-
1
-
-
62549141767
-
Economic burden of knee and hip osteoarthritis in Spain
-
Loza E, Lopez-Gomez JM, Abasolo L, et al. Economic burden of knee and hip osteoarthritis in Spain. Arthritis Rheum. 2009;61:158–165.
-
(2009)
Arthritis Rheum
, vol.61
, pp. 158-165
-
-
Loza, E.1
Lopez-Gomez, J.M.2
Abasolo, L.3
-
2
-
-
0027513751
-
Epidemiology of the rheumatic diseases
-
Spector TD. Epidemiology of the rheumatic diseases. Curr Opin Rheumatol. 1993;5:132–137.
-
(1993)
Curr Opin Rheumatol
, vol.5
, pp. 132-137
-
-
Spector, T.D.1
-
3
-
-
0027509678
-
Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1 (IX) collagen chains with a central deletion
-
Nakata K, Ono K, Miyazaki J, et al. Osteoarthritis associated with mild chondrodysplasia in transgenic mice expressing alpha 1 (IX) collagen chains with a central deletion. Proc Natl Acad Sci USA. 1993;90:2870–2874.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2870-2874
-
-
Nakata, K.1
Ono, K.2
Miyazaki, J.3
-
4
-
-
0035076295
-
Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis
-
Sandell LJ, Aigner T. Articular cartilage and changes in arthritis. An introduction: cell biology of osteoarthritis. Arthritis Res. 2001;3:107–113.
-
(2001)
Arthritis Res
, vol.3
, pp. 107-113
-
-
Sandell, L.J.1
Aigner, T.2
-
5
-
-
40949103073
-
Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes
-
Im HJ, Li X, Muddasani P, et al. Basic fibroblast growth factor accelerates matrix degradation via a neuro-endocrine pathway in human adult articular chondrocytes. J Cell Physiol. 2008;215:452–463.
-
(2008)
J Cell Physiol
, vol.215
, pp. 452-463
-
-
Im, H.J.1
Li, X.2
Muddasani, P.3
-
6
-
-
33745615815
-
Classification of osteoarthritis biomarkers: a proposed approach
-
Bauer DC, Hunter DJ, Abramson SB, et al. Classification of osteoarthritis biomarkers: a proposed approach. Osteoarthr Cartil. 2006;14:723–727.
-
(2006)
Osteoarthr Cartil
, vol.14
, pp. 723-727
-
-
Bauer, D.C.1
Hunter, D.J.2
Abramson, S.B.3
-
7
-
-
79955875528
-
OARSI-FDA initiative: defining the disease state of osteoarthritis
-
Lane NE, Brandt K, Hawker G, et al. OARSI-FDA initiative: defining the disease state of osteoarthritis. Osteoarthr Cartil. 2011;19:478–482.
-
(2011)
Osteoarthr Cartil
, vol.19
, pp. 478-482
-
-
Lane, N.E.1
Brandt, K.2
Hawker, G.3
-
8
-
-
0029902553
-
Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals
-
Reiter RJ. Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals. Eur J Endocrinol. 1996;134:412–420.
-
(1996)
Eur J Endocrinol
, vol.134
, pp. 412-420
-
-
Reiter, R.J.1
-
9
-
-
84946481377
-
Melatonin: an ancient molecule that makes oxygen metabolically tolerable
-
Manchester LC, Coto-Montes A, Boga JA, et al. Melatonin: an ancient molecule that makes oxygen metabolically tolerable. J Pineal Res. 2015;59:403–419.
-
(2015)
J Pineal Res
, vol.59
, pp. 403-419
-
-
Manchester, L.C.1
Coto-Montes, A.2
Boga, J.A.3
-
10
-
-
84986316068
-
Melatonin as an antioxidant: under promises but over delivers
-
in press.
-
Reiter RJ, Mayo JC, Tan DX, et al. Melatonin as an antioxidant: under promises but over delivers. J Pineal Res 2016;1–26; in press.
-
(2016)
J Pineal Res
, pp. 1-26
-
-
Reiter, R.J.1
Mayo, J.C.2
Tan, D.X.3
-
11
-
-
84943154978
-
Melatonin and vitamin E protects against sodium arsenite-induced skeletal malformations in rats
-
Khaksary Mahabady MK, Najafzadeh Varzi H, Ranjbar R, et al. Melatonin and vitamin E protects against sodium arsenite-induced skeletal malformations in rats. Am Eurasian J Toxicol Sci. 2011;3:184–189.
-
(2011)
Am Eurasian J Toxicol Sci
, vol.3
, pp. 184-189
-
-
Khaksary Mahabady, M.K.1
Najafzadeh Varzi, H.2
Ranjbar, R.3
-
12
-
-
79960380554
-
Melatonin as a natural ally against oxidative stress: a physiochemical examination
-
Galano A, Tan DX, Reiter RJ. Melatonin as a natural ally against oxidative stress: a physiochemical examination. J Pineal Res. 2011;51:1–16.
-
(2011)
J Pineal Res
, vol.51
, pp. 1-16
-
-
Galano, A.1
Tan, D.X.2
Reiter, R.J.3
-
13
-
-
84874949228
-
On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK
-
Galano A, Tan DX, Reiter RJ. On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK. J Pineal Res. 2013;54:245–257.
-
(2013)
J Pineal Res
, vol.54
, pp. 245-257
-
-
Galano, A.1
Tan, D.X.2
Reiter, R.J.3
-
14
-
-
12244304145
-
The chemistry of melatonin's interaction with reactive species
-
Allegra M, Reiter RJ, Tan DX, et al. The chemistry of melatonin's interaction with reactive species. J Pineal Res. 2003;34:1–10.
-
(2003)
J Pineal Res
, vol.34
, pp. 1-10
-
-
Allegra, M.1
Reiter, R.J.2
Tan, D.X.3
-
15
-
-
1642562820
-
Regulation of antioxidant enzymes: a significant role for melatonin
-
Rodriguez C, Mayo JC, Sainz RM, et al. Regulation of antioxidant enzymes: a significant role for melatonin. J Pineal Res. 2004;36:1–9.
-
(2004)
J Pineal Res
, vol.36
, pp. 1-9
-
-
Rodriguez, C.1
Mayo, J.C.2
Sainz, R.M.3
-
16
-
-
84959326217
-
Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney
-
Mehrzadi S, Kamrava SK, Dormanesh B, et al. Melatonin synergistically enhances protective effect of atorvastatin against gentamicin-induced nephrotoxicity in rat kidney. Can J Physiol Pharmacol. 2016;94:265–271.
-
(2016)
Can J Physiol Pharmacol
, vol.94
, pp. 265-271
-
-
Mehrzadi, S.1
Kamrava, S.K.2
Dormanesh, B.3
-
17
-
-
84989221417
-
Comparison of the protective effects of melatonin and silymarin against gentamicin-induced nephrotoxicity in rats
-
in press.
-
Ghaznavi H, Mehrzadi S, Dormanesh B, et al. Comparison of the protective effects of melatonin and silymarin against gentamicin-induced nephrotoxicity in rats. J Evid Based Complementary Altern Med. 2015;1–7; in press.
-
(2015)
J Evid Based Complementary Altern Med
, pp. 1-7
-
-
Ghaznavi, H.1
Mehrzadi, S.2
Dormanesh, B.3
-
19
-
-
84918772976
-
Melatonin enhances the human mesenchymal stem cells mobility via melatonin receptor 2 coupling with Gαq in skin wound healing
-
Lee SJ, Jung YH, Oh SY, et al. Melatonin enhances the human mesenchymal stem cells mobility via melatonin receptor 2 coupling with Gαq in skin wound healing. J Pineal Res. 2014;57:393–407.
-
(2014)
J Pineal Res
, vol.57
, pp. 393-407
-
-
Lee, S.J.1
Jung, Y.H.2
Oh, S.Y.3
-
20
-
-
84904470767
-
Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo-controlled, clinical trial
-
Gögenur I, Kücükakin B, Panduro Jensen L, et al. Melatonin reduces cardiac morbidity and markers of myocardial ischemia after elective abdominal aortic aneurism repair: a randomized, placebo-controlled, clinical trial. J Pineal Res. 2014;57:10–15.
-
(2014)
J Pineal Res
, vol.57
, pp. 10-15
-
-
Gögenur, I.1
Kücükakin, B.2
Panduro Jensen, L.3
-
21
-
-
84926509470
-
Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear impact mediated by CaMk11 inactivation
-
Wei JY, Li WM, Zhou LL, et al. Melatonin induces apoptosis of colorectal cancer cells through HDAC4 nuclear impact mediated by CaMk11 inactivation. J Pineal Res. 2015;58:429–438.
-
(2015)
J Pineal Res
, vol.58
, pp. 429-438
-
-
Wei, J.Y.1
Li, W.M.2
Zhou, L.L.3
-
22
-
-
84955212354
-
Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression
-
Borin TF, Arbab AS, Gelaleti GB, et al. Melatonin decreases breast cancer metastasis by modulating Rho-associated kinase protein-1 expression. J Pineal Res. 2016;60:3–15.
-
(2016)
J Pineal Res
, vol.60
, pp. 3-15
-
-
Borin, T.F.1
Arbab, A.S.2
Gelaleti, G.B.3
-
23
-
-
0025753752
-
Oxygen radicals, inflammation, and arthritis: pathophysiological considerations and implications for treatment
-
Greenwald RA. Oxygen radicals, inflammation, and arthritis: pathophysiological considerations and implications for treatment. Semin Arthritis Rheum. 1991;20:219–240.
-
(1991)
Semin Arthritis Rheum
, vol.20
, pp. 219-240
-
-
Greenwald, R.A.1
-
24
-
-
0141504018
-
The role of reactive oxygen species in homeostasis and degradation of cartilage
-
Henrotin YE, Bruckner P, Pujol JP. The role of reactive oxygen species in homeostasis and degradation of cartilage. Osteoarthr Cartil. 2003;11:747–755.
-
(2003)
Osteoarthr Cartil
, vol.11
, pp. 747-755
-
-
Henrotin, Y.E.1
Bruckner, P.2
Pujol, J.P.3
-
25
-
-
4344688108
-
Post-traumatic osteoarthritis: the role of accelerated chondrocyte senescence
-
Martin JA, Brown T, Heiner A, et al. Post-traumatic osteoarthritis: the role of accelerated chondrocyte senescence. Biorheology. 2004;41:479–492.
-
(2004)
Biorheology
, vol.41
, pp. 479-492
-
-
Martin, J.A.1
Brown, T.2
Heiner, A.3
-
26
-
-
5444264829
-
Chondrocyte senescence, joint loading and osteoarthritis
-
Martin JA, Brown TD, Heiner AD, et al. Chondrocyte senescence, joint loading and osteoarthritis. Clin Orthop Relat Res. 2004;427:S96–S103.
