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Volumn 92, Issue , 2016, Pages 8-16

In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: A new potentiality for ellagitannin metabolites against cancer

Author keywords

Chemoprevention; Colon cancer; Ellagic acid; Metabotype; Stem cells; Urolithins

Indexed keywords

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC AGENT; DRUG METABOLITE; ELLAGIC ACID; ELLAGITANNIN; ISOUROLITHIN A; UNCLASSIFIED DRUG; UROLITHIN A; UROLITHIN B; UROLITHIN C; UROLITHIN DARIVATIVE; 3,8-DIHYDROXY-6H-DIBENZO(B,D)PYRAN-6-ONE; COUMARIN DERIVATIVE; TANNIN; TUMOR MARKER;

EID: 84962281072     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2016.03.011     Document Type: Article
Times cited : (60)

References (60)
  • 2
    • 84896068181 scopus 로고    scopus 로고
    • The culture of cancer cell lines as tumorspheres does not systematically result in cancer stem cell enrichment
    • Calvet C.Y., André F.M., Mir L.M. The culture of cancer cell lines as tumorspheres does not systematically result in cancer stem cell enrichment. PLoS One 2014, 9:e89644.
    • (2014) PLoS One , vol.9 , pp. e89644
    • Calvet, C.Y.1    André, F.M.2    Mir, L.M.3
  • 3
    • 84929486032 scopus 로고    scopus 로고
    • Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells
    • Cho H., Jung H., Lee H., Yi H.C., Kwak H., Hwang K.T. Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells. Food Funct. 2015, 6:1675-1683.
    • (2015) Food Funct. , vol.6 , pp. 1675-1683
    • Cho, H.1    Jung, H.2    Lee, H.3    Yi, H.C.4    Kwak, H.5    Hwang, K.T.6
  • 4
    • 0034657277 scopus 로고    scopus 로고
    • Ellagitannins- nature, occurrence and dietary burden
    • Clifford M.N., Scalbert A. Ellagitannins- nature, occurrence and dietary burden. J. Sci. Food Agric. 2000, 80:1118-1125.
    • (2000) J. Sci. Food Agric. , vol.80 , pp. 1118-1125
    • Clifford, M.N.1    Scalbert, A.2
  • 6
    • 77953663505 scopus 로고    scopus 로고
    • Antibodies targeting cancer stem cells. A new paradigm in immunotherapy
    • Deonarain M.P., Kousparou C.S., Epenetos A.A. Antibodies targeting cancer stem cells. A new paradigm in immunotherapy. Mabs 2009, 1:12-26.
    • (2009) Mabs , vol.1 , pp. 12-26
    • Deonarain, M.P.1    Kousparou, C.S.2    Epenetos, A.A.3
  • 10
    • 84904903972 scopus 로고    scopus 로고
    • Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway
    • Fu Y., Chang H., Peng X., Bai Q., Yi L., Zhou Y., Zhu J., Mi M. Resveratrol inhibits breast cancer stem-like cells and induces autophagy via suppressing Wnt/β-catenin signaling pathway. PLoS One 2014, 9. e102535.
    • (2014) PLoS One , vol.9
    • Fu, Y.1    Chang, H.2    Peng, X.3    Bai, Q.4    Yi, L.5    Zhou, Y.6    Zhu, J.7    Mi, M.8
  • 12
    • 84959858829 scopus 로고    scopus 로고
    • Chromatographic and spectroscopic characterization of urolithins for their determination in biological samples after the intake of foods containing ellagitannins and ellagic acid
    • García-Villalba R., Espín J.C., Tomás-Barberán F.A. Chromatographic and spectroscopic characterization of urolithins for their determination in biological samples after the intake of foods containing ellagitannins and ellagic acid. J. Chromatogr. A 2016, 1428:162-175.
    • (2016) J. Chromatogr. A , vol.1428 , pp. 162-175
    • García-Villalba, R.1    Espín, J.C.2    Tomás-Barberán, F.A.3
  • 17
    • 77956196994 scopus 로고    scopus 로고
    • NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts
    • González-Sarrías A., Larrosa M., Tomás-Barberán F.A., Dolara P., Espín J.C. NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts. Br. J. Nutr. 2010, 104:503-512.
    • (2010) Br. J. Nutr. , vol.104 , pp. 503-512
    • González-Sarrías, A.1    Larrosa, M.2    Tomás-Barberán, F.A.3    Dolara, P.4    Espín, J.C.5
  • 18
    • 84877295491 scopus 로고    scopus 로고
    • The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP)
