Production of Human Albumin in Pigs Through CRISPR/Cas9-Mediated Knockin of Human cDNA into Swine Albumin Locus in the Zygotes

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Peng, Jin ^a   Wang, Yong ^b   Jiang, Junyi ^a   Zhou, Xiaoyang ^b   Song, Lei ^a   Wang, Lulu ^b   Ding, Chen ^a   Qin, Jun ^a   Liu, Liping ^e   Wang, Weihua ^f   Liu, Jianqiao ^f   Huang, Xingxu ^c   Wei, Hong ^b   Zhang, Pumin ^a,d  

^a BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

^c NANJING UNIVERSITY   (China)

^d BEIJING INSTITUTE OF LIFEOMICS   (China)

^e BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

^f GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; SERUM ALBUMIN;

ALLELE; ANIMAL; BIOSYNTHESIS; CRISPR CAS SYSTEM; GENE EXPRESSION; GENE LOCUS; GENE ORDER; GENE TARGETING; GENETICS; HUMAN; METABOLISM; PIG; ZYGOTE;

ALLELES; ANIMALS; CRISPR-CAS SYSTEMS; DNA, COMPLEMENTARY; GENE EXPRESSION; GENE KNOCK-IN TECHNIQUES; GENE ORDER; GENE TARGETING; GENETIC LOCI; HUMANS; SERUM ALBUMIN; SWINE; ZYGOTE;

EID: 84946925919     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep16705     Document Type: Article

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