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Volumn 27, Issue 5, 2012, Pages 624-635

The microbiota and its metabolites in colonic mucosal health and cancer risk

Author keywords

Allergy and immunology; Autoimmune diseases; Colon; Colonic neoplasms; Fatty acids; Inflammation; Inflammatory bowel diseases; Irritable bowel syndrome; Metagenome; Obesity

Indexed keywords

ACETIC ACID; BUTYRIC ACID; PROPIONIC ACID;

EID: 84872677660     PISSN: 08845336     EISSN: 19412452     Source Type: Journal    
DOI: 10.1177/0884533612452012     Document Type: Review
Times cited : (100)

References (110)
  • 1
    • 33745594044 scopus 로고    scopus 로고
    • The gut flora as a forgotten organ
    • O'Hara AM, Shanahan F. The gut flora as a forgotten organ. EMBO Rep. 2006;7(7):688-693.
    • (2006) EMBO Rep. , vol.7 , Issue.7 , pp. 688-693
    • O'Hara, A.M.1    Shanahan, F.2
  • 2
    • 20544444045 scopus 로고    scopus 로고
    • Diversity of the human intestinal microbial flora
    • Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora. Science. 2005;308(5728):1635-1638.
    • (2005) Science. , vol.308 , Issue.5728 , pp. 1635-1638
    • Eckburg, P.B.1    Bik, E.M.2    Bernstein, C.N.3
  • 3
    • 32944466887 scopus 로고    scopus 로고
    • Ecological and evolutionary forces shaping microbial diversity in the human intestine
    • Ley RE, Peterson DA, Gordon JI. Ecological and evolutionary forces shaping microbial diversity in the human intestine. Cell. 2006;124(4):837-848.
    • (2006) Cell. , vol.124 , Issue.4 , pp. 837-848
    • Ley, R.E.1    Peterson, D.A.2    Gordon, J.I.3
  • 4
    • 0032956143 scopus 로고    scopus 로고
    • Developmental microbial ecology of the neonatal gastrointestinal tract
    • Mackie RL, Sghir A, Gaskins HR. Developmental microbial ecology of the neonatal gastrointestinal tract. Am J Clin Nutr. 1999;69(5):1035S-1045S.
    • (1999) Am J Clin Nutr. , vol.69 , Issue.5
    • Mackie, R.L.1    Sghir, A.2    Gaskins, H.R.3
  • 6
    • 60549086580 scopus 로고    scopus 로고
    • Human gut microbiota in obesity and after gastric bypass
    • Zhang H, Di Baise JK, Zuccolo A, et al. Human gut microbiota in obesity and after gastric bypass. Proc Natl Acad Sci USA. 2009;106(7):2365-2370.
    • (2009) Proc Natl Acad Sci USA. , vol.106 , Issue.7 , pp. 2365-2370
    • Zhang, H.1    Di Baise, J.K.2    Zuccolo, A.3
  • 8
    • 23944495106 scopus 로고    scopus 로고
    • Metagenomics for studying unculturable microorganisms: Cutting the Gordian knot
    • Schloss PD, Handelsman J. Metagenomics for studying unculturable microorganisms: cutting the Gordian knot. Genome Biol. 2005;6(8):229.
    • (2005) Genome Biol. , vol.6 , Issue.8 , pp. 229
    • Schloss, P.D.1    Handelsman, J.2
  • 9
    • 33750719994 scopus 로고    scopus 로고
    • Global systems biology, personalized medicine and molecular epidemiology
    • Nicholson JK. Global systems biology, personalized medicine and molecular epidemiology. Mol Syst Biol. 2006;2:52.
    • (2006) Mol Syst Biol. , vol.2 , pp. 52
    • Nicholson, J.K.1
  • 10
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • Qin J, Li R, Raes J, et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature. 2010;464(7285):59-65.
    • (2010) Nature. , vol.464 , Issue.7285 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3
  • 11
    • 79551559546 scopus 로고    scopus 로고
    • Current concepts of the intestinal microbiota and the pathogenesis of infection
    • Wardwell LH, Huttenhower C, Garrett WS. Current concepts of the intestinal microbiota and the pathogenesis of infection. Curr Infect Dis Rep. 2011;13(1):28-34.
    • (2011) Curr Infect Dis Rep. , vol.13 , Issue.1 , pp. 28-34
    • Wardwell, L.H.1    Huttenhower, C.2    Garrett, W.S.3
  • 12
    • 70350310104 scopus 로고    scopus 로고
    • Products of the colonic microbiota mediate the effects of diet on colon cancer risk
    • O'Keefe SJ, Ou J, Aufreiter S, et al. Products of the colonic microbiota mediate the effects of diet on colon cancer risk. JNutr. 2009;139(11):2044-2048.
    • (2009) JNutr. , vol.139 , Issue.11 , pp. 2044-2048
    • O'Keefe, S.J.1    Ou, J.2    Aufreiter, S.3
  • 13
    • 0028476745 scopus 로고
    • The colon as a metabolic organ
    • O'Keefe SJ. The colon as a metabolic organ. 5 Afr Med J. 1994;84(7):376-377.
    • (1994) 5 Afr Med J. , vol.84 , Issue.7 , pp. 376-377
    • O'Keefe, S.J.1
  • 14
    • 0031812434 scopus 로고    scopus 로고
    • Presidential address: Gastrointestinal illness and the biopsychosocial model
    • Drossman DA. Presidential address: gastrointestinal illness and the biopsychosocial model. Psychosom Med. 1998;60(3):258-267.
    • (1998) Psychosom Med. , vol.60 , Issue.3 , pp. 258-267
    • Drossman, D.A.1
  • 15
    • 77950202391 scopus 로고    scopus 로고
    • Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium
    • Bailey MT, Dowd SE, Parry NM, Galley JD, Schauer DB, Lyte M. Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by Citrobacter rodentium. Infect Immun. 2010;78(4):1509-1519.
