Gut microbial metabolism drives transformation of msh2-deficient colon epithelial cells

Cell

Volumn 158, Issue 2, 2014, Pages 288-299

  Belcheva, Antoaneta ^a   Irrazabal, Thergiory ^a   Robertson, Susan J ^a   Streutker, Catherine ^b   Maughan, Heather ^c   Rubino, Stephen ^a   Moriyama, Eduardo H ^d   Copeland, Julia K ^e   Kumar, Sachin ^a   Green, Blerta ^a   Geddes, Kaoru ^a   Pezo, Rossanna C ^f   Navarre, William W ^a   Milosevic, Michael ^d   Wilson, Brian C ^d   Girardin, Stephen E ^a   Wolever, Thomas M S ^f   Edelmann, Winfried ^g   Guttman, David S ^e   Philpott, Dana J ^a   Martin, Alberto ^a   more..

^a UNIVERSITY OF TORONTO   (Canada)

^b ST MICHAEL'S HOSPITAL   (Canada)

^c RONIN INSTITUTE   (United States)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF TORONTO   (Canada)

^g ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; APC PROTEIN; BETA CATENIN; BUTYRIC ACID; METRONIDAZOLE; NEOMYCIN; PROTEIN MSH2; VANCOMYCIN; ADENOSINE TRIPHOSPHATASE; CARBOHYDRATE; RNA 16S; TRIBUTYRIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BACTERIAL LOAD; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TRANSFORMATION; COLON MUCOSA; COLORECTAL CANCER; CONTROLLED STUDY; DNA DAMAGE; EPITHELIUM CELL; GENE DELETION; GENE MUTATION; GENE SEQUENCE; GENOTYPE; HISTOPATHOLOGY; INTESTINE FLORA; LOW CARBOHYDRATE DIET; MICROBIAL COMMUNITY; MICROBIAL METABOLISM; MISMATCH REPAIR; MOUSE; NONHUMAN; PRIORITY JOURNAL; ABERRANT CRYPT FOCUS; ANTIBIOTIC THERAPY; APOPTOSIS; CELL CYCLE ARREST; COLON; COLON FLORA; COLON POLYP; COMET ASSAY; DIET; DNA STRAND BREAKAGE; GENETIC MANIPULATION; HOMOLOGOUS RECOMBINATION; INFLAMMATORY CELL; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; LYMPHOCYTE SUBPOPULATION; MUTATION RATE; NEUTROPHIL; PHENOTYPE; SMALL INTESTINE; TH1 CELL; TH17 CELL;

MUS;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOMATOUS POLYPOSIS COLI PROTEIN; ANIMALS; BETA CATENIN; BUTYRATES; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; COLONIC POLYPS; COLORECTAL NEOPLASMS; DIETARY CARBOHYDRATES; DNA MISMATCH REPAIR; EPITHELIAL CELLS; INFLAMMATION; MICE; MICE, INBRED C57BL; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 84904543667     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.04.051     Document Type: Article

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