Dietary manipulation of oncogenic microRNA expression in human rectal mucosa: A randomized trial

Cancer Prevention Research

Volumn 7, Issue 8, 2014, Pages 786-795

  Humphreys, Karen J ^a   Conlon, Michael A ^b   Young, Graeme P ^a   Topping, David L ^b   Hu, Ying ^a   Winter, Jean M ^a   Bird, Anthony R ^b   Cobiac, Lynne ^b   Kennedy, Nicholas A ^c   Michael, Michael Z ^a   Le Leu, Richard K ^b  

^a FLINDERS UNIVERSITY   (Australia)

^b CSIRO   (Australia)

^c FLINDERS MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOSE; BUTYRIC ACID; CYCLIN DEPENDENT KINASE INHIBITOR 1A; MICRORNA; MICRORNA 17; MICRORNA 19A; MICRORNA 19B; MICRORNA 20A; MICRORNA 21; STARCH; UNCLASSIFIED DRUG; MIRN17-92 MICRORNA, HUMAN;

ADULT; AGED; ARTICLE; CANCER RISK; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; CROSSOVER PROCEDURE; DIET SUPPLEMENTATION; DIETARY INTAKE; FECES ANALYSIS; FEMALE; GENE CLUSTER; GENE EXPRESSION; GENE TARGETING; GENETIC MANIPULATION; HIGH RED MEAT; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IN VIVO STUDY; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECTUM MUCOSA; RED MEAT; ANIMAL; BEVERAGE; BIOPSY; CHEMISTRY; CITRUS; CLUSTER ANALYSIS; DIET; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTESTINE; INTESTINE MUCOSA; MAIZE; MEAT; METABOLISM; MICROBIOLOGY; MIDDLE AGED; MILK; MULTIGENE FAMILY; RECTUM TUMOR;

AGED; AMYLOSE; ANIMALS; BEVERAGES; BIOPSY; CELL PROLIFERATION; CITRUS; CLUSTER ANALYSIS; CROSS-OVER STUDIES; DIET; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTESTINAL MUCOSA; INTESTINES; MALE; MEAT; MICRORNAS; MIDDLE AGED; MILK; MULTIGENE FAMILY; RECTAL NEOPLASMS; STARCH; ZEA MAYS;

EID: 84905859180     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-14-0053     Document Type: Article

References (50)