    • (2010) Infect Immun. , vol.78 , Issue.4 , pp. 1509-1519
    • Bailey, M.T.1    Dowd, S.E.2    Parry, N.M.3    Galley, J.D.4    Schauer, D.B.5    Lyte, M.6
  • 16
    • 50649101119 scopus 로고    scopus 로고
    • The gut microbiota predispose to the pathophysiology of acute postradiotherapy diarrhea
    • Manichanh C, Varela E, Martinez C, et al. The gut microbiota predispose to the pathophysiology of acute postradiotherapy diarrhea. Am J Gastroenterol. 2008;103(7):1754-1761.
    • (2008) Am J Gastroenterol. , vol.103 , Issue.7 , pp. 1754-1761
    • Manichanh, C.1    Varela, E.2    Martinez, C.3
  • 17
    • 80051545971 scopus 로고    scopus 로고
    • Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk
    • Li JV, Ashrafian H, Bueter M, et al. Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. Gut. 2011;60(9):1214-1223.
    • (2011) Gut. , vol.60 , Issue.9 , pp. 1214-1223
    • Li, J.V.1    Ashrafian, H.2    Bueter, M.3
  • 18
    • 33846078440 scopus 로고    scopus 로고
    • Why do African Americans get more colon cancer than native Africans?
    • O'Keefe SJ, Chung D, Mahmoud N, et al. Why do African Americans get more colon cancer than native Africans? J Nutr. 2007;137(1) (suppl):175S-182S.
    • (2007) J Nutr. , vol.137 , Issue.1 SUPPL.
    • O'Keefe, S.J.1    Chung, D.2    Mahmoud, N.3
  • 19
    • 23044491563 scopus 로고    scopus 로고
    • Introducing inulin-type fructans
    • Roberfroid MB. Introducing inulin-type fructans. Br J Nutr. 2005;93(1):S13-S25.
    • (2005) Br J Nutr. , vol.93 , Issue.1
    • Roberfroid, M.B.1
  • 20
    • 0037509909 scopus 로고    scopus 로고
    • Regulation of short-chain fatty acid production
    • Macfarlane S, Macfarlane GT. Regulation of short-chain fatty acid production. Proc Nutr Soc. 2003;62(1):67-72.
    • (2003) Proc Nutr Soc. , vol.62 , Issue.1 , pp. 67-72
    • Macfarlane, S.1    Macfarlane, G.T.2
  • 21
    • 0019838759 scopus 로고
    • Short chain fatty acids in the human colon
    • Cummings JH. Short chain fatty acids in the human colon. Gut. 1981;22(9):763-779.
    • (1981) Gut. , vol.22 , Issue.9 , pp. 763-779
    • Cummings, J.H.1
  • 22
    • 84863119810 scopus 로고    scopus 로고
    • Association between low colonic short-chain fatty acids and high bile acids in high colon cancer risk populations
    • Ou J, De Lany JP, Zhang M, Sharma S, O'Keefe SJ. Association between low colonic short-chain fatty acids and high bile acids in high colon cancer risk populations. Nutr Cancer. 2012;64(1):34-40.
    • (2012) Nutr Cancer. , vol.64 , Issue.1 , pp. 34-40
    • Ou, J.1    De Lany, J.P.2    Zhang, M.3    Sharma, S.4    O'Keefe, S.J.5
  • 23
    • 0028918389 scopus 로고
    • Digestive processes in the human colon
    • Nordgaard I, Mortensen PB. Digestive processes in the human colon. Nutrition. 1995;11(1):37-45.
    • (1995) Nutrition. , vol.11 , Issue.1 , pp. 37-45
    • Nordgaard, I.1    Mortensen, P.B.2
  • 24
    • 0035039543 scopus 로고    scopus 로고
    • Effect of resistant starch on potential biomarkers for colonic cancer risk in patients with colonic adenomas: A controlled trial
    • Grubben MJ, Van Den Braak CC, Essenberg M, et al. Effect of resistant starch on potential biomarkers for colonic cancer risk in patients with colonic adenomas: a controlled trial. Dig Dis Sci. 2001;46(4):750-756.
    • (2001) Dig Dis Sci. , vol.46 , Issue.4 , pp. 750-756
    • Grubben, M.J.1    Van Den Braak, C.C.2    Essenberg, M.3
  • 25
    • 0021221584 scopus 로고
    • Calcium inhibits the damaging and compensatory proliferative effects of fatty acids on mouse colon epithelium
    • Wargovich MJ, Eng VW, Newmark HL. Calcium inhibits the damaging and compensatory proliferative effects of fatty acids on mouse colon epithelium. Cancer Lett. 1984;23(3):253-258.
    • (1984) Cancer Lett. , vol.23 , Issue.3 , pp. 253-258
    • Wargovich, M.J.1    Eng, V.W.2    Newmark, H.L.3
  • 26
    • 0141645569 scopus 로고    scopus 로고
    • Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E (1) and E (2) production by intestinal myofibroblasts
    • Willemsen LE, Koetsier MA, Van Deventer SJ, Van Tol EA. Short chain fatty acids stimulate epithelial mucin 2 expression through differential effects on prostaglandin E (1) and E (2) production by intestinal myofibroblasts. Gut. 2003;52(10):1442-1447.
    • (2003) Gut. , vol.52 , Issue.10 , pp. 1442-1447
    • Willemsen, L.E.1    Koetsier, M.A.2    Van Deventer, S.J.3    Van Tol, E.A.4
  • 27
    • 74049124329 scopus 로고    scopus 로고
    • Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E (2) and cytokines
    • Cox MA, Jackson J, Stanton M, et al. Short-chain fatty acids act as antiinflammatory mediators by regulating prostaglandin E (2) and cytokines. World J Gastmenterol. 2009;15(44):5549-5557.
    • (2009) World J Gastmenterol. , vol.15 , Issue.44 , pp. 5549-5557
    • Cox, M.A.1    Jackson, J.2    Stanton, M.3
  • 28
    • 3042648076 scopus 로고    scopus 로고
    • Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets
    • discussion 222-223
    • Bartholome AL, Albin DM, Baker DH, Holst JJ, Tappenden KA. Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. JPEN J Parenter Enteral Nutr. 2004;28(4):210-222; discussion 222-223.