    • González-Sarrías A., Miguel V., Merino G., Lucas R., Morales J.C., Tomás-Barberán F., Álvarez A.I., Espín J.C. The gut microbiota ellagic acid-derived metabolite urolithin A and its sulfate conjugate are substrates for the drug efflux transporter breast cancer resistance protein (ABCG2/BCRP). J. Agic. Food Chem. 2013, 61:4352-4359.
    • (2013) J. Agic. Food Chem. , vol.61 , pp. 4352-4359
    • González-Sarrías, A.1    Miguel, V.2    Merino, G.3    Lucas, R.4    Morales, J.C.5    Tomás-Barberán, F.6    Álvarez, A.I.7    Espín, J.C.8
  • 19
    • 84949991156 scopus 로고    scopus 로고
    • Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism
    • González-Sarrías A., Núñez-Sánchez M.A., García-Villalba R., Tomás-Barberán F.A., Espín J.C. Antiproliferative activity of the ellagic acid-derived gut microbiota isourolithin A and comparison with its urolithin A isomer: the role of cell metabolism. Eur. J. Nutr. 2015, 10.1007/s00394-015-1131-7.
    • (2015) Eur. J. Nutr.
    • González-Sarrías, A.1    Núñez-Sánchez, M.A.2    García-Villalba, R.3    Tomás-Barberán, F.A.4    Espín, J.C.5
  • 20
    • 84952684929 scopus 로고    scopus 로고
    • Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key associated molecular hallmarks: microRNA-cell specific induction of CDKN1A (p21) as a common mechanism involved
    • González-Sarrías A., Núñez-Sánchez M.A., Tomé-Carneiro J., Tomás-Barberán F.A., García-Conesa M.T., Espín J.C. Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key associated molecular hallmarks: microRNA-cell specific induction of CDKN1A (p21) as a common mechanism involved. Mol. Nutr. Food Res. 2015, 10.1002/mnfr.201500780.
    • (2015) Mol. Nutr. Food Res.
    • González-Sarrías, A.1    Núñez-Sánchez, M.A.2    Tomé-Carneiro, J.3    Tomás-Barberán, F.A.4    García-Conesa, M.T.5    Espín, J.C.6
  • 21
    • 84929485270 scopus 로고    scopus 로고
    • The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells
    • González-Sarrías A., Tomé-Carneiro J., Bellesia A., Tomás-Barberán F.A., Espín J.C. The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells. Food Funct. 2015, 6:1460-1469.
    • (2015) Food Funct. , vol.6 , pp. 1460-1469
    • González-Sarrías, A.1    Tomé-Carneiro, J.2    Bellesia, A.3    Tomás-Barberán, F.A.4    Espín, J.C.5
  • 22
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang E.H., Hynes M.J., Zhang T., Ginestier C., Dontu G., Appelman H., Fields J.Z., Wicha M.S., Boman B.M. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res. 2009, 69:3382-3389.
    • (2009) Cancer Res. , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6    Fields, J.Z.7    Wicha, M.S.8    Boman, B.M.9
  • 23
    • 85018215061 scopus 로고    scopus 로고
    • Colorectal cancer stem cell and chemoresistant colorectal cancer cell phenotypes and increased sensitivity to Notch pathway inhibitor
    • Huang R., Wang G., Song Y., Tang Q., You Q., Liu Z., Chen Y., Zhang Q., Li Y., Muhammand S., Wang X. Colorectal cancer stem cell and chemoresistant colorectal cancer cell phenotypes and increased sensitivity to Notch pathway inhibitor. Mol. Med. Rep. 2015, 12:2417-2424.
    • (2015) Mol. Med. Rep. , vol.12 , pp. 2417-2424
    • Huang, R.1    Wang, G.2    Song, Y.3    Tang, Q.4    You, Q.5    Liu, Z.6    Chen, Y.7    Zhang, Q.8    Li, Y.9    Muhammand, S.10    Wang, X.11
  • 27
    • 84942906792 scopus 로고    scopus 로고
    • Identification of thiotrepton as a novel therapeutic agent that targets human colon cancer stem cells
    • Ju S.Y., Huang C.Y.F., Huang W.C., Su Y. Identification of thiotrepton as a novel therapeutic agent that targets human colon cancer stem cells. Cell Death Dis. 2015, 6. e18016.
    • (2015) Cell Death Dis. , vol.6
    • Ju, S.Y.1    Huang, C.Y.F.2    Huang, W.C.3    Su, Y.4
  • 32
    • 79958160079 scopus 로고    scopus 로고
    • Implications of stem cell theory for chemoprevention by natural dietary compounds