-
(2004)
Clin Orthop Relat Res
, vol.427
, pp. S96-S103
-
-
Martin, J.A.1
Brown, T.D.2
Heiner, A.D.3
-
27
-
-
0034267021
-
Evidence supporting an increased presence of reactive oxygen species in the diseased equine joint
-
Dimock AN, Siciliano PD, McIlwraith CW. Evidence supporting an increased presence of reactive oxygen species in the diseased equine joint. Equine Vet J. 2000;32:439–443.
-
(2000)
Equine Vet J
, vol.32
, pp. 439-443
-
-
Dimock, A.N.1
Siciliano, P.D.2
McIlwraith, C.W.3
-
28
-
-
5444259084
-
The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide
-
Goldring MB, Berenbaum F. The regulation of chondrocyte function by proinflammatory mediators: prostaglandins and nitric oxide. Clin Orthop Relat Res. 2004;427:S37–S46.
-
(2004)
Clin Orthop Relat Res
, vol.427
, pp. S37-S46
-
-
Goldring, M.B.1
Berenbaum, F.2
-
29
-
-
0036793531
-
Oxygen radicals and nitric oxide levels in chondral or meniscal lesions or both
-
Haklar U, Yüksel M, Velioglu A, et al. Oxygen radicals and nitric oxide levels in chondral or meniscal lesions or both. Clin Orthop Relat Res. 2002;403:135–142.
-
(2002)
Clin Orthop Relat Res
, vol.403
, pp. 135-142
-
-
Haklar, U.1
Yüksel, M.2
Velioglu, A.3
-
30
-
-
34249688522
-
Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cδ pathways in human adult articular chondrocytes
-
Im HJ, Muddasani P, Natarajan V, et al. Basic fibroblast growth factor stimulates matrix metalloproteinase-13 via the molecular cross-talk between the mitogen-activated protein kinases and protein kinase Cδ pathways in human adult articular chondrocytes. J Biol Chem. 2007;282:11110–11121.
-
(2007)
J Biol Chem
, vol.282
, pp. 11110-11121
-
-
Im, H.J.1
Muddasani, P.2
Natarajan, V.3
-
31
-
-
0034441693
-
Reactive oxygen species participation in experimentally induced arthritis of the temporomandibular joint in rats
-
Kawai Y, Kubota E, Okabe E. Reactive oxygen species participation in experimentally induced arthritis of the temporomandibular joint in rats. J Dent Res. 2000;79:1489–1495.
-
(2000)
J Dent Res
, vol.79
, pp. 1489-1495
-
-
Kawai, Y.1
Kubota, E.2
Okabe, E.3
-
32
-
-
30544442656
-
Lipid peroxidation and antioxidant enzymes in synovial fluid of patients with primary and secondary osteoarthritis of the knee joint
-
Ostalowska A, Birkner E, Wiecha M, et al. Lipid peroxidation and antioxidant enzymes in synovial fluid of patients with primary and secondary osteoarthritis of the knee joint. Osteoarthr Cartil. 2006;14:139–145.
-
(2006)
Osteoarthr Cartil
, vol.14
, pp. 139-145
-
-
Ostalowska, A.1
Birkner, E.2
Wiecha, M.3
-
33
-
-
1842781743
-
Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence
-
Martin JA, Klingelhutz AJ, Moussavi-Harami F, et al. Effects of oxidative damage and telomerase activity on human articular cartilage chondrocyte senescence. J Gerontol A Biol Sci Med Sci. 2004;59:324–336.
-
(2004)
J Gerontol A Biol Sci Med Sci
, vol.59
, pp. 324-336
-
-
Martin, J.A.1
Klingelhutz, A.J.2
Moussavi-Harami, F.3
-
34
-
-
0037442224
-
Microsatellite instability and suppressed DNA repair enzyme expression in rheumatoid arthritis
-
Lee SH, Chang DK, Goel A, et al. Microsatellite instability and suppressed DNA repair enzyme expression in rheumatoid arthritis. J Immunol. 2003;170:2214–2220.
-
(2003)
J Immunol
, vol.170
, pp. 2214-2220
-
-
Lee, S.H.1
Chang, D.K.2
Goel, A.3
-
35
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens JF. Mitochondrial formation of reactive oxygen species. J Physiol. 2003;552:335–344.
-
(2003)
J Physiol
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
36
-
-
84930468564
-
Neuro-protective effects of cerium and yttrium oxide nanoparticles on high glucose-induced oxidative stress and apoptosis in undifferentiated PC12 cells
-
Ghaznavi H, Najafi R, Mehrzadi S, et al. Neuro-protective effects of cerium and yttrium oxide nanoparticles on high glucose-induced oxidative stress and apoptosis in undifferentiated PC12 cells. Neurol Res. 2015;37:624–632.
-
(2015)
Neurol Res
, vol.37
, pp. 624-632
-
-
Ghaznavi, H.1
Najafi, R.2
Mehrzadi, S.3
-
37
-
-
25144461499
-
Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes
-
Da Sylva TR, Connor A, Mburu Y, et al. Somatic mutations in the mitochondria of rheumatoid arthritis synoviocytes. Arthritis Res Ther. 2005;7:R844–R851.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. R844-R851
-
-
Da Sylva, T.R.1
Connor, A.2
Mburu, Y.3
-
38
-
-
57349106464
-
Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes
-
Grishko VI, Ho R, Wilson GL, et al. Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes. Osteoarthr Cartil. 2009;17:107–113.
-
(2009)
Osteoarthr Cartil
, vol.17
, pp. 107-113
-
-
Grishko, V.I.1
Ho, R.2
Wilson, G.L.3
-
39
-
-
25144436460
-
Somatic mutations in mitochondria: the chicken or the egg?
-
Ospelt C, Gay S. Somatic mutations in mitochondria: the chicken or the egg? Arthritis Res Ther. 2005;7:179.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 179
-
-
Ospelt, C.1
Gay, S.2
-
41
-
-
1842683010
-
Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs
-
Johnson K, Svensson CI, Etten DV, et al. Mediation of spontaneous knee osteoarthritis by progressive chondrocyte ATP depletion in Hartley guinea pigs. Arthritis Rheum. 2004;50:1216–1225.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 1216-1225
-
-
Johnson, K.1
Svensson, C.I.2
Etten, D.V.3
-
42
-
-
77956010838
-
Mitochondrial function is altered in articular chondrocytes of an endemic osteoarthritis, Kashin-Beck disease
-
Liu JT, Guo X, Ma WJ, et al. Mitochondrial function is altered in articular chondrocytes of an endemic osteoarthritis, Kashin-Beck disease. Osteoarthr Cartil. 2010;18:1218–1226.
-
(2010)
Osteoarthr Cartil
, vol.18
, pp. 1218-1226
-
-
Liu, J.T.1
Guo, X.2
Ma, W.J.3
-
43
-
-
0037334593
-
Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes
-
Maneiro E, Martín MA, de Andres MC, et al. Mitochondrial respiratory activity is altered in osteoarthritic human articular chondrocytes. Arthritis Rheum. 2003;48:700–708.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 700-708
-
-
Maneiro, E.1
Martín, M.A.2
de Andres, M.C.3
-
44
-
-
49449104156
-
The complex pathology of osteoarthritis: even mitochondria are involved
-
Roach HI. The complex pathology of osteoarthritis: even mitochondria are involved. Arthritis Rheum. 2008;58:2217–2218.
-
(2008)
Arthritis Rheum
, vol.58
, pp. 2217-2218
-
-
Roach, H.I.1
-
45
-
-
0036210361
-
Invited review: the mitochondrion in osteoarthritis
-
Terkeltaub R, Johnson K, Murphy A, et al. Invited review: the mitochondrion in osteoarthritis. Mitochondrion. 2002;1:301–319.
-
(2002)
Mitochondrion
, vol.1
, pp. 301-319
-
-
Terkeltaub, R.1
Johnson, K.2
Murphy, A.3
-
46
-
-
0034805917
-
Epidemiology of risk factors for osteoarthritis: systemic factors
-
Sowers M. Epidemiology of risk factors for osteoarthritis: systemic factors. Curr Opin Rheumatol. 2001;13:447–451.
-
(2001)
Curr Opin Rheumatol
, vol.13
, pp. 447-451
-
-
Sowers, M.1
-
47
-
-
0025814980
-
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
-
Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. Free Radic Biol Med. 1991;11:81–128.
-
(1991)
Free Radic Biol Med
, vol.11
, pp. 81-128
-
-
Esterbauer, H.1
Schaur, R.J.2
Zollner, H.3
-
48
-
-
33646932475
-
The generation and actions of isoprostanes
-
Roberts LJ, Morrow JD. The generation and actions of isoprostanes. Biochim Biophys Acta. 1997;1345:121–135.
-
(1997)
Biochim Biophys Acta
, vol.1345
, pp. 121-135
-
-
Roberts, L.J.1
Morrow, J.D.2
-
49
-
-
0035011337
-
Raised levels of F2-isoprostanes and prostaglandin F2α in different rheumatic diseases
-
Basu S, Whiteman M, Mattey DL, et al. Raised levels of F2-isoprostanes and prostaglandin F2α in different rheumatic diseases. Ann Rheum Dis. 2001;60:627–631.
-
(2001)
Ann Rheum Dis
, vol.60
, pp. 627-631
-
-
Basu, S.1
Whiteman, M.2
Mattey, D.L.3
-
50
-
-
0025907055
-
The association of lipid abnormalities with tissue pathology in human osteoarthritic articular cartilage
-
Lippiello L, Walsh T, Fienhold M. The association of lipid abnormalities with tissue pathology in human osteoarthritic articular cartilage. Metabolism. 1991;40:571–576.
-
(1991)
Metabolism
, vol.40
, pp. 571-576
-
-
Lippiello, L.1
Walsh, T.2
Fienhold, M.3
-
51
-
-
0033065891
-
Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants
-
Tiku ML, Gupta S, Deshmukh DR. Aggrecan degradation in chondrocytes is mediated by reactive oxygen species and protected by antioxidants. Free Radic Res. 1999;30:395–405.
-
(1999)
Free Radic Res
, vol.30
, pp. 395-405
-
-
Tiku, M.L.1
Gupta, S.2
Deshmukh, D.R.3
-
52
-
-
0031794616
-
Hydroxyl radical formation in chondrocytes and cartilage as detected by electron paramagnetic resonance spectroscopy using spin trapping reagents
-
Tiku ML, Yan YP, Chen KY. Hydroxyl radical formation in chondrocytes and cartilage as detected by electron paramagnetic resonance spectroscopy using spin trapping reagents. Free Radic Res. 1998;29:177–187.
-
(1998)
Free Radic Res
, vol.29
, pp. 177-187
-
-
Tiku, M.L.1
Yan, Y.P.2
Chen, K.Y.3
-
53
-
-
0038147318
-
Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs
-
Martel-Pelletier J, Lajeunesse D, Reboul P, et al. Therapeutic role of dual inhibitors of 5-LOX and COX, selective and non-selective non-steroidal anti-inflammatory drugs. Ann Rheum Dis. 2003;62:501–509.