    • (2004) JPEN J Parenter Enteral Nutr. , vol.28 , Issue.4 , pp. 210-222
    • Bartholome, A.L.1    Albin, D.M.2    Baker, D.H.3    Holst, J.J.4    Tappenden, K.A.5
  • 29
    • 34247371381 scopus 로고    scopus 로고
    • Understanding the effects of diet on bacterial metabolism in the large intestine
    • Louis P, Scott KP, Duncan SH, Flint HJ. Understanding the effects of diet on bacterial metabolism in the large intestine. J Appl Microbiol. 2007;102(5):1197-1208.
    • (2007) J Appl Microbiol. , vol.102 , Issue.5 , pp. 1197-1208
    • Louis, P.1    Scott, K.P.2    Duncan, S.H.3    Flint, H.J.4
  • 30
    • 0019940133 scopus 로고
    • Utilization of nutrients by isolated epithelial cells of the rat colon
    • Roediger WE. Utilization of nutrients by isolated epithelial cells of the rat colon. Gastroenterology. 1982, 83(2):424-429.
    • (1982) Gastroenterology , vol.83 , Issue.2 , pp. 424-429
    • Roediger, W.E.1
  • 31
    • 31344443290 scopus 로고    scopus 로고
    • An overview of apoptosis and the prevention of colorectal cancer
    • Watson AJ. An overview of apoptosis and the prevention of colorectal cancer. Crit Rev Oncol Hematol. 2006;57(2):107-121.
    • (2006) Crit Rev Oncol Hematol. , vol.57 , Issue.2 , pp. 107-121
    • Watson, A.J.1
  • 32
    • 0036846899 scopus 로고    scopus 로고
    • Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats
    • Rodriguez-Cabezas ME, Galvez J, Lorente MD, et al. Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. J Nutr. 2002;132(11):3263-3271.
    • (2002) J Nutr. , vol.132 , Issue.11 , pp. 3263-3271
    • Rodriguez-Cabezas, M.E.1    Galvez, J.2    Lorente, M.D.3
  • 33
    • 33746233585 scopus 로고    scopus 로고
    • Dietary fiber enhances a tumor suppressor signaling pathway in the gut
    • Nguyen KA, Cao Y, Chen JR, Townsend CM Jr, Ko TC. Dietary fiber enhances a tumor suppressor signaling pathway in the gut. Ann Surg. 2006;243(5):619-625.
    • (2006) Ann Surg. , vol.243 , Issue.5 , pp. 619-625
    • Nguyen, K.A.1    Cao, Y.2    Chen, J.R.3    Townsend Jr., C.M.4    Ko, T.C.5
  • 34
    • 35848936502 scopus 로고    scopus 로고
    • Dietary modulation of colon cancer risk
    • Kim YS, Milner JA. Dietary modulation of colon cancer risk. J Nutr. 2007;137(11) (suppl):2576S-2579S.
    • (2007) J Nutr. , vol.137 , Issue.11 SUPPL.
    • Kim, Y.S.1    Milner, J.A.2
  • 36
    • 0038676409 scopus 로고    scopus 로고
    • Inhibition of histone deacetylase activity by butyrate
    • Davie JR. Inhibition of histone deacetylase activity by butyrate. J Nutr. 2003;133(7) (suppl):2485S-2493S.
    • (2003) J Nutr. , vol.133 , Issue.7 SUPPL.
    • Davie, J.R.1
  • 37
    • 79960895388 scopus 로고    scopus 로고
    • Microbial induction of immunity, inflammation, and cancer
    • Greer JB, O'Keefe SJ. Microbial induction of immunity, inflammation, and cancer. Front Physiol. 2011;1:168.
    • (2011) Front Physiol. , vol.1 , pp. 168
    • Greer, J.B.1    O'Keefe, S.J.2
  • 38
    • 0142247518 scopus 로고    scopus 로고
    • Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate
    • Ebert MN, Klinder A, Peters WH, et al. Expression of glutathione S-transferases (GSTs) in human colon cells and inducibility of GSTM2 by butyrate. Carcinogenesis. 2003;24(10):1637-1644.
    • (2003) Carcinogenesis. , vol.24 , Issue.10 , pp. 1637-1644
    • Ebert, M.N.1    Klinder, A.2    Peters, W.H.3
  • 39
    • 0035712906 scopus 로고    scopus 로고
    • Sodium butyrate enhances complement-mediated cell injury via down-regulation of decayaccelerating factor expression in colonic cancer cells
    • Andoh A, Shimada M, Araki Y, Fujiyama Y, Bamba T. Sodium butyrate enhances complement-mediated cell injury via down-regulation of decayaccelerating factor expression in colonic cancer cells. Cancer Immunol Immunother. 2002;50(12):663-672.
    • (2002) Cancer Immunol Immunother. , vol.50 , Issue.12 , pp. 663-672
    • Andoh, A.1    Shimada, M.2    Araki, Y.3    Fujiyama, Y.4    Bamba, T.5
  • 40
    • 0037462884 scopus 로고    scopus 로고
    • Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-lalpha nuclear translocation
    • Zgouras D, Wachtershauser A, Frings D, Stein J. Butyrate impairs intestinal tumor cell-induced angiogenesis by inhibiting HIF-lalpha nuclear translocation. Biochem Biophys Res Commun. 2003;300(4):832-838.
    • (2003) Biochem Biophys Res Commun. , vol.300 , Issue.4 , pp. 832-838
    • Zgouras, D.1    Wachtershauser, A.2    Frings, D.3    Stein, J.4
  • 42
    • 33846793153 scopus 로고    scopus 로고
    • Peptide YY and proglucagon mRNA expression patterns and regulation in the gut
    • Zhou J, Hegsted M, McCutcheon KL, et al. Peptide YY and proglucagon mRNA expression patterns and regulation in the gut. Obesity (Silver Spring). 2006;14(4):683-689.
    • (2006) Obesity (Silver Spring) , vol.14 , Issue.4 , pp. 683-689
    • Zhou, J.1    Hegsted, M.2    McCutcheon, K.L.3
  • 43
    • 0026519107 scopus 로고
    • Stable isotope model for estimating colonic acetate production in premature infants
    • Kien CL, Kepner J, Grotjohn K, Ault K, McClead RE. Stable isotope model for estimating colonic acetate production in premature infants. Gastroenterology. 1992;102(5):1458-1466.
