The new CRISPR–Cas system: RNA-guided genome engineering to efficiently produce any desired genetic alteration in animals

Transgenic Research

Volumn 23, Issue 5, 2014, Pages 707-716

  Seruggia, Davide ^a,b   Montoliu, Lluis ^a,b  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

Author keywords

Animal models; CRISPR Cas; Engineered nucleases; Homologous recombination; Knock in; Knockout; Non homologous end joining; Transgenic

Indexed keywords

DEOXYRIBONUCLEASE;

ANIMAL; CRISPR CAS SYSTEM; DNA REPAIR; GENE TARGETING; GENETIC ENGINEERING; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; PRIMATE; PROCEDURES; SPECIES DIFFERENCE; ZEBRA FISH;

ANIMALS; CRISPR-CAS SYSTEMS; DEOXYRIBONUCLEASES; DNA REPAIR; GENE TARGETING; GENETIC ENGINEERING; MICE; PRIMATES; SPECIES SPECIFICITY; ZEBRAFISH;

EID: 84929133780     PISSN: 09628819     EISSN: 15739368     Source Type: Journal    
DOI: 10.1007/s11248-014-9823-y     Document Type: Review

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