-
(2003)
Ann Rheum Dis
, vol.62
, pp. 501-509
-
-
Martel-Pelletier, J.1
Lajeunesse, D.2
Reboul, P.3
-
54
-
-
0035976575
-
Prostaglandins and leukotrienes: advances in eicosanoid biology
-
Funk CD. Prostaglandins and leukotrienes: advances in eicosanoid biology. Science. 2001;294:1871–1875.
-
(2001)
Science
, vol.294
, pp. 1871-1875
-
-
Funk, C.D.1
-
55
-
-
0020842196
-
Effect of prostaglandin E2 on adult pig articular cartilage slices in culture
-
Fulkerson JP, Damiano P. Effect of prostaglandin E2 on adult pig articular cartilage slices in culture. Clin Orthop Relat Res. 1983;179:266–269.
-
(1983)
Clin Orthop Relat Res
, vol.179
, pp. 266-269
-
-
Fulkerson, J.P.1
Damiano, P.2
-
56
-
-
0036064137
-
Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants
-
Hardy MM, Seibert K, Manning PT, et al. Cyclooxygenase 2-dependent prostaglandin E2 modulates cartilage proteoglycan degradation in human osteoarthritis explants. Arthritis Rheum. 2002;46:1789–1803.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 1789-1803
-
-
Hardy, M.M.1
Seibert, K.2
Manning, P.T.3
-
57
-
-
0027419081
-
Induction of macrophage metalloproteinases by extracellular matrix. Evidence for enzyme-and substrate-specific responses involving prostaglandin-dependent mechanisms
-
Shapiro SD, Kobayashi DK, Pentland AP, et al. Induction of macrophage metalloproteinases by extracellular matrix. Evidence for enzyme-and substrate-specific responses involving prostaglandin-dependent mechanisms. J Biol Chem. 1993;268:8170–8175.
-
(1993)
J Biol Chem
, vol.268
, pp. 8170-8175
-
-
Shapiro, S.D.1
Kobayashi, D.K.2
Pentland, A.P.3
-
59
-
-
0029801511
-
Effects of indomethacin on the production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by human articular chondrocytes
-
Yamada H, Kikuchi T, Nemoto O, et al. Effects of indomethacin on the production of matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by human articular chondrocytes. J Rheumatol. 1996;23:1739–1743.
-
(1996)
J Rheumatol
, vol.23
, pp. 1739-1743
-
-
Yamada, H.1
Kikuchi, T.2
Nemoto, O.3
-
60
-
-
0033990344
-
Cell type-specific role for reactive oxygen species in nuclear factor-kappaB activation by interleukin-1
-
Bonizzi G, Piette J, Merville MP, et al. Cell type-specific role for reactive oxygen species in nuclear factor-kappaB activation by interleukin-1. Biochem Pharmacol. 2000;59:7–11.
-
(2000)
Biochem Pharmacol
, vol.59
, pp. 7-11
-
-
Bonizzi, G.1
Piette, J.2
Merville, M.P.3
-
62
-
-
0034644753
-
Tumor necrosis factor-α generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade
-
Woo CH, Eom YW, Yoo MH, et al. Tumor necrosis factor-α generates reactive oxygen species via a cytosolic phospholipase A2-linked cascade. J Biol Chem. 2000;275:32357–32362.
-
(2000)
J Biol Chem
, vol.275
, pp. 32357-32362
-
-
Woo, C.H.1
Eom, Y.W.2
Yoo, M.H.3
-
63
-
-
0034876562
-
Leukotriene B4 promotes reactive oxidant generation and leukocyte adherence during acute hypoxia
-
Steiner DR, Gonzalez NC, Wood JG. Leukotriene B4 promotes reactive oxidant generation and leukocyte adherence during acute hypoxia. J Appl Physiol. 2001;91:1160–1167.
-
(2001)
J Appl Physiol
, vol.91
, pp. 1160-1167
-
-
Steiner, D.R.1
Gonzalez, N.C.2
Wood, J.G.3
-
64
-
-
0033775218
-
Osteoarthritis: new insights. Part 1: the disease and its risk factors
-
Felson DT, Lawrence RC, Dieppe PA, et al. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med. 2000;133:635–646.
-
(2000)
Ann Intern Med
, vol.133
, pp. 635-646
-
-
Felson, D.T.1
Lawrence, R.C.2
Dieppe, P.A.3
-
65
-
-
0034619417
-
Osteoarthritis: new insights. Part 2: treatment approaches
-
Felson DT, Lawrence RC, Hochberg MC, et al. Osteoarthritis: new insights. Part 2: treatment approaches. Ann Intern Med. 2000;133:726–737.
-
(2000)
Ann Intern Med
, vol.133
, pp. 726-737
-
-
Felson, D.T.1
Lawrence, R.C.2
Hochberg, M.C.3
-
66
-
-
0030612396
-
Detection of superoxide and NADPH oxidase in porcine articular chondrocytes
-
Hiran TS, Moulton PJ, Hancock JT. Detection of superoxide and NADPH oxidase in porcine articular chondrocytes. Free Radic Biol Med. 1997;23:736–743.
-
(1997)
Free Radic Biol Med
, vol.23
, pp. 736-743
-
-
Hiran, T.S.1
Moulton, P.J.2
Hancock, J.T.3
-
67
-
-
0026474322
-
Release of oxygen radicals by articular chondrocytes: a study of luminol-dependent chemiluminescence and hydrogen peroxide secretion
-
Rathakrishnan C, Tiku K, Raghavan A, et al. Release of oxygen radicals by articular chondrocytes: a study of luminol-dependent chemiluminescence and hydrogen peroxide secretion. J Bone Miner Res. 1992;7:1139–1148.
-
(1992)
J Bone Miner Res
, vol.7
, pp. 1139-1148
-
-
Rathakrishnan, C.1
Tiku, K.2
Raghavan, A.3
-
68
-
-
0029020218
-
Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes
-
Lo YY, Cruz TF. Involvement of reactive oxygen species in cytokine and growth factor induction of c-fos expression in chondrocytes. J Biol Chem. 1995;270:11727–11730.
-
(1995)
J Biol Chem
, vol.270
, pp. 11727-11730
-
-
Lo, Y.Y.1
Cruz, T.F.2
-
69
-
-
0347088927
-
Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression
-
Kurz B, Lemke A, Kehn M, et al. Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression. Arthritis Rheum. 2004;50:123–130.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 123-130
-
-
Kurz, B.1
Lemke, A.2
Kehn, M.3
-
70
-
-
0025369970
-
The measurement and mechanism of lipid peroxidation in biological systems
-
Gutteridge JM, Halliwell B. The measurement and mechanism of lipid peroxidation in biological systems. Trends Biochem Sci. 1990;15:129–135.
-
(1990)
Trends Biochem Sci
, vol.15
, pp. 129-135
-
-
Gutteridge, J.M.1
Halliwell, B.2
-
71
-
-
0024996225
-
Production of hydrogen peroxide by rabbit articular chondrocytes. Enhancement by cytokines
-
Tiku ML, Liesch JB, Robertson FM. Production of hydrogen peroxide by rabbit articular chondrocytes. Enhancement by cytokines. J Immunol. 1990;145:690–696.
-
(1990)
J Immunol
, vol.145
, pp. 690-696
-
-
Tiku, M.L.1
Liesch, J.B.2
Robertson, F.M.3
-
72
-
-
0021968261
-
Inhibition of proteoglycan synthesis by hydrogen peroxide in cultured bovine articular cartilage
-
Bates EJ, Johnson CC, Lowther DA. Inhibition of proteoglycan synthesis by hydrogen peroxide in cultured bovine articular cartilage. Biochim Biophys Acta. 1985;838:221–228.
-
(1985)
Biochim Biophys Acta
, vol.838
, pp. 221-228
-
-
Bates, E.J.1
Johnson, C.C.2
Lowther, D.A.3
-
73
-
-
0035136052
-
Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase
-
Asada S, Fukuda K, Nishisaka F, et al. Hydrogen peroxide induces apoptosis of chondrocytes; involvement of calcium ion and extracellular signal-regulated protein kinase. Inflamm Res. 2001;50:19–23.
-
(2001)
Inflamm Res
, vol.50
, pp. 19-23
-
-
Asada, S.1
Fukuda, K.2
Nishisaka, F.3
-
74
-
-
0034733622
-
Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation possible role in cartilage aging and the pathogenesis of osteoarthritis
-
Tiku ML, Shah R, Allison GT. Evidence linking chondrocyte lipid peroxidation to cartilage matrix protein degradation possible role in cartilage aging and the pathogenesis of osteoarthritis. J Biol Chem. 2000;275:20069–20076.
-
(2000)
J Biol Chem
, vol.275
, pp. 20069-20076
-
-
Tiku, M.L.1
Shah, R.2
Allison, G.T.3
-
75
-
-
33947730699
-
The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation
-
Jacques C, Gosset M, Berenbaum F, et al. The role of IL-1 and IL-1Ra in joint inflammation and cartilage degradation. Vitam Horm. 2006;74:371–403.
-
(2006)
Vitam Horm
, vol.74
, pp. 371-403
-
-
Jacques, C.1
Gosset, M.2
Berenbaum, F.3
-
76
-
-
0031833414
-
The role of nitric oxide in articular cartilage breakdown in osteoarthritis
-
Amin AR, Abramson SB. The role of nitric oxide in articular cartilage breakdown in osteoarthritis. Curr Opin Rheumatol. 1998;10:263–268.
-
(1998)
Curr Opin Rheumatol
, vol.10
, pp. 263-268
-
-
Amin, A.R.1
Abramson, S.B.2
-
77
-
-
51549116292
-
Osteoarthritis and nitric oxide
-
Abramson SB. Osteoarthritis and nitric oxide. Osteoarthr Cartil. 2008;16:S15–S20.
-
(2008)
Osteoarthr Cartil
, vol.16
, pp. S15-S20
-
-
Abramson, S.B.1
-
78
-
-
0029986420
-
The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation
-
Pelletier JP, Mineau F, Ranger P, et al. The increased synthesis of inducible nitric oxide inhibits IL-1ra synthesis by human articular chondrocytes: possible role in osteoarthritic cartilage degradation. Osteoarthr Cartil. 1996;4:77–84.
-
(1996)
Osteoarthr Cartil
, vol.4
, pp. 77-84
-
-
Pelletier, J.P.1
Mineau, F.2
Ranger, P.3
-
79
-
-
0028830920
-
Chondrocyte apoptosis induced by nitric oxide
-
Blanco FJ, Ochs RL, Schwarz H, et al. Chondrocyte apoptosis induced by nitric oxide. Am J Pathol. 1995;146:75.
-
(1995)
Am J Pathol
, vol.146
, pp. 75
-
-
Blanco, F.J.1
Ochs, R.L.2
Schwarz, H.3
-
81
-
-
0031939315
-
Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes
-
Sasaki K, Hattori T, Fujisawa T, et al. Nitric oxide mediates interleukin-1-induced gene expression of matrix metalloproteinases and basic fibroblast growth factor in cultured rabbit articular chondrocytes. J Biochem. 1998;123:431–439.
