Changes seen in gut bacteria content and distribution with obesity: Causation or association?

Postgraduate Medicine

Volumn 127, Issue 8, 2015, Pages 863-868

  Bell, David S H ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

Diet; Fecal transplant; Gastric bypass; Gut microbiota; Obesity

Indexed keywords

FARNESOID X RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; HIGH DENSITY LIPOPROTEIN; PREBIOTIC AGENT; PROBIOTIC AGENT; SWEETENING AGENT; BILE ACID; CELL RECEPTOR; FARNESOID X-ACTIVATED RECEPTOR;

BACTERIAL TRANSMISSION; BACTEROIDETES; CALORIC RESTRICTION; CIRCADIAN RHYTHM; DIET; DIET INDUCED OBESITY; DIETARY FIBER; DISEASE ASSOCIATION; DYSBIOSIS; EXERCISE; FECAL MICROBIOTA TRANSPLANTATION; FEEDING BEHAVIOR; FIRMICUTES; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; HUMAN; HYPERGLYCEMIA; INSULIN SENSITIVITY; INTESTINE FLORA; LACTOBACILLUS; LIPID DIET; LIPID STORAGE; METABOLIC SYNDROME X; NONHUMAN; OBESITY; REVIEW; WEIGHT GAIN; WEIGHT REDUCTION; WESTERN DIET; ANIMAL; GASTRIC BYPASS SURGERY; GASTROINTESTINAL TRACT; GROWTH, DEVELOPMENT AND AGING; INFLAMMATION; METABOLISM; MICROBIOLOGY; MICROFLORA; PHYSIOLOGY;

ANIMALS; BACTEROIDETES; BILE ACIDS AND SALTS; DIET, WESTERN; FIRMICUTES; GASTRIC BYPASS; GASTROINTESTINAL TRACT; HUMANS; INFLAMMATION; MICROBIOTA; OBESITY; RECEPTORS, CYTOPLASMIC AND NUCLEAR; WEIGHT LOSS;

EID: 84964000638     PISSN: 00325481     EISSN: 19419260     Source Type: Journal    
DOI: 10.1080/00325481.2015.1098519     Document Type: Review

References (58)