    • (1992) Gastroenterology , vol.102 , Issue.5 , pp. 1458-1466
    • Kien, C.L.1    Kepner, J.2    Grotjohn, K.3    Ault, K.4    McClead, R.E.5
  • 44
    • 0033392917 scopus 로고    scopus 로고
    • Zonation of acetate labeling across the liver: Implications for studies of lipogenesis by MIDA
    • Puchowicz MA, Bederman IR, Comte B, et al. Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA. Am J Physiol. 1999;277(6, pt 1):E1022-E1027.
    • (1999) Am J Physiol. , vol.277 , Issue.6 PART 1
    • Puchowicz, M.A.1    Bederman, I.R.2    Comte, B.3
  • 45
    • 0025360099 scopus 로고
    • Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers
    • Venter CS, Vorster HH, Cummings JH. Effects of dietary propionate on carbohydrate and lipid metabolism in healthy volunteers. Am J Gastroenterol. 1990;85(5):549-553.
    • (1990) Am J Gastroenterol. , vol.85 , Issue.5 , pp. 549-553
    • Venter, C.S.1    Vorster, H.H.2    Cummings, J.H.3
  • 47
    • 78650179808 scopus 로고    scopus 로고
    • Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
    • Al-Lahham SH, Peppelenbosch MP, Roelofsen H, Vonk RJ, Venema K. Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. Biochim Biophys Acta. 2010;1801(11):1175-1183.
    • (2010) Biochim Biophys Acta. , vol.1801 , Issue.11 , pp. 1175-1183
    • Al-Lahham, S.H.1    Peppelenbosch, M.P.2    Roelofsen, H.3    Vonk, R.J.4    Venema, K.5
  • 48
    • 0027534677 scopus 로고
    • Nonsteroidal antiinflammatory agents, XVII: Inhibition of bovine cyclooxygenase and 5-lipoxygenase by N-alkyldiphenylpyrrolyl acetic and propionic acid derivatives
    • Dannhardt G, Lehr M. Nonsteroidal antiinflammatory agents, XVII: inhibition of bovine cyclooxygenase and 5-lipoxygenase by N- alkyldiphenylpyrrolyl acetic and propionic acid derivatives. Arch Pharm (Weinheim), 1993;326(3):157-162.
    • (1993) Arch Pharm (Weinheim) , vol.326 , Issue.3 , pp. 157-162
    • Dannhardt, G.1    Lehr, M.2
  • 49
    • 68049092959 scopus 로고    scopus 로고
    • Propionate reduces the cytokine-induced VCAM-1 and ICAM-1 expression by inhibiting nuclear factor-kappa B (NF-kappaB) activation
    • Zapolska-Downar D, Naruszewicz M. Propionate reduces the cytokine-induced VCAM-1 and ICAM-1 expression by inhibiting nuclear factor-kappa B (NF-kappaB) activation. J Physiol Pharmacol. 2009;60(2):123-131.
    • (2009) J Physiol Pharmacol. , vol.60 , Issue.2 , pp. 123-131
    • Zapolska-Downar, D.1    Naruszewicz, M.2
  • 50
    • 0036885883 scopus 로고    scopus 로고
    • Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA
    • Lawhon SD, Maurer R, Suyemoto M, Altier C. Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA. Mol Microbiol. 2002;46(5):1451-1464.
    • (2002) Mol Microbiol. , vol.46 , Issue.5 , pp. 1451-1464
    • Lawhon, S.D.1    Maurer, R.2    Suyemoto, M.3    Altier, C.4
  • 51
    • 47649097511 scopus 로고    scopus 로고
    • Satiety effects of a dairy beverage fermented with propionic acid bacteria
    • Ruijschop R M A J, Boelrijk A E M, Te Giffela MC. Satiety effects of a dairy beverage fermented with propionic acid bacteria. Int Dairy J. 2008;18:945-950.
    • (2008) Int Dairy J. , vol.18 , pp. 945-950
    • Ruijschop, R.M.A.J.1    Boelrijk, A.E.M.2    Te Giffela, M.C.3
  • 52
    • 77951222945 scopus 로고    scopus 로고
    • Regulation of adipokine production in human adipose tissue by propionic acid
    • Al-Lahham SH, Roelofsen H, Priebe M, et al. Regulation of adipokine production in human adipose tissue by propionic acid. Eur J Clin Invest. 2010;40(5):401-407.
    • (2010) Eur J Clin Invest. , vol.40 , Issue.5 , pp. 401-407
    • Al-Lahham, S.H.1    Roelofsen, H.2    Priebe, M.3
  • 53
    • 0031709152 scopus 로고    scopus 로고
    • Development and maintenance of the gut-associated lymphoid tissue (GALT): The roles of enteric bacteria and viruses
    • Cebra JJ, Periwal SB, Lee G, Lee F, Shroff KE. Development and maintenance of the gut-associated lymphoid tissue (GALT): the roles of enteric bacteria and viruses. Dev Immunol. 1998;6(1-2):13-18.
    • (1998) Dev Immunol. , vol.6 , Issue.1-2 , pp. 13-18
    • Cebra, J.J.1    Periwal, S.B.2    Lee, G.3    Lee, F.4    Shroff, K.E.5
  • 55
    • 75649093343 scopus 로고    scopus 로고
    • Toll-like receptor signalling in the intestinal epithelium: How bacterial recognition shapes intestinal function
    • Abreu MT. Toll-like receptor signalling in the intestinal epithelium: how bacterial recognition shapes intestinal function. Nat Rev Immunol. 2010;10(2):131-144.
    • (2010) Nat Rev Immunol. , vol.10 , Issue.2 , pp. 131-144
    • Abreu, M.T.1
  • 57
    • 36549075219 scopus 로고    scopus 로고
    • Nutrition and colonic health: The critical role of the microbiota
    • O'Keefe SJ. Nutrition and colonic health: the critical role of the microbiota. Curr Opin Gastroenterol. 2008;24(1). 51-58.