-
(1998)
J Biochem
, vol.123
, pp. 431-439
-
-
Sasaki, K.1
Hattori, T.2
Fujisawa, T.3
-
82
-
-
73849152727
-
N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis
-
Nakagawa S, Arai Y, Mazda O, et al. N-acetylcysteine prevents nitric oxide-induced chondrocyte apoptosis and cartilage degeneration in an experimental model of osteoarthritis. J Orthop Res. 2010;28:156–163.
-
(2010)
J Orthop Res
, vol.28
, pp. 156-163
-
-
Nakagawa, S.1
Arai, Y.2
Mazda, O.3
-
83
-
-
80052209352
-
Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy
-
Chevalier X, Conrozier T, Richette P. Desperately looking for the right target in osteoarthritis: the anti-IL-1 strategy. Arthritis Res Ther. 2011;13:124.
-
(2011)
Arthritis Res Ther
, vol.13
, pp. 124
-
-
Chevalier, X.1
Conrozier, T.2
Richette, P.3
-
84
-
-
33745044261
-
Cytokines, tumor necrosis factor-α and interleukin-1β, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes
-
López-Armada MJ, Caramés B, Lires-Deán M, et al. Cytokines, tumor necrosis factor-α and interleukin-1β, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes. Osteoarthr Cartil. 2006;14:660–669.
-
(2006)
Osteoarthr Cartil
, vol.14
, pp. 660-669
-
-
López-Armada, M.J.1
Caramés, B.2
Lires-Deán, M.3
-
85
-
-
0035472206
-
Annotating genes with potential roles in the immune system: six new members of the IL-1 family
-
Dunn E, Sims JE, Nicklin MJ, et al. Annotating genes with potential roles in the immune system: six new members of the IL-1 family. Trends Immunol. 2001;22:533–536.
-
(2001)
Trends Immunol
, vol.22
, pp. 533-536
-
-
Dunn, E.1
Sims, J.E.2
Nicklin, M.J.3
-
86
-
-
34247630598
-
Cloning IL-1 and the birth of a new era in cytokine biology
-
Pizarro TT, Cominelli F. Cloning IL-1 and the birth of a new era in cytokine biology. J Immunol. 2007;178:5411–5412.
-
(2007)
J Immunol
, vol.178
, pp. 5411-5412
-
-
Pizarro, T.T.1
Cominelli, F.2
-
87
-
-
0035471572
-
A new nomenclature for IL-1-family genes
-
Sims JE, Pan Y, Smith DE, et al. A new nomenclature for IL-1-family genes. Trends Immunol. 2001;22:536.
-
(2001)
Trends Immunol
, vol.22
, pp. 536
-
-
Sims, J.E.1
Pan, Y.2
Smith, D.E.3
-
88
-
-
0031831906
-
Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist
-
Dinarello CA. Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonist. Int Rev Immunol. 1998;16:457–499.
-
(1998)
Int Rev Immunol
, vol.16
, pp. 457-499
-
-
Dinarello, C.A.1
-
89
-
-
0036234745
-
Production of interleukin-1 receptor antagonist by human articular chondrocytes
-
Palmer G, Guerne PA, Mezin F, et al. Production of interleukin-1 receptor antagonist by human articular chondrocytes. Arthritis Res. 2002;4:226–231.
-
(2002)
Arthritis Res
, vol.4
, pp. 226-231
-
-
Palmer, G.1
Guerne, P.A.2
Mezin, F.3
-
90
-
-
0028207511
-
Production of interleukin-1 receptor antagonist, inflammatory chemotactic proteins, and prostaglandin E by rheumatoid and osteoarthritic synoviocytes–regulation by IFN-gamma and IL-4
-
Seitz M, Loetscher P, Dewald B, et al. Production of interleukin-1 receptor antagonist, inflammatory chemotactic proteins, and prostaglandin E by rheumatoid and osteoarthritic synoviocytes–regulation by IFN-gamma and IL-4. J Immunol. 1994;152:2060–2065.
-
(1994)
J Immunol
, vol.152
, pp. 2060-2065
-
-
Seitz, M.1
Loetscher, P.2
Dewald, B.3
-
91
-
-
0031047265
-
Synovial membrane inflammation and cytokine production in patients with early osteoarthritis
-
Smith MD, Triantafillou S, Parker A, et al. Synovial membrane inflammation and cytokine production in patients with early osteoarthritis. J Rheumatol. 1997;24:365–371.
-
(1997)
J Rheumatol
, vol.24
, pp. 365-371
-
-
Smith, M.D.1
Triantafillou, S.2
Parker, A.3
-
92
-
-
0031031240
-
Interleukin 1β and stromelysin (MMP3) activity of synovial fluid as possible markers of osteoarthritis in the temporomandibular joint
-
Kubota E, Imamura H, Kubota T, et al. Interleukin 1β and stromelysin (MMP3) activity of synovial fluid as possible markers of osteoarthritis in the temporomandibular joint. J Oral Maxillofac Surg. 1997;55:20–27.
-
(1997)
J Oral Maxillofac Surg
, vol.55
, pp. 20-27
-
-
Kubota, E.1
Imamura, H.2
Kubota, T.3
-
93
-
-
0036745073
-
Detection of nitrotyrosine in aging and osteoarthritic cartilage: correlation of oxidative damage with the presence of interleukin-1β and with chondrocyte resistance to insulin-like growth factor 1
-
Loeser RF, Carlson CS, Del Carlo M, et al. Detection of nitrotyrosine in aging and osteoarthritic cartilage: correlation of oxidative damage with the presence of interleukin-1β and with chondrocyte resistance to insulin-like growth factor 1. Arthritis Rheum. 2002;46:2349–2357.
-
(2002)
Arthritis Rheum
, vol.46
, pp. 2349-2357
-
-
Loeser, R.F.1
Carlson, C.S.2
Del Carlo, M.3
-
94
-
-
0028950175
-
Synthesis of metalloproteases and interleukin 6 (IL-6) in human osteoarthritic synovial membrane is an IL-1 mediated process
-
Pelletier JP, McCollum R, Cloutier JM, et al. Synthesis of metalloproteases and interleukin 6 (IL-6) in human osteoarthritic synovial membrane is an IL-1 mediated process. J Rheumatol Suppl. 1995;43:109–114.
-
(1995)
J Rheumatol Suppl
, vol.43
, pp. 109-114
-
-
Pelletier, J.P.1
McCollum, R.2
Cloutier, J.M.3
-
96
-
-
77950627242
-
IL-1 pathways in inflammation and human diseases
-
Gabay C, Lamacchia C, Palmer G. IL-1 pathways in inflammation and human diseases. Nat Rev Rheumatol. 2010;6:232–241.
-
(2010)
Nat Rev Rheumatol
, vol.6
, pp. 232-241
-
-
Gabay, C.1
Lamacchia, C.2
Palmer, G.3
-
97
-
-
0001031383
-
Structure-function relationship in the IL-1 family
-
Boraschi D, Bossu P, Macchia G, et al. Structure-function relationship in the IL-1 family. Front Biosci. 1996;1:d270–d308.
-
(1996)
Front Biosci
, vol.1
, pp. d270-d308
-
-
Boraschi, D.1
Bossu, P.2
Macchia, G.3
-
98
-
-
0034092320
-
Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis
-
Shlopov BV, Gumanovskaya ML, Hasty KA. Autocrine regulation of collagenase 3 (matrix metalloproteinase 13) during osteoarthritis. Arthritis Rheum. 2000;43:195–205.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 195-205
-
-
Shlopov, B.V.1
Gumanovskaya, M.L.2
Hasty, K.A.3
-
99
-
-
0027333425
-
Tumor necrosis factor, other cytokines and disease
-
Tracey KJ, Cerami A. Tumor necrosis factor, other cytokines and disease. Annu Rev Cell Biol. 1993;9:317–343.
-
(1993)
Annu Rev Cell Biol
, vol.9
, pp. 317-343
-
-
Tracey, K.J.1
Cerami, A.2
-
100
-
-
0035444539
-
Signal transduction by tumor necrosis factor and its relatives
-
Baud V, Karin M. Signal transduction by tumor necrosis factor and its relatives. Trends Cell Biol. 2001;11:372–377.
-
(2001)
Trends Cell Biol
, vol.11
, pp. 372-377
-
-
Baud, V.1
Karin, M.2
-
102
-
-
85047692516
-
Signalling pathways of the TNF superfamily: a double-edged sword
-
Aggarwal BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol. 2003;3:745–756.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
103
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ. Signal transduction by the JNK group of MAP kinases. Cell. 2000;103:239–252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
104
-
-
2342562556
-
Mitogen-activated protein kinases in apoptosis regulation
-
Wada T, Penninger JM. Mitogen-activated protein kinases in apoptosis regulation. Oncogene. 2004;23:2838–2849.
-
(2004)
Oncogene
, vol.23
, pp. 2838-2849
-
-
Wada, T.1
Penninger, J.M.2
-
105
-
-
84859343404
-
HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module
-
Tang RX, Kong FY, Fan BF, et al. HBx activates FasL and mediates HepG2 cell apoptosis through MLK3-MKK7-JNKs signal module. World J Gastroenterol. 2012;18:1485–1495.
-
(2012)
World J Gastroenterol
, vol.18
, pp. 1485-1495
-
-
Tang, R.X.1
Kong, F.Y.2
Fan, B.F.3
-
106
-
-
84861205463
-
Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK)
-
Shajahan AN, Dobbin ZC, Hickman FE, et al. Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK). J Biol Chem. 2012;287:17682–17692.
-
(2012)
J Biol Chem
, vol.287
, pp. 17682-17692
-
-
Shajahan, A.N.1
Dobbin, Z.C.2
Hickman, F.E.3
-
107
-
-
2942532135
-
Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes
-
Hill MM, Adrain C, Duriez PJ, et al. Analysis of the composition, assembly kinetics and activity of native Apaf-1 apoptosomes. EMBO J. 2004;23:2134–2145.
-
(2004)
EMBO J
, vol.23
, pp. 2134-2145
-
-
Hill, M.M.1
Adrain, C.2
Duriez, P.J.3
-
108
-
-
0034525293
-
P38 Mitogen-activated protein kinase mediates tumor necrosis factor-α-induced apoptosis in rat fetal brown adipocytes 1
-
Valladares A, Alvarez AM, Ventura JJ, et al. P38 Mitogen-activated protein kinase mediates tumor necrosis factor-α-induced apoptosis in rat fetal brown adipocytes 1. Endocrinology. 2000;141:4383–4395.