1. Hooper LV, Gordon JI. Commensal host-bacterial relationships in the gut. Science. 2001;292(5519):1115–1118.
2. Qin J, Li R, Raes J, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 2010;464 (7285):59–65.
3. Neish AS. Microbes in gastrointestinal health and disease. Gastroenterology. 2009;136(1):65–80.
4. Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308(5728):1635–1638.
5. Lee YK, Mazmanian SK. Has the microbiota played a critical role in the evolution of the adaptive immune system? Science. 2010;330 (6012):1768–1773.
6. Murphy EF, Cotter PD, Healy S, et al. Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models. Gut. 2010;59(12):1635–1642.
7. Mueller NT, Whyatt R, Hoepner L, et al. Prenatal exposure to antibiotics, cesarean section and risk of childhood obesity. Int J Obes (Lond). 2014. [Epub ahead of print]. DOI:10.1038/ijo.2014.180.
8. Lee SA, Lim JY, Kim BS, et al. Comparison of the gut microbiota profile in breast-fed and formula-fed Korean infants using pyrosequencing. Nutr Res Pract. 2015;9(3):242–248.
9. Zapata HJ, Quagliarello VJ. The microbiota and microbiome in aging: potential implications in health and age-related diseases. J Am Geriatr Soc. 2015;63(4):776–781.
10. Vangay P, Ward T, Gerber JS, et al. Antibiotics, pediatric dysbiosis, and disease. Cell Host Microbe. 2015;17(5):553–564.
11. Membrez M, Blancher F, Jaquet M, et al. Gut microbiota modulation with norfloxacin and ampicillin enhances glucose tolerance in mice. FASEB J. 2008;22(7):2416–2426.
12. De Angelis M, Francavilla R, Piccolo M, et al. Autism spectrum disorders and intestinal microbiota. Gut Microbes. 2015;6 (3):207–213.
13. McLean MH, Dieguez D Jr, Miller LM, et al. Does the microbiota play a role in the pathogenesis of autoimmune diseases? Gut. 2015;64(2):332–341.
14. Salazar N, Arboleya S, Valdes I, et al. The human intestinal microbiome at an extreme ages of life. Dietary intervention as a way to counteract alterations. Front Genet. 2014;5:406. DOI:10.3389/gene.2014.00406.
15. Clarke SF, Murphy EF, O’Sullivan O, et al. Exercise and associated dietary extremes impact on gut microbial diversity. Gut. 2014;63 (12):1913–1920.
16. Flint HJ. Obesity and the gut microbiota. J Clin Gastroenterol. 2011;45(Suppl):S128–32.
17. Krznarić Z, Vranešić Bender D, Kunović A, et al. Gut microbiota and obesity. Dig Dis. 2012;30(2):196–200.
18. Graf D, Di Cagno R, Fåk F, et al. Contribution of diet to the composition of the human gut microbiota. Microb Ecol Health Dis. 2015;26:26164.
19. Hold GL. Western lifestyle: a ‘master’ manipulator of the intestinal microbiota? Gut. 2014;63(1):5–6.
20. Schnorr SL, Candela M, Rampelli S, et al. Gut microbiome of the Hadza hunter-gatherers. Nat Commun. 2014;5:3654.
21. Suez J, Korem T, Zeevi D, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014;514(7521):181–186.
22. Voigt RM, Forsyth CB, Green SJ, et al. Circadian disorganization alters intestinal microbiota. PLoS One. 2014;9(5):e97500.
23. Han JL, Lin HL. Intestinal microbiota and type 2 diabetes: from mechanism insights to therapeutic perspective. World J Gastroenterol. 2014;20(47):17737–17745.
24. Lindsay KL, Kennelly M, Culliton M, et al. Probiotics in obese pregnancy do not reduce maternal fasting glucose: a double-blind, placebo-controlled, randomized trial (Probiotics in Pregnancy Study). Am J Clin Nutr. 2014;99(6):1432–1439.
25. Karlsson Videhult F, Öhlund I, Stenlund H, et al. Probiotics during weaning: a follow-up study on effects on body composition and metabolic markers at school age. Eur J Nutr. 2015;54 (3):355–363.
26. Moroti C, Souza Magri LF, de Rezende Costa M, et al. Effect of the consumption of a new symbiotic shake on glycemia and cholesterol levels in elderly people with type 2 diabetes mellitus. Lipids Health Dis. 2012;11:29.
27. Yadav H, Jain S, Sinha PR. Antidiabetic effect of probiotic dahi containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. Nutrition. 2007;23(1):62–68.
28. Chou CJ, Membrez M, Blancher F. Gut decontamination with norfloxacin and ampicillin enhances insulin sensitivity in mice. Nestle Nutr Workshop Ser Pediatr Program. 2008;62:127–137; discussion 137-40.
29. Thuny F, Richet H, Casalta JP, et al. Vancomycin treatment of infective endocarditis is linked with recently acquired obesity. PLoS One. 2010;5(2):e9074.