    • (2008) Curr Opin Gastroenterol. , vol.24 , Issue.1 , pp. 51-58
    • O'Keefe, S.J.1
  • 58
    • 0024081511 scopus 로고
    • Competition for hydrogen between sulphate-reducing bacteria and methanogenic bacteria from the human large intestine
    • Gibson GR, Cummings JH, Macfarlane GT. Competition for hydrogen between sulphate-reducing bacteria and methanogenic bacteria from the human large intestine. JAppl Bacteriol. 1988;65(3):241-247.
    • (1988) JAppl Bacteriol. , vol.65 , Issue.3 , pp. 241-247
    • Gibson, G.R.1    Cummings, J.H.2    Macfarlane, G.T.3
  • 60
    • 0027404555 scopus 로고
    • Sulphate reducing bacteria and hydrogen metabolism in the human large intestine
    • Gibson GR, Macfarlane GT, Cummings JH. Sulphate reducing bacteria and hydrogen metabolism in the human large intestine. Gut. 1993;34(4):437-439.
    • (1993) Gut. , vol.34 , Issue.4 , pp. 437-439
    • Gibson, G.R.1    Macfarlane, G.T.2    Cummings, J.H.3
  • 61
    • 0029129169 scopus 로고
    • Role of bile acids in colorectal carcinogenesis
    • Nagengast FM, Gnibben MJ, Van Munster IP. Role of bile acids in colorectal carcinogenesis. Eur J Cancer. 1995;31A(7-8):1067-1070.
    • (1995) Eur J Cancer. , vol.31 A , Issue.7-8 , pp. 1067-1070
    • Nagengast, F.M.1    Gnibben, M.J.2    Van Munster, I.P.3
  • 62
    • 33244467651 scopus 로고    scopus 로고
    • Bile salt biotransformations by human intestinal bacteria
    • Ridlon JM, Kang DJ, Hylemon PB. Bile salt biotransformations by human intestinal bacteria. J Lipid Res. 2006;47(2):241-259.
    • (2006) J Lipid Res. , vol.47 , Issue.2 , pp. 241-259
    • Ridlon, J.M.1    Kang, D.J.2    Hylemon, P.B.3
  • 63
    • 24344479257 scopus 로고    scopus 로고
    • Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors
    • Cheng K, Raufman JP. Bile acid-induced proliferation of a human colon cancer cell line is mediated by transactivation of epidermal growth factor receptors. Biochem Pharmacol. 2005;70(7):1035-1047.
    • (2005) Biochem Pharmacol. , vol.70 , Issue.7 , pp. 1035-1047
    • Cheng, K.1    Raufman, J.P.2
  • 64
    • 77955011833 scopus 로고    scopus 로고
    • Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: Relevance to genomic instability in colon carcinogenesis
    • Payne CM, Crowley-Skillicom C, Bernstein C, Holubec H, Moyer MP, Bernstein H. Hydrophobic bile acid-induced micronuclei formation, mitotic perturbations, and decreases in spindle checkpoint proteins: relevance to genomic instability in colon carcinogenesis. Nutr Cancer. 2010;62(6):825-840.
    • (2010) Nutr Cancer. , vol.62 , Issue.6 , pp. 825-840
    • Payne, C.M.1    Crowley-Skillicom, C.2    Bernstein, C.3    Holubec, H.4    Moyer, M.P.5    Bernstein, H.6
  • 65
    • 48549084602 scopus 로고    scopus 로고
    • Real-time polymerase chain reaction quantification of specific butyrateproducing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer
    • Balamurugan R, Rajendiran E, George S, Samuel GV, Ramakrishna BS. Real-time polymerase chain reaction quantification of specific butyrateproducing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer. J Gastroenterol Hepatol. 2008;23(8, pt 1):1298-1303.
    • (2008) J Gastroenterol Hepatol. , vol.23 , Issue.8 PART 1 , pp. 1298-1303
    • Balamurugan, R.1    Rajendiran, E.2    George, S.3    Samuel, G.V.4    Ramakrishna, B.S.5
  • 66
    • 79551571717 scopus 로고    scopus 로고
    • Microbial dysbiosis in colorectal cancer (CRC) patients
    • Sobhani I, Tap J, Roudot-Thoraval F, et al. Microbial dysbiosis in colorectal cancer (CRC) patients. PLoS One. 2011;6(1):e16393.
    • (2011) PLoS One. , vol.6 , Issue.1
    • Sobhani, I.1    Tap, J.2    Roudot-Thoraval, F.3
  • 67
    • 84856534859 scopus 로고    scopus 로고
    • Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma [published online ahead of print October 18, 2011]
    • doi: 10.1101/gr. 126516.111
    • Castellarin M, Warren RL, Freeman JD, et al. Fusobacterium nucleatum infection is prevalent in human colorectal carcinoma [published online ahead of print October 18, 2011]. Genome Res. doi: 10.1101/gr. 126516.111.
    • Genome Res
    • Castellarin, M.1    Warren, R.L.2    Freeman, J.D.3
  • 68
    • 79251580670 scopus 로고    scopus 로고
    • The inflammatory microenvironment in colorectal neoplasia
    • McLean MH, Murray GI, Stewart KN, et al. The inflammatory microenvironment in colorectal neoplasia. PLoS One. 2011;6(1):e15366.
    • (2011) PLoS One. , vol.6 , Issue.1
    • McLean, M.H.1    Murray, G.I.2    Stewart, K.N.3
  • 69
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S, Rhee KJ, Albesiano E, et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat Med. 2009;15(9):1016-1022.
    • (2009) Nat Med. , vol.15 , Issue.9 , pp. 1016-1022
    • Wu, S.1    Rhee, K.J.2    Albesiano, E.3
  • 70
    • 78651564013 scopus 로고    scopus 로고
    • The association of Streptococcus bovis/gallolyticus with colorectal tumors: The nature and the underlying mechanisms of its etiological role
    • Abdulamir AS, Hafidh RR, Abu Bakar F. The association of Streptococcus bovis/gallolyticus with colorectal tumors: the nature and the underlying mechanisms of its etiological role. J Exp Clin Cancer Res. 2011;30:11.