-
(2000)
Endocrinology
, vol.141
, pp. 4383-4395
-
-
Valladares, A.1
Alvarez, A.M.2
Ventura, J.J.3
-
109
-
-
0037326526
-
Transforming growth factor-β1 (TGF-β)–induced apoptosis of prostate cancer cells involves Smad7-dependent Activation of p38 by TGF-β-activated kinase 1 and mitogen-activated protein kinase kinase 3
-
Edlund S, Bu S, Schuster N, et al. Transforming growth factor-β1 (TGF-β)–induced apoptosis of prostate cancer cells involves Smad7-dependent Activation of p38 by TGF-β-activated kinase 1 and mitogen-activated protein kinase kinase 3. Mol Biol Cell. 2003;14:529–544.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 529-544
-
-
Edlund, S.1
Bu, S.2
Schuster, N.3
-
110
-
-
0034714334
-
P38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide
-
Zhuang S, Demirs JT, Kochevar IE. P38 mitogen-activated protein kinase mediates bid cleavage, mitochondrial dysfunction, and caspase-3 activation during apoptosis induced by singlet oxygen but not by hydrogen peroxide. J Biol Chem. 2000;275:25939–25948.
-
(2000)
J Biol Chem
, vol.275
, pp. 25939-25948
-
-
Zhuang, S.1
Demirs, J.T.2
Kochevar, I.E.3
-
111
-
-
0035166964
-
P38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFβ-induced apoptosis in human Burkitt lymphoma B cells BL41
-
Schrantz N, Bourgeade MF, Mouhamad S, et al. P38-mediated regulation of an Fas-associated death domain protein-independent pathway leading to caspase-8 activation during TGFβ-induced apoptosis in human Burkitt lymphoma B cells BL41. Mol Biol Cell. 2001;12:3139–3151.
-
(2001)
Mol Biol Cell
, vol.12
, pp. 3139-3151
-
-
Schrantz, N.1
Bourgeade, M.F.2
Mouhamad, S.3
-
112
-
-
0037162507
-
Mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
-
Sarkar D, Su ZZ, Lebedeva IV, et al. Mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proc Natl Acad Sci USA. 2002;99:10054–10059.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 10054-10059
-
-
Sarkar, D.1
Su, Z.Z.2
Lebedeva, I.V.3
-
113
-
-
42749090537
-
MAPK regulate p53-dependent cell death induced by benzo [a] pyrene: involvement of p53 phosphorylation and acetylation
-
Lin T, Mak NK, Yang MS. MAPK regulate p53-dependent cell death induced by benzo [a] pyrene: involvement of p53 phosphorylation and acetylation. Toxicology. 2008;247:145–153.
-
(2008)
Toxicology
, vol.247
, pp. 145-153
-
-
Lin, T.1
Mak, N.K.2
Yang, M.S.3
-
114
-
-
0035008314
-
Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence
-
Clancy R, Rediske J, Koehne C, et al. Activation of stress-activated protein kinase in osteoarthritic cartilage: evidence for nitric oxide dependence. Osteoarthr Cartil. 2001;9:294–299.
-
(2001)
Osteoarthr Cartil
, vol.9
, pp. 294-299
-
-
Clancy, R.1
Rediske, J.2
Koehne, C.3
-
115
-
-
34548816723
-
Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage
-
Fan Z, Söder S, Oehler S, et al. Activation of interleukin-1 signaling cascades in normal and osteoarthritic articular cartilage. Am J Pathol. 2007;171:938–946.
-
(2007)
Am J Pathol
, vol.171
, pp. 938-946
-
-
Fan, Z.1
Söder, S.2
Oehler, S.3
-
116
-
-
0033851463
-
Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-jun N-terminal kinase, and nuclear factor κB: differential regulation of collagenase 1 and collagenase 3
-
Mengshol JA, Vincenti MP, Coon CI, et al. Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-jun N-terminal kinase, and nuclear factor κB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum. 2000;43:801–811.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 801-811
-
-
Mengshol, J.A.1
Vincenti, M.P.2
Coon, C.I.3
-
117
-
-
0037811204
-
Induction of matrix metalloproteinase-13 gene expression by TNF-α is mediated by MAP kinases, AP-1, and NF-κB transcription factors in articular chondrocytes
-
Liacini A, Sylvester J, Li WQ, et al. Induction of matrix metalloproteinase-13 gene expression by TNF-α is mediated by MAP kinases, AP-1, and NF-κB transcription factors in articular chondrocytes. Exp Cell Res. 2003;288:208–217.
-
(2003)
Exp Cell Res
, vol.288
, pp. 208-217
-
-
Liacini, A.1
Sylvester, J.2
Li, W.Q.3
-
118
-
-
0035040946
-
IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase
-
Kumar S, Votta BJ, Rieman DJ, et al. IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase. J Cell Physiol. 2001;187:294–303.
-
(2001)
J Cell Physiol
, vol.187
, pp. 294-303
-
-
Kumar, S.1
Votta, B.J.2
Rieman, D.J.3
-
119
-
-
58149237274
-
P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis
-
Brown KK, Heitmeyer SA, Hookfin EB, et al. P38 MAP kinase inhibitors as potential therapeutics for the treatment of joint degeneration and pain associated with osteoarthritis. J Inflamm (Lond). 2008;5:22.
-
(2008)
J Inflamm (Lond)
, vol.5
, pp. 22
-
-
Brown, K.K.1
Heitmeyer, S.A.2
Hookfin, E.B.3
-
120
-
-
0034767499
-
Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase
-
Pelletier JP, Fernandes JC, Jovanovic DV, et al. Chondrocyte death in experimental osteoarthritis is mediated by MEK 1/2 and p38 pathways: role of cyclooxygenase-2 and inducible nitric oxide synthase. J Rheumatol. 2001;28:2509–2519.
-
(2001)
J Rheumatol
, vol.28
, pp. 2509-2519
-
-
Pelletier, J.P.1
Fernandes, J.C.2
Jovanovic, D.V.3
-
121
-
-
3442886811
-
The pathophysiology of mitochondrial cell death
-
Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science. 2004;305:626–629.
-
(2004)
Science
, vol.305
, pp. 626-629
-
-
Green, D.R.1
Kroemer, G.2
-
122
-
-
0032575752
-
Mitochondria and apoptosis
-
Greenn DR, Reed JC. Mitochondria and apoptosis. Science. 1998;281:1309.
-
(1998)
Science
, vol.281
, pp. 1309
-
-
Greenn, D.R.1
Reed, J.C.2
-
123
-
-
45849117977
-
Oxidative phosphorylation: kinetic and thermodynamic correlation between electron flow, proton translocation, oxygen consumption and ATP synthesis under close to in vivo concentrations of oxygen
-
Reynafarje BD, Ferreira J. Oxidative phosphorylation: kinetic and thermodynamic correlation between electron flow, proton translocation, oxygen consumption and ATP synthesis under close to in vivo concentrations of oxygen. Int J Med Sci. 2008;5:143–151.
-
(2008)
Int J Med Sci
, vol.5
, pp. 143-151
-
-
Reynafarje, B.D.1
Ferreira, J.2
-
124
-
-
84874482858
-
Mitochondrial energetic metabolism – some general principles
-
Mazat JP, Ransac S, Heiske M, et al. Mitochondrial energetic metabolism – some general principles. IUBMB Life. 2013;65:171–179.
-
(2013)
IUBMB Life
, vol.65
, pp. 171-179
-
-
Mazat, J.P.1
Ransac, S.2
Heiske, M.3
-
125
-
-
68549083716
-
Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents
-
Kienhöfer J, Häussler DJ, Ruckelshausen F, et al. Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J. 2009;23:2034–2044.
-
(2009)
FASEB J
, vol.23
, pp. 2034-2044
-
-
Kienhöfer, J.1
Häussler, D.J.2
Ruckelshausen, F.3
-
126
-
-
57949087452
-
Molecular inflammation: underpinnings of aging and age-related diseases
-
Chung HY, Cesari M, Anton S, et al. Molecular inflammation: underpinnings of aging and age-related diseases. Ageing Res Rev. 2009;8:18–30.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 18-30
-
-
Chung, H.Y.1
Cesari, M.2
Anton, S.3
-
127
-
-
0031033421
-
Evidence for a negative Pasteur effect in articular cartilage
-
Urban J. Evidence for a negative Pasteur effect in articular cartilage. Biochem J. 1997;321:95–102.
-
(1997)
Biochem J
, vol.321
, pp. 95-102
-
-
Urban, J.1
-
128
-
-
84912010596
-
The role of mitochondrial reactive oxygen species in cartilage matrix destruction
-
Reed KN, Wilson G, Pearsall A, et al. The role of mitochondrial reactive oxygen species in cartilage matrix destruction. Mol Cell Biochem. 2014;397:195–201.
-
(2014)
Mol Cell Biochem
, vol.397
, pp. 195-201
-
-
Reed, K.N.1
Wilson, G.2
Pearsall, A.3
-
129
-
-
80053369081
-
Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response
-
Gardner BM, Walter P. Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response. Science. 2011;333:1891–1894.
-
(2011)
Science
, vol.333
, pp. 1891-1894
-
-
Gardner, B.M.1
Walter, P.2
-
130
-
-
58849154467
-
Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum
-
Hamamura K, Goldring MB, Yokota H. Involvement of p38 MAPK in regulation of MMP13 mRNA in chondrocytes in response to surviving stress to endoplasmic reticulum. Arch Oral Biol. 2009;54:279–286.
-
(2009)
Arch Oral Biol
, vol.54
, pp. 279-286
-
-
Hamamura, K.1
Goldring, M.B.2
Yokota, H.3
-
131
-
-
79959867275
-
Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage
-
Takada K, Hirose J, Senba K, et al. Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage. Int J Exp Pathol. 2011;92:232–242.
-
(2011)
Int J Exp Pathol
, vol.92
, pp. 232-242
-
-
Takada, K.1
Hirose, J.2
Senba, K.3
-
132
-
-
0346250162
-
Regulation of apoptosis by endoplasmic reticulum pathways
-
Breckenridge D, Germain M, Mathai JP, et al. Regulation of apoptosis by endoplasmic reticulum pathways. Oncogene. 2003;22:8608–8618.
-
(2003)
Oncogene
, vol.22
, pp. 8608-8618
-
-
Breckenridge, D.1
Germain, M.2
Mathai, J.P.3
-
133
-
-
84921901605
-
The role of endoplasmic reticulum stress in human pathology
-
Oakes SA, Papa FR. The role of endoplasmic reticulum stress in human pathology. Annu Rev Pathol. 2015;10:173–194.
-
(2015)
Annu Rev Pathol
, vol.10
, pp. 173-194
-
-
Oakes, S.A.1
Papa, F.R.2
-
134
-
-
37649016171
-
How IRE1 reacts to ER stress
-
Ron D, Hubbard SR. How IRE1 reacts to ER stress. Cell. 2008;132:24–26.
-
(2008)
Cell
, vol.132
, pp. 24-26
-
-
Ron, D.1
Hubbard, S.R.2
-
135
-
-
0035823579
-
Coupling endoplasmic reticulum stress to the cell death program mechanism of caspase activation
-
Rao RV, Hermel E, Castro-Obregon S, et al. Coupling endoplasmic reticulum stress to the cell death program mechanism of caspase activation. J Biol Chem. 2001;276:33869–33874.