    • Li Y., Wicha M.S., Schwartz S.J., Sun D. Implications of stem cell theory for chemoprevention by natural dietary compounds. J. Nutr. Biochem. 2011, 22:799-806.
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 799-806
    • Li, Y.1    Wicha, M.S.2    Schwartz, S.J.3    Sun, D.4
  • 34
    • 84867895444 scopus 로고    scopus 로고
    • Epigallocatechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines
    • Lin C.H., Shen Y.A., Hung P.H., Yu Y.B., Chen Y.J. Epigallocatechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines. BMC Complemen. Altern. Med. 2012, 12:201.
    • (2012) BMC Complemen. Altern. Med. , vol.12 , pp. 201
    • Lin, C.H.1    Shen, Y.A.2    Hung, P.H.3    Yu, Y.B.4    Chen, Y.J.5
  • 35
    • 84961942167 scopus 로고    scopus 로고
    • Chemotherapy targeting cancer stem cells
    • Liu H., Lv L., Yang K. Chemotherapy targeting cancer stem cells. Am. J. Cancer Res. 2015, 5:880-893.
    • (2015) Am. J. Cancer Res. , vol.5 , pp. 880-893
    • Liu, H.1    Lv, L.2    Yang, K.3
  • 36
    • 84858608410 scopus 로고    scopus 로고
    • Cancer stem cells: impact, heterogeneity, and uncertainty
    • Magee J.A., Piskounova E., Morrison S.J. Cancer stem cells: impact, heterogeneity, and uncertainty. Cancer Cell 2012, 21:283-296.
    • (2012) Cancer Cell , vol.21 , pp. 283-296
    • Magee, J.A.1    Piskounova, E.2    Morrison, S.J.3
  • 37
    • 84876489727 scopus 로고    scopus 로고
    • Cancer stem cells: the challenges ahead
    • Medema J.P. Cancer stem cells: the challenges ahead. Nat. Cell Biol. 2013, 15:338-344.
    • (2013) Nat. Cell Biol. , vol.15 , pp. 338-344
    • Medema, J.P.1
  • 38
    • 84856710446 scopus 로고    scopus 로고
    • Cancer stem cell sorting from colorectal cancer cell lines by sedimentation field flow fractionation
    • Mélin C., Perraud A., Akil H., Jauberteau M.O., Cardot P., Mathonnet M., Battu S. Cancer stem cell sorting from colorectal cancer cell lines by sedimentation field flow fractionation. Anal. Chem. 2012, 84:1549-1556.
    • (2012) Anal. Chem. , vol.84 , pp. 1549-1556
    • Mélin, C.1    Perraud, A.2    Akil, H.3    Jauberteau, M.O.4    Cardot, P.5    Mathonnet, M.6    Battu, S.7
  • 39
    • 84901860196 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells
    • Mineva N.D., Paulson K.E., Naber S.P., Yee A.S., Sonenshein G.E. Epigallocatechin-3-gallate inhibits stem-like inflammatory breast cancer cells. PLoS One 2013, 8. e73464.
    • (2013) PLoS One , vol.8
    • Mineva, N.D.1    Paulson, K.E.2    Naber, S.P.3    Yee, A.S.4    Sonenshein, G.E.5
  • 40
    • 84863252739 scopus 로고    scopus 로고
    • Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells
    • Montales M.T., Rahal O.M., Kang J., Rogers T.J., Prior R.L., Wu X., Simmen R.C. Repression of mammosphere formation of human breast cancer cells by soy isoflavone genistein and blueberry polyphenolic acids suggests diet-mediated targeting of cancer stem-like/progenitor cells. Carcinogenesis 2012, 33:652-660.
    • (2012) Carcinogenesis , vol.33 , pp. 652-660
    • Montales, M.T.1    Rahal, O.M.2    Kang, J.3    Rogers, T.J.4    Prior, R.L.5    Wu, X.6    Simmen, R.C.7
  • 41
    • 79960565120 scopus 로고    scopus 로고
    • Combination of dasatinib and curcumin eliminates chemo-resistance colon cancer cells
    • Nautiyal J., Kanwar S.S., Yu Y., Majumdar A.P.N. Combination of dasatinib and curcumin eliminates chemo-resistance colon cancer cells. J. Mol. Signal. 2011, 6:7.
    • (2011) J. Mol. Signal. , vol.6 , pp. 7
    • Nautiyal, J.1    Kanwar, S.S.2    Yu, Y.3    Majumdar, A.P.N.4
  • 42
    • 84907999055 scopus 로고    scopus 로고
    • Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cells
    • Nishi M., Akutsu H., Kudoh A., Kimura H., Yamamoto N., Umezawa A., Lee S.W., Ryo A. Induced cancer stem-like cells as a model for biological screening and discovery of agents targeting phenotypic traits of cancer stem cells. Oncotarget 2014, 5:8665-8680.
