allergies. Scientific opinion on dietary reference values for carbohydrates and dietary fibre. EFSA Journal 8, 1462 (2010).
    • (2010) EFSA Journal , vol.8 , pp. 1462
  • 180
    • 0028476745 scopus 로고
    • The colon as a metabolic organ
    • O'Keefe, S. J. The colon as a metabolic organ. S. Afr. Med. J. 84, 376-377 (1994).
    • (1994) S. Afr. Med. J. , vol.84 , pp. 376-377
    • O'Keefe, S.J.1
  • 181
    • 0029038459 scopus 로고
    • Food and the gut
    • Walker Lecture
    • O'Keefe, S. J. A. R. P. Walker Lecture. Food and the gut. S. Afr. Med. J. 85, 261-268 (1995).
    • (1995) S. Afr. Med. J. , vol.85 , pp. 261-268
    • O'Keefe, S.J.A.R.P.1
  • 182
    • 0035184785 scopus 로고    scopus 로고
    • The African way of life and colon cancer risk
    • O'Keefe, S. J. The African way of life and colon cancer risk. Am. J. Gastroenterol. 96, 3220-3221 (2001).
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 3220-3221
    • O'Keefe, S.J.1
  • 183
    • 36549075219 scopus 로고    scopus 로고
    • Nutrition and colonic health: The critical role of the microbiota
    • O'Keefe, S. J. Nutrition and colonic health: the critical role of the microbiota. Curr. Opin. Gastroenterol. 24, 51-58 (2008).
    • (2008) Curr. Opin. Gastroenterol. , vol.24 , pp. 51-58
    • O'Keefe, S.J.1
  • 184
    • 0033135551 scopus 로고    scopus 로고
    • Rarity of colon cancer in Africans is associated with low animal product consumption, not fiber
    • O'Keefe, S. J., Kidd, M., Espitalier-Noel, G. & Owira, P. Rarity of colon cancer in Africans is associated with low animal product consumption, not fiber. Am. J. Gastroenterol. 94, 1373-1380 (1999).
    • (1999) Am. J. Gastroenterol. , vol.94 , pp. 1373-1380
    • O'Keefe, S.J.1    Kidd, M.2    Espitalier-Noel, G.3    Owira, P.4
  • 185
    • 70350310104 scopus 로고    scopus 로고
    • Products of the colonic microbiota mediate the effects of diet on colon cancer risk
    • O'Keefe, S. J. et al. Products of the colonic microbiota mediate the effects of diet on colon cancer risk. J. Nutr. 139, 2044-2048 (2009).
    • (2009) J. Nutr. , vol.139 , pp. 2044-2048
    • O'Keefe, S.J.1
  • 186
    • 84863709139 scopus 로고    scopus 로고
    • A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice
    • Park, H. et al. A high-fat diet increases angiogenesis, solid tumor growth, and lung metastasis of CT26 colon cancer cells in obesity-resistant BALB/c mice. Mol. Carcinog. 51, 869-880 (2012).
    • (2012) Mol. Carcinog. , vol.51 , pp. 869-880
    • Park, H.1
  • 187
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens, L. M. & Werb, Z. Inflammation and cancer. Nature 420, 860-867 (2002).
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2


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