-
(2001)
J Biol Chem
, vol.276
, pp. 33869-33874
-
-
Rao, R.V.1
Hermel, E.2
Castro-Obregon, S.3
-
136
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
Cullinan SB, Diehl JA. PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress. J Biol Chem. 2004;279:20108–20117.
-
(2004)
J Biol Chem
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
Diehl, J.A.2
-
137
-
-
73649128286
-
Akt-1 mediates survival of chondrocytes from endoplasmic reticulum-induced stress
-
Price J, Zaidi AK, Bohensky J, et al. Akt-1 mediates survival of chondrocytes from endoplasmic reticulum-induced stress. J Cell Physiol. 2010;222:502–508.
-
(2010)
J Cell Physiol
, vol.222
, pp. 502-508
-
-
Price, J.1
Zaidi, A.K.2
Bohensky, J.3
-
138
-
-
84867370364
-
Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes
-
Rasheed Z, Haqqi TM. Endoplasmic reticulum stress induces the expression of COX-2 through activation of eIF2α, p38-MAPK and NF-κB in advanced glycation end products stimulated human chondrocytes. Biochim Biophys Acta. 2012;1823:2179–2189.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 2179-2189
-
-
Rasheed, Z.1
Haqqi, T.M.2
-
139
-
-
24744438696
-
Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis
-
Yang L, Carlson SG, McBurney D, et al. Multiple signals induce endoplasmic reticulum stress in both primary and immortalized chondrocytes resulting in loss of differentiation, impaired cell growth, and apoptosis. J Biol Chem. 2005;280:31156–31165.
-
(2005)
J Biol Chem
, vol.280
, pp. 31156-31165
-
-
Yang, L.1
Carlson, S.G.2
McBurney, D.3
-
140
-
-
84903773914
-
Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein
-
Uehara Y, Hirose J, Yamabe S, et al. Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C/EBP homologous protein. Osteoarthr Cartil. 2014;22:1007–1017.
-
(2014)
Osteoarthr Cartil
, vol.22
, pp. 1007-1017
-
-
Uehara, Y.1
Hirose, J.2
Yamabe, S.3
-
141
-
-
84875818047
-
Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes
-
Yamabe S, Hirose J, Uehara Y, et al. Intracellular accumulation of advanced glycation end products induces apoptosis via endoplasmic reticulum stress in chondrocytes. FEBS J. 2013;280:1617–1629.
-
(2013)
FEBS J
, vol.280
, pp. 1617-1629
-
-
Yamabe, S.1
Hirose, J.2
Uehara, Y.3
-
143
-
-
84856693660
-
Extrapineal melatonin: analyses of its subcellular distribution and daily fluctuations
-
Venegas C, García JA, Escames G, et al. Extrapineal melatonin: analyses of its subcellular distribution and daily fluctuations. J Pineal Res. 2012;52:217–227.
-
(2012)
J Pineal Res
, vol.52
, pp. 217-227
-
-
Venegas, C.1
García, J.A.2
Escames, G.3
-
144
-
-
84905089096
-
Extrapineal melatonin: sources, regulation and potential functions
-
Acuña-Castroviejo D, Escames G, Venegas C, et al. Extrapineal melatonin: sources, regulation and potential functions. Cell Mol Life Sci. 2014;71:2997–3025.
-
(2014)
Cell Mol Life Sci
, vol.71
, pp. 2997-3025
-
-
Acuña-Castroviejo, D.1
Escames, G.2
Venegas, C.3
-
145
-
-
79960360982
-
A survey of molecular details in the human pineal gland in the light of phylogeny structure, function and chronobiological diseases
-
Stehle JH, Saade A, Rawashdeh O, et al. A survey of molecular details in the human pineal gland in the light of phylogeny structure, function and chronobiological diseases. J Pineal Res. 2011;51:17–43.
-
(2011)
J Pineal Res
, vol.51
, pp. 17-43
-
-
Stehle, J.H.1
Saade, A.2
Rawashdeh, O.3
-
146
-
-
0017281537
-
Nocturnal elevation of plasma melatonin and urinary 5-hydroxyindoleacetic acid in young men: attempts at modification by brief changes in environmental lighting and sleep and by autonomic drugs
-
Vaughan GM, Pelham RW, Pang SF, et al. Nocturnal elevation of plasma melatonin and urinary 5-hydroxyindoleacetic acid in young men: attempts at modification by brief changes in environmental lighting and sleep and by autonomic drugs. J Clin Endocrinol Metab. 1976;42:752–764.
-
(1976)
J Clin Endocrinol Metab
, vol.42
, pp. 752-764
-
-
Vaughan, G.M.1
Pelham, R.W.2
Pang, S.F.3
-
147
-
-
0033305177
-
High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus
-
Skinner DC, Malpaux B. High melatonin concentrations in third ventricular cerebrospinal fluid are not due to Galen vein blood recirculating through the choroid plexus. Endocrinology. 1999;140:4399–4405.
-
(1999)
Endocrinology
, vol.140
, pp. 4399-4405
-
-
Skinner, D.C.1
Malpaux, B.2
-
148
-
-
84936077755
-
Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow-Robin perivascular spaces
-
Reiter RJ, Tan DX, Kim SJ, et al. Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow-Robin perivascular spaces. Brain Struct Funct. 2014;219:1873–1887.
-
(2014)
Brain Struct Funct
, vol.219
, pp. 1873-1887
-
-
Reiter, R.J.1
Tan, D.X.2
Kim, S.J.3
-
149
-
-
0027210003
-
The melatonin rhythm: both a clock and a calendar
-
Reiter RJ. The melatonin rhythm: both a clock and a calendar. Experientia. 1993;49:654–664.
-
(1993)
Experientia
, vol.49
, pp. 654-664
-
-
Reiter, R.J.1
-
152
-
-
84956916027
-
Melatonin: the dawning of a treatment for fibrosis
-
Hu W, Ma Z, Jiang S, et al. Melatonin: the dawning of a treatment for fibrosis. J Pineal Res. 2016;60:121–131.
-
(2016)
J Pineal Res
, vol.60
, pp. 121-131
-
-
Hu, W.1
Ma, Z.2
Jiang, S.3
-
153
-
-
0025187950
-
Regulatory sites of the melatonin system of mammals
-
Krause DN, Dubocovich ML. Regulatory sites of the melatonin system of mammals. Trends Neurosci. 1990;13:464–470.
-
(1990)
Trends Neurosci
, vol.13
, pp. 464-470
-
-
Krause, D.N.1
Dubocovich, M.L.2
-
154
-
-
84893776367
-
Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal diseases and for use in bone-grafting procedures
-
Maria S, Witt-Enderby PA. Melatonin effects on bone: potential use for the prevention and treatment for osteopenia, osteoporosis, and periodontal diseases and for use in bone-grafting procedures. J Pineal Res. 2014;56:115–125.
-
(2014)
J Pineal Res
, vol.56
, pp. 115-125
-
-
Maria, S.1
Witt-Enderby, P.A.2
-
155
-
-
84896132010
-
Long-term effects of maternal separation on the responsiveness of the circadian system to melatonin in the diurnal nonhuman primate (Macaca mulatta)
-
Rawashdeh O, Dubocovich ML. Long-term effects of maternal separation on the responsiveness of the circadian system to melatonin in the diurnal nonhuman primate (Macaca mulatta). J Pineal Res. 2014;56:254–263.
-
(2014)
J Pineal Res
, vol.56
, pp. 254-263
-
-
Rawashdeh, O.1
Dubocovich, M.L.2
-
156
-
-
84899452426
-
Melatonin energy metabolism, and obesity: a review
-
Cipolla-Neto J, Amaral FG, Afech SC, et al. Melatonin energy metabolism, and obesity: a review. J Pineal Res. 2014;56:371–381.
-
(2014)
J Pineal Res
, vol.56
, pp. 371-381
-
-
Cipolla-Neto, J.1
Amaral, F.G.2
Afech, S.C.3
-
157
-
-
84934268769
-
Experimental and clinical aspects of melatonin and clock genes in diabetes
-
Peschke E, Bahr I, Muhlbauer E. Experimental and clinical aspects of melatonin and clock genes in diabetes. J Pineal Res. 2015;58:1–23.
-
(2015)
J Pineal Res
, vol.58
, pp. 1-23
-
-
Peschke, E.1
Bahr, I.2
Muhlbauer, E.3
-
158
-
-
84926294855
-
Melatonin redox activity: its potential clinical applications in neurodegenerative disorders
-
Miller E, Morel A, Saso L, et al. Melatonin redox activity: its potential clinical applications in neurodegenerative disorders. Curr Top Med Chem. 2015;15:163–169.
-
(2015)
Curr Top Med Chem
, vol.15
, pp. 163-169
-
-
Miller, E.1
Morel, A.2
Saso, L.3
-
159
-
-
84919625592
-
Melatonin feedback on clock genes: a theory involving the proteasome
-
Vriend J, Reiter RJ. Melatonin feedback on clock genes: a theory involving the proteasome. J Pineal Res. 2015;58:1–11.
-
(2015)
J Pineal Res
, vol.58
, pp. 1-11
-
-
Vriend, J.1
Reiter, R.J.2
-
160
-
-
84922826070
-
Systemic combined melatonin-mitochondria treatment improves acute respiratory distress syndrome in the rat
-
Sun CK, Lee FY, Kao YH, et al. Systemic combined melatonin-mitochondria treatment improves acute respiratory distress syndrome in the rat. J Pineal Res. 2015;58:137–150.
-
(2015)
J Pineal Res
, vol.58
, pp. 137-150
-
-
Sun, C.K.1
Lee, F.Y.2
Kao, Y.H.3
-
161
-
-
84926466801
-
Melatonin as a treatment for gastrointestinal cancer: a review
-
Xin Z, Jaing S, Yan X, et al. Melatonin as a treatment for gastrointestinal cancer: a review. J Pineal Res. 2015;58:375–387.
-
(2015)
J Pineal Res
, vol.58
, pp. 375-387
-
-
Xin, Z.1
Jaing, S.2
Yan, X.3
-
162
-
-
33845536018
-
One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species
-
Tan DX, Manchester LC, Terron MP, et al. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species. J Pineal Res. 2007;42:28–42.
-
(2007)
J Pineal Res
, vol.42
, pp. 28-42
-
-
Tan, D.X.1
Manchester, L.C.2
Terron, M.P.3
-
163
-
-
84896116486
-
Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review
-
García JJ, López-Pingarrón L, Almeida-Souza P, et al. Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review. J Pineal Res. 2014;56:225–237.
-
(2014)
J Pineal Res
, vol.56
, pp. 225-237
-
-
García, J.J.1
López-Pingarrón, L.2
Almeida-Souza, P.3
-
164
-
-
84899439162
-
A review of metal-catalyzed molecular damages: protection by melatonin
-
Romero A, Ramos E, de Los Ríos C, et al. A review of metal-catalyzed molecular damages: protection by melatonin. J Pineal Res. 2014;56:343–370.