    • (2011) J Exp Clin Cancer Res. , vol.30 , pp. 11
    • Abdulamir, A.S.1    Hafidh, R.R.2    Abu Bakar, F.3
  • 72
    • 78649854163 scopus 로고    scopus 로고
    • Effect of aspirin and NSAIDs on risk and survival from colorectal cancer
    • Din FV, Theodoratou E, Farrington SM, et al. Effect of aspirin and NSAIDs on risk and survival from colorectal cancer. Gut. 2010;59(12):1670-1679.
    • (2010) Gut. , vol.59 , Issue.12 , pp. 1670-1679
    • Din, F.V.1    Theodoratou, E.2    Farrington, S.M.3
  • 73
    • 0031928730 scopus 로고    scopus 로고
    • Association between intraepithelial Escherichia coli and colorectal cancer
    • Swidsinski A, Khilkin M, Kerjaschki D, et al. Association between intraepithelial Escherichia coli and colorectal cancer. Gastroenterology. 1998;115(2):281-286.
    • (1998) Gastroenterology , vol.115 , Issue.2 , pp. 281-286
    • Swidsinski, A.1    Khilkin, M.2    Kerjaschki, D.3
  • 74
    • 3042712911 scopus 로고    scopus 로고
    • Commensal bacteria, redox stress, and colorectal cancer: Mechanisms and models
    • Huycke MM, Gaskins HR. Commensal bacteria, redox stress, and colorectal cancer: mechanisms and models. Exp Biol Med (Maywood). 2004;229(7):586-597.
    • (2004) Exp Biol Med (Maywood) , vol.229 , Issue.7 , pp. 586-597
    • Huycke, M.M.1    Gaskins, H.R.2
  • 76
    • 40549100384 scopus 로고    scopus 로고
    • Dietary heme injures surface epithelium resulting in hyperproliferation, inhibition of apoptosis and crypt hyperplasia in rat colon
    • De Vogel J, Van-Eck WB, Sesink AL, Jonker-Termont DS, Kleibeuker J, Van Der Meer R. Dietary heme injures surface epithelium resulting in hyperproliferation, inhibition of apoptosis and crypt hyperplasia in rat colon. Carcinogenesis. 2008;29(2):398-403.
    • (2008) Carcinogenesis. , vol.29 , Issue.2 , pp. 398-403
    • De Vogel, J.1    Van-Eck, W.B.2    Sesink, A.L.3    Jonker-Termont, D.S.4    Kleibeuker, J.5    Van Der Meer, R.6
  • 77
    • 33745683853 scopus 로고    scopus 로고
    • Meat mutagens and risk of distal colon adenoma in a cohort of U. S. men
    • Wu K, Giovannucci E, Byrne C, et al. Meat mutagens and risk of distal colon adenoma in a cohort of U. S. men. Cancer Epidemiol Biomarkers Prev. 2006;15(6):1120-1125.
    • (2006) Cancer Epidemiol Biomarkers Prev. , vol.15 , Issue.6 , pp. 1120-1125
    • Wu, K.1    Giovannucci, E.2    Byrne, C.3
  • 78
    • 0034709640 scopus 로고    scopus 로고
    • Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: Implications for colon carcinogenesis
    • McMillan L, Butcher S, Wallis Y, Neoptolemos JP, Lord JM. Bile acids reduce the apoptosis-inducing effects of sodium butyrate on human colon adenoma (AA/C1) cells: implications for colon carcinogenesis. Biochem Biophys Res Commun. 2000;273(1):45-49.
    • (2000) Biochem Biophys Res Commun. , vol.273 , Issue.1 , pp. 45-49
    • McMillan, L.1    Butcher, S.2    Wallis, Y.3    Neoptolemos, J.P.4    Lord, J.M.5
  • 79
    • 13844254867 scopus 로고    scopus 로고
    • Green vegetables, red meat and colon cancer: Chlorophyll prevents the cytotoxic and hyperproliferative effects of haem in rat colon
    • De Vogel J, Jonker-Termont DS, Van Lieshout EM, Katan MB, Van Der Meer R. Green vegetables, red meat and colon cancer: chlorophyll prevents the cytotoxic and hyperproliferative effects of haem in rat colon. Carcinogenesis. 2005;26(2):387-393.
    • (2005) Carcinogenesis. , vol.26 , Issue.2 , pp. 387-393
    • De Vogel, J.1    Jonker-Termont, D.S.2    Van Lieshout, E.M.3    Katan, M.B.4    Van Der Meer, R.5
  • 80
    • 33646417960 scopus 로고    scopus 로고
    • Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats
    • Toden S, Bird AR, Topping DL, Conlon MA. Resistant starch prevents colonic DNA damage induced by high dietary cooked red meat or casein in rats. Cancer Biol Ther. 2006;5(3):267-272.
    • (2006) Cancer Biol Ther. , vol.5 , Issue.3 , pp. 267-272
    • Toden, S.1    Bird, A.R.2    Topping, D.L.3    Conlon, M.A.4
  • 81
    • 1542513850 scopus 로고    scopus 로고
    • Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota
    • Young VB, Schmidt TM. Antibiotic-associated diarrhea accompanied by large-scale alterations in the composition of the fecal microbiota. J Clin Microbiol. 2004;42(3):1203-1206.
    • (2004) J Clin Microbiol. , vol.42 , Issue.3 , pp. 1203-1206
    • Young, V.B.1    Schmidt, T.M.2
  • 82
    • 80051717743 scopus 로고    scopus 로고
    • The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile infection
    • Reeves AE, Theriot CM, Bergin IL, Huffnagle GB, Schloss PD, Young VB. The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile infection. Gut Microbes. 2011;2(3):145-158.
    • (2011) Gut Microbes. , vol.2 , Issue.3 , pp. 145-158
    • Reeves, A.E.1    Theriot, C.M.2    Bergin, I.L.3    Huffnagle, G.B.4    Schloss, P.D.5    Young, V.B.6
  • 83
    • 77951700268 scopus 로고    scopus 로고
    • Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-moc\sAei diarrhea
    • Khoruts A, Dicksved J, Jansson JK, Sadowsky MJ. Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-moc\sAei diarrhea. J Clin Gastroenterol. 2010;44(5):354-360.
