Interaction of polyunsaturated fatty acids and sodium butyrate during apoptosis in HT-29 human colon adenocarcinoma cells

European Journal of Nutrition

Volumn 44, Issue 1, 2005, Pages 40-51

  Hofmanová, Jiřina ^a   Vaculová, Alena ^a   Lojek, Antonín ^a   Kozubík, Alois ^a  

^a INSTITUTE OF BIOPHYSICS   (Czech Republic)

Author keywords

Apoptosis; Butyrate; Colon cancer; Diet; Polyunsaturated fatty acids

Indexed keywords

ANTIOXIDANT; ARACHIDONIC ACID; BUTYRIC ACID; CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE INHIBITOR 1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLOHEXIMIDE; DOCOSAHEXAENOIC ACID; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; POLYUNSATURATED FATTY ACID; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN SYNTHESIS INHIBITOR; REACTIVE OXYGEN METABOLITE; TROLOX C;

AEROBIC METABOLISM; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL CYCLE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL POPULATION; CELL PROLIFERATION; CELL STRAIN; COLON ADENOCARCINOMA; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIPID PEROXIDATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; MOLECULE; PARAMETER; PROTEIN DEGRADATION; PROTEIN EXPRESSION;

ADENOCARCINOMA; APOPTOSIS; ARACHIDONIC ACID; BLOTTING, WESTERN; BUTYRATES; CASPASE 3; CASPASE 9; CASPASES; CELL CYCLE; COLONIC NEOPLASMS; DOCOSAHEXAENOIC ACIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FATTY ACIDS, UNSATURATED; FLOW CYTOMETRY; HT29 CELLS; HUMANS; LIPID PEROXIDATION; MEMBRANE POTENTIALS; MICROSCOPY, FLUORESCENCE; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES;

EID: 13844266089     PISSN: 14366207     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00394-004-0490-2     Document Type: Article

References (49)