30. van Nood E, Vrieze A, Nieuwdorp M, et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med. 2013;368(5):407–415.
31. Vrieze A, Van Nood E, Holleman F, et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology. 2012;143 (4):913–6.e7.
32. Ley RE, Turnbaugh PJ, Klein S, et al. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444 (7122):1022–1023.
33. DiBaise JK, Zhang H, Crowell MD, et al. Gut microbiota and its possible relationship with obesity. Mayo Clin Proc. 2008;83 (4):460–469.
34. Tilg H, Moschen AR. Microbiota and diabetes: an evolving relationship. Gut. 2014;63(9):1513–1521.
35. Arslan N. Obesity, fatty liver disease and intestinal microbiota. World J Gastroenterol. 2014;20(44):16452–16463.
36. Festi D, Schiumerini R, Eusebi LH, et al. Gut microbiota and metabolic syndrome. World J Gastroenterol. 2014;20(43):16079–16094.
37. Lefebvre P, Cariou B, Lien F, et al. Role of bile acids and bile acid receptors in metabolic regulation. Physiol Rev. 2009;89 (1):147–191.
38. Prabha V, Ohri M. Review: bacterial transformations of bile acids. World J Microbiol Biotechnol. 2006;22:191–196.
39. Sayin SI, Wahlström A, Felin J, et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab. 2013;17 (2):225–235.
40. Kurdi P, Kawanishi K, Mizutani K, et al. Mechanism of growth inhibition by free bile acids in lactobacilli and bifidobacteria. J Bacteriol. 2006;188(5):1979–1986.
41. Islam KB, Fukiya S, Hagio M, et al. Bile acid is a host factor that regulates the composition of the cecal microbiota in rats. Gastroenterology. 2011;141(5):1773–1781.
42. Hylemon PB, Zhou H, Pandak WM, et al. Bile acids as regulatory molecules. J Lipid Res. 2009;50(8):1509–1520.
43. Prawitt J, Abdelkarim M, Stroeve JH, et al. Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity. Diabetes. 2011;60(7):1861–1871.
44. Ryan KK, Tremaroli V, Clemmensen C, et al. FXR is a molecular target for the effects of vertical sleeve gastrectomy. Nature. 2014;509(7499):183–188.
45. Horton F, Wright J, Smith L, et al. Increased intestinal permeability to oral chromium (51 Cr) -EDTA in human type 2 diabetes. Diabet Med. 2014;31(5):559–563.
46. Cani PD, Possemiers S, Van de Wiele T, et al. Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability. Gut. 2009;58(8):1091–1103.
47. Everard A, Lazarevic V, Derrien M, et al. Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice. Diabetes. 2011;60 (11):2775–2786.
48. Cani PD, Everard A. Akkermansia muciniphila: a novel target controlling obesity, type 2 diabetes and inflammation? Med Sci (Paris). 2014;302:125–127. Article in French.
49. Hansotia T, Maida A, Flock G, et al. Extrapancreatic incretin receptors modulate glucose homeostasis, body weight, and energy expenditure. J Clin Invest. 2007;117(1):143–152.
50. Dubé PE, Brubaker PL. Frontiers in glucagon-like peptide-2: multiple actions, multiple mediators. Am J Physiol Endocrinol Metab. 2007;293(2):E460–5.
51. Yadav H, Lee JH, Lloyd J, et al. Beneficial metabolic effects of a probiotic via butyrate-induced GLP-1 hormone secretion. J Biol Chem. 2013;288(35):25088–25097.
52. Zhou J, Martin RJ, Tulley RT, et al. Dietary resistant starch upregulates total GLP-1 and PYY in a sustained day-long manner through fermentation in rodents. Am J Physiol Endocrinol Metab. 2008;295(5):E1160–6.
53. van Dongen J, Willemsen G, Heijmans BT, et al. Longitudinal weight differences, gene expression, and blood biomarkers in BMI discordant identical twins. Int J Obes (Lond). 2015;39 (6):899–909.
54. Bäckhed F, Manchester JK, Semenkovich CF, et al. Mechanisms underlying the resistance to diet-induced obesity in germ-freemice. ProcNatl Acad Sci USA. 2007;104(3):979–984.
55. Bäckhed F, Ding H, Wang T, et al. The gut microbiota as an environmental factor that regulates fat storage. Proc Natl Acad Sci USA. 2004;101(44):15718–15723.
56. Osto M, Abegg K, Bueter M, et al. Roux-en-Y gastric bypass surgery in rats alters gut microbiota profile along the intestine. Physiol Behav. 2013;119:92–96.
57. Ridaura VK, Faith JJ, Rey FE, et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science. 2013;341(6150):1241214.
58. Chambers AP, Jessen L, Ryan KK, et al. Weight-independent changes in blood glucose homeostasis after gastric bypass or vertical sleeve gastrectomy in rats. Gastroenterology. 2011;141 (3):950–958.