1. WCRF. Food, Nutrition, Physical Activity and the Prevention of Cancer: a Global Perspective. Washington DC: World Cancer Research Fund/American Institute for Cancer Research; 2007.
2. Chan DSM, Lau R, Aune D, Vieira R, Greenwood DC, Kampman E, et al. Red and processed meat and colorectal cancer incidence: metaanalysis of prospective studies. PLoS ONE 2011;6:e20456.
3. Toden S, Bird AR, Topping DL, Conlon MA. Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats. Cancer Biol Ther 2006;5:267-72.
4. Lewin MH, Bailey N, Bandaletova T, Bowman R, Cross AJ, Pollock J, et al. Red meat enhances the colonic formation of the DNA adduct O6-carboxymethyl guanine: implications for colorectal cancer risk. Cancer Res 2006;66:1859-65. (Pubitemid 43259973)
5. Le Leu RK, Young GP, Hu Y, Winter J, Conlon MA. Dietary red meat aggravates dextran sulfate sodium-induced colitis in mice whereas resistant starch attenuates inflammation. Dig Dis Sci 2013;58:3475-82.
6. David LA, Maurice CF, Carmody RN, Gootenberg DB, Button JE, Wolfe BE, et al. Diet rapidly and reproducibly alters the human gut microbiome. Nature 2014;505:559-63.
7. Asano T, McLeod RS. Dietary fibre for the prevention of colorectal adenomas and carcinomas. Cochrane Database Syst Rev 2002:CD003430.
8. Medina V, Edmonds B, Young GP, James R, Appleton S, Zalewski PD. Induction of caspase-3 protease activity and apoptosis by butyrate and trichostatin A (inhibitors of histone deacetylase): dependence on protein synthesis and synergy with a mitochondrial/cytochrome c-dependent pathway. Cancer Res 1997;57:3697-707. (Pubitemid 27381212)
9. Mariadason JM, Corner GA, Augenlicht LH. Genetic reprogramming in pathways of colonic cell maturation induced by short chain fatty acids: comparison with trichostatin A, sulindac, and curcumin and implications for chemoprevention of colon cancer. Cancer Res 2000;60:4561-72. (Pubitemid 32103641)
10. Medina V, Afonso JJ, Alvarez-Arguelles H, Hernandez C, Gonzalez F. Sodium butyrate inhibits carcinoma development in a 1,2-dimethyl-hydrazine-induced rat colon cancer. JPEN J Parenter Enteral Nutr 1998;22:14-7.
11. Le Leu RK, Brown IL, Hu Y, Esterman A, Young GP. Suppression of azoxymethane-induced colon cancer development in rats by dietary resistant starch. Cancer Biol Ther 2007;6:1621-6. (Pubitemid 351590335)
12. Daly K, Shirazi-Beechey SP. Microarray analysis of butyrate regulated genes in colonic epithelial cells. DNA Cell Biol 2006;25:49-62. (Pubitemid 43089752)
13. Toyota M, Ahuja N, Ohe-Toyota M, Herman JG, Baylin SB, Issa JP. CpG island methylator phenotype in colorectal cancer. Proc Natl Acad Sci U S A 1999;96:8681-6. (Pubitemid 29354851)
14. Enroth S, Rada-Iglesisas A, Andersson R, Wallerman O, Wanders A, Pahlman L, et al. Cancer associated epigenetic transitions identified by genome-wide histone methylation binding profiles in human colorectal cancer samples and paired normal mucosa. BMC Cancer 2011;11:450.
15. Michael MZ, O' Connor SM, van Holst Pellekaan NG, Young GP, James RJ. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol Cancer Res 2003;1:882-91. (Pubitemid 37288707)
16. Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr., Sjoblom T, et al. The colorectal microRNAome. Proc Natl Acad Sci U S A 2006;103:3687-92. (Pubitemid 43376616)
17. Chen X, Guo X, Zhang H, Xiang Y, Chen J, Yin Y, et al. Role of miR-143 targeting KRAS in colorectal tumorigenesis. Oncogene 2009;28:1385-92.
18. Humphreys KJ, Cobiac L, Le Leu RK, Van der Hoek MB, Michael MZ. Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Mol Carcinog 2013;52:459-74.
19. Phillips J, Muir JG, Birkett A, Lu ZX, Jones GP, O'Dea K, et al. Effect of resistant starch on fecal bulk and fermentation-dependent events in humans. Am J Clin Nutr 1995;62:121-30.
20. Bajka BH, Topping DL, Cobiac L, Clarke JM. Butyrylated starch is less susceptible to enzymic hydrolysis and increases large-bowel butyrate more than high-amylose maize starch in the rat. Br J Nutr 2006;96:276-82. (Pubitemid 46470095)
21. Clarke JM, Topping DL, Christophersen CT, Bird AR, Lange K, Saunders I, et al. Butyrate esterified to starch is released in the human gastrointestinal tract. Am J Clin Nutr 2011;94:1276-83.
22. Winter J, Nyskohus L, Young GP, Hu Y, Conlon MA, Bird AR, et al. Inhibition by resistant starch of red meat-induced promutagenic adducts in mouse colon. Cancer Prev Res 2011;4:1920-8.
23. Bajka BH, Clarke JM, Cobiac L, Topping DL. Butyrylated starch protects colonocyte DNA against dietary protein-induced damage in rats. Carcinogenesis 2008;29:2169-74.