    • (2010) J Clin Gastroenterol. , vol.44 , Issue.5 , pp. 354-360
    • Khoruts, A.1    Dicksved, J.2    Jansson, J.K.3    Sadowsky, M.J.4
  • 84
    • 2442563304 scopus 로고    scopus 로고
    • Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences
    • Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology. 2004;126(6):1504-1517.
    • (2004) Gastroenterology , vol.126 , Issue.6 , pp. 1504-1517
    • Loftus Jr., E.V.1
  • 85
    • 0024417450 scopus 로고
    • Hay fever, hygiene, and household size
    • Strachan DP. Hay fever, hygiene, and household size. BMJ. 1989;299(6710):1259-1260.
    • (1989) BMJ. , vol.299 , Issue.6710 , pp. 1259-1260
    • Strachan, D.P.1
  • 86
    • 79955935457 scopus 로고    scopus 로고
    • Intestinal microbiota in inflammatory bowel disease: Friend of foe?
    • Fava F, Danese S. Intestinal microbiota in inflammatory bowel disease: friend of foe? World J Gastroenterol. 2011;17(5):557-566.
    • (2011) World J Gastroenterol. , vol.17 , Issue.5 , pp. 557-566
    • Fava, F.1    Danese, S.2
  • 87
    • 0027456925 scopus 로고
    • Reducing sulfur compounds of the colon impair colonocyte nutrition: Implications for ulcerative colitis
    • Roediger WE, Duncan A, Kapaniris O, Millard S. Reducing sulfur compounds of the colon impair colonocyte nutrition: implications for ulcerative colitis. Gastroenterology. 1993;104(3):802-809.
    • (1993) Gastroenterology , vol.104 , Issue.3 , pp. 802-809
    • Roediger, W.E.1    Duncan, A.2    Kapaniris, O.3    Millard, S.4
  • 88
    • 38149069478 scopus 로고    scopus 로고
    • Reduced diversity in the early fecal microbiota of infants with atopic eczema
    • Wang M, Karlsson C, Olsson C, et al. Reduced diversity in the early fecal microbiota of infants with atopic eczema. J Allergy Clin Immunol. 2008;121(1):129-134.
    • (2008) J Allergy Clin Immunol. , vol.121 , Issue.1 , pp. 129-134
    • Wang, M.1    Karlsson, C.2    Olsson, C.3
  • 89
    • 79955606197 scopus 로고    scopus 로고
    • Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma
    • quiz 1108-1109
    • McLoughlin RM, Mills KH. Influence of gastrointestinal commensal bacteria on the immune responses that mediate allergy and asthma. J Allergy Clin Immunol. 2011;127(5):1097-1107; quiz 1108-1109.
    • (2011) J Allergy Clin Immunol. , vol.127 , Issue.5 , pp. 1097-1107
    • McLoughlin, R.M.1    Mills, K.H.2
  • 90
    • 35148856682 scopus 로고    scopus 로고
    • The role of the intestinal microbiota in the development of atopic disorders
    • Penders J, Stobberingh EE, Van Den Brandt PA, Thijs C. The role of the intestinal microbiota in the development of atopic disorders. Allergy. 2007;62(11):1223-1236.
    • (2007) Allergy , vol.62 , Issue.11 , pp. 1223-1236
    • Penders, J.1    Stobberingh, E.E.2    Van Den Brandt, P.A.3    Thijs, C.4
  • 91
    • 33845404097 scopus 로고    scopus 로고
    • Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing
    • Penders J, Stobberingh EE, Thijs C, et al. Molecular fingerprinting of the intestinal microbiota of infants in whom atopic eczema was or was not developing. Clin Exp Allergy. 2006;36(12):1602-1608.
    • (2006) Clin Exp Allergy , vol.36 , Issue.12 , pp. 1602-1608
    • Penders, J.1    Stobberingh, E.E.2    Thijs, C.3
  • 92
    • 80054851581 scopus 로고    scopus 로고
    • Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome
    • Saulnier DM, Riehle K, Mistretta TA, et al. Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome. Gastroenterology. 2011;141(5):1782-1791.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1782-1791
    • Saulnier, D.M.1    Riehle, K.2    Mistretta, T.A.3
  • 93
    • 80054857288 scopus 로고    scopus 로고
    • Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome
    • Rajilic-Stojanovic M, Biagi E, Heilig HG, et al. Global and deep molecular analysis of microbiota signatures in fecal samples from patients with irritable bowel syndrome. Gastroenterology. 2011;141(5):1792-1801.
    • (2011) Gastroenterology , vol.141 , Issue.5 , pp. 1792-1801
    • Rajilic-Stojanovic, M.1    Biagi, E.2    Heilig, H.G.3
  • 94
    • 80054939521 scopus 로고    scopus 로고
    • Irritable bowel syndrome, gut microbiota and probiotics
    • Lee BJ, Bak YT. Irritable bowel syndrome, gut microbiota and probiotics. J Neurogastroentero! Motil. 2011;17(3):252-266.
    • (2011) J Neurogastroentero! Motil. , vol.17 , Issue.3 , pp. 252-266
    • Lee, B.J.1    Bak, Y.T.2
  • 96
    • 33845874101 scopus 로고    scopus 로고
    • An obesity-associated gut microbiome with increased capacity for energy harvest
    • Tumbaugh PJ, Ley RE, Mahowald MA, Magrini V, Mardis ER, Gordon JI. An obesity-associated gut microbiome with increased capacity for energy harvest. Nature. 2006;444(7122):1027-1031.
    • (2006) Nature. , vol.444 , Issue.7122 , pp. 1027-1031
    • Tumbaugh, P.J.1    Ley, R.E.2    Mahowald, M.A.3    Magrini, V.4    Mardis, E.R.5    Gordon, J.I.6
  • 97
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • Tumbaugh PJ, Backhed F, Fulton L, Gordon JI. Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe. 2008;3(4) 213-223.
