On the Origin of CRISPR-Cas Technology: From Prokaryotes to Mammals

Trends in Microbiology

Volumn 24, Issue 10, 2016, Pages 811-820

  Mojica, Francisco J M ^a   Montoliu, Lluis ^b,c  

^a UNIVERSITY OF ALICANTE   (Spain)

^b CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^c INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

gene disruption; gene replacement; gene therapy; genetic modification; genome editing nucleases; homologous recombination

Indexed keywords

CELLULAR APOPTOSIS SUSCEPTIBILITY PROTEIN;

ADAPTIVE IMMUNITY; BACTERIAL IMMUNITY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; DNA MODIFICATION; EMBRYONIC STEM CELL; GENETIC ENGINEERING; MAMMAL; NONHUMAN; PRIORITY JOURNAL; PROKARYOTE; REVIEW; ANIMAL; BACTERIUM; GENE EDITING; GENE THERAPY; GENETICS; GENOME; HOMOLOGOUS RECOMBINATION; HUMAN; PHYSIOLOGY; PROCEDURES; STREPTOCOCCUS PYOGENES;

ANIMALS; BACTERIA; CRISPR-CAS SYSTEMS; GENE EDITING; GENETIC ENGINEERING; GENETIC THERAPY; GENOME; HOMOLOGOUS RECOMBINATION; HUMANS; MAMMALS; STREPTOCOCCUS PYOGENES;

EID: 84990851668     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2016.06.005     Document Type: Review

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