-
(2014)
J Pineal Res
, vol.56
, pp. 343-370
-
-
Romero, A.1
Ramos, E.2
de Los Ríos, C.3
-
165
-
-
84919667055
-
Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physiochemical analysis
-
Galano A, Medina ME, Tan DX, et al. Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physiochemical analysis. J Pineal Res. 2015;58:107–116.
-
(2015)
J Pineal Res
, vol.58
, pp. 107-116
-
-
Galano, A.1
Medina, M.E.2
Tan, D.X.3
-
166
-
-
84919663655
-
Cardioprotective effects of melatonin against myocardial injuries induced by intermittent hypoxia in rats
-
Yeung HM, Hung MW, Lau CF. Cardioprotective effects of melatonin against myocardial injuries induced by intermittent hypoxia in rats. J Pineal Res. 2015;58:12–25.
-
(2015)
J Pineal Res
, vol.58
, pp. 12-25
-
-
Yeung, H.M.1
Hung, M.W.2
Lau, C.F.3
-
167
-
-
84922815620
-
Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis
-
Borges Lda S, Dermargos A, da Silva Junior EP, et al. Melatonin decreases muscular oxidative stress and inflammation induced by strenuous exercise and stimulates growth factor synthesis. J Pineal Res. 2015;58:166–172.
-
(2015)
J Pineal Res
, vol.58
, pp. 166-172
-
-
Borges Lda, S.1
Dermargos, A.2
da Silva Junior, E.P.3
-
169
-
-
39749108884
-
Medical implications of melatonin: receptor-mediated and receptor-independent actions
-
Reiter RJ, Tan DX, Manchester LC, et al. Medical implications of melatonin: receptor-mediated and receptor-independent actions. Adv Med Sci. 2007;52:11–28.
-
(2007)
Adv Med Sci
, vol.52
, pp. 11-28
-
-
Reiter, R.J.1
Tan, D.X.2
Manchester, L.C.3
-
170
-
-
84907841510
-
Local melatoninergic system as a protector of skin integrity
-
Slominski AT, Kleszczyński K, Semak I, et al. Local melatoninergic system as a protector of skin integrity. Int J Mol Sci. 2014;15:17705–17732.
-
(2014)
Int J Mol Sci
, vol.15
, pp. 17705-17732
-
-
Slominski, A.T.1
Kleszczyński, K.2
Semak, I.3
-
171
-
-
84958035144
-
Quinone reductase 2 as a promising target of melatonin therapeutic actions
-
Boutin JA. Quinone reductase 2 as a promising target of melatonin therapeutic actions. Expert Opin Ther Targets. 2016;20:303–317.
-
(2016)
Expert Opin Ther Targets
, vol.20
, pp. 303-317
-
-
Boutin, J.A.1
-
172
-
-
84895780831
-
Role of melatonin on production and preservation of gametes and embryos: a brief review
-
Cruz MH, Leal CL, da Cruz JF, et al. Role of melatonin on production and preservation of gametes and embryos: a brief review. Anim Reprod Sci. 2014;145:150–160.
-
(2014)
Anim Reprod Sci
, vol.145
, pp. 150-160
-
-
Cruz, M.H.1
Leal, C.L.2
da Cruz, J.F.3
-
173
-
-
23744513206
-
A proposed mechanism to explain the stimulatory effect of melatonin on antioxidant enzymes
-
Tomas-Zapico C, Coto-Montes A. A proposed mechanism to explain the stimulatory effect of melatonin on antioxidant enzymes. J Pineal Res. 2005;39:99–104.
-
(2005)
J Pineal Res
, vol.39
, pp. 99-104
-
-
Tomas-Zapico, C.1
Coto-Montes, A.2
-
174
-
-
79956339715
-
Melatonin protects human spermatozoa from apoptosis via melatonin receptor–and extracellular signal–regulated kinase-mediated pathways
-
Espino J, Ortiz Á, Bejarano I, et al. Melatonin protects human spermatozoa from apoptosis via melatonin receptor–and extracellular signal–regulated kinase-mediated pathways. Fertil Steril. 2011;95:2290–2296.
-
(2011)
Fertil Steril
, vol.95
, pp. 2290-2296
-
-
Espino, J.1
Ortiz, Á.2
Bejarano, I.3
-
175
-
-
0037204948
-
TNF-R1 signaling: a beautiful pathway
-
Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science. 2002;296:1634–1635.
-
(2002)
Science
, vol.296
, pp. 1634-1635
-
-
Chen, G.1
Goeddel, D.V.2
-
176
-
-
0029009910
-
Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex
-
Greenfeder SA, Nunes P, Kwee L, et al. Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex. J Biol Chem. 1995;270:13757–13765.
-
(1995)
J Biol Chem
, vol.270
, pp. 13757-13765
-
-
Greenfeder, S.A.1
Nunes, P.2
Kwee, L.3
-
177
-
-
62649139025
-
Immunological and inflammatory functions of the interleukin-1 family
-
Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol. 2009;27:519–550.
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 519-550
-
-
Dinarello, C.A.1
-
178
-
-
34848844641
-
Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components
-
Brikos C, Wait R, Begum S, et al. Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components. Mol Cell Proteomics. 2007;6:1551–1559.
-
(2007)
Mol Cell Proteomics
, vol.6
, pp. 1551-1559
-
-
Brikos, C.1
Wait, R.2
Begum, S.3
-
179
-
-
0037117543
-
IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase
-
Li S, Strelow A, Fontana EJ, et al. IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase. Proc Natl Acad Sci USA. 2002;99:5567–5572.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 5567-5572
-
-
Li, S.1
Strelow, A.2
Fontana, E.J.3
-
180
-
-
44049097129
-
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
-
Kawagoe T, Sato S, Matsushita K, et al. Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2. Nat Immunol. 2008;9:684–691.
-
(2008)
Nat Immunol
, vol.9
, pp. 684-691
-
-
Kawagoe, T.1
Sato, S.2
Matsushita, K.3
-
181
-
-
0029761275
-
TRAF6 is a signal transducer for interleukin-1
-
Cao Z, Xiong J, Takeuchi M, et al. TRAF6 is a signal transducer for interleukin-1. Nature. 1996;383:443–446.
-
(1996)
Nature
, vol.383
, pp. 443-446
-
-
Cao, Z.1
Xiong, J.2
Takeuchi, M.3
-
182
-
-
0029865142
-
IRAK: a kinase associated with the interleukin-1 receptor
-
Cao Z, Henzel WJ, Gao X. IRAK: a kinase associated with the interleukin-1 receptor. Science. 1996;271:1128–1131.
-
(1996)
Science
, vol.271
, pp. 1128-1131
-
-
Cao, Z.1
Henzel, W.J.2
Gao, X.3
-
183
-
-
77950367657
-
Two mechanistically and temporally distinct NF-κB activation pathways in IL-1 signaling
-
Yamazaki K, Gohda J, Kanayama A, et al. Two mechanistically and temporally distinct NF-κB activation pathways in IL-1 signaling. Sci Signal. 2009;2:ra66.
-
(2009)
Sci Signal
, vol.2
, pp. ra66
-
-
Yamazaki, K.1
Gohda, J.2
Kanayama, A.3
-
184
-
-
34249017742
-
Interleukin-1 (IL-1)-induced TAK1-dependent versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification
-
Yao J, Kim TW, Qin J, et al. Interleukin-1 (IL-1)-induced TAK1-dependent versus MEKK3-dependent NFκB activation pathways bifurcate at IL-1 receptor-associated kinase modification. J Biol Chem. 2007;282:6075–6089.
-
(2007)
J Biol Chem
, vol.282
, pp. 6075-6089
-
-
Yao, J.1
Kim, T.W.2
Qin, J.3
-
185
-
-
0346496017
-
Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3
-
Huang Q, Yang J, Lin Y, et al. Differential regulation of interleukin 1 receptor and Toll-like receptor signaling by MEKK3. Nat Immunol. 2004;5:98–103.
-
(2004)
Nat Immunol
, vol.5
, pp. 98-103
-
-
Huang, Q.1
Yang, J.2
Lin, Y.3
-
186
-
-
27744577296
-
TAK1, but not TAB 1 or TAB 2, plays an essential role in multiple signaling pathways in vivo
-
Shim J-H, Xiao C, Paschal AE, et al. TAK1, but not TAB 1 or TAB 2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 2005;19:2668–2681.
-
(2005)
Genes Dev
, vol.19
, pp. 2668-2681
-
-
Shim, J.-H.1
Xiao, C.2
Paschal, A.E.3
-
188
-
-
34547164540
-
The c-jun kinase/stress-activated pathway: regulation, function and role in human disease
-
Johnson GL, Nakamura K. The c-jun kinase/stress-activated pathway: regulation, function and role in human disease. Biochim Biophys Acta. 2007;1773:1341–1348.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1341-1348
-
-
Johnson, G.L.1
Nakamura, K.2
-
189
-
-
0037174934
-
JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery
-
Donovan N, Becker EB, Konishi Y, et al. JNK phosphorylation and activation of BAD couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem. 2002;277:40944–40949.
-
(2002)
J Biol Chem
, vol.277
, pp. 40944-40949
-
-
Donovan, N.1
Becker, E.B.2
Konishi, Y.3
-
190
-
-
0037860975
-
JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
-
Putcha GV, Le S, Frank S, et al. JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron. 2003;38:899–914.
-
(2003)
Neuron
, vol.38
, pp. 899-914
-
-
Putcha, G.V.1
Le, S.2
Frank, S.3
-
191
-
-
5444234359
-
Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis
-
Becker EB, Howell J, Kodama Y, et al. Characterization of the c-Jun N-terminal kinase-BimEL signaling pathway in neuronal apoptosis. J Neurosci. 2004;24:8762–8770.
-
(2004)
J Neurosci
, vol.24
, pp. 8762-8770
-
-
Becker, E.B.1
Howell, J.2
Kodama, Y.3
-
192
-
-
23044514254
-
Regulatory phosphorylation of Bim: sorting out the ERK from the JNK
-
Ley R, Ewings KE, Hadfield K, et al. Regulatory phosphorylation of Bim: sorting out the ERK from the JNK. Cell Death Differ. 2005;12:1008–1014.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1008-1014
-
-
Ley, R.1
Ewings, K.E.2
Hadfield, K.3
-
193
-
-
84872596242
-
Aging and vascular dysfunction: beneficial melatonin effects
-
Rodella LF, Favero G, Rossini C, et al. Aging and vascular dysfunction: beneficial melatonin effects. Age (Dordr). 2013;35:103–115.