    • (2008) Cell Host Microbe. , vol.3 , Issue.4 , pp. 213-223
    • Tumbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 98
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: Human gut microbes associated with obesity
    • Ley RE, Tumbaugh PJ, Klein S, Gordon JI. Microbial ecology: human gut microbes associated with obesity. Nature. 2006;444(7122):1022-1023.
    • (2006) Nature. , vol.444 , Issue.7122 , pp. 1022-1023
    • Ley, R.E.1    Tumbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 99
    • 73949137604 scopus 로고    scopus 로고
    • Microbiota and SCFA in lean and overweight healthy subjects
    • Schwiertz A, Taras D, Schafer K, et al. Microbiota and SCFA in lean and overweight healthy subjects. Obesity (Silver Spring). 2010;18(1):190-195.
    • (2010) Obesity (Silver Spring) , vol.18 , Issue.1 , pp. 190-195
    • Schwiertz, A.1    Taras, D.2    Schafer, K.3
  • 100
    • 79953161490 scopus 로고    scopus 로고
    • Effects of the gut microbiota on obesity and glucose homeostasis
    • Greiner T, Backhed F. Effects of the gut microbiota on obesity and glucose homeostasis. Trends Endocrinol Metab. 2011;22(4):117-123.
    • (2011) Trends Endocrinol Metab. , vol.22 , Issue.4 , pp. 117-123
    • Greiner, T.1    Backhed, F.2
  • 101
    • 48249125862 scopus 로고    scopus 로고
    • Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice
    • Cani PD, Bibiloni R, Knauf C, et al. Changes in gut microbiota control metabolic endotoxemia-induced inflammation in high-fat diet-induced obesity and diabetes in mice. Diabetes. 2008;57(6):1470-1481.
    • (2008) Diabetes. , vol.57 , Issue.6 , pp. 1470-1481
    • Cani, P.D.1    Bibiloni, R.2    Knauf, C.3
  • 102
    • 78649908827 scopus 로고    scopus 로고
    • The role of the gut microbiota in nonalcoholic fatty liver disease
    • Abu-Shanab A, Quigley EM. The role of the gut microbiota in nonalcoholic fatty liver disease. Nat Rev Gastroenterol Hepatol. 2010;7(12):691-701.
    • (2010) Nat Rev Gastroenterol Hepatol. , vol.7 , Issue.12 , pp. 691-701
    • Abu-Shanab, A.1    Quigley, E.M.2
  • 103
    • 70349335851 scopus 로고    scopus 로고
    • Intestinal dysbiosis: A possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats
    • Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Alcohol Clin Exp Res. 2009;33(10):1836-1846.
    • (2009) Alcohol Clin Exp Res. , vol.33 , Issue.10 , pp. 1836-1846
    • Mutlu, E.1    Keshavarzian, A.2    Engen, P.3    Forsyth, C.B.4    Sikaroodi, M.5    Gillevet, P.6
  • 104
    • 54349095471 scopus 로고    scopus 로고
    • Microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: A tropical experience
    • Capoor MR, Nair D, Rajni, et al. Microflora of bile aspirates in patients with acute cholecystitis with or without cholelithiasis: a tropical experience. Braz J Infect Dis. 2008;12(3):222-225.
    • (2008) Braz J Infect Dis. , vol.12 , Issue.3 , pp. 222-225
    • Capoor, M.R.1    Nair, D.2    Rajni3
  • 106
    • 2342640188 scopus 로고    scopus 로고
    • Intestinal microflora in patients with liver cirrhosis
    • Zhao HY, Wang HJ, Lu Z, Xu SZ. Intestinal microflora in patients with liver cirrhosis. Chin J Dig Dis. 2004;5(2):64-67.
    • (2004) Chin J Dig Dis. , vol.5 , Issue.2 , pp. 64-67
    • Zhao, H.Y.1    Wang, H.J.2    Lu, Z.3    Xu, S.Z.4
  • 107
    • 2342580955 scopus 로고    scopus 로고
    • Synbiotic modulation of gut flora: Effect on minimal hepatic encephalopathy in patients with cirrhosis
    • Liu Q, Duan ZP, Ha DK, Bengmark S, Kurtovic J, Riordan SM. Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis. Hepatology. 2004;39(5):1441-1449.
    • (2004) Hepatology , vol.39 , Issue.5 , pp. 1441-1449
    • Liu, Q.1    Duan, Z.P.2    Ha, D.K.3    Bengmark, S.4    Kurtovic, J.5    Riordan, S.M.6
  • 108
    • 4043161248 scopus 로고    scopus 로고
    • Postnatal microbial colonization programs the hypothalamic-pituitary- adrenal system for stress response in mice
    • Sudo N, Chida Y, Aiba Y, et al. Postnatal microbial colonization programs the hypothalamic-pituitary-adrenal system for stress response in mice. J Physiol. 2004;558(pt 1) 263-275.
    • (2004) J Physiol. , vol.558 , Issue.PART 1 , pp. 263-275
    • Sudo, N.1    Chida, Y.2    Aiba, Y.3
  • 109
    • 79551694651 scopus 로고    scopus 로고
    • The microbiome-gut-brain axis: From bowel to behavior
    • Cryan JF, O'Mahony SM. The microbiome-gut-brain axis: from bowel to behavior. Neurogastroenterol Motil. 2011;23(3):187-192.
    • (2011) Neurogastroenterol Motil. , vol.23 , Issue.3 , pp. 187-192
    • Cryan, J.F.1    O'Mahony, S.M.2
  • 110
    • 79551713705 scopus 로고    scopus 로고
    • Reduced anxiety-like behavior and central neurochemical change in germ-free mice
    • e119
    • Neufeld KM, Kang N, Bienenstock J, Foster JA. Reduced anxiety-like behavior and central neurochemical change in germ-free mice. Neurogastroenterol Motil. 2011;23(3):255-264, e 119.
    • (2011) Neurogastroenterol Motil. , vol.23 , Issue.3 , pp. 255-264
    • Neufeld, K.M.1    Kang, N.2    Bienenstock, J.3    Foster, J.A.4


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