    • (2014) Oncotarget , vol.5 , pp. 8665-8680
    • Nishi, M.1    Akutsu, H.2    Kudoh, A.3    Kimura, H.4    Yamamoto, N.5    Umezawa, A.6    Lee, S.W.7    Ryo, A.8
  • 48
    • 84940773386 scopus 로고    scopus 로고
    • Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibits LPS-induced inflammation in RAW 264.7 murine macrophages
    • Piwowarski J.P., Kiss A.K., Granica S., Moeslinger T. Urolithins, gut microbiota-derived metabolites of ellagitannins, inhibits LPS-induced inflammation in RAW 264.7 murine macrophages. Mol. Nutr. Food Res. 2015, 59:2168-2177.
    • (2015) Mol. Nutr. Food Res. , vol.59 , pp. 2168-2177
    • Piwowarski, J.P.1    Kiss, A.K.2    Granica, S.3    Moeslinger, T.4
  • 49
    • 33644826473 scopus 로고    scopus 로고
    • Roots and stems: stem cells in cancer
    • Polyak K., Hahn W.C. Roots and stems: stem cells in cancer. Nat. Med. 2005, 11:296-300.
    • (2005) Nat. Med. , vol.11 , pp. 296-300
    • Polyak, K.1    Hahn, W.C.2
  • 52
    • 84930804992 scopus 로고    scopus 로고
    • HCT116 colonospheres shows elevated expression of hTERT and β-catenin protein - a short report
    • Saha A., Shree Padhi S., Roy S., Banerjee B. HCT116 colonospheres shows elevated expression of hTERT and β-catenin protein - a short report. J. Stem Cells 2014, 9:243-251.
    • (2014) J. Stem Cells , vol.9 , pp. 243-251
    • Saha, A.1    Shree Padhi, S.2    Roy, S.3    Banerjee, B.4
  • 54
    • 77950671986 scopus 로고    scopus 로고
    • Effects of fruit ellagitannin extracts, ellagic acid and their colonic metabolite, urolithin A, on Wnt signaling
    • Sharma M., Li L., Celver J., Killian C., Koovor A., Seeram N.P. Effects of fruit ellagitannin extracts, ellagic acid and their colonic metabolite, urolithin A, on Wnt signaling. J. Agric. Food Chem. 2010, 58:3965-3969.
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 3965-3969
    • Sharma, M.1    Li, L.2    Celver, J.3    Killian, C.4    Koovor, A.5    Seeram, N.P.6
  • 55
    • 84867837899 scopus 로고    scopus 로고
    • ALDH as marker for enriching tumorigenic human colonic stem cells
    • Shenoy A., Butterworth E., Huang E.H. ALDH as marker for enriching tumorigenic human colonic stem cells. Methods Mol. Biol. 2012, 916:373-385.
    • (2012) Methods Mol. Biol. , vol.916 , pp. 373-385
    • Shenoy, A.1    Butterworth, E.2    Huang, E.H.3
  • 56
    • 84904437984 scopus 로고    scopus 로고
    • Ellagic acid metabolism by human gut microbiota: consistent observation of three urolithins phenotypes in intervention trials, independent of food source, age and health status
    • Tomás-Barberán F.A., García-Villalba R., González-Sarrías A., Selma M.V., Espín J.C. Ellagic acid metabolism by human gut microbiota: consistent observation of three urolithins phenotypes in intervention trials, independent of food source, age and health status. J. Agric. Food Chem. 2014, 62:6535-6538.
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 6535-6538
    • Tomás-Barberán, F.A.1    García-Villalba, R.2    González-Sarrías, A.3    Selma, M.V.4    Espín, J.C.5
  • 58
    • 70349100257 scopus 로고    scopus 로고
    • CD133 as a marker for cancer stem cells: progresses and concerns
    • Wu Y., Wu P.Y. CD133 as a marker for cancer stem cells: progresses and concerns. Stem Cells Dev. 2009, 18:1127-1134.
    • (2009) Stem Cells Dev. , vol.18 , pp. 1127-1134
    • Wu, Y.1    Wu, P.Y.2
  • 59
    • 84946738071 scopus 로고    scopus 로고
    • Resveratrol inhibits cell proliferation and up-regulates MICA/B expression in human colon cancer stem cells
    • Yang J., Liu J., Lyu X., Fei S. Resveratrol inhibits cell proliferation and up-regulates MICA/B expression in human colon cancer stem cells. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2015, 31:889-893.
    • (2015) Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi , vol.31 , pp. 889-893
    • Yang, J.1    Liu, J.2    Lyu, X.3    Fei, S.4


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