-
(2013)
Age (Dordr)
, vol.35
, pp. 103-115
-
-
Rodella, L.F.1
Favero, G.2
Rossini, C.3
-
194
-
-
0029032902
-
Melatonin stimulates brain glutathione peroxidase activity
-
Barlow-Walden LR, Reiter RJ, Abe M, et al. Melatonin stimulates brain glutathione peroxidase activity. Neurochem Int. 1995;26:497–502.
-
(1995)
Neurochem Int
, vol.26
, pp. 497-502
-
-
Barlow-Walden, L.R.1
Reiter, R.J.2
Abe, M.3
-
195
-
-
0029385216
-
Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks
-
Pablos M, Agapito MT, Gutierrez R, et al. Melatonin stimulates the activity of the detoxifying enzyme glutathione peroxidase in several tissues of chicks. J Pineal Res. 1995;19:111–115.
-
(1995)
J Pineal Res
, vol.19
, pp. 111-115
-
-
Pablos, M.1
Agapito, M.T.2
Gutierrez, R.3
-
196
-
-
23744454194
-
Melatonin as an antioxidant: physiology versus pharmacology
-
Reiter RJ, Tan DX, Maldonado MD. Melatonin as an antioxidant: physiology versus pharmacology. J Pineal Res. 2005;39:215–216.
-
(2005)
J Pineal Res
, vol.39
, pp. 215-216
-
-
Reiter, R.J.1
Tan, D.X.2
Maldonado, M.D.3
-
197
-
-
0036482282
-
Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger
-
Tan DX, Reiter RJ, Manchester LC, et al. Chemical and physical properties and potential mechanisms: melatonin as a broad spectrum antioxidant and free radical scavenger. Curr Top Med Chem. 2002;2:181–197.
-
(2002)
Curr Top Med Chem
, vol.2
, pp. 181-197
-
-
Tan, D.X.1
Reiter, R.J.2
Manchester, L.C.3
-
198
-
-
0028821973
-
Melatonin reduces both basal and lipopolysaccharide-induced lipid peroxidation in vitro
-
Sewerynek E, Melchiorri D, Chen L, et al. Melatonin reduces both basal and lipopolysaccharide-induced lipid peroxidation in vitro. Free Radic Biol Med. 1995;19:903–909.
-
(1995)
Free Radic Biol Med
, vol.19
, pp. 903-909
-
-
Sewerynek, E.1
Melchiorri, D.2
Chen, L.3
-
199
-
-
47249119192
-
Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase
-
Lu T, Galijasevic S, Abdulhamid I, et al. Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase. Br J Pharmacol. 2008;154:1308–1317.
-
(2008)
Br J Pharmacol
, vol.154
, pp. 1308-1317
-
-
Lu, T.1
Galijasevic, S.2
Abdulhamid, I.3
-
200
-
-
0032878234
-
Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
-
Urata Y, Honma S, Goto S, et al. Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells. Free Radic Biol Med. 1999;27:838–847.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 838-847
-
-
Urata, Y.1
Honma, S.2
Goto, S.3
-
201
-
-
0036809371
-
Melatonin regulation of antioxidant enzyme expression
-
Mayo JC, Sainz RM, Antolin I, et al. Melatonin regulation of antioxidant enzyme expression. Cell Mol Life Sci. 2002;59:1706–1713.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 1706-1713
-
-
Mayo, J.C.1
Sainz, R.M.2
Antolin, I.3
-
202
-
-
84922335135
-
The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome
-
Vriend J, Reiter RJ. The Keap1-Nrf2-antioxidant response element pathway: a review of its regulation by melatonin and the proteasome. Mol Cell Endocrinol. 2015;401:213–220.
-
(2015)
Mol Cell Endocrinol
, vol.401
, pp. 213-220
-
-
Vriend, J.1
Reiter, R.J.2
-
203
-
-
79251554973
-
Melatonin–a pleiotropic, orchestrating regulator molecule
-
Hardeland R, Cardinali DP, Srinivasan V, et al. Melatonin–a pleiotropic, orchestrating regulator molecule. Prog Neurobiol. 2011;93:350–384.
-
(2011)
Prog Neurobiol
, vol.93
, pp. 350-384
-
-
Hardeland, R.1
Cardinali, D.P.2
Srinivasan, V.3
-
205
-
-
0001327186
-
Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum
-
Pozo D, Reiter RJ, Calvo JR, et al. Physiological concentrations of melatonin inhibit nitric oxide synthase in rat cerebellum. Life Sci. 1994;5:PL455–PL460.
-
(1994)
Life Sci
, vol.5
, pp. PL455-PL460
-
-
Pozo, D.1
Reiter, R.J.2
Calvo, J.R.3
-
206
-
-
0030930937
-
Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation and calmodulin
-
Pozo D, Reiter RJ, Calvo JR, et al. Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation and calmodulin. J Cell Biochem. 1997;65:430–442.
-
(1997)
J Cell Biochem
, vol.65
, pp. 430-442
-
-
Pozo, D.1
Reiter, R.J.2
Calvo, J.R.3
-
207
-
-
0037337314
-
Calreticulin-melatonin: an unexpected relationship
-
Macías M, Escames G, Leon J, et al. Calreticulin-melatonin: an unexpected relationship. Eur J Biochem. 2003;270:832–840.
-
(2003)
Eur J Biochem
, vol.270
, pp. 832-840
-
-
Macías, M.1
Escames, G.2
Leon, J.3
-
208
-
-
0038434113
-
Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in NIE-115 cells
-
Benitez-King G, Túnez I, Bellon A, et al. Melatonin prevents cytoskeletal alterations and oxidative stress induced by okadaic acid in NIE-115 cells. Exp Neurol. 2003;182:151–159.
-
(2003)
Exp Neurol
, vol.182
, pp. 151-159
-
-
Benitez-King, G.1
Túnez, I.2
Bellon, A.3
-
209
-
-
84883062692
-
Melatonin modulates cytoskeletal organization in the rat brain hippocampus
-
Jiménez-Rubio G, Ortíz-López L, Benítez-King G. Melatonin modulates cytoskeletal organization in the rat brain hippocampus. Neurosci Lett. 2012;51:47–51.
-
(2012)
Neurosci Lett
, vol.51
, pp. 47-51
-
-
Jiménez-Rubio, G.1
Ortíz-López, L.2
Benítez-King, G.3
-
212
-
-
34447558382
-
Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of α-synuclein
-
Lin AM, Fang SF, Chao PL, et al. Melatonin attenuates arsenite-induced apoptosis in rat brain: involvement of mitochondrial and endoplasmic reticulum pathways and aggregation of α-synuclein. J Pineal Res. 2007;43:163–171.
-
(2007)
J Pineal Res
, vol.43
, pp. 163-171
-
-
Lin, A.M.1
Fang, S.F.2
Chao, P.L.3
-
213
-
-
84901286029
-
Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice
-
Zhao H, Wu QQ, Cao LF, et al. Melatonin inhibits endoplasmic reticulum stress and epithelial-mesenchymal transition during bleomycin-induced pulmonary fibrosis in mice. PLoS ONE. 2014;9:e97266.
-
(2014)
PLoS ONE
, vol.9
-
-
Zhao, H.1
Wu, Q.Q.2
Cao, L.F.3
-
214
-
-
83555173352
-
Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes
-
Ji YL, Wang H, Meng C, et al. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes. J Pineal Res. 2012;52:71–79.
-
(2012)
J Pineal Res
, vol.52
, pp. 71-79
-
-
Ji, Y.L.1
Wang, H.2
Meng, C.3
-
215
-
-
84907907873
-
Melatonin reverses Fas, E2F-1 and endoplasmic reticulum stress mediated apoptosis and dysregulation of autophagy induced by the herbicide atrazine in murine splenocytes
-
Sharma S, Sarkar J, Haldar C, et al. Melatonin reverses Fas, E2F-1 and endoplasmic reticulum stress mediated apoptosis and dysregulation of autophagy induced by the herbicide atrazine in murine splenocytes. PLoS ONE. 2014;9:e108602.
-
(2014)
PLoS ONE
, vol.9
-
-
Sharma, S.1
Sarkar, J.2
Haldar, C.3
-
216
-
-
84925835440
-
Melatonin reduces endoplasmic reticulum stress and preserves sirtuin 1 expression in neuronal cells of newborn rats after hypoxia–ischemia
-
Carloni S, Albertini MC, Galluzzi L, et al. Melatonin reduces endoplasmic reticulum stress and preserves sirtuin 1 expression in neuronal cells of newborn rats after hypoxia–ischemia. J Pineal Res. 2014;57:192–199.
-
(2014)
J Pineal Res
, vol.57
, pp. 192-199
-
-
Carloni, S.1
Albertini, M.C.2
Galluzzi, L.3
-
217
-
-
79954421012
-
Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice
-
Wang H, Li L, Zhao M, et al. Melatonin alleviates lipopolysaccharide-induced placental cellular stress response in mice. J Pineal Res. 2011;50:418–426.
-
(2011)
J Pineal Res
, vol.50
, pp. 418-426
-
-
Wang, H.1
Li, L.2
Zhao, M.3
-
218
-
-
84866264061
-
Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway
-
Lim HD, Kim YS, Ko SH, et al. Cytoprotective and anti-inflammatory effects of melatonin in hydrogen peroxide-stimulated CHON-001 human chondrocyte cell line and rabbit model of osteoarthritis via the SIRT1 pathway. J Pineal Res. 2012;53:225–237.
-
(2012)
J Pineal Res
, vol.53
, pp. 225-237
-
-
Lim, H.D.1
Kim, Y.S.2
Ko, S.H.3
-
219
-
-
59149097227
-
Melatonin enhances cartilage matrix synthesis by porcine articular chondrocytes
-
Pei M, He F, Wei L, et al. Melatonin enhances cartilage matrix synthesis by porcine articular chondrocytes. J Pineal Res. 2009;46:181–187.
-
(2009)
J Pineal Res
, vol.46
, pp. 181-187
-
-
Pei, M.1
He, F.2
Wei, L.3
-
220
-
-
84892640329
-
Rescue of proinflammatory cytokine-inhibited chondrogenesis by the antiarthritic effect of melatonin in synovium mesenchymal stem cells via suppression of reactive oxygen species and matrix metalloproteinases
-
Liu X, Xu Y, Chen S, et al. Rescue of proinflammatory cytokine-inhibited chondrogenesis by the antiarthritic effect of melatonin in synovium mesenchymal stem cells via suppression of reactive oxygen species and matrix metalloproteinases. Free Radic Biol Med. 2014;68:234–246.
-
(2014)
Free Radic Biol Med
, vol.68
, pp. 234-246
-
-
Liu, X.1
Xu, Y.2
Chen, S.3
-
221
-
-
84904511802
-
Salutary effects of melatonin combined with treadmill exercise on cartilage damage
-
Hong Y, Kim H, Lee Y, et al. Salutary effects of melatonin combined with treadmill exercise on cartilage damage. J Pineal Res. 2014;57:53–66.
-
(2014)
J Pineal Res
, vol.57
, pp. 53-66
-
-
Hong, Y.1
Kim, H.2
Lee, Y.3
|