1. Chapkin RS, Fan Y, Lupton JR (2000) Effect of diet on colonic-programmed cell death: molecular mechanism of action. Toxicol Lett 113:411-414
2. Bedi B, Pasricha PJ, Akhtar AJ, et al. (1995) Inhibition of apoptosis during development of colorectal cancer. Cancer Res 55:1811-1816
3. Hague A, Singh B, Paraskeva C (1997) Butyrate acts as a survival factor for colonic epithelial cells: further fuel for the in vivo versus in vitro debate. Gastroenterology 112:1036-1040
4. Smith JG, Yokoyama WH, German JB (1998) Butyric acid from the diet: actions at the level of gene expression. Crit Rev Food Sci Nutr 38:259-297
5. Iacomino G, Tecce MF, Grimaldi C, Tosto M, Russo GL (2001) Transcriptional response of a human colon adenocarcinoma cell line to sodium butyrate. Biochem Biophys Res Commun 285:1280-1289
6. Tan S, Seow TK, Liang RCMY, et al. (2002) Proteome analysis of butyrate-treated human colon cancer cells (HT-29). Int J Cancer 98:523-531
7. Giardina C, Boulares H, Inan MS (1999) NSAIDs and butyrate sensitize a human colorectal cancer cell line to TNF-alpha and Fas ligation: the role of reactive oxygen species. Biochim Biophys Acta 1448:425-438
8. Kovaříková M, Pacherník J, Hofmanová J, Zadák Z, Kozubík A (2000) TNF-alpha modulates the differentiation induced by butyrate in the HT-29 human colon adenocarcinoma cell line. Eur J Cancer 36:1844-1852
9. Bonnotte B, Favre N, Reveneau S, et al. (1998) Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate. Cell Death Differ 5:480-487
10. Bartsch H, Nair J, Owen RW (1999) Dietary polyunsaturated fatty acids and cancers of the breast and colorectum: emerging evidence for their role as risk modifiers. Carcinogenesis 20: 2209-2218
11. Diggle CP (2002) In vitro studies on the relationship between polyunsaturated fatty acids and cancer: tumour or tissue specific effects? Prog Lipid Res 41: 240-253
12. Petrik MB, McEntee MF, Johnson BT, Obukowicz MG, Whelan J (2000) Highly unsaturated (n-3) fatty acids, but not alpha-linolenic, conjugated linoleic or gamma-linolenic acids, reduce tumorigenesis in Apc(Min/+) mice. J Nutr 130: 2434-2443
13. Di Marzo V (1995) Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions. Prostaglandins Leukot Essent Fatty Acids 53:239-254
14. Calder PC (2001) Polyunsaturated fatty acids, inflammation, and immunity. Lipids 36:1007-1024
15. Rudolph IL, Kelley DS, Klasing KC, Erickson KL (2001) Regulation of cellular differentiation and apoptosis by fatty acids and their metabolites. Nutr Res 21:381-393
16. Spector AA, Burns CP (1987) Biological and therapeutic potential of membrane lipid modification in tumors. Cancer Res 47:4529-4537
17. Bégin ME, Ells G, Horrobin DF (1988) Polyunsaturated fatty acid-induced cytotoxicity against tumor cells and its relationship to lipid peroxidation. J National Cancer Inst 80:188-194
18. Neoptolemos JP, Husband D, Imray C, Rowley S, Lawson N (1991) Arachidonic acid and docosahexaenoic acid are increased in human colorectal cancer. Gut 32:278-281
19. Liebich HM, Wirth C, Jakober B (1991) Analysis of polyunsaturated fatty acids in blood serum after fish oil administration. J Chromatogr 572:1-9
20. Canute RA, Muzio G, Bassi AM, et al. (1995) Enrichment with arachidonic acid increases the sensitivity of hepatoma cells to the cytotoxic effects of oxidative stress. Free Radic Biol Med 18:287-293
21. Vaculová A, Hofmanová J, Souček K, Kovaříková M, Kozubík A (2002) Tumor necrosis factor-alpha induces apoptosis associated with poly(ADP-ribose) polymerase cleavage in HT-29 colon cancer cells. Anticancer Res 22:1635-1639
22. Aw TY (1999) Molecular and cellular responses to oxidative stress and changes in oxidation-reduction imbalance in the intestine. Am J Clin Nutr 70:557-565
23. Grammatikos SI, Subbaiah PV, Victor TA, Miller WM (1994) Diverse effects of essential (n-6 and n-3) fatty acids on cultured cells. Cytotechnology 15:31-50
24. Anti M, Armelao F, Marra G, et al. (1994) Effects of different doses of fish oil on rectal cell proliferation in patients with sporadic colonic adenomas. Gastroenterology 107:1709-1718
25. Chang WL, Chapkin RS, Lupton JR (1998) Fish oil blocks azoxymethane-induced rat colon tumorigenesis by increasing cell differentiation and apoptosis rather than decreasing cell proliferation. J Nutr 128:491-497
26. Das UN (1991) Tumoricidal action of cis-unsaturated fatty acids and their relationship to free radicals and lipid peroxidation. Cancer Lett 56:235-243
27. Chapkin RS, Hong MY, Fan YY, et al. (2002) Dietary n-3 PUFA alter colonocyte mitochondrial membrane composition and function. Lipids 37:193-199
28. Krause W, DuBois RN (2000) Eicosanoids and the large intestine. Prostaglandins Other Lipid Mediat 61: 145-161
29. Watkins SM, Carter LC, German JB (1998) Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production. J Lipid Res 39: 1583-1588
30. Coradini D, Pellizzaro C, Marimpietri D, Abolafio G, Daidone MG (2000) Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells. Cell Prolif 33: 139-146
31. Heerdt BG, Houston MA, Augenlicht LH (1994) Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res 54:3288-3293
32. Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D, Paraskeva C (1993) Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. Int J Cancer 55:498-505
33. Wang J, Friedman EA (1998) Short-chain fatty acids induce cell cycle inhibitors in colonocytes. Gastroenterology 114:940-946
34. Narayanan BA, Narayanan NK, Reddy BS (2001) Docosahexaenoic acid regulated genes and transcription factors inducing apoptosis in human colon cancer cells. Int J Oncol 19:1255-1262
35. Wachtershauser A, Stein J (2001) Butyrate-induced differentiation of Caco-2 cells occurs independently from p27. Biochem Biophys Res Commun 281: 295-299
36. Quaroni A, Tian JQ, Seth P, Rhys CA (2000) p27(Kip1) is an inducer of intestinal epithelial cell differentiation. Am J Physiol Cell Physiol 279: C1045-C1057
37. van de Water B, Nagelkerke JF, Stevens JL (1999) Dephosphorylation of focal adhesion kinase (FAK) and loss of focal contacts precede caspase-mediated cleavage of FAK during apoptosis in renal epithelial cells. J Biol Chem 274: 13328-13337
38. Heerdt BG, Houston MA, Anthony GM, Augenlicht LH (1998) Mitochondrial membrane potential (delta psi(mt)) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells. Cancer Res 58:2869-2875
39. Ruemmele FM, Dionne S, Qureshi I, Sarma DS, Levy E, Seidman EG (1999) Butyrate mediates Caco-2 cell apoptosis via up-regulation of pro-apoptotic BAK and inducing caspase-3 mediated cleavage of poly-(ADP-ribose) polymerase (PARP). Cell Death Differ 6: 729-735
40. Mancini M, Nicholson DW, Roy S, et al. (1998) The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signaling. J Cell Biol 140:1485-1495
41. Horvath PJ, Awad AB, Andersen M (1993) Differential effect of butyrate on lipids of human colon cancer cells. Nutr Cancer 20:283-291
42. Tang DG, La E, Kern J, Kehrer JP (2002) Fatty acid oxidation and signaling in apoptosis. Biol Chem 383:425-442
43. Hong MY, Chapkin RS, Barhoumi R, et al. (2002) Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. Carcinogenesis 23:1919-1925
44. Scorrano L, Penzo D, Petronilli V, Pagano F, Bernardi P (2001) Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha apoptotic signaling. J Biol Chem 276:12035-12040
45. Pompeia C, Lima T, Curi R (2003) Arachidonic acid cytotoxicity: can arachidonic acid be a physiological mediator of cell death? Cell Biochem Funct 21:97-104
46. Narayanan BA, Narayanan NK, Simi B, Reddy BS (2003) Modulation of inducible nitric oxide synthase and related proinflammatory genes by the omega-3 fatty acid docosahexaenoic acid in human colon cancer cells. Cancer Res 63:972-979
47. Fan YY, Spencer TE, Wang N, Moyer MP, Chapkin RS (2003) Chemopreventive n-3 fatty acids activate RXRalpha in colonocytes. Carcinogenesis 24: 1541-1548
48. Merchant AK, Loney TL, Maybaum J (1996) Expression of wild-type p53 stimulates an increase in both Bax and Bcl-xL protein content in HT29 cells. Oncogene 13:2631-2637
49. Yang T, Buchan HL, Townsend KJ, Craig RW (1996) MCL-1, a member of the BLC-2 family, is induced rapidly in response to signals for cell differentiation or death, but not to signals for cell proliferation. J Cell Physiol 166:523-536