24. Annison G, Illman RJ, Topping DL. Acetylated, propionylated or butyrylated starches raise large bowel short-chain fatty acids preferentially when fed to rats. J Nutr 2003;133:3523-8. (Pubitemid 37409482)
25. Muller PY, Janovjak H, Miserez AR, Dobbie Z. Processing of gene expression data generated by quantitative real-time RT-PCR. Biotechniques 2002;32:1372-4, 6, 8-9.
26. Chang KH, Mestdagh P, Vandesompele J, Kerin MJ, Miller N. MicroRNA expression profiling to identify and validate reference genes for relative quantification in colorectal cancer. BMC Cancer 2010;10:173.
27. Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell 2008;132:875-86. (Pubitemid 351312807)
28. Inomata M, Tagawa H, Guo YM, Kameoka Y, Takahashi N, Sawada K. MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes. Blood 2009;113:396-402.
29. Mu P, Han YC, Betel D, Yao E, Squatrito M, Ogrodowski P, et al. Genetic dissection of the miR-17-92 cluster of microRNAs in Myc-induced B-cell lymphomas. Genes Dev 2009;23:2806-11.
30. Olive V, Bennett MJ, Walker JC, Ma C, Jiang I, Cordon-Cardo C, et al. miR-19 is a key oncogenic component of miR17-92. Genes Dev 2009;23:2839-49.
31. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, et al. A microRNA polycistron as a potential human oncogene. Nature 2005;435:828-33. (Pubitemid 40839734)
32. Kahlert C, Klupp F, Brand K, Lasitschka F, Diederichs S, Kirchberg J, et al. Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases. Cancer Sci 2011;102:1799-807.
33. Yu G, Tang JQ, Tian ML, Li H, Wang X, Wu T, et al. Prognostic values of the miR-17-92 cluster and its paralogs in colon cancer. J Surg Oncol 2012;106:232-7.
34. Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 2007;133:647-58. (Pubitemid 47187346)
35. Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, et al. MicroRNA-21 (miR-21) post-transcriptionally down-regulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008;27:2128-36. (Pubitemid 351485639)
36. Medina PP, Nolde M, Slack FJ. OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma. Nature 2010;467:86-90.
37. Schetter AJ, Leung SY, Sohn JJ, Zanetti KA, Bowman ED, Yanaihara N, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299:425-36. (Pubitemid 351185951)
38. Le Leu RK, Hu Y, Brown IL, Young GP. Effect of high amylose maize starches on colonic fermentation and apoptotic response to DNA-damage in the colon of rats. Nutr Metab 2009;6:11.
39. Hendrickson DG, Hogan DJ, McCullough HL, Myers JW, Herschlag D, Ferrell JE, et al. Concordant regulation of translation and mRNA abundance for hundreds of targets of a human microRNA. PLoS Biol 2009;7:e1000238.
40. Ijssennagger N, Rijnierse A, de Wit N, Jonker-Termont D, Dekker J, Muller M, et al. Dietary haem stimulates epithelial cell turnover by downregulating feedback inhibitors of proliferation in murine colon. Gut 2012;61:1041-9.
41. Faller M, Matsunaga M, Yin S, Loo JA, Guo F. Heme is involved in microRNA processing. Nat Struct Mol Biol 2007;14:23-9. (Pubitemid 46067419)
42. Park JH, Ahn J, Kim S, Kwon DY, Ha TY. Murine hepatic miRNAs expression and regulation of gene expression in diet-induced obese mice. Mol Cells 2011;31:33-8.
43. Clarke JM, Young GP, Topping DL, Bird AR, Cobiac L, Scherer BL, et al. Butyrate delivered by butyrylated starch increases distal colonic epithelial apoptosis in carcinogen-treated rats. Carcinogenesis 2012;33:197-202.
44. Gibson PR, Moeller I, Kagelari O, Folino M, Young GP. Contrasting effects of butyrate on the expression of phenotypic markers of differentiation in neoplastic and non-neoplastic colonic epithelial cells in vitro. J Gastroenterol Hepatol 1992;7:165-72.
45. Warburg O. On the origin of cancer cells. Science 1956;123:309-14.
46. Davidson LA, Wang N, Shah MS, Lupton JR, Ivanov I, Chapkin RS. n-3 polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon. Carcinogenesis 2009;30:2077-84.
47. Shah MS, Schwartz SL, Zhao C, Davidson LA, Zhou B, Lupton JR, et al. Integrated microRNA and mRNA expression profiling in a rat colon carcinogenesis model: effect of a chemo-protective diet. Physiol Genomics 2011;43:640-54.
48. Daniel CR, Cross AJ, Koebnick C, Sinha R. Trends in meat consumption in the USA. Public Health Nutr 2011;14:575-83.
49. Burn J, Bishop DT, Chapman PD, Elliott F, Bertario L, Dunlop MG, et al. A randomized placebo-controlled prevention trial of aspirin and/or resistant starch in young people with familial adenomatous polyposis. Cancer Prev Res 2011;4:655-65.
50. Bird AR, Vuaran MS, King RA, Noakes M, Keogh J, Morell MK, et al. Wholegrain foods made from a novel high-amylose barley variety (Himalaya 292) improve indices of bowel health in human subjects. Br J Nutr 2008;99:1032-40.